Top Remote IT Jobs in St. Louis, MO

Provides global presales technical expertise for IT virtualization and infrastructure modernization solutions. Partners with account executives, engages customers, leads architecture discussions, presents solutions, advises on virtualization and migration strategies, develops service scopes, and supports pricing and delivery alignment. Requires deep virtualization architecture experience across VMware or related platforms, cloud, containers, security, AI, and infrastructure modernization.

Administer and optimize SQL Server databases while designing normalized schemas, mapping XML data, and developing SSIS-based ETL and migration pipelines. Responsibilities include database maintenance, backup and recovery, performance tuning, security controls, audit logging, testing, production cutovers, rollback planning, and ongoing migration support. The role also requires collaboration across development, testing, systems engineering, and business teams.

Oversee and finalize legal documents governing data sharing between Healthcare Fraud Prevention Partnership members and a trusted third party. Collaborate with CMS, HFPP leadership, partner engagement teams, and private payer partners on agreements, compliance, and negotiations. Present to management, support partner relationships, and ensure legal requirements are met for data governance and sharing.

Lead administration of Microsoft 365, Google Workspace, SaaS applications, Azure identity, and cloud infrastructure in a fully cloud-based organization. Provide Level 2/3 service desk escalation, execute migrations and cybersecurity projects, establish IT service processes, manage assets and vendors, and support onboarding, offboarding, incident response, change management, and M&A initiatives. The role partners with IT leadership and may help build and manage a growing internal technical team.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

Lead human-centered design and front-end engineering for the NIH Data Lakehouse: conduct user research and testing; create wireframes, prototypes, flows, and accessible interfaces; build scalable React/Next.js/TypeScript UI components; integrate with GraphQL and search services; contribute to design systems, component libraries, and platform-wide front-end best practices.

Maintains provider demographic, credentialing, enrollment, participation, roster, and directory data across healthcare systems. Reconciles rosters, audits data quality, resolves discrepancies affecting claims and participation, supports credentialing and enrollment, produces operational reports, communicates with stakeholders, and recommends process and tooling improvements.

Lead the strategic direction of frontend engineering, architecture, tooling, and standards. Build accessible, high-performing React or Angular applications, component libraries, design systems, deployment pipelines, and testing strategies. Drive modernization, performance, accessibility, and developer-experience initiatives while collaborating with product and design teams. Mentor engineers, influence cross-team technical decisions, and contribute across the full stack when needed. The role is remote, requires U.S. citizenship and the ability to obtain Public Trust 6C, and involves up to 10% travel.

Oversee multiple enterprise IT programs and projects for the CIDO organization. Responsibilities include managing schedules, budgets, risks, dependencies, staffing, requirements, testing, training, deployment, and change management. The role coordinates business and IT teams, facilitates stakeholder workshops, prepares executive dashboards, supports acquisition and delivery of IT solutions, and aligns digital strategies across corporate, sector, and functional leadership.

Leads enterprise architecture for Biogen’s Veeva ecosystem across Development, Quality, Regulatory, Safety, and Commercial functions. Translates business needs into scalable Veeva configurations and integrations, governs target-state architecture and platform standards, reviews solution designs, and oversees implementation and release planning. Mentors configuration teams, drives cross-vault consistency, manages architecture governance, aligns with Veeva product roadmaps, and advises IT leadership on platform strategy, investments, regulatory compliance, and business objectives.

Leads DevOps and application operations for critical enterprise applications. Responsibilities include production reliability, SLO and SLA management, incident response, release and deployment operations, observability, automation, capacity planning, disaster recovery, security compliance, performance optimization, stakeholder service reviews, and mentoring AppOps engineers. The role supports 24x7 reliability through on-call participation and cross-functional collaboration with engineering, cloud, security, and compliance teams.

Leads the design, development, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system architecture blueprints, selects technologies, integrates distributed systems across on-premise and cloud environments, optimizes performance, ensures compliance with DoD requirements, and leads engineering teams. Diagnoses system issues, implements solutions, and produces architecture documentation while supporting installation, migration, and configuration activities across multiple client locations.

