Top Remote IT Jobs in St. Louis, MO

Principal frontend-focused software engineer responsible for leading frontend architecture, standards, tooling, accessibility, performance, testing, and deployment practices. The role delivers scalable customer-facing web applications, component libraries, and design systems using React or Angular. It includes cross-functional product collaboration, technical decision-making, mentoring, modernization initiatives, and occasional full-stack work. The position is remote, requires U.S. citizenship, Public Trust 6C eligibility, and approximately 0–10% business travel.

Designs and operates IT services for laboratory environments, including networks, compute, security, private cloud, and SDN platforms. Translates business and IT requirements into secure, standardized architectures and operational processes. Leads deployments, design reviews, documentation, incident gap analysis, automation, and infrastructure optimization. Requires extensive enterprise networking, datacenter, virtualization, Linux, security, and ITIL experience.

Designs and operates laboratory IT services covering compute, networks, security, private and public cloud, and software-defined networking. Translates business requirements into secure, high-performance service offerings; defines architectures, configurations, processes, and operational procedures. Leads implementations, design reviews, documentation, incident analysis, gap remediation, automation, and infrastructure optimization across global laboratory environments.

Lead an Automation Center of Excellence to build and maintain IaC, automation pipelines, and configuration management across colo and multi-cloud (Azure, GCP, OCI). Drive standardization, governance, security controls, CI/CD integration, incident management, GitOps and policy-as-code adoption. Mentor team members, manage vendor relationships, measure automation KPIs, and provide executive reporting. Participate in on-call rotation and work outside normal hours as needed.

Lead and manage a virtualization team operating mixed VMware and Nutanix environments. Ensure availability, performance, security, upgrades, migrations, automation, capacity planning, incident management, vendor relations, KPIs, and alignment with cloud and business objectives.

The IT Project Engineer is responsible for onboarding clients into Atlas Technica's support model, implementing secure solutions, and ensuring documentation meets compliance standards, while collaborating with other teams and providing oversight to junior engineers.

Define and execute enterprise strategy for data, analytics, AI, automation, and innovation. Build data governance, architecture, engineering, BI, and AI adoption (including Generative and Agentic AI). Identify high-value use cases, scale emerging technologies, partner with IT functions, lead high-performing teams, advise executives and board-level stakeholders, and ensure security, privacy, governance, and responsible AI compliance.

Drive net-new enterprise IT services revenue by owning full sales lifecycle: prospecting, executive engagement, solution positioning, collaboration with presales/delivery, pipeline management, and closing multi-year managed services, application modernization, and digital transformation deals to meet $5M–$10M annual targets.

The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.

The IT Systems Engineer will architect and maintain Tempo's IT infrastructure, focusing on identity management, endpoint security, and automation, ensuring efficient provisioning and compliance.

Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.

The role involves managing user accounts, administering ITSM platforms, improving system performance, and providing technical support, focusing on IT service management best practices.

Lead systems architecture and modernization projects, translating business needs into scalable technical solutions. Facilitate stakeholder communication, produce architecture artifacts, guide technical teams, and support implementation, estimates, and troubleshooting for cloud and legacy-to-web/mobile migrations.

Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and other enterprise initiatives while coordinating cross-functional teams and multiple concurrent priorities.

Provides strategic and technical leadership for complex Oracle ERP and enterprise IT environments. Develops multi-year technology roadmaps, cloud and hybrid-cloud architectures, integration frameworks, AI/ML and analytics solutions, security controls, and modernization strategies. Leads architecture reviews, governance, design, testing, cutover, optimization, and proof-of-concept efforts while ensuring scalability, compliance, high availability, and disaster recovery. Mentors teams and collaborates with CMS stakeholders, data engineers, middleware teams, and delivery partners.

Lead global IT operations for a HIPAA-regulated healthtech company, managing a small support team and hands-on ticketing. Build and maintain systems for compliance and visibility, optimize vendor costs, implement security/onboarding processes, drive process improvements with KPIs and automation, and serve as primary IT liaison to leadership and partners.

Serve as IT Infrastructure Project Manager for public sector clients, delivering networking, wireless, UC, and data center/security projects on time and within budget. Manage schedules, budgets, vendors, stakeholders, risks, QA, and multiple concurrent projects. Provide client-facing communication, financial reporting, and leadership of internal and external teams while ensuring project profitability and adherence to methodology.

Provides first-line technical support for corporate offices and data center environments. Responsibilities include troubleshooting users, installing and maintaining hardware and software, monitoring servers and networks, managing accounts and access permissions, enforcing security policies, maintaining asset inventories, creating knowledgebase content, training users, and supporting upgrades, cloud migrations, and infrastructure projects.

Lead AI/ML strategy, architecture, development, deployment, and operationalization for CMS mission environments. Design predictive analytics, automation, and decision-support systems; oversee data pipelines, MLOps, model validation, explainability, and bias mitigation. Integrate secure AI solutions with cybersecurity, governance, compliance, and risk management requirements. Develop RAG and agentic AI capabilities, transition prototypes to production, advise stakeholders, support audits and governance reviews, and mentor engineering teams.

Designs, implements, and supports secure, scalable AWS and Azure infrastructure. Develops reusable Terraform and Ansible automation, CI/CD capabilities, and cloud infrastructure services. Configures cloud compute, storage, networking, databases, identity, security, monitoring, and backup solutions. Troubleshoots infrastructure and hosting issues, maintains technical and compliance documentation, and collaborates with customers and engineering teams using Agile and DevOps practices.

Provide senior technical leadership and architectural oversight for large-scale EHR ecosystems. Define enterprise engineering strategy and roadmaps, ensure interoperability, scalability, availability, and cybersecurity, lead architectural governance and incident RCA, mentor engineering teams, coordinate with product owners and integrators, evaluate emerging technologies, and support proposals and customer engagements.

Leads multiple IT infrastructure implementation projects, including network, voice, wireless, cabling, telecommunications, branch openings, relocations, renovations, and technology upgrades. Manages scope, schedules, budgets, vendors, procurement, documentation, installation, testing, stakeholder communications, and operational readiness. Partners with Engineering, Facilities, Support, contractors, and business teams to ensure compliant, successful deployments.

Supports digital products and enterprise systems by gathering requirements, documenting user stories, mapping business processes and data flows, resolving routine system issues, assisting with configuration changes, conducting functional testing, and maintaining system records. The role collaborates with technical and non-technical stakeholders, identifies process improvements, follows security and governance standards, and escalates complex issues as needed.

Performs IT audits assessing compliance with regulations and internal policies. Assists with audit planning, SOX ITGC testing, risk-based technology reviews, data analysis, issue validation, and remediation monitoring. Identifies control deficiencies, process inefficiencies, anomalies, and noncompliance, then communicates findings and recommendations to audit leadership and business stakeholders. Supports risk assessments and helps strengthen controls and reduce technology and business-process risk.

Lead a global IT support team, drive AI-first ITSM transformation (ServiceNow->Atomicwork), own ITSM processes and SLA governance, partner on JML/identity automation with Platform Engineering, manage vendors, run cross-functional programs, develop regional specialists, and participate in on-call escalations. Position requires East Coast timezone alignment and ~25% international travel.