Top Remote Python Jobs in Houston, TX

Lead architecture and development of secure, high-scale Python and FastAPI payment infrastructure for AI-agent transactions. Design APIs for tokenization, mandates, authentication, attestation, and cryptogram workflows; own security, reliability, observability, testing, Kubernetes provisioning, and production operations. Drive technical initiatives, design reviews, and cross-functional collaboration with product, security, infrastructure, platform, and card-network partners while applying AI-assisted engineering practices.

Serves as the strategic architect and technical lead for enterprise observability, APM, telemetry, and SRE ecosystems. Designs unified monitoring across hybrid cloud, Kubernetes, and legacy environments; establishes SLOs, SLIs, error budgets, and incident-response practices; leads automation using Ansible, Terraform, Python, and GitOps; and develops secure, scalable telemetry pipelines. The role also leads FOAK implementations, monitoring migrations, vendor transitions, knowledge-transfer programs, major incident escalations, operational handoffs, and engineering-team mentoring.

Leads major technical initiatives while designing enterprise identity systems, authorization models, and scalable multi-tenant SaaS architecture. Builds platform components with .NET/C# on AWS, improves data pipelines, resolves complex production issues, and shapes the technical roadmap. Mentors engineers, drives architecture and reviews, coordinates across teams, and supports security, compliance, automation, and continuous platform improvement.

Build full-stack Django applications with a frontend focus, creating intuitive, interactive, and performant data visualizations for complex healthcare pricing data. Collaborate with product and engineering teams to define user experiences, prioritize features, write scalable code, test and debug systems, improve existing functionality, and translate user requirements into technical solutions.

Design and scale reliable spine-leaf data center networks supporting GPU clusters and AI workloads. Build Ethernet fabrics using EVPN/VXLAN and BGP, optimize traffic, support RoCE/RDMA, and manage backbone, WAN, DCI, and edge connectivity. Develop network automation and Infrastructure-as-Code solutions, improve observability and telemetry, troubleshoot distributed performance issues, and collaborate with compute, storage, platform, and operations teams. The role requires hands-on Cumulus NOS expertise and experience with large-scale, high-performance infrastructure.

Build and maintain a React/TypeScript operations portal and Supabase/PostgreSQL backend for autonomous aircraft medical logistics. Improve aircraft allocation, mission generation, telemetry ingestion, live dashboards, reliability, testing, logging, and observability. Integrate Python services with ArduPilot aircraft and simulations while collaborating with autonomy and simulation engineers to mature real-flight and digital-twin systems.

Supports the design, prototyping, assembly, testing, repair, simulation, and flight testing of autonomous aircraft. Interns may work across airframe and mechanical design, avionics, controls, manufacturing, and data review while owning a project that improves aircraft development.

Design, deploy, enhance, and support secure custom government network platforms and cloud services. Manage CI/CD pipelines, build systems, testing frameworks, distributed databases, and storage ecosystems. Lead technical initiatives, code reviews, security patching, Agile SDLC releases, and system performance improvements. Collaborate with Operations, Engineering, and SRE teams to troubleshoot complex issues and deliver resilient application delivery networks.

Designs, troubleshoots, tests, and supports data center networking solutions for customers. Serves as a Juniper and HPE networking subject matter expert, providing break/fix support, Junos configuration guidance, network architecture, automation, documentation, and best-practice recommendations. The role evaluates designs, supports cross-organizational projects, drives technology innovation, manages technical relationships, and mentors junior engineers. Requires hands-on experience with Juniper platforms, Python automation, Junos software testing, and advanced networking certifications.

Serve as the senior technical contact for OEM Federal deployments of NVIDIA GPU-accelerated platforms. Own customer issues end to end, including troubleshooting, failure analysis, RMA procedures, root-cause investigation, and coordination with OEM support and NVIDIA engineering. Support secure Federal environments such as FedRAMP, IL5/IL6, and air-gapped SCIF facilities while maintaining sanitization and chain-of-custody requirements. Analyze multi-GPU systems, firmware, operating systems, networking, storage, and distributed workloads, with up to 35% travel.

Build and maintain enterprise web applications, APIs, and containerized microservices using Python and Django. Develop workflow engines, financial validation logic, relational database schemas, asynchronous integrations, role-based access controls, and CI/CD automation. Support complementary applications across multiple technology stacks while maintaining secure, auditable, and reliable systems.

Develops, tests, documents, enhances, and maintains software solutions using Appian and related technologies. The role includes application development, process modeling, system integration, security remediation, performance improvement, user story analysis, technical documentation, and collaboration within an Agile software development team.

Develops, tests, documents, enhances, and maintains software solutions using Appian and related technologies. Designs integrations with external systems, resolves technical issues, remediates security vulnerabilities, improves performance, participates in requirements analysis and Agile development processes, and documents standards. The role also contributes to planning, mentors other engineers, collaborates with team members, and stays current with software development practices and technologies.