Leads the architecture, design, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system blueprints, selects technologies, integrates distributed systems across on-premises, cloud, and hybrid environments, optimizes performance, resolves system issues, and ensures compliance with DoD requirements. Leads engineering teams, supports installation and migration at multiple locations, and documents architecture and implementation decisions.

Owns and leads Regulatory IT systems supporting Global Regulatory Affairs and R&D. Responsibilities include maintaining technology roadmaps, managing system enhancements and implementations, overseeing vendors and releases, providing production support, delivering integrations, conducting data mapping and validation, and ensuring GxP, HIPAA, GDPR, and CCPA compliance. The role serves as the primary IT partner for regulatory business units, manages budgets, and coordinates cross-functional teams delivering regulated technology initiatives.

Leads complex federal platform, cloud infrastructure, IT services, security, compliance, and disaster recovery initiatives. Coordinates AWS GovCloud infrastructure-as-code, deployment automation, observability, Zero Trust identity programs, FedRAMP High and DoD IL5 readiness, and operational resilience. Partners across Engineering, Security, Compliance, and Product to manage roadmaps, dependencies, risks, milestones, and audit readiness. The role also builds and mentors a Federal Platform Operations team and drives reliable, repeatable delivery practices.

Designs and maintains automated testing frameworks, scripts, datasets, and tools for complex data-driven software. Develops test plans, performs exploratory, database, API, performance, and integration testing, and validates data accuracy across systems. Analyzes defects and test metrics, supports CI/CD pipeline integration, and collaborates with application teams to resolve issues. The role also uses Playwright, database scripting, cloud technologies, Agile practices, and generative AI tools to improve software quality and efficiency.

Senior Cybersecurity Engineer to engineer and manage Tenable, Splunk, McAfee and other security tools; perform risk assessments, incident triage and coordination, system hardening, security posture assessments, develop security toolsets, and maintain awareness of threats and vulnerabilities in support of Department of State missions.

Designs and delivers secure, scalable cloud solutions across AWS and Azure for application, data, scientific, and research workloads. Partners with customers to translate requirements into architectures, develops Terraform infrastructure and automation, integrates DevOps and CI/CD capabilities, and manages solutions through implementation and transition to operations. Responsibilities include cloud networking, identity, security, monitoring, backup and recovery, troubleshooting, documentation, technical reviews, and collaboration within an Agile Cloud DevOps team.

Supports functional, exploratory, and automated testing for modern applications. Creates test cases, scripts, test data, and automated tests; validates APIs, integrations, messaging workflows, microservices, and user interfaces; documents results and defects; participates in triage, CI/CD testing, secure data handling, observability, and release documentation. Collaborates with product, development, DevSecOps, and operations teams while learning testing standards and delivery processes.

Leads functional and automated testing for complex modern, cloud-based applications. Develops test strategies, plans, cases, and automation for unit, API, integration, UI, performance, security, and regression testing. Validates Kafka-based workflows, microservices, serverless systems, data pipelines, and CI/CD releases. Partners with engineering and DevSecOps teams on defect prevention, security, observability, environment readiness, root-cause analysis, and operational quality. Maintains audit-ready documentation and communicates risks and recommendations to stakeholders.

Design and lead development of instructor-led, virtual, and hybrid software training. Collaborate with SMEs and agencies to create ADDIE-based curricula, ensure Section 508 compliance, produce webinars, web-based training, user guides and online help, and evaluate training effectiveness for USPS implementations.

Act as the technical lead for field sales, manage evaluations, deliver on-site and remote demos, prepare SOWs/RFIs/RFPs, respond to security questionnaires, train sales teams, and support sales across U.S. and Canada while maintaining client relationships and achieving technical sales targets.

Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.

Join WOW company's talent pool for various roles including social media, graphic design, customer service, HR recruitment, data analysis, project management, and more. Participate in team meetings and maintain a positive attitude while developing skills.

Support risk assessment, audit planning, and oversight of audit management and staff. Provide advisory services and ensure compliance with standards.