Top Illinois Artificial Intelligence Startups (144)

Prolaio is a clinical intelligence company dedicated to unlocking continuous, predictive and shareable heart data to liberate patients from hospital-based reactive care and accelerate every new therapy. The company was created by cardiologists, cardiovascular practitioners, and data scientists specifically to address the world’s number one cause of death — cardiovascular disease. By combining scientific rigor with cutting‑edge technology, Prolaio aims...

Caxy is a Chicago based software consulting and custom software development agency founded in 1999. Ranked top 3 software companies in Chicago by Clutch. Our secret sauce is that we want to make life as a developer fun, rewarding and not a grind. We have a commitment we call "The Caxy Promise." Many jobs in software are characterized by clients...

It’s an exciting time to be a Teragonian! Come help us transform the Private Equity industry and drive AI innovation while taking on new challenges and career growth opportunity.​ Teragonia provides an AI-based Value Orchestration platform for private equity backed mid-market operators, helping them transform fragmented operational data into an execution-focused view of business performance. With Teragonia, mid-market leaders align their...

Who We Are Founded in 2001, Adage Technologies is a digital engineering firm building modern, AI‑enabled solutions that help organizations engage their audiences and operate more efficiently. With offices in Chicago and Medellín, our 120‑person team blends strategy, design, engineering, and data to create impactful digital experiences for performing arts organizations, associations and accreditation bodies, and manufacturing and distribution companies. What We...

Bectran is an industry-leading SaaS platform which has grown rapidly to become the companion toolkit for the Credit Department just as a CRM is for the Sales Department. Recognized as a top innovator in the credit software industry, Bectran has been described by credit professionals as "the future of the credit department."​

Recognized by Crain’s as one of 2025’s Most Innovative Companies, UncommonX helps customers move from reactive defense to proactive resilience, with the context, prioritization, and insights needed to reduce risk and respond with precision. We believe cybersecurity should deliver more than alerts — it should deliver clarity, confidence, and control. That’s why we built an AI-powered Exposure Management platform that gives...

Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...

At Quantum Rise, we're transforming how businesses use AI and automation to fuel growth and innovation. As an AI-native company, we combine human expertise with cutting-edge technology to solve real-world challenges. Our team is passionate about building products that are always on, continuously improving, and designed to help companies get the most out of their existing technology. But it’s not...

Flatfile, the pioneer of AI-assisted data exchange, provides companies and their software development teams with the easiest, fastest, and safest way to build the ideal data file import experience for their users. Hundreds of companies such as AstraZeneca, Square or Sage rely on Flatfile’s extensible, API-first platform to create enterprise-scale, intelligent, file-based data import solutions, increase developer productivity, reduce cost...

Prosodica transforms the way organizations understand and improve human connection. Our AI-powered conversation analytics platform captures every nuance of human dialogue—tone, pacing, empathy, and engagement—and translates it into measurable data that leaders can act on. By quantifying what was once intangible, Prosodica helps enterprises build stronger teams, elevate customer experiences, and create workplaces where communication drives results. At the heart of...

DeepWalk has built an AI-driven platform that measures 3D models of infrastructure and creates useful deliverables for engineering, planning, and maintenance teams. Over 100 cities across America rely on DeepWalk’s software for measuring, planning, and updating infrastructure, starting with sidewalks. Creating 3D models of buildings and infrastructure has become affordable and widespread. However, extracting useful information from models is extremely challenging....

Vidmob is the creative data company. Its AI-based software improves creative and media performance by helping brands and agencies derive their own custom creative best practices, and ensure that those learnings are applied across all flighted media. Vidmob’s approach to using creative data drives brand consistency, reduces creative and media waste, and increases overall business performance across the funnel. As...

Benmore Technologies is a Chicago-based software consulting and development firm that partners with founders, startups, and SMBs to design, build, and launch custom software products. We specialize in zero-to-one development, helping clients go from idea to MVP through a structured discovery process, clear technical architecture, and hands-on implementation. Our team works across web, mobile, AI/LLM, and cloud systems, using modern stacks...

Motion’s mission is to empower everyone to do their best work by automatically optimizing their schedule. By constantly monitoring and reorganizing people's to-do list and calendar, we help professionals make time for their highest priority tasks, reduce the stress of being overwhelmed by meetings, and make sure deadlines are never missed.

Performance AI builds the adaptable AI backbone that seamlessly integrates with the tools people already use—Excel, Slack, email, and core systems—to transform messy data into real-time decisions and actions. Our Stack & Scale platform connects disparate data sources, runs industry-tuned AI agents in the background, and delivers governed, guideline-aligned outputs within the workflow.

Cognitiv is a deep learning advertising company redefining how brands connect with consumers. Since 2015, we have built a custom AI platform that predicts consumer behavior in real time and drives performance at scale. Advertisers can activate through their preferred DSP, our managed service DSP, or our industry-first ContextGPT product. By combining advanced data science with flexible activation, we deliver...

Convr is the leading Artificial Intelligence (AI) company that is digitally transforming commercial P&C underwriting. Convr’s d3 Underwriting™ solution uses data discovery and decision science to empower commercial carriers to achieve underwriting and operational excellence through digitizes submission paperwork, such as ACORD applications and loss runs reducing manual data entry, provides insights on risks from thousands of data sources, uses machine...

Proper is transforming the multifamily property management industry through a nationwide rollup model—leveraging AI, process innovation, and a strong focus on employee and resident experience. We streamline building and back-office operations, drive higher NOI for property owners, and elevate the end-to-end experience for building owners, employees and residents alike. With multiple completed transactions and more in the pipeline, Proper acquires...

We empower patients with secure custody and control of their health data and simplify navigating care. We connect patients with rare and chronic conditions to non-profit communities for support and they can opt-in to sharing confidential insights for research and development, and receive compensation for their contributions. Our healthcare ecosystem is where patients are active participants, care is personalized and...

Focused is a software services company that builds agentic AI and custom software. Our expert engineers and designers build custom agents that integrate seamlessly with the systems you already run. What sets Focused apart is our hands-on, collaborative approach. We don’t just build and deliver software, we partner with your teams to ensure that we are building the right solution...