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Top Remote Python Jobs in San Diego, CA

Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
129K-178K Annually
Senior level
129K-178K Annually
Senior level
Healthtech
The Lead Software Engineer oversees the design and delivery of foundational services for real-time recommendations while mentoring teams and ensuring robust, auditable systems using advanced state management and transactional patterns.
Top Skills: DebeziumFlywayHibernateJavaJooqJpaKotlinLiquibaseMySQLNode.jsOpenapiOpentelemetryPostgresPythonTypeormTypescript
Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
107K-147K Annually
Senior level
107K-147K Annually
Senior level
Healthtech
The Senior Software Engineer will design and implement stateful services for real-time decisioning systems, focusing on state machines and reliability in distributed environments.
Top Skills: GoJavaKotlinPython
Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
129K-178K Annually
Senior level
129K-178K Annually
Senior level
Healthtech
The Lead Software Engineer designs and maintains a high-performance decision engine, focusing on low-latency services and robust API development while ensuring compliance and observability. Responsibilities include managing rules execution, performance engineering, and leading technical reviews.
Top Skills: AntlrDroolsGoogle CelIbm OdmJavaKafkaKotlinNettyOpaPythonSpring Boot
18 Days AgoSaved
Remote
Remote San Diego, CA
220K-250K Annually
Mid level
220K-250K Annually
Mid level
Software
Serve as the technical contact for strategic partners to integrate Transmit Security's CIAM, authentication, and fraud APIs. Provide code samples, reference architectures, integration reviews, troubleshooting, and partner-facing assets. Support enablement via workshops, solution design, and pre-sales engineering while feeding partner feedback into product roadmap.
Top Skills: APIsAuthenticationCiamCloud ArchitecturesFraud PreventionGoJavaJavaScriptMfaOauthOidcPasswordlessPythonSAMLSdks
18 Days AgoSaved
Remote
Remote San Diego, CA
165K-200K Annually
Senior level
165K-200K Annually
Senior level
Artificial Intelligence • Cloud • Mobile • Security • Software
Design, build, and operate high-performance distributed authentication and real-time inference services. Implement scalable cloud APIs, distributed training and deployment pipelines, CI/CD, observability, and reliability practices. Lead incident response, on-call rotations, staged rollouts, and post-incident improvements while managing model lifecycle, data quality, and production monitoring.
Top Skills: Aws KinesisDockerDynamoDBGithub ActionsGoGrafanaJenkinsKubernetesLinuxMySQLPrometheusPythonRedisS3
Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
144K-299K Annually
Senior level
144K-299K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
As a Principal Software Dev Engineer, lead full-stack engineering, oversee complex initiatives, mentor engineers, and align technical strategies with business goals to enhance content management systems.
Top Skills: AIAWSCloud TechnologiesFastapiLarge Language ModelsNext.JsPythonReactTypescript
18 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Artificial Intelligence • Information Technology
Drive end-to-end enterprise deployments of Synthflow's no-code voice AI platform: design solutions, build integrations with CRMs/telephony, troubleshoot production issues, optimize adoption, and translate customer needs into product improvements.
Top Skills: Ai OrchestrationAi/MlAPIsContact Center SystemsCrmsJavaScriptLlmsLow-Code IntegrationsPromptingPythonSipTelephony Systems
18 Days AgoSaved
Easy Apply
Remote
Remote San Diego, CA
Easy Apply
120K-150K Annually
Expert/Leader
120K-150K Annually
Expert/Leader
Healthtech
Lead architecture and delivery for document generation systems, mentor engineers, build greenfield internal tooling, enforce shift-left quality practices, and ensure HIPAA-compliant, secure integrations with data science and clinical platforms.
Top Skills: Api GatewayAws LambdaCi/CdCloudFormationDynamoDBHipaaLintersNistOwaspPre-Commit HooksPythonReactServerlessTypescript
Reposted 18 Days AgoSaved
Easy Apply
Remote
Remote San Diego, CA
Easy Apply
105K-120K Annually
Mid level
105K-120K Annually
Mid level
Security • Software • Cybersecurity
Develop AI-powered applications, integrate machine learning models with user interfaces, build data pipelines, and collaborate with cross-functional teams.
