Top Remote IT Jobs in St. Louis, MO

Leads enterprise IT operations supporting cloud infrastructure, applications, identity services, cybersecurity coordination, change governance, and end-user support. Oversees Azure modernization, ServiceNow and Microsoft 365 operations, production releases, compliance activities, incident response, vendors, contractors, and cross-functional technical teams. Provides strategic guidance on modernization, service transformation, operational readiness, and technology investments supporting federal programs and mission operations.

Develop and implement agentic and generative AI solutions, including LLMs, RAG, AI security, and related platforms. Support research and development, technical proposals, prototyping, and client consulting. Apply data science and engineering best practices, integrate and analyze data, gather requirements, and translate technical concepts for clients and stakeholders.

Develops and maintains synchronous and asynchronous training content for new IT processes using the ADDIE model. Creates courseware, lesson plans, simulations, job aids, assessments, and multimedia learning assets. Collaborates with stakeholders to document workflows, revise SAP processes, ensure Section 508 and SCORM compliance, conduct quality assurance, deploy training through learning platforms, and measure effectiveness. Requires extensive SAP, instructional development, technical writing, communication, and virtual training experience.

Develop and maintain enterprise Java web applications using Spring Boot, REST, SOAP, SQL, and Flyway. Lead secure software development across the SDLC, including CI/CD automation, testing, vulnerability scanning, production support, troubleshooting, and root-cause analysis. Collaborate on integrations, modernization, Agile delivery, technical documentation, and application architecture. Evaluate and implement AI-enabled capabilities while maintaining security and regulatory compliance. The role is remote and requires eligibility for Public Trust screening.

Provide frontline remote IT support, troubleshoot user access and device issues, manage onboarding and offboarding, configure accounts and permissions, triage tickets, maintain device inventory, ship equipment, and document resolutions. Support macOS, Windows, and iOS devices across platforms including Google Workspace, Microsoft 365, Salesforce, Slack, and internal applications. Participate in rotating weekend on-call coverage and quarterly Austin meetings.

Leads Microsoft 365 strategy, operations, security, governance, and adoption while overseeing Azure, infrastructure, business-critical applications, vendors, and a distributed IT team. Partners with business and technology leaders to deliver cost-effective solutions, improve service consistency, maintain asset and licensing compliance, and manage disaster recovery and business continuity.

Develop and maintain PHP web applications for a federal client, including application migration, requirements analysis, API and database integration, testing, deployment, monitoring, maintenance, outage contingency planning, and performance improvements. The role is client-facing, collaborates with technical and design teams, manages multiple priorities, and provides guidance to junior developers. Remote work is available, with no travel required.

Leads project management, Agile delivery, and business process analysis across multiple Scrum and Kanban teams. Responsibilities include schedule and milestone tracking, risk mitigation, Agile ceremony facilitation, Jira workflow management, requirements gathering, user story creation, process optimization, and Confluence documentation. The role coordinates cross-functional stakeholders, monitors sprint metrics, maintains delivery roadmaps, and uses AI tools to improve tracking, automation, and reporting.

Leads Padagis’s global IT organization, strategy, roadmap, operations, infrastructure, security, applications, and enterprise systems. Oversees budgets, vendors, contracts, compliance, risk management, incident response, SAP implementations, system upgrades, and integrations following acquisitions. Aligns technology initiatives with business objectives and leads IT professionals across a regulated pharmaceutical environment.

Own day-to-day IT operations for a global remote workforce, including end-user support, device and access management, onboarding and offboarding, internal systems administration, security controls, compliance audits, process automation, vendor management, and asset tracking. The role partners with Compliance, Engineering, DevOps, and HR to maintain reliable, secure, and efficient IT infrastructure while supporting growth and regulated-industry requirements.

Leads global strategic sourcing and category management for IT and indirect spend. Develops sourcing strategies, negotiates contracts, manages supplier performance and risk, drives cost savings and procurement transformation, ensures compliance, and leads a global sourcing team. Partners with IT, Finance, Legal, Operations, and business stakeholders across regions while monitoring KPIs and improving sourcing processes.

Provides embedded training and end-user support for Oracle Health EHR workflows in the Veterans Affairs EHR modernization program. Coordinates site-specific support, refresher training, office hours, coaching, job aids, and learning interventions. Assesses training gaps, tracks user feedback and recurring issues, recommends content updates, validates proficiency, and supports change-management activities. Collaborates with SMEs, local sites, training stakeholders, and program offices to improve adoption and readiness.

Instructor-led AI and machine learning training covering theory, data preprocessing, algorithms, model building, analytics, real-time projects, case studies, and practical business and IT applications. Participants use Python, TensorFlow, and Scikit-learn and receive certification upon successful completion.

