Top Senior Machine Learning Jobs in Louisville, KY

Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Healthtech
Lead and build a data science organization to create a prediction engine for vendor matching, order routing, and supply chain optimization. Anchor projects to P&L, design measurement and experiment frameworks, ship rapid wins, hire and coach data scientists, work hands-on in modeling and technical design, partner with product and engineering (Snowflake), and evolve systems toward agentic AI while reporting impact in dollar terms.
Top Skills: Agentic AiCausal InferenceGitMachine LearningOperations ResearchPythonReinforcement LearningSnowflakeSQL
Reposted One Month AgoSaved
Remote
Louisville, KY
210K-250K Annually
Senior level
210K-250K Annually
Senior level
Artificial Intelligence • Insurance • Software • Automation
The Staff Product Manager will define product strategy, lead the product lifecycle, collaborate across teams, and drive innovation in claims processing software.
Top Skills: Data AnalysisMachine LearningProduct ManagementSoftware Development
Reposted One Month AgoSaved
Remote
Louisville, KY
165K-250K Annually
Senior level
165K-250K Annually
Senior level
Automotive • Machine Learning • Robotics • Software • Transportation
The Director of System Safety oversees safety functions for autonomous vehicles, managing safety cases, deployment plans, and regulatory relationships while leading a multi-disciplinary safety team.
Top Skills: Iso 21448Iso 26262Iso 8800Machine LearningMl-Aware Safety AnalysisMulti-Policy Decision Making (Mpdm)Safety Management Systems
Reposted One Month AgoSaved
Remote or Hybrid
Louisville, KY
Senior level
Senior level
Information Technology • Database • Consulting
Lead development of time-series and econometric models (ARIMA, VAR, state-space, WLS, panel data) and Bayesian probabilistic frameworks. Use causal inference and stochastic processes to produce actionable insights, work with large datasets on Databricks, communicate results to stakeholders, and mentor junior team members.
Top Skills: A/B TestingArimaBayesian ModelingCausal InferenceDatabricksMachine LearningMarkov ChainsMlopsPanel Data ModelsPythonSarimaSQLState-Space ModelsStochastic ProcessesVarWls
Reposted One Month AgoSaved
Remote
Louisville, KY
190K-220K Annually
Senior level
190K-220K Annually
Senior level
Edtech
Own a product area of the Content Authoring Platform end-to-end: set vision and roadmap, run continuous discovery, define and measure outcomes, partner with engineering and design to deliver features, evaluate and apply AI capabilities prudently, mentor peers, and communicate strategy and trade-offs to stakeholders.
Top Skills: APIsAuthoring ToolsContent Management SystemsGenerative AiMachine LearningMl-Assisted WorkflowsNlpPrompt EngineeringRecommendation Systems
Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Software
Lead client-facing full-stack Java development, mentor teams, design solutions, promote engineering best practices (Agile, DevOps, CI/CD, TDD), and deliver enterprise software using modern cloud, container, and JS frameworks.
Top Skills: AIAngularAWSAzureBootstrapCi/CdCoderpadDevOpsDockerGitGitGoogle Cloud PlatformGradleIotJavaJavaScriptJenkinsKafkaKubernetesMachine LearningMavenReactSpring BootSQLTddTest Automation
One Month AgoSaved
Remote
Louisville, KY
150K-185K Annually
Senior level
150K-185K Annually
Senior level
Agency • Digital Media • Consulting
Build and maintain full-stack features, data pipelines, and cloud infrastructure for large-scale ad management and analytics. Integrate with advertising platform APIs, apply ML/NLP for forecasting and recommendations, collaborate with product and marketing teams, and use AI coding tools to accelerate development.
Top Skills: AWSAzureBig Data PipelinesClaude CodeContainerizationDockerGCPGithub CopilotGoogle Ads ApiMachine LearningMeta/Facebook Ads ApiNlpPythonSQLTiktok Ads ApiVue
One Month AgoSaved
Remote
Louisville, KY
179K-210K Annually
Senior level
179K-210K Annually
Senior level
Real Estate • Travel • PropTech
Lead causal inference and measurement efforts for payments, build and evaluate ML/AI and LLM-based models, optimize fraud mitigation and loss strategies, simulate interventions, and communicate findings to stakeholders to drive product and risk decisions.