Top Skills: AngularApi GatewayAWSBedrockCSSDynamoDBEcsEventbridgeGitGoHTMLJavaScriptKinesisLambdaMongoDBMySQLNode.jsPostgresPythonPyTorchRdsReactS3Scikit-LearnTensorFlowVue
Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
175K-240K Annually
Expert/Leader
175K-240K Annually
Expert/Leader
Security • Database • Cybersecurity
The Principal Engineer will architect and build scalable payments applications, mentor engineers, and collaborate on technology solutions while ensuring code quality and best practices.
Top Skills: APIsArgoAWSCi/CdCloud SaasDockerGithub ActionsGrafanaJavaKafkaKubernetesMicroservicesOpen TelemetryPythonSpring Framework
Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Healthtech
Develop and implement scalable solutions, collaborate with teams using Agile, and mentor junior engineers while ensuring security and performance.
Top Skills: AirflowEltETLPythonSparkSQL
18 Days AgoSaved
Easy Apply
Remote
Remote San Diego, CA
Easy Apply
172K-215K Annually
Senior level
172K-215K Annually
Senior level
Aerospace • Big Data • Greentech • Hardware • Social Impact
Design, deploy, and operate compute services for on-premises and cloud satellite imaging platforms. Build reproducible, scalable, highly available deployments, troubleshoot distributed systems, optimize constrained environments, document and automate operations, and participate in on-call rotations to ensure reliability for customer-facing and air-gapped deployments.
Top Skills: AlloyAnsibleBashCudaGitopsGrafanaHelmJIRAK3SKubernetesKustomizeOpentelemetryPrometheusProxmoxPythonRke2TalosTerraform
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19 Days AgoSaved
Remote
Remote San Diego, CA
90K-105K Annually
Junior
90K-105K Annually
Junior
Software • Automation
Design, build, and maintain FastAPI back-end APIs and React+TypeScript front-ends for the 340BCheck product. Participate in full SDLC, write unit/integration tests, translate product requirements into technical solutions, perform code reviews, and collaborate with cross-functional teams.
Top Skills: AWSFastapiMySQLPythonReactSQLTypescript
19 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
240K-330K Annually
Expert/Leader
240K-330K Annually
Expert/Leader
Artificial Intelligence • Automotive • Machine Learning • Transportation
Lead research and development of motion planning, trajectory generation, and control algorithms and ML models for autonomous vehicles. Architect simulation and validation scenarios to expand ODDs and ensure safety. Collaborate cross-functionally, document designs and results, and mentor junior engineers to improve system robustness and reliability.
Top Skills: C++Cpu ProfilingDdsGpu ProfilingKernel DebuggingLinuxPythonRosRustShell/TerminalSimulation Systems
19 Days AgoSaved
Remote
Remote San Diego, CA
Junior
Junior
Artificial Intelligence • Information Technology • Sales
Build and maintain GTM systems, automations, and data pipelines that connect Sumble data to CRM, sequencing, analytics, and campaign infrastructure. Create dashboards, tooling, attribution, enrichment pipelines, and run growth experiments to scale marketing and revenue operations.
Top Skills: Api IntegrationsHubspotJavaScriptMakeN8NPythonSalesforceSQLTrayZapier
19 Days AgoSaved
Easy Apply
In-Office or Remote
Remote San Diego, CA
Easy Apply
150K-185K Annually
Senior level
150K-185K Annually
Senior level
Financial Services
Build full-stack, user-facing features alongside ML engineers using TypeScript, Node.js, GraphQL, and Postgres. Implement and integrate AI/LLM/ML tools, own features end-to-end from design to production, maintain scalability/reliability/observability, participate in code reviews and design discussions, and contribute to product ideation and RFCs.
Top Skills: GraphQLLlmsMl/AiNode.jsPostgresPythonReactTypescript
19 Days AgoSaved
Easy Apply
Remote
Remote San Diego, CA
Easy Apply
200K-260K Annually
Senior level
200K-260K Annually
Senior level
Artificial Intelligence • Software • Generative AI
Design and build near production partner solutions on Glean, own end-to-end architecture, automate deployments with IaC, create reusable patterns and docs, advise strategic partners, lead workshops, enable partner teams, align technical plans with GTM, and collaborate across Sales, Product, and Engineering.
