Top Senior IT Jobs in Charleston, SC

18 Days AgoSaved
Remote
Charleston, SC
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Develop, configure, and integrate BMC Helix/Remedy applications using Developer and Innovation Studio. Build workflows, forms, REST/WebService/LDAP integrations, data imports, and digital workplace offerings. Support onboarding, incidents, change requests, sprint work, demos, documentation, and production change management while following ITIL and Agile practices.
Top Skills: AWSBmc HdmBmc HelixBmc RemedyBmc Remedy ItsmCmdbDeveloper StudioDigital Workplace PortalHelix DashboardsInnovation StudioJIRALdapExcelMicrosoft PowerpointMicrosoft SharepointMicrosoft VisioMicrosoft WordPentaho SpoonRest ApiSaaSSmart ItSmart ReportingWeb Services
18 Days AgoSaved
Remote
Charleston, SC
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Develop and maintain BMC Helix/Remedy workflows, forms, and integrations (REST, WebService, LDAP). Gather requirements, produce design/test documentation, manage change requests and production, support customer onboarding and demos, participate in Agile sprints and on-call rotation, and pursue continual service improvements while minimizing customization and technical debt.
Top Skills: AWSBmc HdmBmc HelixBmc RemedyBmc Remedy ItsmDeveloper StudioDigital WorkplaceInnovation StudioJIRALdapLoggingExcelMicrosoft PowerpointMicrosoft SharepointMicrosoft VisioMicrosoft WordNetworking (Osi)Pentaho SpoonRelational DatabasesRest ApiSaaSWebservice
Reposted 18 Days AgoSaved
Remote
Charleston, SC
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design, develop, and maintain cloud-native applications using Node.js and React. Implement infrastructure-as-code (Terraform/CDK), deploy CI/CD pipelines, troubleshoot Linux systems, ensure secure AWS deployments, and collaborate with cross-functional teams to operate cloud workloads.
Top Skills: Api GatewayAWSAws CdkAws CodepipelineAws LambdaCloudwatchEc2Github ActionsGitlabIamJavaScriptJenkinsLinuxNode.jsReactRestful ApisS3TerraformTypescriptVpc
Reposted 18 Days AgoSaved
Remote
Charleston, SC
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Develop and maintain BMC Helix/Remedy workflows, forms, and integrations (REST API, WebServices, LDAP). Gather and document requirements, produce designs, test scripts, and demos. Support production changes, incident work, sprint delivery in Agile, participate in on-call rotation, and drive continual service improvements while minimizing customization and maintaining configuration control.
Top Skills: Asset ManagementAWSBmc HdmBmc HelixBmc RemedyBmc Remedy ItsmCmdbDeveloper StudioDigital Workplace Portal (Dwp)Helix DashboardsInnovation StudioJIRALdapExcelMicrosoft PowerpointMicrosoft SharepointMicrosoft VisioMicrosoft WordNetworking (Osi)Pentaho SpoonRelational DatabasesRest ApiSaaSSmart ItSmart ReportingWeb Services
Reposted 18 Days AgoSaved
Remote or Hybrid
Charleston, SC
Senior level
Senior level
Information Technology • Database • Consulting
Lead enterprise IT audit strategy and execution for insurance and financial systems. Oversee audits of core insurance platforms, financial systems, cybersecurity, cloud, IAM, SDLC, and regulatory compliance. Advise executives and regulators, manage remediation, prepare Audit Committee reporting, and mentor IT audit staff.
Top Skills: Audit AnalyticsAutomationCloudCobitContinuous MonitoringCosoErpGdprGeneral Ledger (Gl)IamIsoNistPci DssPolicy Administration SystemsSdlcSoc 1Soc 2Sox (Itgc)
Reposted 18 Days AgoSaved
Remote
Charleston, SC
173K-198K Annually
Senior level
173K-198K Annually
Senior level
Cloud • Information Technology • Other • Security • Software
Lead global sourcing strategy for IT and indirect categories, drive cost savings and supplier optimization, manage high-value negotiations and supplier risk, partner with cross-functional stakeholders, standardize processes, champion procurement transformation, and develop a global sourcing team.
