Top Illinois Artificial Intelligence Startups (195)
Caxy is a Chicago-based custom software and AI consultancy that has been building production software since 1999. We’re an AWS Advanced Partner, and our senior engineers work across gaming, fintech, manufacturing, hospitality, and healthcare, taking projects from prototype to production without offshore handoffs. We’ve stuck around this long by treating people well. The Caxy Promise means clear expectations, protected focus time,...
Prolaio is a clinical intelligence company dedicated to unlocking continuous, predictive and shareable heart data to liberate patients from hospital-based reactive care and accelerate every new therapy. The company was created by cardiologists, cardiovascular practitioners, and data scientists specifically to address the world’s number one cause of death — cardiovascular disease. By combining scientific rigor with cutting‑edge technology, Prolaio aims...
Bectran is an industry-leading SaaS platform which has grown rapidly to become the companion toolkit for the Credit Department just as a CRM is for the Sales Department. Recognized as a top innovator in the credit software industry, Bectran has been described by credit professionals as "the future of the credit department."
It’s an exciting time to be a Teragonian! Come help us transform the Private Equity industry and drive AI innovation while taking on new challenges and career growth opportunity. Teragonia provides an AI-based Value Orchestration platform for private equity backed mid-market operators, helping them transform fragmented operational data into an execution-focused view of business performance. With Teragonia, mid-market leaders align their...
At Quantum Rise, we're transforming how businesses use AI, Data, and Automation to fuel growth and innovation. As an AI-native company, we combine human expertise with cutting-edge technology to solve real-world challenges. Our team is passionate about building products that are always on, continuously improving, and designed to help companies get the most out of their existing technology.
Prosodica transforms the way organizations understand and improve human connection. Our AI-powered conversation analytics platform captures every nuance of human dialogue—tone, pacing, empathy, and engagement—and translates it into measurable data that leaders can act on. By quantifying what was once intangible, Prosodica helps enterprises build stronger teams, elevate customer experiences, and create workplaces where communication drives results. At the heart of...
Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...
Flatfile, the pioneer of AI-assisted data exchange, provides companies and their software development teams with the easiest, fastest, and safest way to build the ideal data file import experience for their users. Hundreds of companies such as AstraZeneca, Square or Sage rely on Flatfile’s extensible, API-first platform to create enterprise-scale, intelligent, file-based data import solutions, increase developer productivity, reduce cost...
Who We Are Founded in 2001, Adage Technologies is a digital engineering firm building modern, AI‑enabled solutions that help organizations engage their audiences and operate more efficiently. With offices in Chicago and Medellín, our 120‑person team blends strategy, design, engineering, and data to create impactful digital experiences for performing arts organizations, associations and accreditation bodies, and manufacturing and distribution companies. What We...
Through our embedded lending infrastructure, we enable platforms to offer capital to their customers in Latin America. R2 has partnered with some of the region's most iconic companies, including Rappi and Clip, to power their capital arms. We are backed by Gradient Ventures (Google's AI-focused fund), General Catalyst, Y Combinator, 166 2nd, Soma Capital, Femsa Ventures, PayU, and other global investors.
You rely on technology every day, but is it really working for you? Maybe it feels like IT is just one more thing holding your business back. You’ve dealt with recurring issues, sluggish support, missed opportunities, and rising security risks. You’ve invested time and money, but it’s not translating into real progress—or a competitive advantage. You want more than a vendor. You want a...
Moonlite is building a cloud-native experience on-prem. Our software provides the control and customization enterprises need for AI. Build Faster with Moonlite Instantly download and deploy NIMS from NVIDIA or build your own applications with Hugging Face. Customize and deploy AI agents in one click or integrate your own with ease. Total Control Over Your AI Obtain the highest level of security by design...
FleetPulse™ is the leading trailer telematics company that enables end-to-end visibility into trailer safety and cargo security, serving customers with OEM-agnostic wired and aftermarket telematics offerings. Based in Chicago, Illinois, FleetPulse combines deep roots in the trucking industry with expert tech talent and offers telematics solutions across a comprehensive portfolio of devices, from hard-wired, OEM-installed sensors to easy-to-install aftermarket sensors and...
Andromeda Cluster was founded by Nat Friedman and Daniel Gross to give early-stage startups access to the kind of scaled AI infrastructure once reserved only for hyperscalers. We began with a single managed cluster — but it filled almost instantly. Since then, we’ve been quietly building the systems, network, and orchestration layer that makes the world’s AI infrastructure more accessible. Today, Andromeda...
Ultra Tendency is an international Data & AI consultancy that helps organizations design, build, and operate large-scale, data-driven platforms. Its expertise spans data engineering, big data, cloud, streaming, industrial IoT, microservices, analytics, AI, and generative AI. The company works with enterprise customers across Europe and contributes to open-source projects including Apache Kafka, Apache NiFi, Terraform, and Ansible, and other technologies.
We believe in the power of technology to create sustained, differentiated advantage. Our firm helps organizational leaders understand and use emerging digital solutions to drive value across their business. Technology has become an accelerating source of competitive divergence – Cuesta helps companies capitalize on this opportunity with a pragmatic, hands-on approach. Our team has scaled and operated companies across several industries,...
Wi‑Tronix is the digital platform the rail industry turns to for real‑time IoT data, AI‑powered analytics, and intelligent video. This is not a typical SaaS environment, and it is not a research lab. Our work is connected to critical infrastructure, our 2026 AI roadmap is funded and shared across the company, and quality is a standard we hold each other...
We empower patients with secure custody and control of their health data and simplify navigating care. We connect patients with rare and chronic conditions to non-profit communities for support and they can opt-in to sharing confidential insights for research and development, and receive compensation for their contributions. Our healthcare ecosystem is where patients are active participants, care is personalized and...
Focused is a software services company that builds agentic AI and custom software. Our expert engineers and designers build custom agents that integrate seamlessly with the systems you already run. What sets Focused apart is our hands-on, collaborative approach. We don’t just build and deliver software, we partner with your teams to ensure that we are building the right solution...




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