Top Palo Alto, CA Software Startups (921)

American medicine is the best in the world. But the American healthcare system is challenged by high administrative costs that burden patients, health systems, and insurance companies with unnecessary expenses. We are focused on addressing those challenges. We use GenAI to improve the most pressing financial pain points in the revenue cycle. We’re one of the first companies to deploy GenAI...

Our mission is to remove inefficiency from the foundation of AI. By combining new research in information theory, probabilistic modeling, and distributed systems, we’re creating self-optimizing data infrastructure that continuously improves how information is represented and used by intelligent systems.

Rundoo is the AI-native, all-in-one ERP for independent supply stores: point of sale, inventory, payments, and the general ledger in one system. We serve independent paint, hardware, and farm & feed retailers who've been stuck running their business on outdated point-of-sale systems and a patchwork of disconnected software, and we're built to help them modernize: better experiences for them, their...

As the trusted choice for digital agencies, SaaS platforms, and web professionals, Duda powers over 1 million websites worldwide. Our platform offers a comprehensive suite of tools that enable users to efficiently create pixel-perfect, feature-rich websites at scale.

Eve Legal is pioneering the future of legal technology by focusing on AI-driven solutions that empower plaintiff-side law firms. With a robust platform designed for efficiency and effectiveness, Eve leverages artificial intelligence to streamline case analysis, enhance decision-making, and optimize client outcomes. Our mission centers on providing attorneys with the tools needed to stay competitive and navigate the legal landscape...

Drive employee experience and engagement programs in new and meaningful ways with Espresa’s leading product, global Lifestyle Spending Accounts (LSA). And, with LSA+, you have even more ways to power inclusive flexibility with integrated total wellbeing, recognition, and community. Give your employees freedom of choice while using the HR tech engine that supports People Teams with attraction and retention, minimal...

Frontier Energy is a professional services firm that excels in market transformation. With a team of 170 talented people in eight offices across the U.S., Frontier Energy has decades of experience in program management, engineering, software, and customer engagement. We are committed to a single mission: To provide exceptional programs, services, and tools that encourage the intelligent use of energy. We...

CXApp is now CXAI – an Enterprise Workplace Experience Platform that leverages cutting-edge AI technology to help Global 2000 enterprises adjust to the evolving workplace requirements, create an engaging and productive work environment, and optimize office space utilization. With the CXAI platform, you can design a personalized experience for thousands of employees. It connects all their daily work tools and...

Luminary Cloud is an early-stage tech startup focused on innovations in high-performance computing for enterprise industrial R&D. The company is currently developing its initial product in stealth mode.

Fireworks.ai offers generative AI platform as a service. We optimize for rapid product iteration building on top of gen AI as well as minimizing cost to serve. https://fireworks.ai/careers

From custom silicon to intelligent algorithms, we’re breaking through the bottlenecks holding AI back, delivering orders-of-magnitude more performance, anywhere it’s needed. Persimmons, Inc. is on a mission to redefine what’s possible in AI inference computing. We design breakthrough full-stack solutions. From custom silicon to cutting-edge algorithms that shatter today’s performance limits and unlock AI’s true potential. Our next-generation inference platform delivers orders-of-magnitude...

85% of AI pilots die in PowerPoint. Digica exists for the other 15%, where algorithms meet atoms and theory meets Thursday’s target. We build AI forged in production, proven under pressure, deployed where failure costs lives and livelihoods. What makes us different: We don't transform operations - we fortify them. We don't replace your workforce - we amplify them. While others promise...

Enterprise transformations shouldn't take years or cost fortunes. At Tessera, we've built a multi-agent AI platform that cuts ERP transformation timelines from years to weeks and reduces costs by more than half—while delivering first-time-right outcomes with enterprise-grade security and governance. We combine the dependability of a trusted integrator with the speed of an AI innovator. Our vendor-agnostic platform is pre-trained on...

Upbound is the industry’s first platform for building internal cloud platforms. Designed around control planes, Upbound offers a new methodology for building an internal cloud platform, purpose-built for your organization. Customers can build, deploy, manage, secure, and use their platforms all from a single point of control. Upbound is designed for enterprise, ensuring performance, multi-tenancy and security. Built on the...

Prysm Health is a fully funded, early stage healthcare technology company building a SaaS platform to assist post-acute care operators and help improve care for millions of patients across the US. We have strong institutional backing, a built-in customer base, and a founding team with deep expertise across healthcare operations, clinical care, and software engineering.

Drivetrain is a financial planning & decision-making platform that helps businesses scale and achieve their targets predictably.

We are building the trust and governance infrastructure for the internet. Data protection and trust go beyond borders, beyond organizations, and beyond individual teams. Believing that the global data protection and privacy environments have been far more complex than they should be, Relyance is reimagining what data protection means in a globalized, technology-driven world. Relyance is shifting the entire landscape of...

GridCARE is the essential one-stop power solution for AI data centers, delivering energy security and resilience at unprecedented speed. The company's AI-powered proprietary platform identifies and unlocks previously untapped grid capacity to accelerate AI infrastructure deployment. By creating the critical bridge between power availability and AI expansion, GridCARE is enabling the next generation of AI innovation.

Blockstream’s mission is to create the financial infrastructure of the future. We build crypto-financial infrastructure based on Bitcoin, the most robust and secure blockchain. Applying cutting-edge cryptography and security engineering, we’re building the products and networks that make financial markets more efficient by reducing reliance on trust. With a long term outlook on delivering robust and scalable solutions, we invest...

ZutaCore’s waterless, direct-to-chip liquid cooling, with its exclusive pool boiling technology, represents a fundamental shift from traditional air or single-phase liquid cooling. Instead of moving heat away gradually, it removes it instantly at the source by turning liquid into vapor, keeping processors consistently cool even under the most extreme workloads. For operators, the impact is immediate: Higher performance per rack — Run...