Top Senior Machine Learning Jobs in Louisville, KY

Senior level
Artificial Intelligence • Edtech • Information Technology • Biotech
Lead a consortium advancing AI-driven neurodegeneration research: set strategy, build partnerships, manage multidisciplinary executive team, oversee product development and deployment, secure funding, ensure ethical AI and scientific integrity, and scale the platform to broader biomedical domains.
Top Skills: AIData GovernanceFederated Data ArchitecturesMachine LearningPrivacy-Preserving Technologies
Reposted 6 Days AgoSaved
Remote
Louisville, KY
216K-324K Annually
Senior level
216K-324K Annually
Senior level
Information Technology • Consulting
Lead strategy and execution for MarketScan data products and delivery experiences. Define portfolio vision, prioritize data product innovation and operational excellence, drive cloud and AI enablement, ensure data quality/compliance, engage executives and customers, and build a high-performing product organization to grow adoption and revenue.
Top Skills: AIAnalyticsAutomationCi/CdCloudData GovernanceData PipelinesDe-IdentificationMachine Learning
Reposted 11 Days AgoSaved
Remote or Hybrid
Louisville, KY
160K-195K Annually
Senior level
160K-195K Annually
Senior level
AdTech • Consumer Web • Digital Media • eCommerce • Marketing Tech
The Senior Software Engineer will design and optimize recommendation algorithms, maintain data pipelines, and improve personalized user experiences using machine learning techniques and backend engineering skills.
Top Skills: AirflowApache KafkaAws SagemakerBeamDockerElasticsearchFlinkGcp Vertex AiGrafanaJaxKibanaKubernetesNode.jsPythonPyTorchSparkTensorFlowTypescript
Reposted 11 Days AgoSaved
Easy Apply
Remote
Louisville, KY
Easy Apply
232K-310K Annually
Senior level
232K-310K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
As a Senior Staff Machine Learning Engineer at Affirm, you will lead complex ML system design and implementation, mentor engineers, and drive innovative ML strategies for financial services.
Top Skills: KubeflowMlflowPythonPyTorchRaySparkXgboost
Reposted 11 Days AgoSaved
Remote
Louisville, KY
230K-368K Annually
Senior level
230K-368K Annually
Senior level
Cloud • Fintech • Food • Information Technology • Software • Hospitality
As a Principal Software Engineer, you'll architect and code backend services and ML models, integrate them with Salesforce, and mentor junior engineers.
Top Skills: AWSGoJavaLambdaLangchainPythonSagemakerSalesforceSqs
6 Days AgoSaved
Remote
Louisville, KY
128K-267K Annually
Senior level
128K-267K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Design, implement, and scale ML-based solutions for search and advertising; define data collection, evaluation, and production serving strategies; analyze data to inform development; communicate cross-functionally; produce technical reports; and stay current with advances in LLMs, vision models, and generative AI.
Top Skills: Deep LearningGenerative AiJavaLarge Language ModelsMachine LearningNatural Language ProcessingPythonVision Models
6 Days AgoSaved
Remote
Louisville, KY
171K-201K Annually
Senior level
171K-201K Annually
Senior level
Fintech • Analytics • Financial Services
Design, build, and scale backend systems and APIs for high-transaction consumer products. Collaborate with product, credit, compliance, support, and analytics teams. Contribute to code reviews, technical planning, security, and operational excellence. Mentor peers and promote engineering best practices.
Top Skills: .Net (C#)APIsAugmentCursorFactoryMachine Learning
Reposted 6 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Software • Analytics
Lead the development of generative AI tools for fashion, guiding ML engineers, and implementing innovative AI systems and workflows.
Top Skills: AWSAzureClip-Like ArchitecturesCloud Gpu PlatformsComputer VisionDiffusion ModelsGCPGenerative AiLlmsMachine LearningMultimodal AiMultimodal Embeddings
Reposted 6 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Software • Analytics
As a Senior Machine Learning Engineer, you will enhance diffusion models, conduct research, collaborate on system implementations, and communicate findings effectively.
