Top Chief of Staff Jobs

Partner directly with the CEO to align leadership, run OKR and operating cadences, translate strategy into executable plans, lead cross-functional initiatives, prepare executive and board communications, and design scalable operational processes to drive company-wide execution.

Serve as trusted advisor to senior executives, driving strategic initiatives, stakeholder coordination, governance, performance reporting, risk and control oversight, and operational improvements. Lead projects, develop reporting (Excel/Power BI), prepare executive materials, support budgeting and talent planning, and ensure business continuity and compliance.

Serve as the CEO's strategic partner by leading the Office of the CEO, managing a dedicated team, orchestrating executive calendar and global travel, supporting Board governance and corporate development, aligning strategic communications, and implementing AI-driven productivity solutions to advance company priorities across Cloud, Cybersecurity, AI, and GTM initiatives.

Partner to the President & COO to drive execution, lead operating rhythms, prepare board/exec communications, own strategic cross-functional projects, apply data and AI to measure performance, and represent the principal with discretion.

Partner with founders to build and execute the B2B GTM motion: own pipeline from first meeting to signed contract, implement CRM and pipeline reporting, drive sales enablement and B2B marketing assets, map accounts and stakeholders, build top-of-funnel outreach, and translate market intelligence into refined packaging, pricing, and materials to land enterprise customers.

Partner with founders to build and run the B2B go-to-market: own pipeline from first meeting to signed contract, implement CRM and reporting, drive sales enablement and B2B marketing, build target account lists and top-of-funnel, map stakeholders, coordinate diligence/legal/security, and turn buyer feedback into sharper packaging and pricing.

Work directly with the founders to drive high-priority, cross-functional initiatives end-to-end. Manage operating rhythm (OKRs, leadership meetings), coordinate demos, manufacturing, fundraising, government relations, and hiring. Represent founders to defense stakeholders, organize high-urgency field missions and events, and streamline processes while operating in extreme ambiguity with frequent travel.

Lead AfroTech and live-event programs from concept through execution: define scope, timelines, budgets, GTM plans, and launch calendars; manage cross-functional teams and contractors; drive registrations, ticket sales, sponsorships, and post-event performance reporting.

Lead AfroTech and live events from concept to execution: scope, timelines, budgets, go-to-market, ticketing and pricing strategy. Manage cross-functional teams and contractors, coordinate calendars and sponsorships, drive registrations and member conversion, and report program performance.

Lead AfroTech and Blavity live/virtual event programs from concept to execution: define scope, budgets, GTM and launch plans; manage teams of employees and contractors; coordinate cross-functional workstreams (content, sponsorship, marketing, production); drive ticket sales, registrations, and membership conversion; own master event calendar and performance reporting; equip partners with assets and messaging.

Seeking a Chief of Staff across portfolio companies: an all‑star generalist with 2–4 years' experience in high‑growth startups, banking, consulting, or other high‑intensity environments. Candidates submit details for consideration against openings.

Serve as trusted advisor to the CTO Enterprise Platforms, driving strategy execution, rhythm of business, cross-team programs, and complex budget/forecast stewardship. Champion organizational health, partner with HR and Finance, lead executive communications and customer/partner engagement, and manage high-impact special projects to ensure alignment, accountability, and operational excellence across the Engineering organization.

Lead cross-functional programs for the SVP of Americas Sales, leveraging AI to design repeatable processes, manage executive engagements, track risks/opportunities, drive employee engagement initiatives, prepare executive presentations, and deliver process improvements to support sales strategy and outcomes.

Serve as strategic partner and proxy to the Co‑Heads of Global Investments, driving alignment across stakeholders, shaping leadership meetings, prioritizing HOI time, reviewing executive materials, and enabling cross‑functional initiatives. Act as a trusted advisor, influence without authority, and ensure decision‑ready communications while coordinating logistics, briefings, and events to advance investment priorities and executive objectives.

Partnering with the CEO, the Chief of Staff runs the executive operating system, enforces cross-functional prioritization, drives planning cycles and decision closure, surfaces unfiltered signal, builds internal narratives and playbooks, and leads high-impact projects end-to-end to enable reliable execution during rapid scaling.

Serve as Chief of Staff to the VP of Neuroscience Discovery Research, translating strategy into action by coordinating cross-functional initiatives, tracking progress, identifying risks, and enabling decision-making. Drive operational excellence, support leadership effectiveness, develop executive communications, and partner with Finance and Business Management to prioritize resources and improve processes. Facilitate external collaborations and capture organizational learnings to strengthen alignment and execution across discovery research teams.

Support the Chief Administrative Officer by overseeing administrative divisions, managing meetings, taking notes, drafting/editing high-level memos, reports and PowerPoint presentations, liaising with City agencies, troubleshooting issues, and ensuring confidentiality and proper escalation.

Serve as primary advisor to the Chair and Executive Director, oversee staff functions, coordinate intra-agency projects, streamline operations, draft executive materials, manage follow-up, embed DEI and racial equity across processes, liaise with government and public partners, and improve organizational effectiveness and project management practices.

Operate the CEO's operating system: set and own measurable company goals, run weekly leadership meetings, maintain company-level reporting sourced from the data warehouse, manage high-stakes cross-functional projects, prep executive and investor materials, and pressure-test decisions to ensure follow-through and outcomes.

Serve as a scientific and strategic partner to the Executive Director, synthesizing technical information, owning the directors operating rhythm, driving cross-disciplinary scientific programs from inception to execution, facilitating collaborations, preparing high-quality meeting materials and external communications, and handling confidential organizational and scientific matters with discretion.

Act as the CTO's right hand for R&D and Technology, owning program management, roadmaps, milestone tracking, dependency management across chemistry and engineering workstreams, translating between technical teams and business stakeholders, preparing executive/investor materials, and building operating cadence and decision processes without adding bureaucracy.

Serve as strategic partner to the President & CEO, oversee programmatic operations across youth development, reentry, wellness, and workforce initiatives; supervise program leaders; ensure compliance with funder requirements; coordinate cross-functional projects, performance management, and community partnerships to advance organizational priorities and program outcomes.

Partnering directly with the CEO, run leadership cadence, prepare board and investor materials, manage strategic special projects, vendor contracting, and support fundraising. Drive operational processes, accountability, and scale across cross-functional teams in an early-stage climate tech company.

The Chief of Staff will support the CEO and leadership team, manage stakeholder relationships, build content and communicate data-driven insights, and drive organization within the team. They will also lead special projects and help in recruiting and team culture initiatives.

The Chief of Staff will work closely with the CEO in key business functions such as strategy, recruiting, and operations. The role requires exceptional interpersonal skills, strategic thinking, and a passion for health. Responsibilities include recruiting, investor relations, internal communications, brand management, and special projects, adapting to the needs of the company.