Top Senior HR Jobs in Charleston, SC

Reposted 10 Days AgoSaved
Remote
Charleston, SC
140K-170K Annually
Senior level
140K-170K Annually
Senior level
Cloud • Security
Senior HR Business Partner supporting GTM across the Americas. Serve as trusted advisor to leaders, manage full employee lifecycle, drive talent and succession planning, support headcount and people-cost planning, analyze HR metrics, lead HR programs for growth and retention, and coach managers to improve performance.
Top Skills: BobChatgptClaudeGoogle WorkspaceTrinet
Reposted 11 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Agency • Healthtech • Professional Services • Pharmaceutical
Provide HR generalist support for headquarters and remote employees, focusing on employee relations, investigations, performance management, FMLA/ADA/workers' comp administration, HRIS recordkeeping, legal compliance, policy development, and manager consultation. Handle employee inquiries on benefits and 401(k), maintain records, and assist with trainings and documentation to ensure regulatory and corporate compliance.
Reposted 11 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Agency • Healthtech • Professional Services • Pharmaceutical
Provide administrative and operational HR support including onboarding/offboarding, recruitment administration, HRIS records maintenance, reporting, training documentation, compliance assistance, and responding to routine employee inquiries while handling confidential information and managing multiple priorities in a fully remote environment.
Top Skills: HrisExcelMicrosoft OutlookMicrosoft PowerpointMicrosoft Word
14 Days AgoSaved
Remote
Charleston, SC
110K-130K Annually
Senior level
110K-130K Annually
Senior level
Software
Owns the end-to-end HR function for a distributed U.S. and New Zealand organization. Responsibilities include HR strategy, employee lifecycle processes, payroll oversight, HRIS selection and implementation, policies, internal controls, compliance, employee relations, performance management, compensation, benefits, recruiting, and onboarding. The role partners closely with the CFO, executives, managers, Finance, external counsel, vendors, and New Zealand HR support to build a scalable HR operating model.
Top Skills: DeelHris
Reposted 12 Days AgoSaved
Remote
Charleston, SC
90-150 Hourly
Senior level
90-150 Hourly
Senior level
Professional Services • Consulting
Lead client engagements on benefits strategy, plan design, open enrollment, and administration. Stabilize operations, manage carriers/brokers, execute transitions and platform migrations, ensure compliance, advise on cost optimization and multi-state/global expansion, and expand client relationships.
Top Skills: DeelGustoHrisJustworksPaylocityPeo EnvironmentsRemote.ComRippling
Reposted 12 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology
The Head of HR strategically leads all HR functions, fostering a positive workplace culture while managing talent acquisition, employee relations, and compliance.
Top Skills: Hr Software
Reposted 12 Days AgoSaved
Remote or Hybrid
Charleston, SC
Senior level
Senior level
Information Technology • Consulting
Assist higher education clients in enhancing HR operations as an HR leader. Responsibilities include oversight of projects, training, and aligning HR processes.
Top Skills: BannerEllucian ColleagueHigher Education ErpJenzabarWorkday
13 Days AgoSaved
Remote
Charleston, SC
232K-290K Annually
Senior level
232K-290K Annually
Senior level
Healthtech • Biotech
Partners with Global Medical Affairs and Commercial Development leaders to develop people strategies supporting organizational effectiveness, growth, and global commercialization. Advises on workforce planning, organizational design, talent development, change leadership, employee engagement, HR initiatives, and employee relations. Collaborates with HR centers of excellence and other HRBPs to implement scalable processes, strengthen culture, and support organizational transformation.
Top Skills: Excel
14 Days AgoSaved
Remote
Charleston, SC
140K-185K Annually
Senior level
140K-185K Annually
Senior level
Big Data • Machine Learning • Software • Analytics
Serves as the strategic HR partner to Customer Experience leaders across Customer Success, Professional Services, Support, and Renewals. Leads organizational design, workforce planning, talent management, leadership coaching, employee relations, change management, compensation, succession planning, and engagement initiatives. Uses workforce and business insights to improve organizational effectiveness, support transformation, and align people strategies with GTM priorities. Partners across the People Team and mentors HR colleagues.
14 Days AgoSaved
In-Office or Remote
Charleston, SC
90K-100K Annually
Senior level
90K-100K Annually
Senior level
Edtech
Designs and maintains Oracle HCM reporting, HR and talent scorecards, dashboards, extracts, and ad hoc people analytics. Owns reporting definitions, catalogs, refresh schedules, data validation, and governance while partnering with HR leaders, HR Systems, and Power BI teams. Translates ambiguous business needs into accurate reporting solutions and delivers insights on headcount, turnover, compensation, and workforce operations. This individual contributor role requires strong HR data stewardship, stakeholder consulting, and technical reporting expertise.
Top Skills: BipHcm ExtractsExcelOracle Hcm CloudOtbiPower BIServicenowSQLUkg
14 Days AgoSaved
In-Office or Remote
Charleston, SC
130K-195K Annually
Senior level
130K-195K Annually
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Generative AI
Partner with senior leaders across a global technology organization to guide organizational design, leadership development, talent and succession planning, engagement, retention, capability building, and people strategy. The role supports a rapidly scaling AI company, combines strategic advising with hands-on execution, and helps build scalable People practices across distributed teams and regions.