Top Skills: AIAWSAzureDeep LearningDiffusion ModelsGansGCPMachine LearningMultimodal LlmsPyTorchVaes
Reposted 6 Days AgoSaved
Remote
Louisville, KY
110K-140K Annually
Senior level
110K-140K Annually
Senior level
Artificial Intelligence • HR Tech • Machine Learning • Social Impact • Software • Consulting
The Senior Customer Success Manager drives revenue growth by ensuring customer satisfaction, building strong relationships, managing renewals, and promoting product solutions aligned with client goals.
Top Skills: Artificial IntelligenceHr TechnologyMachine LearningSaaS
7 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Professional Services
Design and implement data-centric cybersecurity solutions: develop ML algorithms and automation for security tools; discover, parse, map, and transform legacy RMF artifacts into OSCAL; migrate and analyze security data; reproduce dashboards/workflows in eGRC; collaborate with Professional Services; produce migration assessments and reports.
Top Skills: AgileAIAws GovcloudD3FendEgrcIaasMachine LearningExcelMicrosoft WordMitre Att&CkOscalRmfSaaSScriptingSdlcSharepointSIEMSoarSsp
Reposted 7 Days AgoSaved
Remote
Louisville, KY
140K-190K Annually
Senior level
140K-190K Annually
Senior level
Fitness • Healthtech • Software
Lead strategy and execution for AI-powered nutrition and coaching features. Define product roadmap, partner with engineering/data/design, run experiments and evaluations, ship 0-to-1 ML products, and ensure responsible AI practices and measurable user impact.
Top Skills: A/B TestingComputer VisionLlmsMachine LearningPersonalization EnginesPrompt EngineeringRecommendation Systems
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7 Days AgoSaved
Remote or Hybrid
Louisville, KY
170K-220K Annually
Senior level
170K-220K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
Lead product development for Socure's core fraud platform: build reusable services, APIs, and ML-powered features (graph, signals, model lifecycle). Drive prioritization, cross-functional delivery, KPI definition, customer discovery, and integration to improve detection accuracy and operational performance across fraud products.
Top Skills: Address ValidationAIAPIsData PlatformsDecisioning SystemsGraph IntelligenceMachine LearningModel LifecycleName MatchingSignals
7 Days AgoSaved
Remote
Louisville, KY
99K-117K Annually
Senior level
99K-117K Annually
Senior level
Real Estate
Lead BI analytics and governance for client accounts: manage BI analysts, deliver dashboards and reports, oversee data mapping, modeling, quality, and platform initiatives (Power BI/Databricks), advise stakeholders, drive analytics roadmap, and apply advanced analytics and ML to optimize workplace and portfolio insights.
Top Skills: AIAlteryxDatabricksETLMachine LearningPower BISQLTabular Model
Reposted 7 Days AgoSaved
Remote
Louisville, KY
160K-185K Annually
Senior level
160K-185K Annually
Senior level
Artificial Intelligence • Mobile • Software
Design, build, and operate production-grade AI systems using ML, LLMs, RAG, and agentic workflows. Define evaluation strategies, implement data/retrieval/orchestration layers, apply MLOps/LLMOps, and partner with stakeholders to prioritize, monitor, troubleshoot, and improve AI solutions balancing quality, latency, cost, reliability, and maintainability.
Top Skills: Agentic AiCloud-Native DeploymentComputer VisionContext EngineeringData PipelinesData PlatformsDistributed SystemsExperimentationGraph DatabasesHuman-In-The-LoopLarge Language Models (Llms)LlmopsMachine LearningMlopsModel Fine-TuningMonitoringObservabilityOrchestrationPrompt EngineeringPythonRetrieval-Augmented Generation (Rag)Vector Databases
Reposted 7 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
HR Tech • Professional Services • Consulting
Lead the integration of AI and digital solutions in manufacturing processes, driving adoption and measurable impact on efficiency, quality, and performance.
