Top Remote Python Jobs in Houston, TX

Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
135K-170K Annually
Senior level
135K-170K Annually
Senior level
Information Technology • Software
The Senior Software Developer II - Full Stack will design and develop scalable systems, leading projects while mentoring junior staff and engaging with stakeholders. The role emphasizes technical leadership, problem-solving in software development, and innovative processes in cloud and AI technologies.
Top Skills: Ai ToolingsAWSAzureDockerFirestoreGCPGitJavaKubernetesMongoDBMySQLNext.JsNode.jsPostgresPythonReactRuby On Rails
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Information Technology • Financial Services
The Backend Engineer will design, build, and scale Veda's backend systems, ensuring reliability and performance for DeFi applications.
Top Skills: AWSAzureC++DockerGCPGoJavaKubernetesMySQLPostgresPythonRust
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Artificial Intelligence • Edtech
Lead platform and infrastructure engineering to improve stability, developer productivity, CI/CD, observability, and shared libraries. Deliver platform projects, mentor engineers, own production availability and on-call, and drive platform decisions and best practices across the org.
Top Skills: AWSGithub ActionsJestMongoDBPytestPythonTerraform
Reposted 2 Months AgoSaved
Remote or Hybrid
Remote Houston, TX
170K-200K Annually
Senior level
170K-200K Annually
Senior level
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Design, develop, and deliver fullstack web solutions, optimize platforms, mentor engineers, and manage product features from ideation to launch.
Top Skills: BigQueryGraphQLPythonReactRestSQLTypescript
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
As a Staff Machine Learning Engineer, you will develop, productionize, and deploy ML models for clinical use, ensuring real-world effectiveness through hands-on coding and infrastructure building.
Top Skills: AWSMlflowPythonSagemakerSQL
Reposted 2 Months AgoSaved
In-Office or Remote
Remote Houston, TX
170K-290K Annually
Expert/Leader
170K-290K Annually
Expert/Leader
Artificial Intelligence • Software
As a Software Engineer in Reliability, you'll architect and manage multi-cloud GPU infrastructure, ensuring performance, security, and scale while debugging complex hardware/software issues.
Top Skills: AmdAWSBashGoGpuInfinibandLinuxNvidiaOciPythonRdma
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
100K-130K Annually
Senior level
100K-130K Annually
Senior level
Information Technology • Internet of Things • Software
Serve as an embedded Linux expert on customer projects: design and refactor real-time architectures, develop Linux kernel drivers, debug low-level hardware/software issues, optimize kernel performance, collaborate with customers and internal teams, lead technical efforts, produce high-quality deliverables, and create technical proposals to support product lifecycle and certification.
Top Skills: AlteraAmdArm Cortex-AAssemblyBashBuildrootCDevice DriversDmaFreescaleGitHypervisorIntelInterruptsLinux KernelNxpOpenembeddedProfilers/TracersPythonReal-Time Operating SystemsX86XilinxYocto
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Artificial Intelligence • Insurance
The Software Engineer will build features across the stack, design AI/LLM-driven workflows, translate requirements, and collaborate closely with the founding team and customers.
Top Skills: Amazon DynamodbAmazon EcsAWSAws LambdaFastapiNextjsPostgresPythonReactS3Typescript
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Artificial Intelligence • Healthtech • Information Technology • Analytics
Lead a cross-functional engineering team to design and deliver SMART on FHIR applications embedded in EMR workflows. Champion AI-driven, agent-assisted development, collaborate with data engineering on Python/dbt/SQL pipelines, implement engineering best practices, and manage hiring, mentorship, and stakeholder communication while ensuring quality, reliability, and interoperability.
Top Skills: Cds HooksClaude CodeCopilotCursorDbtEmrFhir R4Hl7 V2 (AdtLlmNext.JsOru)PythonReactSmart On FhirSmart/Oauth2SQLTypescript
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
200K-230K Annually
Senior level
200K-230K Annually
Senior level
Fintech • Software • Financial Services
The Senior Full-Stack Software Engineer will design, build, and scale backend services and APIs for financial transactions while collaborating with frontend engineers and contributing to technical design.
Top Skills: AWSDjangoPostgresPythonReactTypescript
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
135K-185K Annually
Mid level
135K-185K Annually
Mid level
Edtech
Develop and ship backend and frontend features that improve school-family communication. Collaborate with product and design, champion AI/LLM-driven workflows, build scalable secure services on AWS, evolve monolithic systems, participate in code reviews, and help shape architecture.
Top Skills: Ai AgentsAuroraAWSJavaScriptLlmsMySQLPHPPostgresPythonRdsRestful ApisRubySqsTypescript
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
176K-220K Annually
Senior level
176K-220K Annually
Senior level
Healthtech
Design, build, and operate scalable AWS-based platform infrastructure for data processing. Improve pipeline automation, monitoring, security, and reliability. Lead CI/CD, IaC (Terraform/Scalr), network design, and incident response; collaborate with cross-functional teams and participate in on-call rotation. Integrate AI tools to streamline development and troubleshooting.
Top Skills: AirflowAWSBackend ApisChatgptCidrCursorDatabricksGeminiGithub ActionsMicroservicesPythonScalrSnowflakeSubnetsTemporalTerraformVpc
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Reposted 2 Months AgoSaved
Remote or Hybrid
Remote Houston, TX
205K-265K Annually
Senior level
205K-265K Annually
Senior level
AdTech • Digital Media • eCommerce • Marketing Tech • Mobile • Software
Define and drive full-stack architecture and technical vision across teams, write high-quality production code, lead zero-to-one projects, productionize ML systems, own reliability and SLOs, mentor senior engineers, and align engineering roadmaps with product and company strategy.
