Top Senior Software Engineer Jobs in Charleston, SC

Reposted 13 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Retail • Sports
Design, implement, and maintain scalable Java-based software solutions. Collaborate across the SDLC with stakeholders and development teams, integrate DevOps and CI/CD practices, support operational tasks, ensure security and performance, drive feature development, conduct code reviews, and stay current with emerging technologies.
Top Skills: Ci/CdCloud PlatformsContainerizationDevOpsJavaMicroservices
Reposted 13 Days AgoSaved
Remote
Charleston, SC
151K-189K Annually
Senior level
151K-189K Annually
Senior level
Financial Services
Design, build, and architect stablecoin and crypto infrastructure; integrate DEXs, DeFi protocols, and wallet providers; develop smart contract interactions; expand crypto product functionality and asset selection; collaborate cross-functionally; establish crypto development standards and ensure security and reliability for large-scale user experiences.
Top Skills: AmmsDefi ProtocolsDexsEthereumEthers.JsEvmJavaKey ManagementKotlinLayer 2Multi-SignaturePythonReactReact NativeRuby On RailsSmart Contract DevelopmentStablecoinsSvmWeb3.Js
Reposted 13 Days AgoSaved
Remote
Charleston, SC
147K-276K Annually
Senior level
147K-276K Annually
Senior level
Artificial Intelligence • Software
Technical leader for Platform & Infrastructure building scalable, resilient cloud-native systems to support large AI workloads. Define architecture, mentor engineers, solve systemic infrastructure bottlenecks, design foundational platform services, and collaborate cross-functionally to ensure secure, high-performance operations.
Top Skills: Data LineageData RegistriesFederated AccessGCPGpu InfrastructureGpu SchedulingHigh-Performance NetworkingKubernetesSoc2
Reposted 13 Days AgoSaved
Remote
Charleston, SC
173K-324K Annually
Senior level
173K-324K Annually
Senior level
Artificial Intelligence • Software
Lead architecture and scaling of cloud-native infrastructure to support large AI workloads. Mentor engineers, decompose complex systems, design foundational platform services, and collaborate with product, research, and security teams to ensure secure, performant, and highly available GPU/ML infrastructure.
Top Skills: Cloud-Native InfrastructureGCPGpu InfrastructureGpu SchedulingHigh-Performance NetworkingKubernetes
Reposted One Month AgoSaved
Remote
Charleston, SC
140K-180K Annually
Senior level
140K-180K Annually
Senior level
Greentech • Energy • Renewable Energy
Build and maintain end-to-end web applications powering sales and operations. Design tools for quoting, scheduling, and fulfillment, integrate AI into products, collaborate on UX, ship high-impact features, and contribute to architecture, deployment, and engineering culture.
Top Skills: AIDjangoJavaScriptPostgresPythonReactRemixRenderTypescript
Reposted One Month AgoSaved
Remote
Charleston, SC
180K-250K Annually
Senior level
180K-250K Annually
Senior level
Energy • Renewable Energy
Design, build, and maintain data platform tools, ensuring data quality and integrity. Collaborate with data science teams and enforce best software practices.
Top Skills: AirflowAlloydbBeamBigQueryBigtableClickhouseDagsterDatabricksDbtFabricFlinkGcp Pub/SubGcsHadoopHbaseHiveIcebergJavaKafkaKinesisNatsPostgresPrestoPythonRedshiftRustS3ScalaSnowflakeSparkTemporalTinybirdTrino
Reposted One Month AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Insurance
The Software Engineer will build features across the stack, design AI/LLM-driven workflows, translate requirements, and collaborate closely with the founding team and customers.
Top Skills: Amazon DynamodbAmazon EcsAWSAws LambdaFastapiNextjsPostgresPythonReactS3Typescript
Reposted One Month AgoSaved
Remote
Charleston, SC
175K-230K Annually
Senior level
175K-230K Annually
Senior level
Fintech • Software • Financial Services
The Senior Full-Stack Software Engineer will design, build, and scale backend services and APIs for financial transactions while collaborating with frontend engineers and contributing to technical design.
Top Skills: AWSDjangoPostgresPythonReactTypescript
Reposted 14 Days AgoSaved
Remote
Charleston, SC
110K-140K Annually
Senior level
110K-140K Annually
Senior level
Insurance • Software
The role involves leading frontend development, maintaining UI components, overseeing CI/CD pipelines, mentoring engineers, and enhancing application performance in collaboration with cross-functional teams.
Top Skills: CSSEslintGitGitlabHTMLJestPlaywrightPrettierReactTypescriptViteVitestVue
Reposted 14 Days AgoSaved
In-Office or Remote
Charleston, SC
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Artificial Intelligence • Professional Services • Consulting • Automation
Lead design and delivery of enhancements to a next-generation AI agent platform. Own large features and infrastructure, mentor engineers, set technical standards, drive cross-team initiatives, improve reliability and SLOs, and influence product and process decisions to scale systems supporting millions of interactions.
Top Skills: Ai/Ml PlatformsDistributed SystemsGoJavaOpen ApisRustService-Level Objectives (Slos)
Reposted 14 Days AgoSaved
Remote
Charleston, SC
200K-200K Annually
Senior level
200K-200K Annually
Senior level
Cloud • Information Technology • Software • Infrastructure as a Service (IaaS)
As a Senior Software Engineer, you will build and operate Upbound Spaces, resolve issues in SaaS environments, develop features, support project lifecycles, manage Kubernetes services, and enhance operational tools.
Top Skills: GoGrafanaKubernetesOpentelemetryPrometheus
Reposted 14 Days AgoSaved
Remote
Charleston, SC
10-10 Annually
Senior level
10-10 Annually
Senior level
Artificial Intelligence • Financial Services
This role involves owning and evolving the backend platform for AI employees, mentoring engineers, optimizing system performance, and driving architectural decisions at Supernal.
