Top Senior Data Science Jobs in Charleston, SC

18 Days AgoSaved
Remote
Charleston, SC
150K-160K Annually
Senior level
150K-160K Annually
Senior level
Insurance • Pet
Develop and maintain predictive pricing, retention, and conversion models using GLMs and advanced analytics; build monitoring tools for rating performance; support rate filings, product pricing analyses, competitor research, and cross-functional collaboration to inform pricing and enterprise risk decisions.
Top Skills: ClaudeElastic NetExcelGeminiGeneralized Linear Models (Glms)Geospatial StatisticsGithub CopilotK-Means ClusteringPythonRSerffSQL
22 Days AgoSaved
Remote
Charleston, SC
145K-180K Annually
Senior level
145K-180K Annually
Senior level
Healthtech • Telehealth
Senior individual contributor who drives product analytics, experimentation, and applied modeling. Owns growth and performance analyses, designs experiments with robust statistical evaluation, builds repeatable reporting, and partners with Product, Engineering, Operations, Clinical, and Finance to translate data into actionable product and operational decisions.
Top Skills: BigQueryPandasPythonRedshiftScikit-LearnSnowflakeSQLStatsmodels
22 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Agency • Information Technology
Design, build, and deploy machine learning and generative AI models (including LLMs and text-to-image). Analyze large datasets, run A/B and statistical tests, collaborate with data engineering and engineering teams, and create dashboards/visualizations to communicate insights. Optimize data pipelines and model performance to support data-driven decisions.
Top Skills: AWSAzureDall-EGCPGeminiGptLlamaLlmsPower BIPythonPyTorchRScikit-LearnSQLTableauTensorFlow
22 Days AgoSaved
In-Office or Remote
Charleston, SC
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector Databases
22 Days AgoSaved
In-Office or Remote
Charleston, SC
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-ready generative AI applications: architect multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deliver scalable FastAPI-based services with monitoring, CI/CD, and containerized deployment.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
22 Days AgoSaved
In-Office or Remote
Charleston, SC
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted 22 Days AgoSaved
Remote
Charleston, SC
120K-203K Annually
Senior level
120K-203K Annually
Senior level
Healthtech
The Data Scientist II will drive insights, develop models, and analyze product experiments to inform business decisions and improve member experiences in healthcare.
Top Skills: PythonRSQL
23 Days AgoSaved
Remote
Charleston, SC
120K-140K Annually
Senior level
120K-140K Annually
Senior level
Healthtech
Designs, analyzes, and interprets clinical trial, RWE, and observational data for a medical device. Develops statistical plans, predictive models, and ensures data quality, regulatory compliance, and traceability. Collaborates with clinical, regulatory, and data teams, supports submissions and publications, mentors interns, and represents the company externally.
Top Skills: CdiscMl/AiPythonPython DashRR ShinySASSpotfireTableau
36 Minutes AgoSaved
Remote
Charleston, SC
138K-230K Annually
Senior level
138K-230K Annually
Senior level
Financial Services
Lead the intelligence layer atop the data lakehouse: design and run causal experimentation, build predictive and forecasting models, own model evaluation and monitoring, deploy and maintain models on Databricks/MLflow, set technical direction for data science, and partner closely with data engineers, AI engineers, and product. Use AI development tools daily.
Top Skills: AgentsClaude CodeCursorData Vault 2.0DatabricksExperimentation PlatformsGradient BoostingLangfuseLlmsMedallion LakehouseMlflowPythonScikit-LearnSQL
Reposted 16 Hours AgoSaved
In-Office or Remote
Charleston, SC
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead data science strategy across complex customer engagements, turn ambiguous business problems into repeatable ML solutions, define modeling and evaluation standards, drive data readiness and MLOps practices, mentor teams, produce reusable IP, and represent Microsoft in executive and thought-leadership forums.
Top Skills: SparkAzure Machine LearningCi/CdDelta LakeDockerKqlMlflowPythonRRest ApiT-Sql
16 Hours AgoSaved
Remote
Charleston, SC
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Partner with business, finance, and engineering teams to design and evaluate incentive compensation plans. Build scalable data pipelines, ML models, NLP and AI agents, and dashboards to generate actionable insights, perform scenario modeling, and ensure quota and compensation outcomes are explainable, reliable, and aligned to business goals.
Top Skills: AutogenAzure Cognitive ServicesAzure DatabricksAzure Machine LearningAzure SynapseDatabricksJupyter NotebooksLangchainLookerNumpyPandasPower BIPysparkPythonScikit-LearnSemantic KernelSnowflakeTableauVs Code
16 Hours AgoSaved
Remote
Charleston, SC
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead development and deployment of ML and AI solutions for global incentive and quota design. Partner cross-functionally to define quota strategy, build scalable data pipelines and models, create AI agents, evaluate model performance, ensure governance/compliance, and communicate insights to stakeholders to drive business outcomes.
Top Skills: SparkAutogenAzure Cognitive ServicesAzure DatabricksAzure FoundryAzure Machine LearningCi/CdDelta LakeDockerHadoopLangchainMlflowPower BIPythonRest ApiSemantic KernelSQLSsas
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Reposted 17 Hours AgoSaved
Remote
Charleston, SC
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Fintech • Software • Financial Services
The Lead Data Scientist will enhance analytics through predictive modeling and data engineering, focusing on quality, feature generation, and continuous learning.
