Top Chief of Staff Jobs

Serve as strategic partner to the SVP of Product to scale product leadership: run leadership rhythms, own headcount and budget planning, drive AI enablement, curate external product narrative, manage org-health metrics, and resolve cross-functional structural issues to increase decision speed and org effectiveness.

Leads the Office of the President, providing executive support, governance coordination, strategic initiative execution, stakeholder engagement, compliance oversight, board reporting, and operational leadership. Manages executive support staff, prioritizes the President’s schedule, coordinates Federal Reserve System committees and external engagements, facilitates cross-functional communication, and represents the President when appropriate. The role requires strong executive advising, program management, relationship management, communication, analytical thinking, and public-service commitment.

Chief of Staff to the Chief Technology & AI Officer, leading strategic initiatives, business operations, organizational health, communications, budgeting, and executive decision support. The role drives the rhythm of business, cross-team program execution, planning, resource allocation, governance, culture initiatives, and customer and partner engagement. It requires synthesizing complex information, influencing senior stakeholders, and creating clarity in ambiguous environments across an engineering organization.

The Chief of Staff partners with the CEO and Office of the CEO to drive critical initiatives, improve operational execution, and maintain organizational accountability. Responsibilities include preparing leadership materials, analyzing company performance, tracking projects and deadlines, escalating issues, conducting investigations, recommending improvements, managing CEO priorities, and representing the CEO when needed. The role requires strong analytical, organizational, communication, and problem-solving skills, plus a willingness to work 55–60 hours weekly and primarily onsite in New York City.

The Chief of Staff supports Oncology and Hematology Therapeutic Area leaders by managing strategic priorities, operational planning, leadership meetings, communications, and cross-functional initiatives. The role tracks milestones, coordinates stakeholders, facilitates decision-making, monitors organizational health, supports change management, and leads project and Operations Partner communities. It requires extensive experience in pharmaceutical or other regulated industries, global matrix environments, complex program leadership, executive communication, and strategic project execution.

Partner with the CEO to manage intake, readiness, governance, and execution of CEO-prioritized work. Lead an Associate Chief of Staff, coordinate board materials, refine executive presentations, drive follow-through across teams, and lead high-priority projects.

Work directly with both founders to execute strategic initiatives across go-to-market, product, recruiting, and operations. Build and scale outbound and GTM systems, translate founder and customer insights into action, lead cross-functional special projects, create repeatable processes, and use AI tools and automation to increase team leverage.

The Chief of Staff will work directly with founders to drive strategic and operational priorities across customer communications, contracts, compliance, sales, partnerships, market research, recruiting, finance, and company operations. Responsibilities include coordinating SOC 2 compliance, managing vendors and legal work, supporting business development, representing the company externally, identifying bottlenecks, and converting ambiguous priorities into organized projects with measurable progress.

Lead and coordinate complex, cross-functional technology programs as a strategic partner to CDAS leadership. Oversee operations, resource allocation, risk and governance, stakeholder communications, and change management. Prepare executive briefings, drive process improvements, and champion adoption of data practices and AI/ML tools to advance organizational objectives.

Lead and deliver medium-to-large cross-functional projects, manage the operational rhythm of the business (meetings, OKRs, reporting), drive internal communications and engagement, identify process improvements, manage risks/issues, and partner with stakeholders to ensure on-time, on-budget delivery.

Own the CEO’s calendar, follow-ups, project-management systems, hiring operations, content execution tracking, metrics, reporting, and special projects. The role protects executive focus, enforces accountability across teams, coordinates hiring pipelines, analyzes financial and performance data, and builds scalable operating rhythms. It is a high-trust Executive Operations position with a performance-based path toward Chief of Staff responsibilities.

Serve as the CEO's right hand to translate founder priorities into clear owners, deadlines, and execution. Lead cross-functional initiatives, run special projects end-to-end, build and maintain internal operating systems and dashboards, own staffing/pod allocation and the company financial model, and ensure follow-through across product, recruiting, finance, and ops.

Partner with the CEO to drive execution across planning, hiring, product, GTM, finance, and culture. Own operating cadence, track leadership priorities, lead cross-functional initiatives, prepare high‑stakes CEO communications, support board/investor and people processes, and build scalable systems to keep the company aligned and accountable.