Top Skills: LlmMachine LearningPythonRSQL
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
Senior level
Senior level
Software • Cryptocurrency • Web3
Own end-to-end analysis of payments, chargebacks, and user lifecycle to identify drivers of net loss. Deep-dive into fraud cases, design and evaluate A/B experiments and risk-rule changes, build monitoring dashboards, partner with Risk, Payments, and Product to convert insights into mitigations, and run ad-hoc analyses of emerging loss trends.
Top Skills: AchCardMachine LearningPythonRSQL
Reposted One Month AgoSaved
Remote
Louisville, KY
131K-180K Annually
Senior level
131K-180K Annually
Senior level
Biotech
Lead and execute independent research programs on NLP and LLM safety, design and run experiments, secure funding, publish and present results, lead cross-functional teams, and develop evaluation tools and challenges to advance digital safety.
Top Skills: AIData AnalysisExperimental DesignLarge Language Models (Llms)Machine LearningNatural Language Processing (Nlp)
One Month AgoSaved
Remote
Louisville, KY
164K-191K Annually
Senior level
164K-191K Annually
Senior level
Real Estate • Travel • PropTech
Lead analytics partner to Community Support, driving data-driven roadmaps, scalable reporting and measurement, causal inference and experimentation, and improvements to agent/guest/host experiences via analytics, modeling, and stakeholder influence.
Top Skills: AirflowETLMachine LearningPythonRSQL
One Month AgoSaved
Remote or Hybrid
Louisville, KY
170K-200K Annually
Senior level
170K-200K Annually
Senior level
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Design and implement scalable backend and distributed systems for a marketing intelligence platform. Build near-real-time ingestion and processing, scale an incrementality/experimentation product, integrate AI-powered workflows, improve data ingestion/exports and connection-state systems, and contribute frontend components to deliver end-to-end product experiences.
Top Skills: AIAPIsData ProcessingDistributed SystemsMachine LearningMicroservicesPythonRbacReactReal-Time Data IngestionTypescript
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One Month AgoSaved
Remote
Louisville, KY
190K-240K Annually
Senior level
190K-240K Annually
Senior level
Big Data • HR Tech • Mobile • Software • Database
Lead a Big Data Engineering team to deliver production-grade ETL and data pipelines at scale. Own team execution, code quality, morale, and roadmap execution with product managers. Remove roadblocks, coach and develop engineers, promote engineering best practices, and enable data-driven and AI-powered product features (personalization, recommendations, search, ranking, matching).
Top Skills: AIBig DataData PipelinesETLMachine Learning
Reposted One Month AgoSaved
Remote
Louisville, KY
60-90 Hourly
Senior level
60-90 Hourly
Senior level
Artificial Intelligence • HR Tech • Professional Services • Software
Evaluate and strengthen AI model behavior on cybersecurity topics by writing expert prompts, annotating and grading model responses for accuracy and safety, and applying structured guidelines to classify sensitive content. Work part-time on AI safety tasks with emphasis on secure, responsible handling of dual-use information.
Top Skills: AICybersecurityMachine LearningPrompt Engineering
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
Senior level
Senior level
Industrial • Manufacturing
Lead manufacturing process improvements for precision optical production: analyze data, reduce cycle time and costs, design/qualify tooling and automation, apply Lean/Six Sigma and AI-enabled analytics, maintain process documentation, partner cross-functionally, drive CAPEX and continuous improvement projects, and train production staff.
Top Skills: Ai-Enabled AnalyticsAutomationData AcquisitionDoeErpFmeaMachine LearningMachine VisionMS OfficeMrpOeePfmeaRoboticsSpc
Reposted One Month AgoSaved
Remote
Louisville, KY
100K-100K Annually
Senior level
100K-100K Annually
Senior level
Artificial Intelligence • Machine Learning • Database
Seeking a Senior Full Stack .NET Developer to work on a social good project, with strong skills in C#, AngularJS, design, and UX. Requires 5+ years of experience.
Top Skills: .NetAngularAngularjsC#Machine LearningPython
Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
The Senior Data Scientist will design and deploy time-series forecasting models, collaborate with stakeholders, and operationalize models in cloud environments, focusing on demand planning across various industries.
