Top Illinois Artificial Intelligence Startups (167)

Bectran is an industry-leading SaaS platform which has grown rapidly to become the companion toolkit for the Credit Department just as a CRM is for the Sales Department. Recognized as a top innovator in the credit software industry, Bectran has been described by credit professionals as "the future of the credit department."​

At Quantum Rise, we're transforming how businesses use AI and automation to fuel growth and innovation. As an AI-native company, we combine human expertise with cutting-edge technology to solve real-world challenges. Our team is passionate about building products that are always on, continuously improving, and designed to help companies get the most out of their existing technology. But it’s not...

Caxy is a Chicago based software consulting and custom software development agency founded in 1999. Ranked top 3 software companies in Chicago by Clutch. Our secret sauce is that we want to make life as a developer fun, rewarding and not a grind. We have a commitment we call "The Caxy Promise." Many jobs in software are characterized by clients...

Prolaio is a clinical intelligence company dedicated to unlocking continuous, predictive and shareable heart data to liberate patients from hospital-based reactive care and accelerate every new therapy. The company was created by cardiologists, cardiovascular practitioners, and data scientists specifically to address the world’s number one cause of death — cardiovascular disease. By combining scientific rigor with cutting‑edge technology, Prolaio aims...

It’s an exciting time to be a Teragonian! Come help us transform the Private Equity industry and drive AI innovation while taking on new challenges and career growth opportunity.​ Teragonia provides an AI-based Value Orchestration platform for private equity backed mid-market operators, helping them transform fragmented operational data into an execution-focused view of business performance. With Teragonia, mid-market leaders align their...

Prosodica transforms the way organizations understand and improve human connection. Our AI-powered conversation analytics platform captures every nuance of human dialogue—tone, pacing, empathy, and engagement—and translates it into measurable data that leaders can act on. By quantifying what was once intangible, Prosodica helps enterprises build stronger teams, elevate customer experiences, and create workplaces where communication drives results. At the heart of...

Flatfile, the pioneer of AI-assisted data exchange, provides companies and their software development teams with the easiest, fastest, and safest way to build the ideal data file import experience for their users. Hundreds of companies such as AstraZeneca, Square or Sage rely on Flatfile’s extensible, API-first platform to create enterprise-scale, intelligent, file-based data import solutions, increase developer productivity, reduce cost...

Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...

Who We Are Founded in 2001, Adage Technologies is a digital engineering firm building modern, AI‑enabled solutions that help organizations engage their audiences and operate more efficiently. With offices in Chicago and Medellín, our 120‑person team blends strategy, design, engineering, and data to create impactful digital experiences for performing arts organizations, associations and accreditation bodies, and manufacturing and distribution companies. What We...

OneSix is a leading data and artificial intelligence consultancy that helps businesses build the strategy, technology, and teams they need to innovate and grow. We excel at solving complex problems through integrated teams of strategists, data engineers, data scientists, and AI and machine learning experts.

Precision’s goal is to provide breakthrough treatments for the one billion patients worldwide suffering from neurological illnesses. We are building the only brain–computer interface that is designed to be minimally invasive, safely removable, and capable of processing large amounts of data. To learn more about how Precision is connecting human intelligence and artificial intelligence, visit www.precisionneuro.io.

Turnkey provides secure, scalable, and programmable crypto infrastructure for embedded wallets and onchain transaction automation. Designed by the team that scaled Coinbase Custody past $100B in assets, and backed by Sequoia, Bain Crypto Capital, Lightspeed Faction, Galaxy, and Coinbase Ventures, Turnkey provides low-level wallet infrastructure primitives that can be mixed, matched, and configured for any use case. Trusted by Moonshot, Alchemy,...

Citrine Informatics is the award-winning materials informatics platform for data-driven materials and chemicals development. It won the 2017 World Materials Forum Start-up Challenge, the 2018 AI Breakthrough award as the "Best AI-based Solution for Manufacturing," and 2020-2021 Cleantech 100 honors. The Citrine Platform combines smart materials data infrastructure and AI, which accelerates development of cutting-edge materials, facilitates product portfolio optimization,...

We train AI agents for Businesses across LATAM. In less than 1 week you can have a Sales or Support agent in WhatsApp or other channels! Darwin is the best AI agent for any Consultative Sales business from the following industries: Real Estate, Automotive, Education, Retail, and Services. With the guidance of our onboarding executives, you can quickly train & configure Darwin...

TradingBlock was recently named the 2025 Best Brokerage for Options Trading by Benzinga based on our commitment to providing investors, active traders, and investment professionals intuitive, fully customizable brokerage and trading solutions.

Qumis is generative AI built for the hardest part of insurance: understanding the policy. Built by attorneys. Made for scale. Used by the people who make insurance work.

MSPbots is the market leader in proactive intelligence solutions for MSPs. Providing customized BI widgets, dashboards, and innovative apps to streamline daily responsibilities. With our solutions, we generate trackable metrics, send instant messages with issue explanations and resolution steps, and escalate recurring issues to managers for immediate action. MSPbots is dedicated to providing data-driven process automation to enable the growth...

Castalia Systems offers biometric, open source, all source, and signals for intelligence analysis in Florida.

seoClarity is the enterprise search intelligence platform that merges SEO and AI search optimization to keep global brands visible. Our platform pinpoints specific visibility gaps where your brand is currently excluded from AI synthesis and long-tail discovery. With a proven history of helping 3,500 brands like Zillow, Expedia, and Samsung dominate visibility, this is where true search intelligence lives. The way...

Moonlite is building a cloud-native experience on-prem. Our software provides the control and customization enterprises need for AI. Build Faster with Moonlite Instantly download and deploy NIMS from NVIDIA or build your own applications with Hugging Face. Customize and deploy AI agents in one click or integrate your own with ease. Total Control Over Your AI Obtain the highest level of security by design...