Supports the executive team as a strategic advisor, coordinates cross-department communication, manages CEO-directed initiatives, prepares reports and presentations, leads meetings, tracks action items, and assists with company policies and procedures.

Serve as Chief of Staff to the CHRO, managing the People leadership operating cadence, leading cross-functional initiatives end-to-end, crafting executive communications, resolving issues proactively, and representing CHRO priorities across the organization.

The Chief of Staff serves as the CEO’s strategic advisor and execution partner, driving enterprise-wide initiatives, executive alignment, accountability, and organizational communication. Responsibilities include coordinating leadership meetings, tracking priorities, managing high-stakes projects, preparing board materials, improving governance and operating discipline, surfacing risks, and identifying growth opportunities. The role requires strong business, financial, strategic, communication, and organizational judgment in a fast-paced consulting and technology environment.

Serve as a force multiplier for the founders by converting priorities into operating plans, driving cross-functional initiatives, preparing data-informed recommendations, and establishing company operating cadences. Own strategic communications, board and investor materials, partnerships, and special projects. Solve unowned problems end-to-end, create durable systems, and support growth across product, go-to-market, finance, hiring, and operations.

Leads strategic and day-to-day operations for the Talent Team, serving as advisor and proxy to the Chief Talent Officer. Oversees strategic planning, project execution, accountability, executive communications, cross-functional initiatives, reporting, and data integrity. Manages a Project Manager or Executive Assistant, coordinates senior stakeholders, protects executive priorities, handles confidential information, and supports long-term organizational growth.

Serves as a strategic advisor and thought partner to the CEO, leading organizational planning, board relations, executive communications, cross-functional initiatives, special projects, and support operations. Oversees governance, stakeholder engagement, crisis communications, executive messaging, reception, print, mailroom, and organization-wide service functions while improving alignment, decision-making, efficiency, and execution.

Serve as the CEO’s operational extension, translating priorities into action, representing leadership in meetings, tracking decisions, managing follow-through, and driving cross-functional execution. Responsibilities include calendar and information management, travel logistics, hiring and onboarding initiatives, customer escalations, SOPs, reporting, planning cadences, and organizational accountability. The role requires high-agency judgment, adaptability, empathy, disciplined execution, and on-site collaboration in New York City.

Chief of Staff to the CEO responsible for driving company priorities, building the organization’s operating cadence, managing KPI reporting, leading cross-functional special projects, and increasing executive leverage. The role requires turning ambiguous problems into measurable plans, coordinating leaders and external partners, deploying AI effectively across operations, and improving organizational efficiency in a high-growth B2B SaaS environment.

Serves as the CEO’s strategic partner and execution lead, translating enterprise priorities into actionable plans and measurable outcomes. Coordinates executive leadership cadence, governance, board interactions, strategic initiatives, performance tracking, and cross-functional alignment. Develops executive analyses, dashboards, business cases, and recommendations while monitoring risks, dependencies, commitments, and organizational performance. Influences senior stakeholders without direct authority and supports strategic planning, transformation, operational improvement, and enterprise-wide execution.

Serve as the Chief Growth Officer’s strategic operator, leading GTM execution across Sales, Marketing, Channel, Customer Success, Product, and Finance. Own revenue operations, pricing, deal governance, forecasting, territory and quota planning, data unification, HubSpot architecture, executive dashboards, pipeline optimization, and Q2C processes. Manage a HubSpot Administrator, improve commercial analytics, establish operating cadence, and deploy AI-enabled workflows across the GTM technology stack.

The Chief of Staff serves as the CEO’s execution partner, driving cross-functional priorities across sales, editorial, events, marketing, finance, hiring, and product. Responsibilities include establishing leadership operating rhythms, leading launches and organizational initiatives, representing the CEO in key meetings, building scalable processes, and handling confidential people and transaction matters. The role requires strong execution, communication, financial literacy, discretion, technological curiosity, and the ability to influence without formal authority.

Serve as strategic partner to CEO/COO to translate strategy into action, drive cross-functional coordination, manage high-priority initiatives, prepare board materials, support executive decision-making, and during ramp-up act as Chief People Officer to shape culture and HR strategy.