Top Senior Software Engineer Jobs in Charleston, SC

The Senior Software Engineer will design and develop backend systems and APIs, mentor other engineers, and resolve complex integration challenges in healthcare technology.

The Senior Software Engineer will build and operate systems for Vanta's FedRAMP environments, focusing on reliability, compliance, and incident response, while collaborating with product teams and improving operational readiness.

The role involves designing, developing, and maintaining iOS applications, driving technical architecture, and promoting knowledge sharing within the team.

Own and modernize core data infrastructure and pipelines to ensure accurate usage capture, transformation, and monetization. Contribute to architecture, maintain integrations with billing/CRM/payment platforms, evolve customer account UIs, and improve legacy Laravel systems while collaborating across a distributed team.

The Senior Software Engineer will develop backend systems, mentor engineers, and collaborate with cross-functional teams while contributing to product features and roadmaps.

As a Senior Software Engineer at Upwave, you will build scalable backend systems, develop APIs, and engineer data pipelines while collaborating with product and data science teams.

Provide technical leadership across the simulation platform: define architecture, drive feature delivery, debug complex multi-module issues, conduct code reviews, collaborate on QA/CI/CD, and mentor engineers to modernize and maintain the legacy Windows desktop codebase.

Design, build, and operate high-concurrency distributed microservices for spam detection and email delivery. Lead architecture, CI/CD, cloud-native (GCP) operations, telemetry, and AI-assisted/agentic workflows. Integrate LLMs for detection and diagnostics, mentor engineers, and drive reliability, performance, and automation across production systems.

Lead architecture and hands-on implementation of an offline-first edge computing platform in Go. Design distributed messaging and cloud-to-edge synchronization, optimize services for resource-constrained in-store hardware, maintain Kubernetes/Helm deployments, mentor engineers, and collaborate with Product and DevOps for phased rollouts and migrations.

Design and build systems for managing bare-metal infrastructure, focusing on automation, hardware provisioning, and software integration with Linux systems.

We are seeking a Senior Frontend Software Engineer to build advanced web applications using JavaScript and ReactJS, collaborating with a team to enhance user experiences.

The Senior Backend Software Engineer will build intricate backend systems, develop APIs, ensure high availability, and improve application scalability and performance.

Lead and manage software engineering teams, architect scalable systems, and innovate solutions while collaborating with stakeholders across various technology stacks.

Build and evolve Stratusphere, an agentic cloud optimization platform spanning web applications, backend services, infrastructure, data pipelines, and agent tooling. Review and improve AI-generated code, architecture, testing, reliability, observability, and safety. Collaborate with engineering, product, customer success, and customers to deliver measurable solutions, improve agent workflows, and influence the roadmap. Own work end to end while maintaining documentation, change control, communication, and operational standards.

Develop and expand software products and platforms across backend, frontend, cloud, AI, and machine learning systems. Build efficient, reliable, and testable code; collaborate with business partners to launch features; influence product and engineering decisions; mentor team members; and help shape team culture and product vision in an agile environment.

As a Staff Full Stack Engineer, you will lead complex projects for the lending platform, mentor engineers, and drive system optimization while collaborating with cross-functional teams.

Lead full‑stack development of microservices-based case management and workflow automation for DoD systems. Build REST APIs, responsive front ends, CI/CD pipelines, and cloud IL2–IL5 deployments while ensuring DISA STIG/RMF compliance, data protection, performance optimization, automated testing, Agile delivery, documentation, mentoring, and Tier 3 support during critical incidents.

As a Senior Software Engineer, you'll build high-performing, scalable applications for Joyride's auction platform, working on new features and existing code.

Build scalable, secure, high-performance applications for clients, clinicians, and internal users. Collaborate across Product and Clinical Operations, translate workflows into impactful features, improve architecture and system stability, and contribute to design, testing, code reviews, and technical planning. Lead cross-functional projects, mentor junior developers, and help shape innovative technology supporting mental healthcare.

Design, implement, test, deploy, and operate core protocol features and Rust-based consensus clients. Own full lifecycle delivery, build conformance and adversarial tests, execute safe protocol upgrades, resolve availability/performance issues, and collaborate cross-functionally while maintaining high standards for correctness and security.

Design, build, and maintain payment integrations and a reconciliation data platform for high-volume restaurant transactions. Implement terminal-to-cloud flows, ingestion pipelines, matching engines, reporting UIs, and payment analytics. Provide technical leadership, documentation, and mentor teammates to ensure reliable settlement and reconciliation.

Lead technical direction for patient-facing mobile and web products, rapidly prototype and ship features with product/design/clinical teams, mentor engineers, set architecture and development standards, and use AI tools to improve patient engagement, retention, and outcomes.

Design and build internal platforms, tooling, and AI-powered workflows to reduce developer friction, improve velocity, quality, and reliability. Partner with product, infra, and security to create reusable paved paths, measure impact with engineering metrics, and help define the Developer Experience practice.

Lead design and delivery of end-to-end calibration systems for perception sensors and robot kinematics. Build algorithms, fixtures, on-fixture software, data pipelines, validation, operator workflows, and fleet monitoring. Own fixture software and in-field self-check/recalibration, define downstream manufacturing requirements, and coordinate with vendors and contract manufacturers. Hire, mentor, and develop engineering talent for calibration work.

Design, build, test, and continuously deploy scalable infrastructure and platform tooling. Create technical specs and rollout plans, collaborate with stakeholders, mentor teammates, support services in production, and shape engineering practices across teams.