Top Senior Machine Learning Jobs in Louisville, KY

The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.

Serve as a customer-facing fraud and identity expert across pre-sales, onboarding, and expansion. Evaluate customer risk profiles, design fraud strategies and identity workflows, advise on risk mitigation and verification optimization, and coordinate technical, regulatory, and operational launch readiness. Lead implementation milestones, go-live planning, and cross-functional resolution of deployment bottlenecks while helping enterprise customers maximize adoption and long-term value.

Own the strategy, roadmap, and growth of Ottimate’s new product initiatives across procurement, budgeting, spend planning, and contract management. Lead customer discovery, validation, MVP development, launches, and portfolio metrics. Manage product managers and designers, oversee Design and UX, and partner with engineering, data science, sales, marketing, and customer success to deliver coherent, market-ready products.

Leads technical support for VA healthcare AI citizen developers, developing and validating supervised, unsupervised, and reinforcement learning models. Builds synthetic healthcare data cohorts, designs secure cloud-based data science workflows, collaborates with federal stakeholders, interprets analytical results, mentors developers, and ensures model quality, documentation, privacy, governance, and regulatory compliance.

Build and scale production AI systems for Prophetic’s real estate intelligence platform. Responsibilities include developing agentic systems, data pipelines, inference workflows, evaluation benchmarks, geospatial processing, and machine learning applications across hundreds of millions of records. The role requires shipping reliable Python services, optimizing throughput and cost, integrating research into products, and collaborating with engineering and product teams.

Leads the planning, design, specification, deployment, and scaling of advanced electrical, instrumentation, and automated test systems across manufacturing and laboratory environments. Coordinates equipment teams and test platform developers, evaluates sensors and technologies, supports NPI and DFMA/DFT initiatives, and converts test data into operational insights. Provides technical leadership, mentoring, troubleshooting, procurement support, and cross-functional program ownership while applying networking, software, data analysis, lean manufacturing, and Industry 4.0 technologies.

Lead design, build, and deploy scalable, reliable Java-based microservices in a cloud-native, event-driven AWS environment. Own backend feature design, code quality, automated testing, and FedRAMP release processes. Mentor engineers, participate in on-call/TechOps, integrate AI tools into development, and drive architecture, observability, and cross-team initiatives.

As a Customer Success Engineer, you'll drive adoption and satisfaction for enterprise customers using Deepgram's voice AI technology, fostering strong relationships and aligning technical solutions with business objectives.

Lead performance marketing data science initiatives focused on lead segmentation, bidding optimization, targeting, and marketing spend allocation. Develop and deploy production-ready machine learning systems, establish research and ML operations roadmaps, build monitoring frameworks, and identify high-impact opportunities. Partner with engineering, marketing, vendors, and executives while mentoring data scientists and machine learning engineers and promoting rigorous, maintainable, and reproducible practices.

Build and deploy AI agents, intelligent applications, scalable backend services, APIs, and full-stack solutions. Integrate large language models, AI services, data platforms, and external APIs into customer-focused products. Collaborate with engineering, product, and cross-functional teams while contributing to cloud-native applications, data pipelines, distributed systems, testing, deployment, and production operations.

Leads AI presales strategy, customer advisory, technical solution architecture, and team development. Translates business needs into AI use cases, prototypes, business cases, roadmaps, and repeatable offerings. Partners with sales, engineering, consultants, and technology vendors to support complex pursuits, executive briefings, demonstrations, proofs of concept, and AI business growth. Promotes responsible AI governance, tracks pipeline performance, develops thought leadership, and remains hands-on in high-impact customer engagements.

Lead and manage the underwriting and credit risk model validation team, perform hands-on independent validations of complex ML models, assess data integrity and performance, identify and remediate model weaknesses, partner on MRM framework improvements, and coordinate with audit, compliance, and controls to meet regulatory standards.

Drive new enterprise revenue and customer expansion by selling AI-powered SaaS solutions. Manage complex 6–12 month sales cycles, build executive relationships, develop value propositions, maintain pipeline accuracy, lead virtual account teams, and close high-value deals. Translate technical AI capabilities into measurable business outcomes, guide customer adoption, collaborate with marketing, product, and customer success teams, and exceed quarterly pipeline and revenue targets.