Lead customer migrations from self-managed GitLab to GitLab Dedicated using GitLab Geo. Plan replication, cutovers, network connectivity, and post-migration validation while debugging synchronization issues. Build repeatable automation, runbooks, and infrastructure validation using Terraform, Ansible, Kubernetes, and cloud platforms. Manage multiple customer engagements, advise stakeholders, communicate technical plans, and collaborate with Professional Services, Product, and Engineering teams.

Provide technical leadership for structural and/or thermal-fluids analysis of aerospace vehicles and propulsion systems. Perform FEA, fatigue, fracture, thermal-stress, CFD, and 1D fluid modeling; validate models against test data; support loads development, anomaly investigations, and nonconforming hardware disposition. Collaborate with design, systems, manufacturing, and test teams while improving analysis methods, mentoring engineers, and supporting safety-critical aerospace systems.

Maintains and secures enterprise end-user computing environments across Windows, macOS, Android, and iOS. Responsibilities include endpoint configuration, vulnerability patching, software packaging, virtual desktop administration, policy management, troubleshooting, documentation, hardware standards, automation, root cause analysis, vendor coordination, and support rotation participation.

Develop and operate Arista’s FedRAMP CloudVision SaaS platform at scale. Responsibilities include improving reliability, scalability, observability, autoscaling, disaster recovery, capacity planning, CI/CD, network architecture, cost optimization, and cloud application security. The role develops and manages Kubernetes-native services, distributed databases, and automation using technologies such as GCP, GKE, Go, Python, Ansible, Pulumi, and Bash. Participation in a FedRAMP on-call rotation is required.

Build and operate secure, scalable Azure infrastructure and AI platform capabilities using Terraform, MCP servers, LLMOps/GenAIOps, Docker, Kubernetes, and GitHub Actions. Own CI/CD, observability, reliability, security, compliance, incident response, and production support for platform and AI workloads. Partner on AI platform roadmap development, reusable engineering patterns, tooling adoption, documentation, and Agile delivery while participating in on-call rotations.

Design, build, operate, and maintain high-scale distributed telemetry systems for Grafana Mimir. Deliver features from concept through production, improve reliability and performance, review code and designs, manage releases, collaborate across the squad, contribute to open-source projects, and participate in follow-the-sun on-call rotations. The role involves cloud software development, microservices, observability, DevOps practices, and database query optimization.

Develop and maintain automated test scripts with guidance from senior automation team members. Create and execute test cases, plans, and scenarios based on requirements. Alternate between manual validation and automation according to delivery needs. Build expertise in automation frameworks, scripting, CI/CD, and quality engineering practices while collaborating effectively with cross-functional teams in a remote environment.

Designs, implements, and manages enterprise SD-WAN, SASE, secure remote access, cloud networking, and UCaaS solutions. Leads network transformation projects, supports Cato, Fortinet, Versa, and Cisco Meraki platforms, mentors engineers, provides advanced technical escalation, develops automation, documents solutions, and helps maintain client uptime SLAs. The role also performs network assessments, implements Zero Trust architectures, troubleshoots complex environments, and collaborates directly with clients and managed-services teams.

Leads the architecture, development, and evolution of enterprise BI and analytics solutions for healthcare coding and clinical data products. Designs data, semantic, cloud, and distributed-system architectures; builds scalable data pipelines and embedded analytics; establishes engineering standards and governance; evaluates technologies and mentors development teams. The role requires extensive software engineering and architecture experience across AWS or Azure, analytics platforms, data modeling, ETL, security, reliability, and large-scale data processing.

Build and maintain full-stack donor-facing giving forms, campaign tools, administrative features, and payment flows across Stripe, ACH, and digital wallets. Own features from technical design through deployment, testing, and production support. Collaborate with product, design, and engineering partners in an Agile environment, contribute to code quality and team initiatives, and participate in rotational support and on-call coverage.

Designs and operates enterprise observability, monitoring, telemetry, and automation solutions across infrastructure, applications, IoT platforms, and cloud environments. Responsibilities include managing Grafana and Instana ecosystems, dashboards, alerts, telemetry pipelines, incidents, RCA, databases, and platform health. Automates provisioning, monitoring deployment, remediation, and operational workflows using Python, PowerShell, Bash, Ansible, and Puppet. Supports 24x7 operations, major incidents, ITIL processes, service onboarding, documentation, and cross-functional reliability initiatives.

Own and improve Snowflake platform operations across development, test, and production environments. Responsibilities include security and access governance, reliability engineering, monitoring, incident response, recovery procedures, consumption and cost optimization, change management, automated testing, and controlled releases. The role partners with Data Engineering, Security, Identity, AWS, and commercial technology teams while documenting processes and building reusable automation.