Top Senior IT Jobs in Wilmington, NC

Oversee and finalize legal documents governing data sharing between Healthcare Fraud Prevention Partnership members and a trusted third party. Collaborate with CMS, HFPP leadership, partner engagement teams, and private payer partners on agreements, compliance, and negotiations. Present to management, support partner relationships, and ensure legal requirements are met for data governance and sharing.

Lead administration of Microsoft 365, Google Workspace, SaaS applications, Azure identity, and cloud infrastructure in a fully cloud-based organization. Provide Level 2/3 service desk escalation, execute migrations and cybersecurity projects, establish IT service processes, manage assets and vendors, and support onboarding, offboarding, incident response, change management, and M&A initiatives. The role partners with IT leadership and may help build and manage a growing internal technical team.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

Lead human-centered design and front-end engineering for the NIH Data Lakehouse: conduct user research and testing; create wireframes, prototypes, flows, and accessible interfaces; build scalable React/Next.js/TypeScript UI components; integrate with GraphQL and search services; contribute to design systems, component libraries, and platform-wide front-end best practices.

Leads enterprise architecture for Biogen’s Veeva ecosystem across Development, Quality, Regulatory, Safety, and Commercial functions. Translates business needs into scalable Veeva configurations and integrations, governs target-state architecture and platform standards, reviews solution designs, and oversees implementation and release planning. Mentors configuration teams, drives cross-vault consistency, manages architecture governance, aligns with Veeva product roadmaps, and advises IT leadership on platform strategy, investments, regulatory compliance, and business objectives.

Leads the design, development, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system architecture blueprints, selects technologies, integrates distributed systems across on-premise and cloud environments, optimizes performance, ensures compliance with DoD requirements, and leads engineering teams. Diagnoses system issues, implements solutions, and produces architecture documentation while supporting installation, migration, and configuration activities across multiple client locations.

Leads the architecture, design, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system blueprints, selects technologies, integrates distributed systems across on-premises, cloud, and hybrid environments, optimizes performance, resolves system issues, and ensures compliance with DoD requirements. Leads engineering teams, supports installation and migration at multiple locations, and documents architecture and implementation decisions.

Owns and leads Regulatory IT systems supporting Global Regulatory Affairs and R&D. Responsibilities include maintaining technology roadmaps, managing system enhancements and implementations, overseeing vendors and releases, providing production support, delivering integrations, conducting data mapping and validation, and ensuring GxP, HIPAA, GDPR, and CCPA compliance. The role serves as the primary IT partner for regulatory business units, manages budgets, and coordinates cross-functional teams delivering regulated technology initiatives.

Leads complex federal platform, cloud infrastructure, IT services, security, compliance, and disaster recovery initiatives. Coordinates AWS GovCloud infrastructure-as-code, deployment automation, observability, Zero Trust identity programs, FedRAMP High and DoD IL5 readiness, and operational resilience. Partners across Engineering, Security, Compliance, and Product to manage roadmaps, dependencies, risks, milestones, and audit readiness. The role also builds and mentors a Federal Platform Operations team and drives reliable, repeatable delivery practices.

Designs and maintains automated testing frameworks, scripts, datasets, and tools for complex data-driven software. Develops test plans, performs exploratory, database, API, performance, and integration testing, and validates data accuracy across systems. Analyzes defects and test metrics, supports CI/CD pipeline integration, and collaborates with application teams to resolve issues. The role also uses Playwright, database scripting, cloud technologies, Agile practices, and generative AI tools to improve software quality and efficiency.

Senior Cybersecurity Engineer to engineer and manage Tenable, Splunk, McAfee and other security tools; perform risk assessments, incident triage and coordination, system hardening, security posture assessments, develop security toolsets, and maintain awareness of threats and vulnerabilities in support of Department of State missions.

