Top Senior Data Science Jobs in Charleston, SC

23 Days AgoSaved
Remote or Hybrid
Charleston, SC
Senior level
Senior level
Software
Lead product experimentation and ML initiatives: design and run A/B tests and causal analyses, build and deploy ML models (GBMs, random forest, logistic regression) using Python and MLflow, partner with Product/Design/Engineering, translate results into executive-facing recommendations, and establish experimentation and ML best practices.
Top Skills: A/B TestingAmplitudeCausal InferenceDatabricksGbmLogistic RegressionMlflowPythonRandom ForestScikit-Learn
23 Days AgoSaved
Remote
Charleston, SC
185K-231K Annually
Senior level
185K-231K Annually
Senior level
Artificial Intelligence • Software • Analytics • Business Intelligence
Lead and build Neural Earth's geospatial data science function: design and deploy Python-based geospatial models, architect production geospatial data pipelines, validate reproducible methods, translate scientific outputs into customer-ready products, and manage and mentor at least one direct report while advising customers and stakeholders.
Top Skills: CogGdalGeopandasGeoparquetGeotiffNetcdfPythonRasterioShapelyXarray
YesterdaySaved
Remote
Charleston, SC
100K-132K Annually
Senior level
100K-132K Annually
Senior level
Healthtech • Social Impact
Build, validate, deploy, monitor, and maintain predictive models and analytical reports. Translate findings for technical and non-technical stakeholders, promote data literacy, deliver training, collaborate on data infrastructure, apply advanced statistical and machine learning methods, and support analytical requests across mental health and crisis care programs.
Top Skills: Amazon RedshiftAmazon SagemakerAWSDeployment PipelinesModel RegistriesPandasPythonRScikit-LearnSnowflakeTidyverseVersion Control
Reposted 23 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Logistics • Software
Senior individual contributor owning complex end-to-end ML problems for supply chain and consumer applications. Build and deploy predictive models (demand forecasting, delivery ETA, recommendations), embed with engineering teams, define MLOps standards, and advise leadership on data science strategy and investments.
Top Skills: Api EndpointsAWSAzureBigQueryDrift DetectionExperimentation FrameworksGCPGitGitMicroservicesModel VersioningPipeline OrchestrationPostgresPythonSQL
Reposted 23 Days AgoSaved
Remote
Charleston, SC
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Partner with Marketing as the embedded data science lead to build marketing measurement, attribution, LTV/ROAS/CAC models, run experiments, analyze the full funnel, create forecasts and dashboards, and influence channel strategy and budget allocation.
Top Skills: Ad PlatformsAppsflyerGoogle AnalyticsLookerMmpPythonRSQLTableau
Reposted 23 Days AgoSaved
Remote
Charleston, SC
255K-298K Annually
Senior level
255K-298K Annually
Senior level
Consumer Web • Other • Social Media • Software
As the Staff Data Scientist, you will lead the data science function, driving strategy, mentoring peers, and shaping product direction through advanced analytics and experimentation.
Top Skills: PythonSQL
Reposted 24 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Big Data • Food • Mobile • Payments
Lead company-level measurement and causal strategy, define MAU×ARPU metrics and semantic mart, set scientific standards for experimentation and analysis, own strategic models (MMM, elasticity, forecasting), partner with engineering to productionize analytics, and raise org-wide scientific maturity through governance, templates, and upskilling.
Top Skills: DbtExperimentation PlatformsPythonSnowflakeSQL
YesterdaySaved
Remote
Charleston, SC
160K-200K Annually
Senior level
160K-200K Annually
Senior level
AdTech • Fintech • Marketing Tech
Build and deploy machine learning and experimentation systems for personalization, ranking, targeting, attribution, and causal measurement. Develop features and pipelines from transaction and behavioral data, design A/B tests, productionize models with engineering teams, and improve recommendation systems. Translate analytical results into business insights tied to conversion, retention, lift, and ROI while owning projects from problem framing through post-launch evaluation.
