Top Senior Software Engineer Jobs in Charleston, SC

Senior full‑stack engineer responsible for designing, building, testing, and supporting scalable backend services and user-facing UIs for a healthcare data platform. Works across Agile teams on data ingestion/transformation, APIs, cloud infrastructure, containers, and CI/CD. Leads major initiatives, mentors team members, participates in on-call rotation, and ensures HIPAA/compliance and engineering best practices.

Lead design, development, and maintenance of scalable, cloud-native web applications. Own end-to-end product features, mentor engineers, troubleshoot production incidents, improve performance, implement APIs, and support on-call rotations.

Lead architecture and evolution of Juniper Square’s distributed services, cloud infrastructure, and developer platform. Design scalable, multi-tenant, event-driven systems; build paved-road developer tooling, CI/CD, and observability. Hands-on coding, prototyping, and performance troubleshooting. Enable production AI/LLM workloads, ensure security/compliance, support enterprise upmarket needs, and mentor engineering teams to raise operational excellence and reliability.

Build and deliver end-to-end features across backend APIs (NestJS/TypeScript) and frontend interfaces (React/TypeScript), integrate third-party services, own production services (on-call, monitoring, incident response with Datadog), contribute to architecture, and mentor other engineers. Work across web and React Native mobile apps, and help scale integrations and event-driven systems.

Participate in full SDLC building and integrating software for DoD customers. Develop C++/Python systems, curate synthetic geospatial raster data, apply TDD, operate in DevSecOps pipelines, and use containerization and CI/CD for deployment and testing.

Omada Health seeks a Senior Software Engineer to optimize processes, lead projects, leverage AI/ML, and collaborate cross-functionally to deliver effective healthcare solutions.

The Senior Software Engineer will design and build scalable cloud-native systems, mentor a team, and ensure system security and reliability while driving service ownership.

The Senior Software Full Stack Engineer will design and develop cloud-native applications, ensuring reliability and scalability while collaborating with product engineers and improving coding standards.

As a Senior Software Engineer at Vanta, you will design and build internal tools for go-to-market teams, focusing on applications that enhance sales and customer engagement, employing modern tech and AI workflows.

The Senior Software Engineer will own the development of full-stack features from UI to backend, mentor junior engineers, and drive technical decisions.

The role involves owning feature delivery, designing internal APIs, optimizing performance, mentoring junior engineers, and contributing to incident response.

The role involves developing and integrating AI features into Cribl's products, collaborating with teams, and maintaining operational efficiency.

As a Staff Software Engineer, you'll develop and maintain core platform infrastructure, design scalable systems, mentor junior engineers, and ensure reliability of product features.

The Senior Software Engineer will build user-facing products for clinical AI, improve existing applications, and collaborate with teams to enhance software quality, requiring expertise in multiple technologies and secure coding practices.

Design, build, and maintain APIs and systems at Telnyx, debug production issues, improve engineering standards, and collaborate across teams.

Design and implement high-performance, 3GPP-compliant 5G Core control- and user-plane functions on ARM-based embedded Linux. Develop in C/Go/Rust, use DPDK for packet processing, optimize latency/throughput, debug protocol and performance issues, and collaborate cross-functionally to integrate carrier-grade systems.

Design, build, and operate Planet's scalable object and metadata storage platform. Own backend services, Elasticsearch indexing, search, event notification, and disaster recovery. Measure performance, create alerts, be on call, drive system design and architecture, mentor engineers, and contribute to the technical roadmap for highly available, cloud-native data infrastructure.

Lead technical direction and deliver collision-free motion planning for humanoid robots. Design, implement, test, and deploy trajectory optimization, MPC, and sample-based planners; architect modular planning systems integrated with perception, state estimation, and control; develop algorithms robust to uncertainty; and provide cross-team technical leadership and mentorship.

The Lead Software Engineer is responsible for designing, developing, debugging, and maintaining applications to enhance business workflows, focusing on the architecture, engineering, and construction sectors.

The Staff Software Engineer - Cloud leads the design and implementation of scalable cloud systems and ML pipelines, mentoring a team and collaborating across engineering functions.

The Senior Software Engineer will work on projects involving cloud infrastructure, fare scanner tools, and contactless payment risk management, while collaborating closely with a small engineering team.

The Senior Software Engineer will enhance the Arrive Health Network platform by developing scalable systems, integrating with EHRs, and mentoring team members.

Lead the design and development of full-stack solutions for prescription decision-making, maintain backend systems, mentor engineers, and ensure system scalability.

Design, build, and lead scalable API and platform features. Mentor junior engineers and drive technical initiatives from design to delivery.

The Staff Software Engineer will lead technical initiatives, drive quality code, mentor engineers, and work on scalable systems in a high-impact team environment.