Top Skills: AWSDockerGoJavaScriptNode.jsPythonReactRelational DatabasesTypescript
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
115K-210K Annually
Senior level
115K-210K Annually
Senior level
Business Intelligence • Consulting
Design, develop, and document Salesforce solutions (Apex, LWC, Visualforce) and integrations; lead small developer teams; build APIs, data migrations, and test plans; ensure code quality and mentor others while evaluating and adopting AI-enabled tools.
Top Skills: .NetAngularApexAPIsContinuous IntegrationCSSData PipelinesETLGitHTMLJavaJavaScriptJqueryLightning Web ComponentsPythonRest ApisSalesforceSalesforce PlatformSOQLSoslSQLVisualforce
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Industrial
The Senior DevOps Engineer will build secure, scalable infrastructure on AWS, manage Kubernetes platforms, and oversee FedRAMP-related tasks while ensuring compliance and operational efficiency.
Top Skills: AWSBashCi/CdGoHelmKafkaKubernetesPostgresPython
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Cloud • Security
Manage a team of cloud engineers to govern and optimize a multi-cloud environment while implementing security frameworks and managing vendor relationships.
Top Skills: AWSAzureBashIacMicrosoft EntraPowershellPythonTerraform
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Information Technology • Cryptocurrency
The Site Reliability Engineer will lead technical initiatives, architect solutions, troubleshoot issues, mentor team members, and improve observability practices.
Top Skills: ArgocdBashElk StackGCPGoGrafanaHelmKubernetesPrometheusPythonTerraform
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
Mid level
Mid level
Information Technology • Consulting
The Cloud Administrator manages cloud infrastructure and services, ensuring their performance, security, and reliability while troubleshooting issues and optimizing costs.
Top Skills: AWSAzureBashGCPPythonTerraform
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
154K-231K Annually
Senior level
154K-231K Annually
Senior level
Information Technology • Marketing Tech • Social Media
Lead technical design and architecture of large-scale Ceph clusters, drive capacity planning and major upgrades, resolve complex cross-functional production incidents, establish automation and reliability standards, and mentor engineers on advanced Ceph operations to scale the global storage platform.
Top Skills: AnsibleBluestoreCephCephfsCinderCrushCsiDdnErasure CodingGoIsilonKubernetesManilaMdsMgrMonNetappNeutronNovaOpenstackOsdPlacement GroupsPurePythonRbdRbd MirroringRgwRgw MultisiteRookS3SaltstackSwiftTerraformVastWeka
2 Months AgoSaved
In-Office or Remote
Remote Houston, TX
Senior level
Senior level
Cloud • Software • Analytics • Energy
Build and maintain Python backend services and APIs for an economics engine: design scalable time-series processing, optimize MongoDB schemas and queries, deploy containerized services on GCP, ensure testability and code quality, use AI tooling to accelerate delivery, and own features end-to-end including monitoring and documentation.
Top Skills: Agent FrameworksAsync/AwaitCloud FunctionsDockerDocker ComposeFastapiFlaskGcp (Cloud RunGcs)GrpcGunicornLlm ApisMongoDBMongoengineNumpyOpenapiPandasPymongoPyrightPytestPython 3.13+RestRuffType AnnotationsUv
2 Months AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Insurance
Lead enterprise data architecture and platform engineering efforts using Databricks Lakehouse. Design scalable cloud-native data platforms, implement medallion architectures, enable data governance and AI/ML workloads, build automation and CI/CD for Databricks, and mentor teams while collaborating with stakeholders on strategy and delivery.
Top Skills: SparkAutomated TestingAWSAzureCi/CdDatabricksDatabricks LakehouseDelta LakeFhirGoogle Cloud PlatformHedisHl7Infrastructure As CodeMedallion ArchitecturePysparkPythonSQLX12
Reposted 2 Months AgoSaved
Easy Apply
Remote or Hybrid
Remote Houston, TX
Easy Apply
115K-130K Annually
Mid level
115K-130K Annually
Mid level
Software
Build and maintain full-stack product features, backend services, APIs, data pipelines, and AI integrations to transform customer interaction data into AI-powered experiences. Collaborate with cross-functional teams to design, test, and support production systems, internal tools, and user-facing interfaces. Own ambiguous problems end-to-end and raise engineering quality across the data and AI platform.
Top Skills: AIAnalytics WorkflowsCloud PlatformsConversation IntelligenceCRMData PipelinesData SystemsDistributed SystemsEvent-Driven SystemsGoogle Cloud PlatformJavaScriptLlmsMachine LearningPythonQueuesRubyRuby On RailsTelephonyTestingTypescriptVersion ControlVirtual AgentsWorkflow Engines
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
175K-225K Annually
Senior level
175K-225K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting
Design, build, and operate reliable backend systems while mentoring engineers, participating in design discussions, and improving system performance.
Top Skills: GoKubernetesLinuxMongoDBNoSQLPostgresPythonSQL
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
180K-224K Annually
Senior level
180K-224K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting
Embedded with strategic customers, own end-to-end design, build, and production rollout of cloud infrastructure for large-scale GPU/HPC AI workloads. Build compute orchestration, platform services, onboarding sandboxes, and reliability/security tooling. Turn field learnings into reusable platform capabilities and partner with Product and Engineering to productize them.
Top Skills: Ci/CdClaude CodeCloud NetworkingCloud StorageCodexCursorDockerGoGpuHpcIamInfrastructure As CodeKubernetesObservabilityPythonRbac
Reposted 2 Months AgoSaved
Remote
Remote Houston, TX
170K-300K Annually
Senior level
170K-300K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting
The Lead Systems HPC Engineer will optimize GPU clusters' performance, troubleshoot issues, integrate new hardware, and collaborate with teams on system-level software development.
Top Skills: C/C++GoInfinibandKvmLinuxMpiNcclPythonQemuRoce
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