Top Remote Python Jobs in Houston, TX

The role involves architecting scalable backend systems for real-time evaluations, integrating with streaming data, and building intervention layers for AI applications. You'll design frameworks and operationalize vector databases while ensuring low-latency service performance.

Design and implement Infrastructure as Code and automation (Terraform, Bicep, ARM, CloudFormation). Build reusable modules, automate provisioning, and develop pipelines (Azure DevOps, GitHub Actions, Jenkins). Script in Python, PowerShell, Bash and use Ansible. Manage hybrid infrastructure across Azure, AWS, VMware and Windows Server, ensuring HA, DR, capacity planning and lifecycle. Enforce security baselines, Zero Trust, identity (Azure AD/Entra/AD), patching, vulnerability management, and compliance (SOC1/2, SOX, HIPAA, PCI, ISO27001).

The role includes leading a team of database engineers, designing and optimizing Oracle databases and AWS data services, and overseeing data migration efforts. Responsibilities involve collaboration across teams, performance tuning, and managing production support.

The Senior Enterprise Architect leads the design and implementation of network and cloud architectures, ensuring alignment with organizational goals and industry practices. Responsibilities include defining architecture frameworks, advising on cloud adoption, ensuring security compliance, and managing cross-functional teams.

Design, develop, and implement network automation solutions for GPON/XGS-PON and IP multi-vendor environments. Lead scripting (Python, Go), CI/CD pipelines, integrations, documentation, mentoring, and automation of provisioning, monitoring, and reporting to boost operational efficiency.

Lead and grow a Data Engineering organization to design, build, and operate scalable, governed data pipelines and enterprise data products. Define technical strategy and roadmap, improve data quality, reliability, observability and governance, partner with cross-functional teams, and drive platform evolution to enable analytics, ML, reporting, and self-service insights.

Design, build, and operate high-throughput distributed data pipelines and platform infrastructure. Own end-to-end systems from architecture to production, write production-grade Python, optimize SQL at scale, architect service contracts, mentor engineers, and instrument systems for observability.

Lead design, implementation, automation, and security operations for Azure cloud networking in FedRAMP High/IL4 environments. Build modular IaC (Terraform, ARM, Bicep), implement advanced networking and firewall controls, mentor team members, participate in on-call support, and translate compliance controls into enforceable guardrails.

Lead technical vision and architecture for the Mojo compiler backend: IR lowering, optimization passes, and code generation across CPUs, GPUs, and AI accelerators. Drive MLIR/LLVM initiatives, expand debugging and profiling tooling (LLDB/GDB, LSP, profilers), mentor engineers, collaborate with cross-functional teams, and engage with the open-source community to shape developer tooling and compiler strategy.

Lead design and hands-on development of AWS-based serverless backend and IoT cloud services. Build Python Lambda microservices, REST APIs, telemetry pipelines, and secure AWS IoT Core device communication. Mentor engineers, define architecture patterns, ensure production readiness (monitoring, CI/CD, security), and guide cross-functional integrations and technical roadmaps.

Lead fullstack technical work connecting Python/Django backend services with Unity (C#) client, drive technical roadmap, own live-ops reliability and incident management, mentor cross-functional teams, deliver scalable features, and reduce technical debt for a live-service mobile/PC game.

Lead backend development for MapMyFitness, collaborate with product/marketing/design, build and maintain APIs for mobile clients, respond to bugs, monitor and resolve incidents, ensure high availability, ship maintainable/testable code, and drive major architectural changes for a platform used by millions.

The role involves deploying AI networking solutions in data centers, driving architectural decisions, troubleshooting network issues, and collaborating on customer projects for NVIDIA's technology solutions.

Lead full-stack development across Superset frontend and backend services. Design and ship end-to-end features, improve performance and scalability, own major technical initiatives, mentor engineers, set engineering standards, and collaborate with product, design, and the open-source community.

Join as the company's first SRE to design reliability processes, build observability/CI/CD/IaC tooling, define SLOs, embed with product teams, run incident response, and support compliance for patient data.

Hands-on technical leader and core individual contributor building cloud-native defense/intelligence software. Drive architecture, code reviews, feature delivery, and mentor a small Agile team while implementing DevOps, CI/CD, and robust AWS/EKS-based deployments.

Build and scale a live ML data streaming analytics platform, lead greenfield real-time processing projects (Python/Rust), and design reliable backend services using cloud and orchestration tools.

Lead quality engineering within an Agile squad, design and maintain automated test suites across UI, API, microservices and DB, integrate tests into CI/CD, mentor SDETs, triage production issues, define test strategy, tooling and test environments, and enforce quality best practices.

Lead design and operation of the Synapse Everywhere external API platform: define API surface and guarantees, translate product and clinical requirements into contracts, own reliability and on-call incident response, provide technical mentorship and code reviews, and design scalable, secure cloud-native solutions (k8s, LLMs) with strong developer experience.

Design, build, and optimize scalable real-time and batch data pipeline infrastructure. Develop backend features focused on reliability and performance, write well-tested code, review technical designs, and contribute to infrastructure across mobile, desktop, and server systems.

Design, build, and operate large-scale distributed web crawlers and data pipelines. Handle anti-bot systems and dynamic/JS-heavy sites, perform cleaning, deduplication, filtering, and normalization, and maintain datasets for model training while optimizing for cost, latency, and reliability.

The Senior Site Reliability Engineer is responsible for maintaining Wikimedia's infrastructure, improving reliability, automating processes, and collaborating with teams. The role involves troubleshooting, managing deployments, and leading incident responses while working remotely.

Lead and grow a distributed senior engineering team as a player-coach, delivering shared SaaS platform services and core AI capabilities. Drive cloud-native architecture, model integration, reliability, FedRAMP compliance, AI-first engineering practices, and partner closely with Product, Security, and Platform Engineering to define roadmaps and technical standards.

Develop, maintain, and automate Twilio's Compute cloud infrastructure including scalable cloud-native environments, VM orchestration, hardened AMIs, ASG/EC2 management, container images, and OS libraries. Collaborate with architects and engineers, produce IaC-compliant implementations, author documentation and runbooks, participate in on-call rotation, and support legacy and new platform components using automation and best practices.

Design, implement, and manage scalable cloud infrastructure (AWS/Azure/GCP); build and maintain CI/CD pipelines; automate provisioning with Terraform/Ansible; run containerized workloads with Docker and Kubernetes; implement monitoring and alerting (Prometheus, Grafana, ELK); enforce cloud security best practices; collaborate with development teams to optimize deployment, reliability, and performance.