Top Senior Data Science Jobs in Charleston, SC

Reposted 24 Days AgoSaved
Remote
Charleston, SC
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Internet of Things
As a Senior Marketing Data Scientist, you will conduct quantitative analyses, manage marketing tests, and provide actionable insights to enhance marketing performance and investment effectiveness.
Top Skills: BigQueryGoogle AdsGoogle AnalyticsLookerMeta Business SuitePythonRedashRedshiftSQL
Reposted 25 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Logistics • Software
Senior individual contributor owning complex end-to-end ML problems for supply chain and consumer applications. Build and deploy predictive models (demand forecasting, delivery ETA, recommendations), embed with engineering teams, define MLOps standards, and advise leadership on data science strategy and investments.
Top Skills: Api EndpointsAWSAzureBigQueryDrift DetectionExperimentation FrameworksGCPGitGitMicroservicesModel VersioningPipeline OrchestrationPostgresPythonSQL
Reposted 25 Days AgoSaved
Remote
Charleston, SC
240K-260K Annually
Senior level
240K-260K Annually
Senior level
Artificial Intelligence • Insurance • Software • Automation
As a Staff Data Scientist, you'll design and optimize ML systems for claims handling automation, collaborating with product and engineering teams.
Top Skills: PythonPyTorchSnowflakeSparkSQLTensorFlowXgboost
Reposted 25 Days AgoSaved
Remote
Charleston, SC
255K-298K Annually
Senior level
255K-298K Annually
Senior level
Consumer Web • Other • Social Media • Software
As the Staff Data Scientist, you will lead the data science function, driving strategy, mentoring peers, and shaping product direction through advanced analytics and experimentation.
Top Skills: PythonSQL
25 Days AgoSaved
Remote
Charleston, SC
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Partner with Marketing as the embedded data science lead to build marketing measurement, attribution, LTV/ROAS/CAC models, run experiments, analyze the full funnel, create forecasts and dashboards, and influence channel strategy and budget allocation.
Top Skills: Ad PlatformsAppsflyerGoogle AnalyticsLookerMmpPythonRSQLTableau
2 Days AgoSaved
Remote
Charleston, SC
125K-135K Annually
Senior level
125K-135K Annually
Senior level
eCommerce • Insurance • Software
Lead cross-functional teams to identify and implement revenue-driving strategies. Own revenue optimization, develop quantitative analyses (A/B testing, causal impact), improve data pipelines and tracking, embed AI into workflows, and present insights to leadership to scale and recover revenue.
Top Skills: A/B TestingClaudeGeminiGitPythonSQL
Reposted 2 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Seeking a Senior Data Scientist to lead predictive analytics and machine learning initiatives. Responsibilities include building ML models, data management, and mentoring junior data scientists. Must have expertise in AWS and strong statistical knowledge.
Top Skills: AirflowAWSKubeflowNumpyPandasPythonSagemakerScikit-LearnStepfunctionsXgboost
2 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Edtech
Lead end-to-end AI/ML initiatives to improve student retention, engagement, and enrollment. Architect and operate data pipelines, feature stores, and production ML systems; deploy, monitor, and automate models; run experimentation programing and measure business outcomes. Mentor team members and set technical standards across Product, Engineering, and CX.
Top Skills: AirflowCi/CdCRMDagsterDatabricksDbtDockerFeature StoresKubernetesLmsMlflowPythonPyTorchScikit-LearnSpeech AnalyticsSQLTensorFlowTerraformXgboost
4 Days AgoSaved
Remote
Charleston, SC
140K-160K Annually
Senior level
140K-160K Annually
Senior level
Biotech
Lead data strategy and analytics for cognitive assessment studies: design algorithms and models, implement CDISC-compliant data transfers (SDTM/ADaM), produce statistical analysis plans and scientific reports, build and maintain analytics pipelines, dashboards, and visualizations, ensure data quality and QC, and present results to sponsors while managing multiple projects independently.
Top Skills: AdamCdiscMachine LearningPysparkPythonRSdtm
4 Days AgoSaved
Remote
Charleston, SC
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Financial Services
Embed in a core business area to define the right problems, design metrics, run analyses and experiments, build reports, surface insights, and drive data-informed decisions end-to-end to improve product, growth, AI/automation, or partnerships.
Top Skills: GitJupyter HubMetabasePythonSql (Clickhouse)
4 Days AgoSaved
Remote
Charleston, SC
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Artificial Intelligence • Automotive • Insurance • Software
Embed within a core business area to define problems, build metrics and analyses, run experiments, generate insights from data, and drive decisions end-to-end to improve product, growth, AI/automation, or partnerships.
Top Skills: ClickhouseGitJupyter HubMetabasePythonSQL
Reposted 4 Days AgoSaved
Remote or Hybrid
Charleston, SC
150K-185K Annually
Senior level
150K-185K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
The Senior Data Scientist will develop machine learning systems for fraud prevention using behavioral data, collaborate across teams, and mentor junior scientists.
Top Skills: PysparkPythonScikit-LearnSparkSQLTensorFlowXgboost
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Reposted 5 Days AgoSaved
Remote or Hybrid
Charleston, SC
140K-180K Annually
Senior level
140K-180K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning • Analytics • Business Intelligence • Consulting • Generative AI
Design, build, and deploy ML models across diverse use cases; work with managed cloud ML platforms and containerized solutions; collaborate with engineers on production integration and MLOps best practices; preprocess and analyze large datasets; mentor teammates and influence technical direction; translate complex ML concepts for technical and non-technical stakeholders.