Top Skills: CeleryDatadogDjangoDramatiqGCPHelmKedaKubernetesOpentelemetryPostgresPythonRabbitMQRedisTerraform
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Reposted 14 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Cloud • Software • Database
The Senior Software Engineer will lead design for large cloud platform projects, troubleshoot system issues, and mentor engineers, focusing on scalability and reliability.
Top Skills: Cloud-NativeGoKubernetesReactSaaS
Reposted 14 Days AgoSaved
Remote
Charleston, SC
190K-230K Annually
Senior level
190K-230K Annually
Senior level
Artificial Intelligence • Legal Tech • Software
The Staff Engineer will lead the Systems team, design scalable cloud infrastructure, optimize data pipelines, and ensure platform reliability and security.
Top Skills: ElasticsearchGCPKafkaKubernetesLinuxPostgresPub/SubPythonRubyTerraform
Reposted 14 Days AgoSaved
Remote
Charleston, SC
145K-195K Annually
Senior level
145K-195K Annually
Senior level
Artificial Intelligence • Logistics • Transportation
As a Senior Software Engineer, you will design and implement AI technologies to address complex logistics challenges and mentor team members.
Top Skills: AIGithub CopilotNextjsOcrQuickbooksReactTms SystemsTypescript
Reposted 14 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Digital Media • Social Media • Software • Sports
As a Staff Backend Engineer at FloSports, you'll lead backend development initiatives, focusing on scalable distributed systems, authentication frameworks, and mentoring engineers while collaborating with product teams for technical solutions.
Top Skills: Aws (AuroraDockerDynamoDBFastifyJestKubernetesLambdaNestjsNode.jsNoSQLS3)SQLSupertestTypescriptVitest
Reposted 14 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Healthtech
Design, implement, and optimize core frontend, backend, and model-integration components. Drive engineering direction, ship and scale LLM-powered applications, build robust APIs and streaming systems, establish CI/CD and instrumentation, and deliver production-grade agentic workflows with measurable reliability and performance.
Top Skills: Api DesignAWSAzureCi/CdGCPLarge Language Models (Llms)Node.jsReactStreamingTypescript
Reposted 14 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Cloud • Information Technology • Software • Cybersecurity
Lead the design and implementation of APIs, develop data pipelines, and mentor teams on AI integration and Agile methodologies.
Top Skills: .NetAzureAzure DevopsDockerGitKubernetesNode.jsPysparkPythonSQL
Reposted 14 Days AgoSaved
Remote
Charleston, SC
248K-310K Annually
Senior level
248K-310K Annually
Senior level
Real Estate • Travel • PropTech
Lead technical strategy and architecture for a large-scale Content Platform that powers marketing campaigns. Solve ambiguous cross-team problems, design scalable backend and AI-driven systems, mentor senior engineers, and partner with product, design, and marketing to drive execution and engineering standards across the org.
Top Skills: Agentic/Ai-Driven SystemsGraphQLJavaKotlinLanggraphMicroservice ArchitectureNosql DatabasesRedisRelational Databases
Reposted 14 Days AgoSaved
Remote
Charleston, SC
290K-340K Annually
Senior level
290K-340K Annually
Senior level
Software
Lead the creation of an AI-powered software generation platform, partner with AI and infrastructure teams, and define success metrics to enhance developer experience.
Top Skills: Ai Coding ToolsCi PipelinesPrompt OptimizationVirtualized Environments
Reposted 14 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology
Lead design and delivery of self-service platform capabilities: provisioning, deployment, observability, and multi-region networking. Drive RFCs and cross-team alignment, build APIs (primarily in Go), implement Terraform/GitOps flows, improve EKS reliability and Grafana-based SLOs, and reduce operational toil via safe, auditable automation. Own on-call rotation and platform adoption outcomes.
Top Skills: Argo CdCanariesCniEksEnvoyEnvoy GatewayGithub ActionsGitopsGoGrafana CloudKubernetesLinuxNetworkingOpentelemetryPrometheusService MeshTerraform
Reposted 14 Days AgoSaved
Remote
Charleston, SC
170K-190K Annually
Senior level
170K-190K Annually
Senior level
Hardware • Machine Learning • Security • Software
Lead frontend architecture and execution for high-traffic Search features using React and TypeScript. Build map-based visualizations, optimize client-side performance and state management, collaborate with product/design/backend, conduct code reviews, mentor peers, and ship production-grade web features.
Top Skills: AWSGoogle Maps ApiGraphQLGrpcMapboxNode.jsPostgresReactRestTypescript
Reposted 14 Days AgoSaved
Remote
Charleston, SC
138K-244K Annually
Senior level
138K-244K Annually
Senior level
Healthtech
The Senior Software Engineer will design and develop backend systems and APIs, mentor other engineers, and resolve complex integration challenges in healthcare technology.
Top Skills: DockerGoJavaKubernetesMongoDBMySQLPostgresPythonRuby
Reposted 14 Days AgoSaved
Remote
Charleston, SC
195K-263K Annually
Senior level
195K-263K Annually
Senior level
Software
The Senior Software Engineer will build and operate systems for Vanta's FedRAMP environments, focusing on reliability, compliance, and incident response, while collaborating with product teams and improving operational readiness.
Top Skills: AWSEcsFargateGithub ActionsMongoDBNode.jsReactTypescript
Reposted 14 Days AgoSaved
Remote
Charleston, SC
140K-170K Annually
Senior level
140K-170K Annually
Senior level
Manufacturing
The role involves designing, developing, and maintaining iOS applications, driving technical architecture, and promoting knowledge sharing within the team.
Top Skills: Ci/CdGitGraphQLSwiftSwiftui
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