Top Remote IT Jobs in St. Louis, MO

Reposted 4 Days AgoSaved
In-Office or Remote
Remote St. Louis, MO
Senior level
Senior level
Healthtech • Information Technology
The Senior IT Risk and Compliance Analyst manages vendor risk, ensures compliance with regulations, documents controls, and supports risk mitigation efforts across IT teams.
Top Skills: Audit MethodologiesCobitIso27001Iso27002NistServicenow Irm
Reposted 4 Days AgoSaved
Remote
Remote St. Louis, MO
Senior level
Senior level
Healthtech
The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.
Top Skills: JIRAMs ProjectServicenow PpmSmartsheet
Reposted 4 Days AgoSaved
Remote
Remote St. Louis, MO
Mid level
Mid level
Blockchain • Payments • Financial Services
The IT Systems Engineer will architect and maintain Tempo's IT infrastructure, focusing on identity management, endpoint security, and automation, ensuring efficient provisioning and compliance.
Top Skills: BashDnsGithub ActionsGoJamf ProJSONOidcOktaPythonRest ApisSAMLSentineloneTerraformZtna
Reposted 4 Days AgoSaved
Remote or Hybrid
Remote St. Louis, MO
138K-190K Annually
Senior level
138K-190K Annually
Senior level
Artificial Intelligence • Healthtech • Social Impact • Telehealth
Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.
Top Skills: AWSBashCi/CdGitGitGithub ActionsGoogle WorkspaceIamIpaasJamf ProJSONLambdaLinuxMicrosoft 365Microsoft IntuneOktaOkta WorkflowsPythonRest ApisWebhooksWorkato
Reposted 4 Days AgoSaved
Remote
Remote St. Louis, MO
3-5 Annually
Mid level
3-5 Annually
Mid level
Healthtech • Consulting • Pharmaceutical
The role involves managing user accounts, administering ITSM platforms, improving system performance, and providing technical support, focusing on IT service management best practices.
Top Skills: Active DirectoryItilManageengine Servicedesk PlusMs Powershell
Reposted 5 Days AgoSaved
Remote
Remote St. Louis, MO
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Healthtech • Pharmaceutical
The IT Systems Engineer III will improve Ophelia's IT systems through integration, automation, and security while managing IT projects, overseeing service providers, and ensuring compliance.
Top Skills: AIDlpDns AdministrationEdrGoogle Cloud PlatformIdp/IamItsmMdmSAMLScimZtna
Reposted 5 Days AgoSaved
Remote
Remote St. Louis, MO
211K-264K Annually
Expert/Leader
211K-264K Annually
Expert/Leader
Fintech • Healthtech • Analytics
Lead IT governance, financial oversight, strategy and operations for enterprise IT. Own budgeting/forecasting, capital planning, PMO, metrics, communications, and employee engagement to ensure strategy alignment, delivery discipline, and measurable outcomes.
Reposted 5 Days AgoSaved
Remote
Remote St. Louis, MO
128K-173K Annually
Expert/Leader
128K-173K Annually
Expert/Leader
Aerospace • Information Technology • Professional Services • Security • Software
Lead systems architecture and modernization projects, translating business needs into scalable technical solutions. Facilitate stakeholder communication, produce architecture artifacts, guide technical teams, and support implementation, estimates, and troubleshooting for cloud and legacy-to-web/mobile migrations.
Top Skills: AgileAWSMainframeAzureMobile DevelopmentUi/UxWeb Development
5 Days AgoSaved
In-Office or Remote
Remote St. Louis, MO
36K-128K Annually
Senior level
36K-128K Annually
Senior level
Agency • Information Technology
Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and other enterprise initiatives while coordinating cross-functional teams and multiple concurrent priorities.
Top Skills: AgileApplication ModernizationCloud TransformationScrumSdlcWaterfall
Reposted 5 Days AgoSaved
Remote
Remote St. Louis, MO
150K-187K Annually
Senior level
150K-187K Annually
Senior level
Fintech
Design and automate compliance systems to enhance efficiency in audit readiness. Collaborate with teams to integrate tools and optimize processes.
Top Skills: APIsBigQueryChatgptClaudeGCPGeminiGitPythonTerraform
5 Days AgoSaved
Remote
Remote St. Louis, MO
170K-201K Annually
Expert/Leader
170K-201K Annually
Expert/Leader
Aerospace • Information Technology • Professional Services • Security • Software
Provides strategic and technical leadership for complex Oracle ERP and enterprise IT environments. Develops multi-year technology roadmaps, cloud and hybrid-cloud architectures, integration frameworks, AI/ML and analytics solutions, security controls, and modernization strategies. Leads architecture reviews, governance, design, testing, cutover, optimization, and proof-of-concept efforts while ensuring scalability, compliance, high availability, and disaster recovery. Mentors teams and collaborates with CMS stakeholders, data engineers, middleware teams, and delivery partners.