Top Skills: AWSAzure MlC++DockerEc2FivetranGitMatillionPyramid AnalyticsPythonRSagemakerSnowflakeSQLVertex Ai
Reposted 5 Days AgoSaved
Remote or Hybrid
Charleston, SC
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning • Analytics • Business Intelligence • Consulting • Generative AI
Lead end-to-end client ML engagements: scope problems, design, build, and deploy production ML solutions across cloud and containerized stacks. Lead and mentor small teams, manage client relationships, evaluate emerging tools, and ensure models are production-ready and explainable to technical and non-technical stakeholders.
Top Skills: AWSAzure MlDockerEc2FivetranGitHugging FaceMatillionMlflowPyramid AnalyticsPythonPyTorchSagemakerScikit-LearnSnowflakeSQLVertex AiWeights & Biases
Reposted 5 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Consumer Web • Software • Business Intelligence
The Senior Data Scientist will develop scalable ML models, analyze large datasets for insights, and collaborate with teams to enhance business performance through data-driven solutions.
Top Skills: HadoopMachine LearningNumpyPandasPythonRScipySpark
Reposted 5 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
Design, develop, and deploy causal inference and predictive models (uplift, synthetic control, DML) for customer loyalty, churn, and LTV. Build foundational data models and scalable features, perform large-scale SQL ETL, operationalize models in cloud, partner with stakeholders, and present insights to drive revenue and loyalty program optimization.
Top Skills: CausalmlCloud EnvironmentsDowhyEconmlMachine LearningNumpyPandasPythonScikit-LearnSQL
Reposted 5 Days AgoSaved
Remote
Charleston, SC
140-150 Annually
Senior level
140-150 Annually
Senior level
Real Estate • Travel • PropTech
The role involves building and validating Marketing Mix Models and geo-experiments, managing measurement infrastructure, and communicating insights to stakeholders.
Top Skills: PythonRSQL
Reposted 6 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
Design, develop, and deploy time-series and machine-learning forecasting models (ARIMA, SARIMA, ETS, XGBoost, LightGBM) for demand planning, inventory, and sales forecasting. Perform large-scale SQL data processing, operationalize models in cloud environments (Azure preferred), present insights, and lead client workshops.
Top Skills: ArimaAzureCloudEtsGbmLightgbmNumpyPandasPythonRandom ForestSarimaScikit-LearnSQLStatsmodelsXgboost
Reposted 6 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Generative AI
As a Lead Data Scientist, you'll design experiments, build predictive models, and lead a team while shaping data-driven strategies to enhance AI deployments.
Top Skills: AirflowBigQueryDbtGitLookerPythonSQL
7 Days AgoSaved
Remote
Charleston, SC
97K-124K Annually
Senior level
97K-124K Annually
Senior level
Cloud • Healthtech • Information Technology • Software • Consulting
Design and build predictive models, AI tools, and data visualizations for CMS healthcare initiatives. Analyze quantitative and qualitative data (Medicare claims, public datasets, web analytics), perform feature engineering, anomaly detection, and provide insights to support product design and price-transparency tools. Collaborate with designers, product owners, and engineers in an agile environment.
Top Skills: Decision ForestsK-NnMatlabNaive BayesNumpyPysparkPythonRSparklyrSvmTensorFlowWeka
Reposted 7 Days AgoSaved
Remote
Charleston, SC
177K-230K Annually
Senior level
177K-230K Annually
Senior level
Healthtech • Software
As a Senior Data Scientist, you'll lead projects leveraging data to enhance healthcare outcomes, mentor team members, and align data efforts with business goals.
Top Skills: Machine Learning ToolsPythonSQLStatistical Packages
8 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Healthtech
Senior individual contributor who builds statistical models and experiments to optimize acquisition, conversion, retention, and lifetime value. Partners with Product, Marketing, and Engineering to define data requirements, analyze A/B tests, perform cohort and funnel analyses, communicate findings to stakeholders, and mentor junior team members while contributing to analytics best practices.
Top Skills: AWSAzureGCPGitPythonSQL
Reposted 8 Days AgoSaved
Remote
Charleston, SC
165K-206K Annually
Senior level
165K-206K Annually
Senior level
Other
Build and maintain large commercial datasets and predictive/forecasting models (BigQuery, dbt, SQL, Python). Design causal and experimental analyses to measure promotion impact and price elasticity. Partner with commercial, finance, and executive stakeholders to inform pricing, distribution, and investment. Deploy LLMs and AI agents to classify unstructured data and build tools that democratize data access.
Top Skills: Ai AgentsBigQueryDbtLlmsPandasPythonSQL
Reposted 8 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Healthtech • Software • Database • Biotech • Pharmaceutical
As a Senior Data Scientist, you will develop statistical models and machine learning algorithms to improve patient enrollment and trial management while ensuring compliance in a healthcare data environment.
Top Skills: Aws AthenaAws RedshiftAws SagemakerDbtPythonSQL
Reposted 8 Days AgoSaved
Remote or Hybrid
Charleston, SC
170K-200K Annually
Senior level
170K-200K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
As a Senior Data Scientist, you will design and deploy machine learning and graph algorithms to enhance identity trust solutions, own end-to-end projects, and collaborate with product and engineering teams to improve KYC and compliance products.
Top Skills: AirflowAWSAws NeptuneDatabricksDglGraphframesNeo4JPysparkPythonPyTorchPytorch GeometricScalaScikit-LearnSparkSQLTensorFlowXgboost
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