Top Senior Software Engineer Jobs in Charleston, SC

Build and scale Xbox growth experiences across console, web, and mobile through full-stack engineering and data-driven experimentation. Responsibilities include proposing product hypotheses, designing A/B tests, implementing telemetry and analytics, shipping reliable services and client features, analyzing results, participating in on-call rotation, using AI-enhanced workflows, mentoring engineers, and driving experiments that improve retention and daily active users.

Lead hands-on full-stack development for Ruby on Rails, TypeScript, and React applications. Shape technical direction, design reliable APIs and data flows, optimize relational database performance, and deliver responsive front-end experiences. Lead projects end to end, mentor engineers, review and refactor code, collaborate cross-functionally, and explore AI-assisted engineering and LLM automation while protecting sensitive healthcare data.

Design and build backend features and architecture for Coder’s enterprise platform. Improve scalability, database migrations, upgrade reliability, concurrency handling, and operational performance in regulated and air-gapped environments. Investigate production issues, document technical tradeoffs, participate in design reviews and code reviews, and support owned services through on-call rotations.

Leads the design, development, deployment, maintenance, and support of scalable web applications. Responsibilities include coding, debugging, code reviews, API-first development, performance optimization, testing, cloud-native deployments, database and caching strategy, production monitoring, incident response, mentoring engineers, and cross-functional collaboration with product, design, customers, and vendors.

Define technical direction for hyperscale Azure Storage components; architect, develop, test, and support highly scalable, secure, compliant, and highly available cloud services. Lead multiple engineering projects, improve reliability, scalability, performance, consistency, and observability, and apply AIOps for incident detection, root-cause analysis, and operational excellence.

Build and optimize Xbox growth experiments across services, clients, console, web, and mobile. Develop telemetry and analytics systems, analyze experimentation results, and drive retention and daily active users. Ship secure, reliable full-stack features, participate in on-call rotation, collaborate across teams, and use AI-enhanced workflows to accelerate engineering. Mentor engineers, shape product hypotheses, and own ideas from prototyping through rollout and scaling.

Design and scale platform infrastructure, backend services, developer tooling, CI/CD pipelines, and secure cloud-native systems. Improve developer experience, reliability, observability, and incident response while establishing security and compliance controls. Partner with engineering and product leaders to shape architecture and platform strategy, mentor engineers, and support customer-facing logistics projects. The role uses Python, AWS, Terraform, containers, orchestration, event-driven architectures, and relational databases.

Build and modernize backend services supporting patient scheduling, order management, and patient access workflows. Improve scalability, reliability, and maintainability across legacy healthcare applications, microservices, containerized infrastructure, and Kubernetes platforms. Collaborate with engineering, platform, product, and support teams while using CI/CD, automation, automated testing, and AI-assisted development practices to address complex technical challenges.

Lead design and implementation of Headway's insurance systems (eligibility, pricing, matching, claims). Build data-intensive, ML-powered platforms and automation, mentor engineers, write high-impact code, and improve accuracy and reliability across state and payer complexity to scale insurance-covered therapy.

Designs and develops scalable customer-facing web applications and microservices APIs. Leads complex system architecture, performs code reviews, mentors engineers, defines technical implementations, and guides engineering vision. Maintains sustainable business systems, supports compliance initiatives, and improves development processes. The role requires Java and Spring experience, cloud technologies, relational databases, REST and event-driven architectures, containerization, front-end development, and software lifecycle expertise.

Lead architecture and engineering for Azure core platform: define technology requirements, resolve cross-team issues, drive systemic reliability/performance improvements, mentor engineers, support on-call operations, and apply AI/ML to cloud operations.

Develop and evolve Azure capacity infrastructure, platform capabilities, and service stacks at scale. Provide technical leadership in requirements, architecture, design, coding, release planning, and operational reliability. Mentor engineers, manage cross-product dependencies, serve as a designated responsible individual, participate in on-call support, and improve system availability, observability, performance, and efficiency.