Top Skills: CoupaErp PlatformsSap Ariba
Reposted 18 Days AgoSaved
Remote
Charleston, SC
109K-193K Annually
Senior level
109K-193K Annually
Senior level
Consumer Web • Fintech • Insurance
The Senior IT Engineer will design a cloud-based IT environment, enhance security practices, implement automation, lead projects, and mentor team members.
Top Skills: BashCloud PlatformsGoogle WorkspaceIntuneJAMFOktaProofpointPythonSlack
Reposted 18 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Cloud
Lead and deliver infrastructure and cloud migration projects (IaaS/PaaS), manage multiple project teams, stakeholder communications, budgets, risks, vendor coordination, and project governance from planning through execution.
Top Skills: AWSAzureCitrixIaasLinuxMicrosoftO365PaasPublic CloudSAPUnixVMware
Reposted 18 Days AgoSaved
Remote
Charleston, SC
147K-209K Annually
Senior level
147K-209K Annually
Senior level
Insurance
Senior IT leader responsible for leading a 30+ developer application development organization across multiple insurance lines. Owns modernization, legacy reduction, AI-enabled application delivery, cloud architecture, vendor evaluations, and roadmap alignment with business stakeholders while developing engineering managers and driving cross-line transformation.
Top Skills: Ai Coding AssistantsAi-Powered ApplicationsCi/Cd AutomationCloud PlatformsCloud-Native Development PlatformsGenerative AiGuidewireLarge Language ModelsLow-Code/No-CodeMendixMicrosoft Power PlatformOutsystemsP&C Insurance Platforms
19 Days AgoSaved
Remote
Charleston, SC
123K-167K Annually
Senior level
123K-167K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design, train and validate supervised ML models on multi-billion claim records to score fraud risk; engineer features in-warehouse; deploy and monitor models in production; provide human-readable rationale and claim-level evidence; collaborate with subject-matter experts and stakeholders to ensure actionable, explainable outputs.
Top Skills: AWSCptDrgEntity ResolutionGraph AnalyticsHcpcsIcd-10PythonSnowflakeSnowparkSQL
19 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Edtech
Lead commercial strategy and execution for IT spend categories (SaaS, cloud, endpoint, telecom). Manage renewals, run competitive sourcing events, negotiate pricing and contract terms, build TCO and spend analysis, coordinate legal and security reviews, maintain vendor frameworks, and align cross-functional stakeholders to deliver savings and reduce vendor risk.
Top Skills: AribaBi ToolsCoupaGoogle SheetsJIRAExcelSpend Analytics ToolsZip
Reposted 19 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Financial Services
Perform end-to-end FedRAMP assessments for cloud service providers: interview SMEs, review IaaS architectures (AWS/Azure/OCI), validate NIST SP 800-53 controls, analyze vulnerabilities, verify encryption and configurations, draft deliverables, and mentor project team members.
Top Skills: AWSAzureCi/CdDevsecopsFedrampExcelMicrosoft PowerpointMicrosoft WordNist Sp 800-53Oci
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Reposted 19 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Financial Services
Perform end-to-end FedRAMP assessments: interview CSP SMEs, walkthrough cloud architectures (AWS/Azure/OCI), evaluate NIST SP 800-53 controls, validate configurations and vulnerabilities, draft deliverables, train and mentor team members, and support practice development.
Top Skills: AWSAzureCi/CdCryptographyFedrampExcelMicrosoft PowerpointMicrosoft WordNist Sp 800-53OciSecdevops
20 Days AgoSaved
Remote
Charleston, SC
111K-150K Annually
Senior level
111K-150K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead and facilitate OPTN committee operations including meeting planning, governance documentation, policy development support, stakeholder coordination, training, and data analysis to ensure compliance with HRSA and federal regulations.
