Top Senior Python Jobs in Jacksonville, FL

Reposted 15 Hours AgoSaved
Remote
Jacksonville, FL
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 2 Days AgoSaved
Remote
Jacksonville, FL
Senior level
Senior level
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills: DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Reposted 2 Days AgoSaved
In-Office or Remote
Jacksonville, FL
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
Reposted 16 Days AgoSaved
Easy Apply
Remote or Hybrid
Jacksonville, FL
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
21 Days AgoSaved
Remote
Jacksonville, FL
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Reposted 16 Hours AgoSaved
In-Office or Remote
Jacksonville, FL
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Reposted YesterdaySaved
Remote
Jacksonville, FL
Senior level
Senior level
Healthtech • Software
Lead and code fullstack features for the EVV team, provide technical leadership and mentoring, design and execute automated tests, monitor and troubleshoot production, contribute to product technical roadmap, and leverage AI-assisted development tools.
Top Skills: AWSCi/CdClaudeCursorDockerGitJavaScriptPHPPytestPythonSQLSqlalchemyVue
Reposted YesterdaySaved
Remote
Jacksonville, FL
Senior level
Senior level
Software
Lead the design and development of scalable Python backend services and APIs on AWS, mentor engineers, and manage PostgreSQL databases in a healthcare technology environment.
Top Skills: Api GatewayAWSBitbucketDockerGitJIRAKubernetesLambdaOauth 2PostgresPythonRest ApiSlackTeams
2 Days AgoSaved
Remote
Jacksonville, FL
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Develop, test, and maintain a complex distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements. Work with distributed workloads (Spark/Hadoop), SQL/Snowflake, AWS, shell scripting, and job scheduling/process automation. Support delivery under Agile/SAFe practices and ensure alignment with program standards.
Top Skills: AWSBash/Shell ScriptingDroolsHadoopJavaLinux (Cli)OdmPythonSnowflakeSparkSQLVs Code
2 Days AgoSaved
Remote
Jacksonville, FL
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Lead Software Engineer responsible for designing, developing, testing, and maintaining a distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements, implement cloud and big-data solutions (Spark/Hadoop), and ensure program standards and reliable delivery.
Top Skills: SparkAWSDroolsHadoopIbm OdmJavaLinuxPythonShell ScriptingSnowflakeSQLVisual StudioVs Code
Reposted 2 Days AgoSaved
Remote
Jacksonville, FL
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization, contribute across products, write APIs, and drive AI-accelerated software development workflows.
Top Skills: .NetAgent OrchestrationAi-Assisted DevelopmentLlm ToolingPython
Reposted 2 Days AgoSaved
Remote
Jacksonville, FL
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization. Contribute across Python and .NET ecosystems, write APIs, review code, and support AI-accelerated development workflows while collaborating in a remote team environment.
Top Skills: .NetAi-Assisted Development WorkflowsClaude CodeLlm ToolingMulti-Agent SystemsPython
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Reposted 2 Days AgoSaved
Remote
Jacksonville, FL
180K-190K Annually
Senior level
180K-190K Annually
Senior level
Artificial Intelligence • Food • Software
The Senior Full Stack Engineer will develop scalable web applications using Python and React.js, mentor team members, and enhance system performance while leveraging AI technologies. The role emphasizes collaboration, end-to-end feature ownership, and architectural improvements in a remote setting.
Top Skills: AWSCi/CdClaude CodeCodexDatadogDockerGithub ActionsGraphQLMySQLNew RelicPostgresPythonReactRestful ApisSentrySQL
Reposted 2 Days AgoSaved
Remote
Jacksonville, FL
4K-5K Hourly
Senior level
4K-5K Hourly
Senior level
Travel
Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.
Top Skills: Ai Coding AssistantsAWSDjangoFastapiGitPostgresPythonRailway
Reposted 2 Days AgoSaved
In-Office or Remote
Jacksonville, FL
Senior level
Senior level
Digital Media
Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.
Top Skills: ApolloAWSDjangoDjango OrmGraphQLNextjsPythonReact
8 Days AgoSaved
Remote or Hybrid
Jacksonville, FL
Senior level
Senior level
Digital Media • Social Media • Software • Design
Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.
Top Skills: Python
8 Days AgoSaved
In-Office or Remote
Jacksonville, FL
Senior level
Senior level
Agency • Information Technology
Design, build, test, and maintain backend applications using FastAPI and SQLAlchemy. Implement database schemas, integrate front-end components, optimize for performance and scalability, debug issues, participate in code reviews, and collaborate on feature design. Maintain clean, testable code and stay current with best practices.
Top Skills: FastapiGitMySQLOraclePytestPythonSQLSqlalchemy
Reposted 11 Days AgoSaved
Remote
Jacksonville, FL
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
Reposted 11 Days AgoSaved
Remote
Jacksonville, FL
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
Reposted 11 Days AgoSaved
Remote
Jacksonville, FL
90-110 Annually
Senior level
90-110 Annually
Senior level
Digital Media • Professional Services • Consulting • Financial Services
The Senior Python Developer will enhance commerce and communication infrastructure by developing features, collaborating with stakeholders, ensuring system reliability, and integrating with third-party tools, while maintaining high-performance standards.
Top Skills: Ci/CdDockerFastapiPostgresPythonRabbitMQRedisStripe
Reposted 13 Days AgoSaved
Remote
Jacksonville, FL
100K-200K Annually
Senior level
100K-200K Annually
Senior level
Artificial Intelligence • HR Tech • Information Technology • Software
As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.
Top Skills: AWSCeleryFastapiOpensearchPostgresPythonRedisTemporal
24 Days AgoSaved
In-Office
Jacksonville, FL
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.
Top Skills: AirflowAWSCloudwatchDatabricksDatadogEcsElasticacheLambdaLlmMachine LearningPythonScalaSnsSparkSqsTerraform
24 Days AgoSaved
In-Office
Jacksonville, FL
104K-196K Annually
Senior level
104K-196K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and optimize event-driven, distributed backend systems and APIs in Python for large-scale content metadata extraction and enrichment. Deploy and operate resilient AWS-based pipelines, collaborate with ML teams to integrate models, and ensure system performance, observability, and data integrity.
Top Skills: AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
24 Days AgoSaved
In-Office
Jacksonville, FL
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and scale event-driven, distributed backend systems in Python to extract and enrich metadata at massive scale. Lead architecture, mentor engineers, integrate ML/LLM components, optimize performance, and ensure observability and reliability across AWS-based pipelines.
Top Skills: AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
Reposted 15 Days AgoSaved
Remote
Jacksonville, FL
125K-200K Annually
Senior level
125K-200K Annually
Senior level
Software • Cybersecurity
The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.
Top Skills: Automation ScriptsCi/CdDevOpsPythonSastWebhook Implementations
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