Top Skills: DashGoogle Data StudioLookerPower BIPythonSQLStreamlitTableau
Reposted 17 Hours AgoSaved
Remote
Charleston, SC
200K-200K Annually
Senior level
200K-200K Annually
Senior level
Fintech
As a Pricing Data Scientist, you'll develop and validate pricing models for alternative assets, collaborate with engineers, and enhance valuation accuracy through data insights.
Top Skills: AWSGCPLightgbmMlflowPandasPythonPyTorchScikit-LearnSQLTensorFlowXgboost
Senior level
Pharmaceutical
Develop and validate SDTM and ADaM datasets using R following CDISC standards, support TLF generation in R/SAS, perform QC and reconcile data issues, collaborate with statisticians and clinical teams, document workflows, and support automation of R-based pipelines for clinical trial deliverables.
Top Skills: AdamCdiscRSASSdtm
Reposted YesterdaySaved
In-Office or Remote
Charleston, SC
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead customer-facing data science engagements: manage data acquisition/cleaning, develop and evaluate scalable models, drive modeling best practices, contribute thought leadership, write extensible code, and define solution and business strategy with cross-functional teams.
Reposted YesterdaySaved
Remote
Charleston, SC
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead data science engagements with customers to acquire, clean, analyze, and model data; develop scalable operational models and evaluation methods; coach engineers on best practices; drive solution strategy, ethics, and industry thought leadership; write extensible code and collaborate across teams to deliver cloud-based AI solutions.
Top Skills: AICloud-Based SolutionsMicrosoft CloudOpen-Source
Reposted 23 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Cloud • Information Technology • Software • Consulting • Web3
Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.
Top Skills: AirflowAWSAzureCi/CdDockerGCPJIRAKubeflowKubernetesMlflowNumpyPandasPlantumlPythonPyTorchSparkTfx
Reposted YesterdaySaved
In-Office or Remote
Charleston, SC
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead customer-facing data science engagements: acquire and prepare data, evaluate and operationalize models at scale, drive modeling best practices, research industry trends, write extensible code, and define solution and customer strategy while promoting ethics and privacy.
Reposted 23 Days AgoSaved
Remote
Charleston, SC
136K-266K Annually
Senior level
136K-266K Annually
Senior level
Big Data • Cloud • Software • Analytics
As a Staff Data Scientist, you will analyze large-scale broadband data, develop and validate ML models, and integrate solutions into Calix Cloud, collaborating with teams for enhanced network intelligence and subscriber experience.
Top Skills: AWSAzureGCPNumpyPandasPythonScikit-LearnScipySQL
YesterdaySaved
Remote
Charleston, SC
63K-127K Annually
Senior level
63K-127K Annually
Senior level
Fintech • Information Technology • Other • Payments
Lead development and deployment of machine learning models, perform EDA and data engineering on large datasets, train models including LLMs and unstructured-data solutions, build Power BI dashboards, automate processes, present findings to leadership, and mentor junior data scientists while working with SQL, Python, AWS/Azure, Snowflake, and Salesforce.
Top Skills: AWSAzureLlmMS OfficeNumpyPandasPower BIPythonSalesforceSnowflakeSQL
24 Days AgoSaved
Remote
Charleston, SC
170K-220K Annually
Senior level
170K-220K Annually
Senior level
Healthtech • Other • Telehealth
Design, implement, and maintain marketing inference models (e.g., MMM and attribution). Analyze large datasets and A/B/uplift experiments with rigorous statistics, build predictive and causal models, partner with marketing to generate testable ideas, and communicate insights to drive marketing decisions.
Top Skills: PythonRSQL
YesterdaySaved
Remote
Charleston, SC
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead end-to-end delivery of strategic data science and AI projects: define business problems with stakeholders, prepare large datasets, build and deploy predictive, prescriptive, and generative AI models (including LLMs), implement prompt engineering and fine-tuning, ensure production-grade code and ML lifecycle practices, present insights to senior stakeholders, and promote responsible AI and adoption across teams.
Top Skills: Agentic AiAzureDevOpsFine-TuningFoundation ModelsGenerative AiLarge Language ModelsPrompt EngineeringPythonSQLVersion Control
YesterdaySaved
Remote
Charleston, SC
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead product and program analytics for Microsoft skilling experiences. Design funnel and learner-journey analyses, define success metrics, build measurement frameworks, run experiments and causal analyses, develop competency/skill models, partner with product and engineering on telemetry, recommend content and curriculum improvements, mentor data scientists, and ensure data privacy and telemetry quality.
Top Skills: AdfAdxDatabricksDelta LakeFabricKqlPysparkPythonRSnowflakeSQLSynapse
YesterdaySaved
In-Office or Remote
Charleston, SC
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead customer-facing data science engagements: manage data acquisition and cleaning, build and evaluate scalable models, drive model best practices and ethics, write extensible code, research industry trends, define solution strategy, and collaborate across engineering and product teams to deliver AI/cloud solutions.
Top Skills: AIAzureCloudMachine LearningOpen-Source
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