Manages the full lifecycle of patient safety and compliance cases for OPTN member organizations. Responsibilities include intake, triage, clinical review, investigations, stakeholder coordination, corrective action tracking, trend analysis, reporting, documentation, and process improvement. The role supports HRSA and OPTN committees, handles sensitive healthcare information, manages multiple concurrent cases, and assesses compliance risks and patient safety concerns.

Supports IT solution design and implementation, analyzes cybersecurity protocols and recommends improvements, and collaborates with data science teams to analyze data and generate actionable insights. The internship provides hands-on experience, mentorship, professional development, and exposure to aerospace technology. Candidates must be enrolled in a relevant bachelor's or higher degree program, maintain a 3.0 GPA, and graduate in December 2027 or later.

Summer intern assisting with IT solution design and implementation, supporting cybersecurity initiatives through security protocol analysis, and collaborating with data science teams to analyze data and generate actionable insights. The role offers hands-on experience, mentorship, and professional development within Honeywell Aerospace. Candidates must remain enrolled in a relevant degree program, maintain at least a 3.0 GPA, and meet U.S. person requirements.

Summer 2027 interns will support IT solution design, cybersecurity initiatives, and data science projects at Honeywell Aerospace. Responsibilities include implementing business-focused IT solutions, analyzing security protocols and recommending improvements, and collaborating with data science teams to generate actionable insights. Interns receive hands-on experience, mentorship, professional development, relocation benefits, and short-term housing when eligible. The role is available at multiple U.S. locations.

Leads provider contracting and network development for the World Trade Center Health Program. Responsibilities include assessing network gaps, recruiting providers, negotiating agreements and reimbursement structures, managing contract lifecycles, overseeing network adequacy and access reporting, improving workflows, mitigating network risks, and coordinating with credentialing, finance, compliance, and provider data teams.

Provide hands-on IT administration for approximately 230 employees across macOS and Windows. Responsibilities include Tier 1 and Tier 2 support, SaaS and identity administration, endpoint management, onboarding and offboarding, asset inventory, compliance reporting, workflow monitoring, scripting, documentation, lab and VDI support, and vendor coordination.

Leads IT operations and serves as the company’s Microsoft and identity security authority. Owns Entra ID architecture, privileged access, lifecycle automation, SSO, endpoint platforms, SaaS integrations, compliance controls, audit readiness, and identity threat detection. Directs IT staff, manages projects and vendors, supports engineering environments, and automates provisioning and reporting using Graph, PowerShell, Power Automate, and Python. Partners across Security, Engineering, Marketing, and Web to remediate risks and deliver secure, auditable infrastructure.

Leads integration of 5G Core, optical transport, fiber, and IP network infrastructure for the Army TEN-M program. Oversees fiber route activation, DWDM and ROADM configuration, optical alignment, lightpath provisioning, system acceptance testing, troubleshooting, interoperability validation, and service optimization. Coordinates with construction, OSP, QA/QC, and NOC teams while developing integration procedures and ensuring security, operational, and documentation requirements are met.

Lead enterprise database services across Oracle, SQL Server, AWS, and Azure platforms for the Department of Veterans Affairs. Provide technical leadership for database operations, modernization, availability, disaster recovery, security compliance, observability, governance, and performance reporting. Coordinate cross-functional and multi-vendor engineering teams, support cloud transitions and virtualization migrations, maintain audit readiness, and align database services with federal cybersecurity frameworks and VA operational requirements.

Serves as the senior technical authority for enterprise network operations and engineering. Architects secure voice, video, wireless, and data networks; develops HLDs and LLDs; integrates Cisco technologies; and leads modernization, automation, risk assessment, and technical decision-making. The role advises customer leadership, resolves complex enterprise issues, validates solutions through hands-on engineering, mentors technical teams, and maintains the enterprise technology strategy and roadmap.

Leads systems-of-systems architecture, integration, testing, deployment, and lifecycle engineering for Department of the Air Force Zero Trust gateway capabilities. Directs cross-functional engineering teams across networking, compute and storage, hardware, software, and cybersecurity. Owns technical strategy, requirements, risk mitigation, RMF and authorization activities, testing, fielding, and operational transition. Delivers technical briefings, decision papers, and roadmap recommendations to senior military and civilian stakeholders.

Leads the IT Order to Cash function and roadmap across SAP platforms, including configuration, integration, customization, master data, reporting, and analytics. Manages SAP OTC process improvements, KPIs, OKRs, stakeholder communications, solution design, and SAP BTP innovation. Supervises and develops business analysts, software engineers, and subject matter experts while aligning technology delivery with business transformation goals.