Top Machine Learning Jobs in Louisville, KY

This is an open talent‑community posting inviting U.S.-based candidates across multiple disciplines (software, AI/ML, XR, UX/UI, DevOps, cybersecurity, data, instructional design, etc.) to submit a resume and brief introduction. HTX Labs will retain candidate information for future contract-to-hire opportunities. Must be authorized to work in the U.S.; no visa sponsorship available. Remote-first role supporting immersive learning for Department of Defense clients.

Drive Midwest SLED revenue by selling analytics-driven SaaS identity and fraud solutions. Build pipeline, manage full sales cycle, develop partnerships/channels, collaborate with product, forecast accurately, and travel up to 50% to close deals and ensure customer success.

Lead portfolio-level Data & AI strategy and technical governance for enterprise clients. Advise C-suite, drive architecture and modern data stacks, win high-value engagements, and scale engineering and data science teams.

Join Trexquant as a Global Alpha Researcher to develop trading signals, implement research, and apply machine learning for alpha discovery.

Lead execution of Product Engineering AI and automation initiatives across photonics products. Build and deploy reusable AI/automation tools, transform engineering data into AI-ready systems, and drive cross-functional adoption to improve development, qualification, manufacturing, and reliability processes.

Set the technical direction for machine learning at Payabli by maturing production risk models and launching new models across the payments lifecycle. Establish experimentation, monitoring, drift detection, benchmarking, retraining, and incident-response foundations. Translate payments challenges into modeling opportunities, connect model performance to business outcomes, influence the ML roadmap, and mentor engineers while partnering with product, engineering, and risk operations.

Design, train, and productionize underwriting ML models for real-time transaction decisions. Build feature pipelines and training datasets, run experiments, integrate models into batch/real-time systems, and monitor data and model health while collaborating with cross-functional teams.

Lead a consortium advancing AI-driven neurodegeneration research: set strategy, build partnerships, manage multidisciplinary executive team, oversee product development and deployment, secure funding, ensure ethical AI and scientific integrity, and scale the platform to broader biomedical domains.

Work with enterprise customers to identify high-value tabular ML use cases, design production-grade architectures, prototype solutions, lead deployments, coordinate cross-functional teams, and codify reusable deployment patterns to scale adoption of the NEXUS tabular foundation model.

The AI Engineer will design and build production systems, focusing on LLM integration, system reliability, evaluation frameworks, and high-quality product features while maintaining strong engineering practices.

As a Principal Product Manager, you'll lead product strategy, collaborate across teams, utilize data for decision-making, and partner with top executives to drive product success.

Lead end-to-end delivery of LOIS by owning the master program plan, coordinating cross-functional teams (engineering, product, design, ML, data, SRE, operations), resolving blockers and dependencies, establishing lightweight delivery infrastructure and tooling, partnering on release planning, and maintaining transparent status, risks, and accountability to deliver complex features to customers.

This role involves leading a perception team in developing algorithms for autonomous driving systems, supervising team members, and conducting research to enhance perception capabilities.

The Data & Analytics team at Surescripts transforms healthcare data into actionable insights, collaborating with various stakeholders to support critical decisions across the healthcare ecosystem.

Lead Tekmetric's API product strategy and roadmap for the SaaS platform. Own API lifecycle (contracts, versioning, documentation), drive developer experience and adoption, identify integration opportunities, lead generative AI initiatives, perform user research and analytics-driven prioritization, collaborate across design/engineering/sales, train internal teams, and measure business impact.

Lead development of Vanta's business analytics function: build scalable product data assets, define measurement frameworks, use AI-assisted analytics, partner with cross-functional teams, and deliver executive-level recommendations to drive product and business decisions.

Design, build, and operate core AI capabilities and reusable model integrations for an enterprise platform. Integrate foundation models into production, optimize performance and reliability, prototype new techniques, and support scalable backend services and distributed AI systems in collaboration with cross-functional teams.

The role involves designing and developing model evaluation pipelines, user studies for subjective evaluations, and automated dashboards to report results, alongside leading the evaluation team and communicating with other teams to improve model performance.

Work on-site with portfolio companies to design, prototype, and deliver full-stack digital and AI solutions. Lead discovery, deployment, and post-launch iteration, ensure security/compliance, resolve technical issues, mentor teams, and drive enterprise integrations and adoption. Frequent domestic travel and stakeholder management required.

Sell Litify's AI-driven legal operating platform to law firms and legal departments. Manage full upsell motions, consult on AI adoption, deliver high-level demos to C-suite, meet sales targets, and articulate ROI of autonomous agents and AI integrations.

Lead and mature Omada's enterprise privacy program, manage HIPAA compliance and incident response, embed privacy-by-design across products, conduct privacy risk assessments and vendor due diligence, advise on consumer privacy and AI governance, support interoperability/HIE participation, and deliver privacy training and guidance across the business.

The Staff Machine Learning Engineer will lead ML systems development for personalization and ranking, design architectures, and mentor team members, ensuring reliable operations at scale.

The Machine Learning Engineer will work on unstructured data classification and clustering, utilizing their expertise in AI systems and various programming languages.

The Senior Machine Learning Engineer will utilize deep experience and insights to enhance communication and digital interactions through advanced machine learning tools and algorithms, focusing on unstructured data.

Design and build scalable data engineering and AI agent governance capabilities across major cloud AI platforms. Develop ingestion, processing, ETL, observability, security, lifecycle management, and identity governance features. Evaluate emerging AI agent frameworks and interoperability standards, troubleshoot customer issues, document architecture and processes, and collaborate with engineering, security, compliance, product, and support teams. The role also involves improving distributed data systems, mentoring engineers, and leading technical initiatives.