Top Senior IT Jobs in Greensboro, NC

Manages Pulmovant’s enterprise application portfolio, including validated GxP and clinical systems and core IT platforms. Oversees system performance, configuration, compliance, access, documentation, integrations, upgrades, and validation. Partners with Clinical, Regulatory, Quality, Finance, and HR stakeholders, manages vendors and an applications team, and leads continuous improvement, root-cause analysis, and application initiatives. The role also supports AI and machine learning governance, model validation, and responsible data practices.

Owns the vision, strategy, roadmap, feature definition, release planning, and performance measurement for IT clinical solution products. Partners with business and technical stakeholders on build-versus-buy decisions, architecture, licensing, change management, KPIs, ROI, migration, risk mitigation, and product adoption. Coordinates cross-functional delivery and vendor relationships while adapting product direction to changing business needs.

Own end-to-end IT support and administration across identity, collaboration, AI, endpoint, and email platforms. Build AI-assisted triage, self-service, and agentic workflows; manage Claude Enterprise and MCP connectors; administer Jamf and Intune fleets; support onboarding and offboarding automation; oversee access reviews, MFA, phishing reports, and basic incident triage. The role requires strong judgment about automation versus human support, cross-functional ownership, and clear, personal communication.

Designs and leads secure, scalable enterprise software architectures and cloud modernization initiatives. The role establishes engineering standards, mentors development teams, and architects platforms using AWS, Kubernetes, microservices, and serverless technologies. Responsibilities include developing AI agents and AI-assisted engineering practices, building Databricks data integration solutions, and implementing identity and access solutions with OAuth2, OIDC, SAML, Okta, and Keycloak. The position is fully remote, requires U.S. citizenship and Public Trust eligibility, and involves less than 10% travel.

Administers, configures, secures, and optimizes Databricks workspaces across development, test, and production environments. Manages clusters, jobs, workflows, access controls, governance, monitoring, troubleshooting, backups, and cost optimization. Automates provisioning and policy enforcement through infrastructure as code and integrates Databricks with CI/CD pipelines. Provides Tier 2/3 support, documentation, user training, and technical guidance to data engineering, analytics, and data science teams.

Provides production database administration and support for mission-critical environments, including performance monitoring, incident response, root-cause analysis, security, and availability. Develops SQL Server database objects, ETL pipelines, dimensional models, data marts, dashboards, and Splunk monitoring solutions. Designs cloud and hybrid database architectures, performs data migrations, validates data integrity, and collaborates with stakeholders on technical requirements and analytics solutions within an Agile environment.

Owns IT systems administration and security operations for a fully remote workforce. Responsibilities include managing Microsoft 365 and Google Workspace, endpoint and identity platforms, security tools, access controls, threat monitoring, incident response, vulnerability management, compliance evidence, disaster recovery, vendor relationships, reporting, and operational roadmaps.

Leads the strategic direction of backend and full-stack engineering, architects scalable distributed systems and microservices, and drives modernization, reliability, security, and performance initiatives. Designs APIs, data architectures, pipelines, infrastructure, and observability practices; delivers customer-facing service improvements; establishes engineering standards; and mentors engineers. Collaborates across product and technical teams to make architecture and business trade-offs and lead large-scale initiatives from vision through production.

Creates and maintains program reports, supports ePMO operations, troubleshoots ServiceNow issues, assists with reporting migrations, and identifies milestones, risks, and project events. The role facilitates schedule reviews, maintains program records, documents lessons learned, and collaborates with technical and nontechnical stakeholders. It requires experience with ServiceNow, ePMO or similar platforms, cloud solutions, requirements analysis, risk management, and federal program support.

The Lead Technical Support Engineer resolves complex technical issues, provides mentorship, collaborates with teams, and improves support systems.

Leads IT integration projects for acquired businesses, managing requirements, scopes, vendor SOWs, development, QA, testing, cutover, communications, training, and project tracking. Oversees the IT Specialist and Salesforce Administrator while coordinating with legal, business development, developers, vendors, and cross-functional stakeholders. Requires strong project management, communication, analytical, multitasking, and Agile/Scrum skills.

Own Flex’s IT and corporate security function as a hands-on senior individual contributor. Responsibilities include identity and access management, joiner-mover-leaver processes, Okta and Google Workspace administration, endpoint and MDM programs, SaaS governance, access reviews, security policies, awareness training, MSP management, and automation using scripts and internal tooling. The role partners with security, People, Finance, and Legal while maintaining corporate security posture across a distributed workforce.

Partners with finance and IT stakeholders to define business needs, configure and support JDE and SaaS field service systems, manage ERP integrations, design reports and data conversions, test solutions, provide production support, document processes, train users, and lead IT initiatives within the Project Controls portfolio.