Top Skills: AirflowAPIsAWSDbtFeature StoresGCPPandasPythonPyTorchScikit-LearnSparkSQLXgboost
Reposted YesterdaySaved
Remote
Charleston, SC
118K-162K Annually
Senior level
118K-162K Annually
Senior level
Healthtech
Design, build, and deploy LLM-based applications and multi-step AI workflows (retrieval, orchestration, agents) using large-scale structured and unstructured data. Partner with engineering to productionize solutions, implement evaluation and safety measures, ensure compliance and data governance, and communicate results to technical and non-technical stakeholders.
Top Skills: SparkAutogenAzureCrewaiDatabricksGCPLangchainLanggraphLlmPythonSnowflakeTransformer-Based Models
Reposted YesterdaySaved
Remote
Charleston, SC
Senior level
Senior level
Biotech • Pharmaceutical
Lead clinical data management across studies: design and oversee eCRF and EDC implementations, coordinate testing and external data integrations, manage data risk assessments, supervise data teams and training, control related budgets, ensure SOP compliance, and drive process improvements.
Top Skills: Datalabs EdcMedidata Rave
Reposted 29 Days AgoSaved
Easy Apply
Remote
Charleston, SC
Easy Apply
180K-212K Annually
Senior level
180K-212K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Own and evolve revenue calibration models tying CX interactions to revenue, design causal inference and experimentation frameworks, build LLM-powered classification/NLP pipelines, productionize models with Analytics Engineers, define segmentation and behavioral signals, and ensure statistical rigor for executive reporting and regulatory defensibility.
Top Skills: A/B TestingCausal InferenceGeminiGenerative AiGleanLibrechatLlmMlNlp
Reposted YesterdaySaved
Remote
Charleston, SC
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead product and program analytics for Microsoft skilling experiences. Design funnel and learner-journey analyses, define success metrics, build measurement frameworks, run experiments and causal analyses, develop competency/skill models, partner with product and engineering on telemetry, recommend content and curriculum improvements, mentor data scientists, and ensure data privacy and telemetry quality.
Top Skills: AdfAdxDatabricksDelta LakeFabricKqlPysparkPythonRSnowflakeSQLSynapse
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One Month AgoSaved
In-Office or Remote
Charleston, SC
124K-165K Annually
Senior level
124K-165K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Design, develop, and deploy production-grade generative AI and agentic systems (LLMs, RAG, AI agents). Build document intelligence, retrieval pipelines, vector search, and monitoring frameworks. Collaborate with risk, compliance, product, and engineering to deliver scalable, governed GenAI solutions in regulated environments.
Top Skills: AirflowAWSAws BedrockAzure AiCi/CdDatabricksEmbeddingsHugging FaceLangchainLanggraphMlflowOcrPrompt EngineeringPysparkPythonPyTorchRetrieval-Augmented Generation (Rag)SagemakerScikit-LearnSnowflakeSnowparkSparkSQLTensorFlowVector DatabasesVllm
Reposted 2 Days AgoSaved
In-Office or Remote
Charleston, SC
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead end-to-end data science for customer-embedded, production solutions: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, run experiments, deploy operational models at scale, coach cross-disciplinary teams, and drive strategy, ethics, and privacy discussions.
3 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Lead end-to-end predictive analytics and machine learning initiatives, including forecasting, churn prediction, and risk modeling. Translate business needs into scalable ML solutions, build and deploy models on AWS SageMaker, develop production ML pipelines, and oversee monitoring, governance, explainability, and retraining. Collaborate with engineering and MLOps teams, communicate insights to stakeholders, and mentor junior data scientists while providing hands-on technical leadership.
Top Skills: Amazon SagemakerApache AirflowAWSAws LambdaAws Step FunctionsCi/CdGenerative AiInfrastructure As CodeKubeflowMlopsNumpyPandasPythonSagemaker PipelinesScikit-LearnXgboost
3 Days AgoSaved
Remote
Charleston, SC
141K-165K Annually
Senior level
141K-165K Annually
Senior level
AdTech
Design and analyze incrementality tests, media mix models, causal analyses, and advanced analytics for marketing measurement. Work with large marketing datasets, assess methodological validity, conduct power and sensitivity analyses, and translate findings into media planning recommendations. Collaborate cross-functionally, improve measurement standards, and mentor junior data scientists.