Top Skills: APIsArtificial Intelligence (Ai)AWSEvent-Driven ArchitectureGoogle Cloud Platform (Gcp)IncortaMachine Learning (Ml)MessagingMicroservicesAzureMlopsObieeOktaOracle Analytics Server (Oas)Oracle Cloud Infrastructure (Oci)Oracle E-Business Suite (Ebs)Oracle Exadata Database MachineOracle HyperionOracle Identity And Access ManagementOracle Integration CloudOracle RacRestRpaSoaSoap
Reposted 5 Days AgoSaved
Remote
Remote St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Telehealth
Lead global IT operations for a HIPAA-regulated healthtech company, managing a small support team and hands-on ticketing. Build and maintain systems for compliance and visibility, optimize vendor costs, implement security/onboarding processes, drive process improvements with KPIs and automation, and serve as primary IT liaison to leadership and partners.
Top Skills: Google WorkspaceJAMFJIRAOktaSaaS
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Reposted 6 Days AgoSaved
Remote
Remote St. Louis, MO
94K-115K Annually
Senior level
94K-115K Annually
Senior level
Cloud • Information Technology • Productivity • Security • Software
Serve as IT Infrastructure Project Manager for public sector clients, delivering networking, wireless, UC, and data center/security projects on time and within budget. Manage schedules, budgets, vendors, stakeholders, risks, QA, and multiple concurrent projects. Provide client-facing communication, financial reporting, and leadership of internal and external teams while ensuring project profitability and adherence to methodology.
Top Skills: Data CenterNetworkingProject Management SoftwareSecurityUnified CommunicationWireless
6 Days AgoSaved
Remote
Remote St. Louis, MO
Mid level
Mid level
Artificial Intelligence • Greentech • Information Technology • Energy
Provides first-line technical support for corporate offices and data center environments. Responsibilities include troubleshooting users, installing and maintaining hardware and software, monitoring servers and networks, managing accounts and access permissions, enforcing security policies, maintaining asset inventories, creating knowledgebase content, training users, and supporting upgrades, cloud migrations, and infrastructure projects.
Top Skills: AWSAzureMulti-Factor Authentication
6 Days AgoSaved
Remote
Remote St. Louis, MO
204K-276K Annually
Expert/Leader
204K-276K Annually
Expert/Leader
Aerospace • Information Technology • Professional Services • Security • Software
Lead AI/ML strategy, architecture, development, deployment, and operationalization for CMS mission environments. Design predictive analytics, automation, and decision-support systems; oversee data pipelines, MLOps, model validation, explainability, and bias mitigation. Integrate secure AI solutions with cybersecurity, governance, compliance, and risk management requirements. Develop RAG and agentic AI capabilities, transition prototypes to production, advise stakeholders, support audits and governance reviews, and mentor engineering teams.
Top Skills: AgentforceAgentic AiAWSAws BedrockAws GovcloudAws SagemakerAzureAzure Ai FoundryAzure GovernmentGCPGoogle Vertex AiJavaMlopsPythonPyTorchRRetrieval-Augmented Generation (Rag)SalesforceTensorFlowZero Trust
6 Days AgoSaved
Remote
Remote St. Louis, MO
130K-161K Annually
Senior level
130K-161K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Designs, implements, and supports secure, scalable AWS and Azure infrastructure. Develops reusable Terraform and Ansible automation, CI/CD capabilities, and cloud infrastructure services. Configures cloud compute, storage, networking, databases, identity, security, monitoring, and backup solutions. Troubleshoots infrastructure and hosting issues, maintains technical and compliance documentation, and collaborates with customers and engineering teams using Agile and DevOps practices.
Top Skills: AnsibleAWSBashCi/CdGitIamLinuxAzurePowershellPythonRbacTerraformVpnWindows
Reposted 6 Days AgoSaved
Remote
Remote St. Louis, MO
179K-242K Annually
Senior level
179K-242K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Provide senior technical leadership and architectural oversight for large-scale EHR ecosystems. Define enterprise engineering strategy and roadmaps, ensure interoperability, scalability, availability, and cybersecurity, lead architectural governance and incident RCA, mentor engineering teams, coordinate with product owners and integrators, evaluate emerging technologies, and support proposals and customer engagements.