Leads strategy, solutioning, and writing for complex federal proposals valued at $25M to $1B+. Shapes win themes, ensures compliance, identifies risks, partners with capture and solution teams, improves proposal operations, and mentors proposal staff. Supports multiple pursuits, large IDIQs, task orders, and AI-enabled proposal workflows while tailoring technical and management volumes to customer priorities and evaluation criteria.

Performs IT-focused Internal Control over Financial Reporting and SOX testing, including IT general controls, access, segregation of duties, and program change controls. Leads control walkthroughs, evaluates technical evidence, documents findings, tracks remediation, and coordinates with management and external auditors. Uses Alteryx, AI, and automation to improve testing efficiency. Advises process owners on control design and supports internal audit, compliance, reporting, and continuous improvement initiatives.

Partners with IT hiring managers to develop talent acquisition strategies, source and screen candidates, build diverse pipelines, and present qualified talent. Provides recruiting consultation, interview guidance, offer support, vendor coordination, TA systems maintenance, reporting, and special-project leadership. Helps maintain recruiting policies, procedures, communications, and organizational talent acquisition programs while mentoring colleagues and promoting Navitus’ employment brand.

Senior Agile Business Analyst supporting a federal case management modernization program. Responsibilities include backlog decomposition, requirements elicitation, user story development, process mapping, customer journey mapping, acceptance criteria, validation, risk management, Agile ceremonies, and collaboration with Product Owners, architects, testers, developers, and court stakeholders. The role also supports testing, business process re-engineering, technical documentation, cloud solution implementation, and continuous process improvement.

Lead the design and operation of a cloud-first IT environment, including SaaS administration, endpoint management, security, automation, email platforms, and AI-powered workflow agents. The role drives cross-functional IT projects, mentors team members, maintains standards and documentation, resolves complex escalations, and supports onboarding and escalated tickets. Key responsibilities include managing Google Workspace, Proofpoint, Slack, Okta, Jamf, Intune, and related systems while improving reliability, security, and operational efficiency.

Develops, tests, deploys, and maintains enterprise applications using Microsoft .NET technologies, SQL Server, REST/SOAP services, and modern web tools. Participates in SAFe Agile Scrum ceremonies, CI/CD automation, DevSecOps, secure coding, testing, code reviews, vulnerability remediation, troubleshooting, and application modernization. Collaborates with product owners, developers, testers, stakeholders, and technical teams while supporting documentation, production operations, and software lifecycle delivery for Department of Veterans Affairs systems.

Manages and optimizes procurement operations, Coupa workflows, supplier onboarding, purchase orders, invoices, and procurement integrations. Maps and improves business processes, implements ITGC-compliant changes, leads testing and sign-off, develops spend and supplier performance reporting, and resolves invoice and purchase order discrepancies. Drives Coupa Supplier Portal, CXML onboarding, and e-invoicing adoption while partnering with finance, accounts payable, stakeholders, suppliers, and Coupa support.

The Senior IT Security Engineer strengthens cybersecurity across architecture reviews, AI and emerging technology assessments, IAM governance, vulnerability management, third-party risk, security assurance, incident response, phishing simulations, automation, and regulatory compliance. The role validates security controls, supports remediation, develops risk metrics and reporting, oversees identity platforms, and partners with technology, business, audit, compliance, procurement, and vendors in a regulated banking environment.

Leads secure, reliable IT infrastructure supporting distributed clinical research sites and remote employees. Manages enterprise networking, Azure and Microsoft 365 services, endpoint platforms, automation, AI-enabled operations, vendors, budgets, and technology projects. Oversees site deployments, security and compliance initiatives, service delivery, and operational improvements while recruiting, coaching, and developing technical teams.

Evaluates IT infrastructure, applications, cybersecurity, compliance, costs, scalability, and compatibility during mergers and acquisitions. Leads technology integration and separation planning, identifies modernization and consolidation opportunities, conducts IT capability and maturity assessments, recommends governance frameworks, and aligns technology strategy with business objectives. The role also prepares diligence reports and executive presentations while collaborating with internal and external stakeholders in fast-paced transaction environments.

Provides application and system support, troubleshoots issues, manages testing and deployments, develops ETL tools and reports, and conducts business analysis. The role defines requirements, identifies IT solutions, supports system integrations, documents procedures, guides team members, and communicates with stakeholders. It also applies agile practices and supports process improvements within a financial services environment.

Leads IT governance, risk, and compliance activities, including SOC 2 readiness, audit planning and execution, policy development, control assessments, evidence gathering, remediation tracking, and regulatory research. Partners with auditors, control owners, IT leadership, and GRC team members to maintain compliance with NIST CSF and financial services regulations. Provides guidance on audit and policy matters while improving GRC processes and tooling.