Top Skills: AIAWSAzureErpGCPIotMachine LearningMesPower BIPythonScadaSQLTableau
Reposted 7 Days AgoSaved
In-Office or Remote
Louisville, KY
225K-260K Annually
Senior level
225K-260K Annually
Senior level
Robotics
Develop and scale machine learning training systems for robotics data, optimize training pipelines, and collaborate with ML researchers to enhance autonomy models.
Top Skills: Distributed Training FrameworksMachine LearningNeural NetworksPython
Reposted 7 Days AgoSaved
In-Office or Remote
Louisville, KY
Senior level
Senior level
Biotech
Build and scale core components of an end-to-end proteomics software stack (LIMS, data pipelines, web portal). Design agentic backends and AI-augmented tooling, develop analysis algorithms and lab integrations, deploy cloud IaC and CI/CD, write tests and monitoring, and collaborate with R&D, operations, and customers to productionize tools for high-throughput proteomics.
Top Skills: APIsBenchlingCi/CdClaude CodeCloud Data InfrastructureCursorCytometersData LakesData PipelinesElnFlow CytometryInfrastructure As CodeLimsLiquid HandlersLlmsMachine LearningMass SpectrometryMcp ServersMonitoring And AnalyticsNgsPythonRagRobotic Lab AutomationVisualization Layers
Reposted 7 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Big Data • Food • Mobile • Payments
The Principal Product Manager - Growth will lead growth initiatives, focusing on user engagement, retention, and the use of AI to enhance product strategies and experiences.
Top Skills: AIMachine Learning
Reposted 7 Days AgoSaved
In-Office or Remote
Louisville, KY
118K-203K Annually
Senior level
118K-203K Annually
Senior level
Information Technology
The Senior Technical Architect will lead AI SDLC transformations, create architectural solutions, mentor teams, and drive innovation in regulated industries.
Top Skills: AIAWSAzureDevOpsGCPMachine LearningSdlc
Reposted 7 Days AgoSaved
Remote
Louisville, KY
200K-215K Annually
Senior level
200K-215K Annually
Senior level
Software
As a Regional Sales Director, you'll lead a sales team, develop business plans, and drive sales growth by managing complex cycles and nurturing talent.
Top Skills: CloudMachine LearningSaaSSecurity
8 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Payments • Software
Design and scale fraud-mitigation strategies for buyer, seller, and account fraud across Stripe products. Monitor portfolios, identify and predict risky behavior, propose controls, automate workflows, collaborate with Product/Engineering/Data Science, and educate users to minimize losses while enabling growth.
Top Skills: Ai ToolsMachine LearningPythonRSQL
8 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Fintech • Machine Learning • Software • Financial Services
Lead product lifecycle for internal PaaS and Data-as-a-Service offerings focused on SRE and data engineering. Drive system reliability (99.99% availability), scaling strategies, GCP cost optimization, BigQuery/table and ETL performance, AI/ML enablement, and data governance/compliance across cross-functional teams.
Top Skills: AIAWSBigQueryBusiness IntelligenceCloud IamData LakeData WarehouseEltETLFinopsGCPGkeGoogle Cloud PlatformKubernetesMachine LearningSite Reliability EngineeringSreTerraform
8 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Financial Services
Lead credit and funding decisioning for auto lending partners, exercising delegated lending and funding authority, resolving exceptions and stipulations, feeding performance insights to product and risk teams, conducting win/loss analysis, and enabling dealer-facing operations and training to protect portfolio performance and improve approval workflows.
Top Skills: Ai ToolsJd Power PinMachine LearningMarket Data Platforms
Reposted 8 Days AgoSaved
Remote or Hybrid
Louisville, KY
147K-161K Annually
Senior level
147K-161K Annually
Senior level
Artificial Intelligence • Big Data • Fintech • Security • Software
Manage a portfolio of enterprise and mid-market North American customers to drive adoption, retention, expansion, and measurable ROI for Jumio's identity verification SaaS. Monitor health signals, build success plans, lead business reviews, partner cross-functionally, handle escalations, and ensure customers achieve outcomes tied to renewals and expansion.
Top Skills: AmlAPIsAutomationBiometricsGainsightIdentity VerificationKycLiveness DetectionMachine LearningPlanhatTotango
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