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Top Senior Software Engineer Jobs in Charleston, SC
AdTech • Digital Media • eCommerce • Marketing Tech • Mobile • Software
Design and build services, APIs, frameworks, and UIs; lead development of user interfaces and features; collaborate with teams on core platforms; contribute to backend services and data models.
Top Skills:
Aws EcsDockerGoNode.jsReactTypescript
Artificial Intelligence • Software
Design and implement solutions for a scalable AI platform. Troubleshoot technical issues and ensure software quality through testing and architecture improvements.
Top Skills:
AIDistributed SystemsPython
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Artificial Intelligence
Build and improve application and developer infrastructure for a FedRAMP-high US environment: support US-specific hosting/on-call, enhance auth/RBAC, feature-flag tooling, CI/CD, monitoring, and developer experience while collaborating across engineering teams.
Top Skills:
AWSAws CliCi/Cd/Deployment PipelinesDockerFeature FlagsHelm (Helmcharts)KubernetesLoggingMonitoringMonorepoPythonRbacRelational DatabasesTypescript
Cloud • Enterprise Web • Information Technology • Software • Consulting • Design • App development
Responsibilities include modernizing POS and fuel system software, troubleshooting issues, collaborating with team members, and ensuring system reliability in high-transaction environments.
Top Skills:
.NetC#C++DockerGitWindows
Healthtech • Software
Lead design, architecture, and hands-on implementation of scalable healthcare SaaS systems. Drive interoperability (HL7, FHIR, EDI), mentor engineers, liaise with stakeholders, manage technical risk, and ensure quality, performance, security, and innovation.
Top Skills:
AgileAWSC#DevOpsEdiFhirHl7JavaMicroservicesMirth ConnectNoSQLPostgresPythonSaaSServerlessSQL Server
Healthtech
Design and build core LLM platform primitives, safety and observability infrastructure, provider abstraction and evaluation systems, prompt lifecycle and Agent-as-a-Service; collaborate with product teams, document reference implementations, and lead technical standards to enable other engineers to build production AI features.
Top Skills:
AnthropicAws EventbridgeAws FargateAws Parameter StoreAws S3ClaudeCodexCovalDockerDynamoDBGeminiGithub ActionsLangfuseNestjsNewrelicOpenaiOpenai Agents SdkPostgresPrismaRdsRedisSonarqubeSqsSseTypescriptVercel Ai SdkVitestWebsockets
eCommerce • Logistics • Transportation
Design and develop software applications for logistics and supply chain operations, collaborating with teams to enhance service offerings and ensure robust functionality.
Top Skills:
AWSAzureC#JavaPython
Software
Lead the architecture of Commerce Hub by defining core domain models, building intricate systems, and mentoring engineers while influencing product strategy.
Top Skills:
AICRMDistributed SystemsFinancial Models
Machine Learning • Biotech • Agriculture
As a Senior Software Engineer, you will build software for carbon dioxide removal efforts, focusing on full-stack development and optimizing complex workflows.
Top Skills:
LiveviewPhoenixPostgisPostgresReactSQLTypescript
Reposted 5 Days AgoSaved
Security • Cybersecurity
The role involves leading initiatives for managing federal cloud environments, focusing on DevOps best practices, infrastructure reliability, and mentoring junior engineers.
Top Skills:
AWSGoKafkaKubernetesPythonRedisTerraform
Software
The Staff Software Engineer will design and implement user-facing features, architect systems, ensure code quality, and integrate modern tools in a fast-paced environment.
Top Skills:
AWSDatadogDockerFigmaGitKubernetesLinearMetabaseMongoDBNext.JsNode.jsNotionOpensearchPostgresPosthogReactSentrySlackTailwindTemporalTypescript
Reposted 5 Days AgoSaved
Easy Apply
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Database • Analytics
Build AI/ML-powered features across ClickHouse Cloud, designing scalable APIs, integrating inference systems and vector DBs, implementing frontend interfaces, and ensuring production-grade monitoring, versioning, and observability for model deployments.
Top Skills:
AWSAzureClickhouseClickhouse CloudGCPInference ApisJavaScriptPythonReactTypescriptVector Databases
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Food • Healthtech • Telehealth
As a Senior Software Engineer, you will develop backend systems for Foodsmart's platform, collaborate with teams, and uphold coding standards.