Lead quality engineering for a backend-heavy Immigration AI platform. Design test plans and cases, establish test environments, execute manual and automated testing, build custom frameworks and tooling, and test REST, asynchronous, event-driven, and backend services. Mentor engineers, conduct code reviews, identify automation opportunities, apply GenAI and LLMs, perform load and stress testing, and improve testing pipeline scalability, performance, and efficiency.

Leads the design, development, testing, debugging, and implementation of scalable software applications. Collaborates with product, design, and engineering stakeholders, conducts code reviews, mentors engineers, resolves performance issues, and improves development processes. The role requires proficiency in multiple programming languages, software testing, AI-assisted code generation, and preferably healthcare compliance, full-stack technologies, GraphQL, REST APIs, NoSQL, AWS, and infrastructure as code.

Leads Node.js sub-team architecture, technical standards, and complex full-stack development across frontend, mobile, and backend platforms. Builds React, TypeScript, Next.js, React Native, and Node.js features; designs APIs, authentication, caching, and data models; mentors engineers; and owns performance, testing, CI/CD, security, scalability, and HIPAA-compliant delivery.

Lead end-to-end feature development across frontend and backend for an enterprise data analytics platform. Design, implement, and maintain React UIs, backend services, APIs, databases, and distributed systems. Collaborate with Product, UX, and Engineering, mentor engineers, improve quality through testing/CI, and introduce new technologies including AI-assisted development.

Designs and develops software to automate onboarding, validation, management, tracking, and lifecycle operations for new hardware deployed in Microsoft datacenters. Responsibilities include requirements analysis, system design, coding, debugging, optimization, reliability engineering, monitoring, on-call support, and incident response. The role collaborates with Azure teams and stakeholders while improving scalability, security, availability, observability, and performance across cloud and distributed systems.

Design and implement PostgreSQL internals, indexing, query engine extensions, and storage-layer features to support large-scale document workloads on Azure. Profile distributed systems, tune performance, collaborate with open-source communities, conduct design/code reviews, and drive cross-team alignment for mission-critical database features.

Build and maintain on-chain smart contracts and backend services for branded USDC-backed stablecoins. Own issuance, reserves, mint/burn, and rewards systems; drive architecture, security, and operational excellence; ship features with product and design partners and ensure well-tested, auditable production deployments.

Own quality engineering for high-throughput payment systems by architecting automated regression, performance, stress, and load testing. Build emulators for external payment systems, integrate quality gates into CI/CD pipelines, validate microservices, event-driven architectures, and databases, and use Prometheus and Grafana for observability. Apply AI-assisted testing, synthetic data generation, and edge-case analysis while mentoring engineers and preventing incidents through telemetry-driven testing and post-mortems.

Principal Software Engineer responsible for expert-level coding, system architecture, technical strategy, code quality, SDLC improvement, and enterprise-scale modernization. Designs distributed systems and API integrations, governs architectural change, drives resiliency, security, observability, and performance standards, and influences stakeholders across multiple teams. Mentors engineers, leads technical initiatives without direct authority, manages technical risks and dependencies, and ensures compliance with regulatory, audit, and corporate engineering standards.

Hands-on Site Reliability Engineer responsible for production support, incident response, root cause analysis, observability, SLI/SLO development, synthetic monitoring, automation, and toil reduction. The role partners with software engineering to resolve application, database, API, and infrastructure issues, implement permanent fixes, improve reliability practices, and support a rotating on-call schedule.

Build and scale ML-optimized HPC infrastructure, manage Kubernetes-based GPU/TPU superclusters, optimize for AI/ML training, and mentor teams while innovating in ML infrastructure.

Build and maintain reliable, secure, scalable backend systems for Lithic’s product platform. Own projects end to end across API key management, reliability, audit logging, search, and API infrastructure. Improve system reliability, reduce technical debt, participate in on-call rotations, and lead team process improvements while collaborating asynchronously across time zones.

Build and operate highly scalable storage infrastructure supporting petabyte-scale imagery data. Responsibilities include developing backend services and APIs, managing object storage and metadata indexing, tuning Elasticsearch, improving disaster recovery, monitoring performance, responding to incidents, contributing to architecture and roadmaps, and advising engineers. The role requires strong production software engineering experience with Go or Python, cloud-native systems, relational and non-relational databases, and highly available services.