Lead product vision, strategy, discovery, and Agile delivery for insurance platforms. Partner with engineering, data science, design, QA, and insurance domain teams to prioritize opportunities, manage backlogs, evaluate build-versus-buy decisions, guide technical design, coordinate delivery, and measure outcomes. The role requires strong knowledge of insurance policy lifecycles, integrations, data modeling, pricing, underwriting, and AI-enabled workflows.

Leads product strategy, roadmap prioritization, AI and automation initiatives, client engagement, and cross-functional delivery for SPINS Intelligence and Portal. The role combines hands-on product management with PM team leadership, including writing user stories, defining acceptance criteria, triaging issues, reviewing sprint output, managing product economics, and developing business cases. Requires strong CPG, SaaS analytics, data product, AI/ML, and technical platform expertise.

Own Sophos EDR strategy, roadmap, technical product development, AI-powered experiences, and go-to-market execution. Translate customer needs, threat research, telemetry, competitive intelligence, and business goals into product priorities. Partner with engineering, security operations, threat research, marketing, sales, and customer success to deliver endpoint detection, investigation, threat hunting, response, reporting, and XDR/MDR upgrade capabilities while driving adoption, revenue, and customer outcomes.

Architect and prototype scalable solutions for Twilio’s emerging technologies experimentation team. Lead AI, machine learning, and LLM-driven initiatives; guide technical direction; mentor engineers across the US and India; align prototypes with business goals; and ensure enterprise architecture, scalability, extensibility, and production readiness. The role requires extensive architecture or principal engineering experience, cloud expertise across AWS and Azure, full-stack development knowledge, database expertise, and strong technical leadership.

Own the AI product strategy and roadmap for HealthEdge’s HealthRules Payer platform. Identify and prioritize AI use cases across claims, member management, enrollment, benefits, and contracts; translate strategy into product requirements; and align product, engineering, data science, UX, marketing, and sales teams. Lead AI governance, regulatory compliance, customer presentations, go-to-market messaging, pilots, and feature commercialization while ensuring responsible AI use in healthcare payer workflows.

Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.

Own the design vision and execution for experimental AI-powered learning tools co-created with teachers and researchers. Design teacher- and student-facing products, create flows, wireframes, interaction designs, and functional prototypes, and facilitate collaboration across educators, researchers, engineers, and data scientists. Conduct usability testing and validate research hypotheses while navigating ambiguity, data-heavy workflows, and uncertain AI/ML-enabled features.

Leads enterprise manufacturing AI, machine learning, and Industry 4.0 initiatives across multiple plants. Develops and deploys solutions for predictive maintenance, process and quality optimization, energy efficiency, throughput, and OEE improvement. Establishes scalable data and AI platforms, governance, and MLOps standards while integrating industrial data sources. Leads and mentors data science teams, prioritizes projects, allocates resources, partners with cross-functional manufacturing stakeholders, and presents strategic recommendations and business cases to executives.

Manage paid social campaigns and full-funnel strategies across Meta, LinkedIn, TikTok, Pinterest, Snapchat, and other paid channels. Oversee client accounts, analyze performance, identify growth opportunities, build client relationships, and collaborate with SEO, creative, and analytics teams. Contribute to thought leadership, coach associates, maintain quality standards, and explore automation, AI, and LLM search visibility initiatives.

Own the strategy, execution, customer success, and go-to-market for Oscilar’s Device and Behavior product. Lead development of SDKs, signal pipelines, behavioral biometrics, agentic identity signals, data networks, foundation-model capabilities, and analyst experiences. Partner with sales and customers to drive adoption, shape product positioning, and deliver a device intelligence and digital identity platform for fraud, onboarding, authentication, and risk decisions.

Supervise actuarial predictive modeling initiatives for insurance pricing, portfolio management, and planning. Collaborate with actuaries, data scientists, underwriters, and management to develop, validate, govern, and implement models. Establish assumptions, loss adjustments, usage guardrails, monitoring practices, and model documentation. Support regulatory filings, improve team workflows, contribute to strategic projects, and mentor staff in actuarial and technical skills.

Develop and maintain pricing and predictive models for credit insurance products. Analyze claims, loss ratios, portfolio performance, profitability, credit risk, and economic scenarios. Recommend pricing actions, support forecasting and reserves, evaluate underwriting strategies, and partner with underwriting, finance, claims, data science, and technology teams. Ensure model governance, documentation, and actuarial standards compliance.