Designs and delivers secure, scalable cloud solutions across AWS and Azure for application, data, scientific, and research workloads. Partners with customers to translate requirements into architectures, develops Terraform infrastructure and automation, integrates DevOps and CI/CD capabilities, and manages solutions through implementation and transition to operations. Responsibilities include cloud networking, identity, security, monitoring, backup and recovery, troubleshooting, documentation, technical reviews, and collaboration within an Agile Cloud DevOps team.

Leads functional and automated testing for complex modern, cloud-based applications. Develops test strategies, plans, cases, and automation for unit, API, integration, UI, performance, security, and regression testing. Validates Kafka-based workflows, microservices, serverless systems, data pipelines, and CI/CD releases. Partners with engineering and DevSecOps teams on defect prevention, security, observability, environment readiness, root-cause analysis, and operational quality. Maintains audit-ready documentation and communicates risks and recommendations to stakeholders.

Design and lead development of instructor-led, virtual, and hybrid software training. Collaborate with SMEs and agencies to create ADDIE-based curricula, ensure Section 508 compliance, produce webinars, web-based training, user guides and online help, and evaluate training effectiveness for USPS implementations.

Act as the technical lead for field sales, manage evaluations, deliver on-site and remote demos, prepare SOWs/RFIs/RFPs, respond to security questionnaires, train sales teams, and support sales across U.S. and Canada while maintaining client relationships and achieving technical sales targets.

Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.

Support risk assessment, audit planning, and oversight of audit management and staff. Provide advisory services and ensure compliance with standards.

Develop and maintain ServiceNow ITSM solutions, including forms, flows, catalog items, integrations, workflows, business rules, and custom applications. Collaborate with product owners, process owners, platform engineers, Scrum Masters, and developers to define requirements and deliver quality solutions. Support Agile ceremonies, platform upgrades, patching, deployments, troubleshooting, debugging, and adherence to ServiceNow best practices. Apply prompt engineering, Now Assist, and agentic AI expertise.

Design, implement, and maintain enterprise Identity Provider (IdP) and ADFS authentication/federation services for millions of users. Configure federation trusts, SSO, MFA, PKI/certificate-based auth, integrate applications/APIs, troubleshoot tokens/claims, support Zero Trust and high-availability architectures, produce technical documentation, and collaborate across cyber, AD, cloud, and application teams.

Leads business analysis for enterprise applications and reporting initiatives. Translates stakeholder needs into requirements and functional or technical specifications, partners with IT on scalable solutions, manages project scope and risks, maintains process documentation, supports UAT and change readiness, and drives process standardization. Establishes business analysis standards and best practices across a growing, multi-location organization.

Design, build, and maintain scalable ETL/ELT pipelines and analytics-ready data models using Python and SQL. Implement GitLab CI/CD, develop dashboards in Tableau/Power BI, perform data cleaning and analysis, support modeling and AI initiatives, document metadata, and mentor junior staff while collaborating with cross-functional teams to deliver actionable insights.

Leads strategy, solutioning, and writing for complex federal proposals valued at $25M to $1B+. Shapes win themes, ensures compliance, identifies risks, partners with capture and solution teams, improves proposal operations, and mentors proposal staff. Supports multiple pursuits, large IDIQs, task orders, and AI-enabled proposal workflows while tailoring technical and management volumes to customer priorities and evaluation criteria.

Supports back-office operations for an ICAM program, coordinating PMO documentation, deliverables, procurements, assets, onboarding, reporting, compliance tracking, and communications. Maintains agendas, action items, trackers, logs, status reports, and program artifacts while improving workflows and documentation standards. Serves as a coordination hub across program management, finance, engineering, contracts, and compliance. The role is fully remote and requires an active Secret clearance.

The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.

Lead cloud financial governance for a federal enterprise: manage chargeback/showback, cost optimization, forecasting, anomaly detection, procurement alignment, and executive dashboards to ensure VA fiscal policy compliance and large-scale cloud spend oversight.