Top Skills: PymcPythonRSQL
4 Days AgoSaved
Remote
Charleston, SC
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Automotive • Insurance • Software
Own end-to-end data science for a core business area such as growth, product, AI and automation, or strategic partnerships. Define business problems, metrics, reports, analyses, and experiments; generate actionable insights; communicate recommendations; and influence product, growth, finance, and operations leaders to drive measurable outcomes.
Top Skills: ClickhouseGitJupyterhubMetabasePythonSQL
Reposted 26 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Machine Learning • Software
The Staff Data Scientist will lead the development and deployment of ML and GenAI systems to detect billing errors and fraud in healthcare payments, collaborating with cross-functional teams.
Top Skills: AIData ScienceMachine Learning
Reposted 26 Days AgoSaved
Remote
Charleston, SC
220K-290K Annually
Senior level
220K-290K Annually
Senior level
Information Technology • Software
Build and productionize ML models and data infrastructure to analyze millions of chaos engineering experiments, detect and explain failures, recommend automated remediation, and integrate AI-driven failure analysis into Gremlin's product using techniques like causal inference, graph ML, time-series modeling, and reinforcement learning.
Top Skills: Agentic AiCausal InferenceChaos EngineeringData PipelinesFeature StoresGraph MlMlopsModel MonitoringModel ServingReinforcement LearningSite Reliability EngineeringTime-Series Modeling
4 Days AgoSaved
Remote
Charleston, SC
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Financial Services
Own the analytical function for a core business area such as growth, product, AI and automation, or strategic partnerships. Define business questions, metrics, reports, analyses, and experiments; generate insights; and drive data-informed decisions with cross-functional stakeholders. The role requires independently structuring ambiguous problems, using SQL or Python, communicating findings clearly, and delivering measurable business impact.
Top Skills: ClickhouseGitJupyterhubMetabasePythonSQL
4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Big Data • Food • Mobile • Payments
Develop and deploy predictive and causal models for personalization, retention, monetization, and product strategy. Design experimentation and measurement frameworks, analyze user and marketing behavior, quantify business impact, and translate complex findings into strategic decisions. Collaborate with Product, Engineering, Marketing, and Data Product teams to build scalable data solutions. Mentor peers, promote rigorous model validation and governance, and apply Python, SQL, Snowflake, dbt, Airflow, Spark, and AWS to production-ready data science initiatives.
Top Skills: AirflowAWSBayesian InferenceCausal InferenceCcpaDbtExperimentation FrameworksGdprMachine LearningPythonSnowflakeSparkSQL
Reposted 28 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Cloud • Information Technology • Software • Consulting • Web3
Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.
Top Skills: AirflowAWSAzureCi/CdDockerGCPJIRAKubeflowKubernetesMlflowNumpyPandasPlantumlPythonPyTorchSparkTfx
5 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Healthtech
Lead the design, development, deployment, and governance of advanced analytics, machine learning, and AI solutions using large healthcare datasets. Responsibilities include data preparation, statistical and predictive modeling, model monitoring, explainability, visualization, stakeholder communication, and translating findings into clinical and operational improvements. The role also mentors data professionals, advises leaders, manages initiative priorities and risks, and promotes responsible AI and Agile practices.
Top Skills: Advanced AnalyticsAgileArtificial IntelligenceData VisualizationDeep LearningFeature EngineeringGenerative AiMachine LearningNatural Language ProcessingOptimizationPredictive ModelingStatistical Modeling
Reposted 28 Days AgoSaved
Remote
Charleston, SC
194K-253K Annually
Senior level
194K-253K Annually
Senior level
Healthtech
Lead the technical development and automation of enrollment forecasting models, collaborating with various departments to enhance decision-making and forecast accuracy.
Top Skills: NumpyPandasProphetPythonScikit-LearnSQLStatsmodels
29 Days AgoSaved
Remote or Hybrid
Charleston, SC
Senior level
Senior level
Software
Design and deploy ML systems for enterprise search, recommendations, retrieval, and AI agents. Build scalable data/ML pipelines, evaluation frameworks, and metrics. Apply statistics, experimentation, and causal inference to guide product decisions. Collaborate cross-functionally, prototype LLM-based capabilities (embeddings, RAG), and mentor junior team members.
Top Skills: Agent Orchestration FrameworksEmbeddingsFoundation ModelsLlmsPythonRetrieval SystemsRetrieval-Augmented Generation (Rag)SQLVector Databases
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