14 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Fintech • Financial Services
Serve as a strategic HR partner to leaders in a high-growth SaaS company. Build performance, accountability, culture, leadership judgment, and internal communication systems from the ground up. Coach managers through ambiguous and sensitive employee situations, advise on organizational health, and strengthen consistency across the leadership layer. Partner with HR Operations and the HRBP Lead while using AI to improve HR and company-wide efficiency.
Top Skills: AI
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14 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Edtech • Information Technology • Social Impact • Software
Manage day-to-day, multi-state HR operations including leave and accommodation administration, onboarding and offboarding, I-9 verification, background checks, employment compliance, contractor records, HRIS administration, reporting, employee inquiries, and documentation. Support filings, unemployment claims, garnishments, performance reviews, and HR and Finance administrative processes while maintaining accurate, confidential records.
Top Skills: AcaAdaEeo-1Form 5500HrisI-9Paychex
14 Days AgoSaved
In-Office or Remote
Charleston, SC
125K-285K Annually
Senior level
125K-285K Annually
Senior level
Cloud • Information Technology • Consulting
Leads the global HR workstream for acquisitions, divestitures, and outsourcing transactions. Advises business, legal, finance, and corporate development leaders on people impacts, due diligence, risks, valuation, contracting, integration planning, compliance, employee communications, retention, and organizational change. Coordinates cross-functional HR teams, manages complex timelines, oversees client transitions, and continuously improves the HR M&A operating model and playbook.
Top Skills: Workday
Reposted 14 Days AgoSaved
Remote
Charleston, SC
80K-100K Hourly
Senior level
80K-100K Hourly
Senior level
Social Impact
Lead HR strategy and operations: employee relations, conflict resolution, performance management, onboarding, pay equity audits, training, policy compliance, and HR reporting. Partner with executive leadership and board to align HR with organizational goals and maintain confidential personnel records.
Reposted 15 Days AgoSaved
Remote
Charleston, SC
125K-183K Annually
Senior level
125K-183K Annually
Senior level
Artificial Intelligence • Healthtech
Senior HR Business Partner will embed with people managers to lead goal-setting and OKRs, build and deliver manager training, coach on employee relations and org design, audit goal quality, and automate People operations using existing tools and AI to improve manager capability and operational efficiency.
Reposted 20 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology • Consulting
The HR Business Partner will collaborate with employees and leaders to implement HR initiatives, improve engagement, manage talent processes, and provide guidance on HR matters.
Top Skills: MS Office
21 Days AgoSaved
Remote
Charleston, SC
100K-130K Annually
Senior level
100K-130K Annually
Senior level
Healthtech
Lead full-cycle recruiting and talent strategy as a strategic partner to hiring managers. Build long-term candidate pipelines, source active and passive talent, use AI tools to accelerate recruiting, maintain Greenhouse data and metrics, train managers, and improve recruiting infrastructure and employer branding.
Top Skills: ChatgptClaudeGreenhouseLinkedin Recruiter
21 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology • Professional Services • Consulting
Provide end-to-end federal recruitment and staffing support including job analyses, writing and posting vacancy announcements, assessing applications, issuing certificates, coordinating offers and pre-appointment requirements, ensuring compliance with OPM/HHS/FDA policies, responding to applicants and stakeholders, and maintaining case files and records.
Top Skills: HrisExcelMicrosoft PowerpointMicrosoft WordUsa Staffing
Reposted 22 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Professional Services • Consulting
Conscious Talent seeks experienced people leaders to shape HR strategies, build inclusive cultures, and support organizational growth, integrating personal development values in their work.
Reposted 22 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Travel • Hospitality
The HR Officer supports onboard leadership in strengthening culture through HR policies, manages employee relations, ensures compliance, and partners with management to meet business needs.
Top Skills: ExcelPowerPointWord
Reposted 22 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Social Impact
The HR Business Partner collaborates with management to improve employee focus and productivity, aligning HR strategies with company goals and overseeing HR functions.
Top Skills: Human Resource Information SystemsMicrosoft Office Suite
Reposted 22 Days AgoSaved
Remote
Charleston, SC
100K-150K Annually
Senior level
100K-150K Annually
Senior level
Information Technology • Business Intelligence • Consulting
The HR Manager will lead HR strategies, manage employee relations, oversee talent management, ensure compliance, and support global workforce operations.
Top Skills: AtsHrisRippling
Reposted 22 Days AgoSaved
Remote
Charleston, SC
140K-180K Annually
Senior level
140K-180K Annually
Senior level
Software
The Principal HR Business Partner will collaborate with Go-To-Market leaders, designing people strategies, supporting organizational design, and enhancing team performance across various functions in the Americas.
Top Skills: AIAtsHris
Reposted 23 Days AgoSaved
Remote
Charleston, SC
95K-120K Annually
Senior level
95K-120K Annually
Senior level
Healthtech
Partner with clinical leaders to align people strategies with operational goals across a multi-state clinical workforce. Lead employee relations, performance management, workforce planning, compliance, and retention initiatives for field-based clinical and non-clinical teams, ensuring multi-state legal compliance and support for high-acuity patient populations.
Top Skills: E-Verify
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