Top Skills: AWSAzureCerner/Oracle HealthDicomEpicFhirHl7
6 Days AgoSaved
Remote
Remote St. Louis, MO
65K-114K Annually
Mid level
65K-114K Annually
Mid level
Other • Retail
Leads multiple IT infrastructure implementation projects, including network, voice, wireless, cabling, telecommunications, branch openings, relocations, renovations, and technology upgrades. Manages scope, schedules, budgets, vendors, procurement, documentation, installation, testing, stakeholder communications, and operational readiness. Partners with Engineering, Facilities, Support, contractors, and business teams to ensure compliant, successful deployments.
Top Skills: CmdbCopper CablingEthernetMS OfficeOracleRoutingServicenowSharepointSwitchingTelecommunications InfrastructureVisioVoipWireless Networking
6 Days AgoSaved
Remote
Remote St. Louis, MO
Junior
Junior
Other
Supports digital products and enterprise systems by gathering requirements, documenting user stories, mapping business processes and data flows, resolving routine system issues, assisting with configuration changes, conducting functional testing, and maintaining system records. The role collaborates with technical and non-technical stakeholders, identifies process improvements, follows security and governance standards, and escalates complex issues as needed.
Top Skills: Data StructuresDigital ProductsEnterprise SystemsProcess Mapping ToolsSystem Integration
6 Days AgoSaved
Remote
Remote St. Louis, MO
50K-84K Annually
Junior
50K-84K Annually
Junior
Fintech • Payments • Financial Services
Performs IT audits assessing compliance with regulations and internal policies. Assists with audit planning, SOX ITGC testing, risk-based technology reviews, data analysis, issue validation, and remediation monitoring. Identifies control deficiencies, process inefficiencies, anomalies, and noncompliance, then communicates findings and recommendations to audit leadership and business stakeholders. Supports risk assessments and helps strengthen controls and reduce technology and business-process risk.
Top Skills: Data AnalyticsIt General Controls (Itgc)Sox
Reposted 6 Days AgoSaved
Remote
Remote St. Louis, MO
169K-233K Annually
Senior level
169K-233K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Lead a global IT support team, drive AI-first ITSM transformation (ServiceNow->Atomicwork), own ITSM processes and SLA governance, partner on JML/identity automation with Platform Engineering, manage vendors, run cross-functional programs, develop regional specialists, and participate in on-call escalations. Position requires East Coast timezone alignment and ~25% international travel.
Top Skills: Ai-Native ItsmAtomicworkConfluenceConsoleJIRAJsmOktaServicenowSlack
6 Days AgoSaved
Remote
Remote St. Louis, MO
130K-170K Annually
Senior level
130K-170K Annually
Senior level
Healthtech
Designs scalable, secure technology solutions connecting business objectives with application, integration, data, cloud, and enterprise systems. Responsibilities include developing architectures and roadmaps, modernizing processes through automation, governing APIs and data flows, incorporating security and compliance, guiding engineering teams, evaluating vendors, and facilitating stakeholder discovery workshops.
Top Skills: AIAnalyticsAPIsAWSAzureCloud ServicesCRMData WarehousingEdiEnterprise Integration PlatformsETLGCPWorkflow Platforms
6 Days AgoSaved
Remote
Remote St. Louis, MO
Senior level
Senior level
Transportation • Energy • Utilities • Industrial
Drive national sales and account growth for IT cooling equipment, services, and software. Develop strategic customer relationships, pursue new business, manage channel partners, lead proposals and negotiations, forecast revenue, analyze market trends, and represent the company at industry events. The role requires technical knowledge of HVAC, mission-critical infrastructure, power quality, and data center solutions, along with strong commercial, communication, and relationship-management skills.
Top Skills: Critical PowerData Center InfrastructureHvacIt CoolingMS OfficePower QualitySalesforce
Reposted 6 Days AgoSaved
Remote
Remote St. Louis, MO
70K-80K Annually
Senior level
70K-80K Annually
Senior level
Healthtech
Provide frontline and advanced application support for radiology imaging workflows: incident triage, user provisioning, configuration changes, DICOM troubleshooting, monitoring interfaces, coordinating with networks/storage/vendors, maintaining SOPs and knowledge base, delivering end‑user training and on‑call doctor support to meet SLAs.
Top Skills: DicomDicom TracesHipaaImaging ViewerItsm/TicketingModalityNetworkingPacsStorageWorklist
Reposted 6 Days AgoSaved
In-Office or Remote
Remote St. Louis, MO
Senior level
Senior level
Events • Gaming • News + Entertainment • Other
Lead end-to-end IT sourcing for hardware, software, SaaS, and security services. Develop sourcing strategies, run RFx and negotiations, draft and manage contracts, perform market and TCO analysis, mitigate risks, manage supplier performance, and align cross-functional stakeholders to optimize cost, performance, and vendor portfolios.
Top Skills: Collaboration ToolsContract Management SoftwareEnterprise SecurityNetworking HardwareProductivity SoftwareSaaS
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