Top Skills: Amazon Web Services (Aws)APIsGleanGoGoogle Cloud Platform (Gcp)Google DriveInfrastructure-As-CodeJavaScriptAzureMicrosoft TeamsNetworkingPythonSlackTypescript
Reposted 19 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
Senior level
Senior level
Fintech • Payments
Lead the design and development of scalable data acquisition systems, architect core platform components, and mentor engineers while ensuring data quality and system reliability.
Top Skills: GoJavaPythonScala
19 Days AgoSaved
Remote
Remote San Diego, CA
100K-200K Annually
Senior level
100K-200K Annually
Senior level
Aerospace
Lead development of SDR embedded software for LEON3 softcore processors: design and implement embedded C/C++ and Python firmware, autoboot FPGA/softcore loading, integrate SpaceWire and other interfaces, manage RTEMS cross-compilation, perform HW/SW integration, debugging, verification, and maintain requirements traceability and documentation.
Top Skills: AssemblyBccCC++CanCcsds Proximity-1EthernetFpgaGaisler RtemsGrmonLeon3LinuxMicrochip Proasic3PythonRccSdrSpacewireXilinx Kintex Ultrascale
19 Days AgoSaved
Remote
Remote San Diego, CA
195K-235K Annually
Senior level
195K-235K Annually
Senior level
Cloud • Information Technology
Lead design and scaling of a high-performance, data-intensive storage layer for network telemetry. Co-own multi-year roadmap, collaborate with product/support/sales, and solve challenging distributed storage and query-performance problems at large scale.
Top Skills: CDistributed FilesystemsEnvoyExpressGitGoGrpcHaproxyJavaScriptJenkinsJIRAKafkaMySQLNode.jsObject StoragePostgresPythonReactRedisRest/JsonRustTimeseries Databases
Reposted 19 Days AgoSaved
Remote
Remote San Diego, CA
136K-266K Annually
Senior level
136K-266K Annually
Senior level
Big Data • Cloud • Software • Analytics
Design and implement cloud infrastructure and data pipelines using GCP services, optimize performance, and collaborate with teams for seamless integration and automation.
Top Skills: Apache AirflowApache KafkaBashBig QueryCloud BuildCloud LoggingCloud MonitoringCloud StorageDataflowDataprocDatastreamDockerElk StackGitlab Ci/CdGoogle Cloud Platform (Gcp)GrafanaKubernetesPrometheusPub/SubPythonTerraform
Reposted 19 Days AgoSaved
Remote
Remote San Diego, CA
130K-155K Annually
Senior level
130K-155K Annually
Senior level
Big Data • Information Technology • Security • Software • Analytics • Cybersecurity
The Senior Software Engineer II at Bitsight will build and operate large-scale data pipelines, helping to enhance the Security Ratings product through software development and integration of new data sources.
Top Skills: Apache IcebergAWSCi/CdHadoopJavaKubernetesPythonSpark
Reposted 19 Days AgoSaved
Remote
Remote San Diego, CA
110K-130K Annually
Mid level
110K-130K Annually
Mid level
Software
The AI First Software Engineer will design and build scalable marketplace systems, leveraging AI tools for development and operational efficiency, while collaborating with cross-functional teams.
Top Skills: .NetAWSGoJavaKotlinPythonReactRubySQLTypescript
Reposted 19 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
122K-146K Annually
Senior level
122K-146K Annually
Senior level
Fintech • Payments
Lead the design and development of scalable data acquisition systems, architect core components, and mentor engineers while collaborating across teams to fulfill data integration needs.
Top Skills: GoJavaPythonScala
19 Days AgoSaved
Easy Apply
Remote or Hybrid
Remote San Diego, CA
Easy Apply
Senior level
Senior level
Mobile • Security • Software • Cybersecurity
Design, build, and maintain automation frameworks and tooling for Commander CLI and SDKs. Create end-to-end, integration, and system tests, integrate automation into CI/CD, validate cross-platform and secure workflows, analyze failures, and mentor other automation engineers to improve reliability and test architecture.
Top Skills: .NetAnsibleAuthenticationAWSAzure DevopsCi/CdCliEncryptionGithub ActionsGovcloudJenkinsKubernetesLinuxmacOSNunitPytestPythonSdksSecrets ManagementTerraformWindows
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