Top Skills:
AWSDockerDynamoDBEc2JavaScriptKubernetesLambdaMySQLNode.jsNoSQLPostgresRdsSQLSqsTypescript
Software
Lead design and implementation of scalable .NET Core + Angular applications. Communicate with stakeholders, estimate work, drive agile delivery, ensure code quality, mentor engineers, and collaborate across product, QA, and design to deliver client-facing solutions.
Top Skills:
.Net CoreAngular 18Aws CognitoAws LambdaAws SqsAws Step FunctionsCi/Cd PipelinesContainerizationFigmaMonorepoPythonSalesforce IntegrationUnit TestingUx Design
Other
Develop and maintain scalable, cloud-based platform services. Enhance reliability and observability, automate infrastructure, provide technical leadership, and improve operational excellence across teams.
Top Skills:
ArgocdAWSAzureC#DatadogDockerGithub ActionsGoGCPJavaJenkinsKubernetesPrometheusTerraformTerragrunt
Other
The Sr Software Development Engineer will design and maintain scalable cloud-based solutions, lead project technical direction, and ensure high-quality deliverables in a fast-paced Agile environment.
Top Skills:
AngularAWSAzureC#CypressGCPKubernetesModern Javascript FrameworksPlaywrightReactSelenium
Artificial Intelligence • Cloud • Software • Cybersecurity
Design, build, and maintain high-scale data ingestion pipelines. Collaborate with product management to define requirements and deploy resources in cloud data providers.
Top Skills:
AWSAws SamAzureCloudFormationDatabricksGrafanaPythonSentrySnowflakeSplunkTerraform
Software
Technical leader designing scalable APIs and agent interfaces for autonomous advertising agents. Build high-throughput real-time systems, evaluate agent protocols, drive architecture, mentor engineers, and integrate external ad platforms.
Top Skills:
A2AAi Agent FrameworksApi VersioningAuthenticationAWSBigQueryCloud StorageEvent-Driven SystemsGCPGoGraphQLMcpNode.jsPostgresPythonRedisRestTypescript
eCommerce • Retail • Software
The Staff Software Engineer will lead technical projects, develop full-stack software, mentor teams, and drive product direction at Propel, focusing on impactful solutions.
Top Skills:
JavaScriptPython
Healthtech • Other • Software
As a Senior Software Developer at TherapyNotes, you will design and build features across the tech stack, mentor junior developers, and contribute to architecture decisions while solving complex technical problems.
Top Skills:
AngularAsp.Net CoreC#CSSHTMLJavaScriptPostgresTypescript
Energy • Manufacturing • Solar • Renewable Energy
The Staff Software Engineer leads technical development, designs features, collaborates across teams, and ensures software quality in an agile environment.
Top Skills:
AngularApache Commons SuiteC# .NetCSSHTML5JavaJavaScriptJqueryMavenMySQLOraclePostgresSpring FrameworkSQL Server
Cloud • Security • Software
As a Staff Software Engineer at Chainguard, you will be responsible for designing and implementing features end-to-end, collaborating with product teams, and contributing to AI-driven products while ensuring software supply chain security.
Top Skills:
Ai ToolingArtifact RegistriesCi/Cd SystemsContainersDockerGoGoKubernetes
Artificial Intelligence • Automotive • Machine Learning • Transportation
The Senior Software Engineer will develop metrics and tools for evaluating autonomous vehicle performance, ensuring data quality, and collaborating with multidisciplinary teams.
Top Skills:
AIData Visualization ToolsGitMachine Learning TechniquesPythonSimulation Environments
Cloud • Security • Software
The Senior Frontend Engineer will focus on building high-performance web applications and key UI components for Libraries while collaborating with backend and product teams to deliver complex features.
Top Skills:
GraphQLMaterial UiReact
Insurance
The Senior Software Engineer role involves designing, developing, and maintaining full-stack serverless systems, collaborating with teams, mentoring peers, and driving software solutions for injury management.
Top Skills:
Ai FeaturesAWSCloud-Native SolutionsLlmsNo-SqlServerlessSQLTypescript
Top Companies in Charleston, SC Hiring Senior Software Engineers Roles
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