Top Skills: AIArimaAzureData ScienceDemand ForecastingEtsGbmLightgbmMachine LearningPythonRandom ForestSarimaSQLTime-Series ModelingXgboost
One Month AgoSaved
Remote
Louisville, KY
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
Drive Midwest SLED revenue by selling analytics-driven SaaS identity and fraud solutions. Build pipeline, manage full sales cycle, develop partnerships/channels, collaborate with product, forecast accurately, and travel up to 50% to close deals and ensure customer success.
Top Skills: Big DataData AnalyticsFraud DetectionIdentity VerificationMachine LearningSaaSSecurity
One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Angel or VC Firm • Automotive • Transportation
Lead end-to-end deployments of AI for hotel revenue teams: integrate PMS/CRS/RMS, ship ML/optimization models and agentic workflows, validate recommendations with revenue managers, define metrics, drive adoption, and hire/mentor the forward deployed engineering team.
Top Skills: Agentic AiAmadeus AcrsAmadeus BiAWSAzureDuettoGCPHtngIdeasKalibriLighthouseMachine LearningModel Context Protocol (Mcp)Opentravel Alliance (Ota)Optimization ToolingOracle Hospitality Integration Platform (Ohip)Oracle OperaPythonRagRevenue AnalyticsSabre SynxisSQLStrUniversal Commerce Protocol (Ucp)
One Month AgoSaved
Remote
Louisville, KY
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Healthtech • Software
Lead strategy, roadmap, and lifecycle for payer analytics and automation products. Translate market, customer, regulatory, and data insights into product requirements, drive cross-functional delivery with Engineering and Data Science, support go-to-market and adoption, and measure product performance to inform investment and portfolio decisions. Build product practices and partner with stakeholders across sales, customer success, clinical, actuarial, and executive teams.
Top Skills: AIClinical DataCloud-NativeDashboardsEmbedded AnalyticsHealthcare Claims DataInteroperabilityMachine LearningPharmacy DataPredictive AnalyticsSaaS
One Month AgoSaved
In-Office or Remote
Louisville, KY
Senior level
Senior level
Software
Lead execution of Product Engineering AI and automation initiatives across photonics products. Build and deploy reusable AI/automation tools, transform engineering data into AI-ready systems, and drive cross-functional adoption to improve development, qualification, manufacturing, and reliability processes.
Top Skills: AIAnalyticsAsicDecision-Support ToolsDspKnowledge ManagementMachine LearningOptical TransceiversPhotonicsPythonSemiconductor TechnologiesTraceability SystemsTrosa
27 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Fintech • Information Technology • Payments • Financial Services
Set the technical direction for machine learning at Payabli by maturing production risk models and launching new models across the payments lifecycle. Establish experimentation, monitoring, drift detection, benchmarking, retraining, and incident-response foundations. Translate payments challenges into modeling opportunities, connect model performance to business outcomes, influence the ML roadmap, and mentor engineers while partnering with product, engineering, and risk operations.
Top Skills: Amazon SagemakerAWSDrift DetectionFeature StoresInference PipelinesMlopsModel MonitoringTraining Pipelines
Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Edtech • Information Technology • Biotech
Lead a consortium advancing AI-driven neurodegeneration research: set strategy, build partnerships, manage multidisciplinary executive team, oversee product development and deployment, secure funding, ensure ethical AI and scientific integrity, and scale the platform to broader biomedical domains.
Top Skills: AIData GovernanceFederated Data ArchitecturesMachine LearningPrivacy-Preserving Technologies
Reposted One Month AgoSaved
Remote
Louisville, KY
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Information Technology • Productivity • Software
The AI Engineer will design and build production systems, focusing on LLM integration, system reliability, evaluation frameworks, and high-quality product features while maintaining strong engineering practices.
Top Skills: Large Language ModelsMachine LearningObservabilityRetrieval Augmented GenerationSemantic SearchVector Databases
Reposted One Month AgoSaved
Remote
Louisville, KY
150K-165K Annually
Senior level
150K-165K Annually
Senior level
Legal Tech • Software
Lead end-to-end delivery of LOIS by owning the master program plan, coordinating cross-functional teams (engineering, product, design, ML, data, SRE, operations), resolving blockers and dependencies, establishing lightweight delivery infrastructure and tooling, partnering on release planning, and maintaining transparent status, risks, and accountability to deliver complex features to customers.
Top Skills: APIsData PipelinesData ScienceJIRALinearLlmMachine Learning
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