Top Skills: Committee Documentation SystemsExcelMicrosoft Office SuiteMicrosoft TeamsNvivoSharepointTableauVirtual Meeting Platforms
21 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Hospitality
Operate and improve IJM's Microsoft Azure environment: ensure availability, performance, security, monitoring, incident response, cost optimization, IaC deployments (Bicep/ARM/Terraform), automation with PowerShell/Azure CLI, governance (Azure Policy/RBAC), and collaborate across teams to maintain standardized, secure, and observable cloud platforms.
Top Skills: Application InsightsArmAzure CliAzure DevopsAzure IaasAzure MonitorAzure PaasAzure PolicyAzure Well-Architected FrameworkBicepGithub ActionsLog AnalyticsAzurePowershellRbacTerraform
21 Days AgoSaved
Remote
Charleston, SC
107K-160K Annually
Senior level
107K-160K Annually
Senior level
Healthtech • Social Impact
Facilitate IT demand intake, evaluate and prioritize requests, ensure decision-ready business cases, maintain demand/portfolio visibility, coordinate risk and compliance assessments, manage resource capacity and sequencing, and partner with PMO and stakeholders to optimize IT delivery and governance.
Top Skills: Database ManagementDimensionsElectronic Medical Record SystemsEpicItilExcelMicrosoft OutlookMicrosoft VisioMicrosoft WordServicenowWorkday
21 Days AgoSaved
Remote
Charleston, SC
162K-219K Annually
Senior level
162K-219K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Senior Business Systems Analyst combining strategic enterprise planning with hands-on functional analysis to drive cloud modernization and process transformation. Translate executive priorities into roadmaps, define complex functional requirements, perform capability modeling, support delivery and testing, and present recommendations to senior stakeholders.
Top Skills: JIRA
21 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Software • Consulting • Cybersecurity • Defense
Design, deploy, and manage scalable, secure cloud infrastructure. Implement networking, VMs, IaC, and configuration management. Integrate Azure infrastructure into CI/CD pipelines, automate provisioning with DevOps/GitHub Actions, and enforce security/compliance with security teams. Provide Windows Server administration and support enterprise cloud initiatives.
Top Skills: Active DirectoryAzureCi/Cd PipelinesConfiguration Management ToolsDhcpDnsFirewallsGithub ActionsGroup Policy Objects (Gpo)Infrastructure As CodeNetworking ProtocolsScriptingVirtual MachinesVpnWindows Server
21 Days AgoSaved
Remote
Charleston, SC
130K-160K Annually
Senior level
130K-160K Annually
Senior level
Information Technology • Robotics • Software • Consulting
Perform financial analyses for IT, develop Total Cost of Ownership and forecasting models, and recommend financial strategies. Support IT operations/governance, integrate financial checkpoints into governance, and apply Agile delivery principles to align services and outcomes.
21 Days AgoSaved
In-Office or Remote
Charleston, SC
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Biotech
Lead and continuously improve the global IT Compliance function for a CRO, ensuring IT governance, ISMS and ISO 27001 certification support, GxP computerised system compliance, audit readiness and vendor/third-party compliance oversight. Provide regulatory guidance, manage audit responses, run risk assessments, maintain compliance documentation, and drive remediation and continual improvement across IT and business stakeholders.
Top Skills: Ai And Machine LearningAudit Management ToolsCloud-Hosted SystemsDocument Management SystemsGrc PlatformsIsmsIso/Iec 27001Microsoft 365SaaSServicenowSharepointSmartsheet
22 Days AgoSaved
Remote
Charleston, SC
111K-150K Annually
Senior level
111K-150K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Serve as Product Owner for Oracle/Cerner clinical solutions, partnering with stakeholders to define workflows, write user stories, manage backlogs, configure systems, support enterprise deployment and adoption, and provide SME through the product lifecycle. Requires risk mitigation, cross-team collaboration, and occasional travel.
Top Skills: AgileBacklog ManagementCernerCharge ServicesCpaDentrixEhrOracleRevenue CycleScrumSurgery/Supply ChainUser Stories
22 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Healthtech • Information Technology
Serve as strategic advisor to assess and optimize end-to-end hospital revenue cycle operations using Epic workflows. Lead performance improvement, analytics, change management, compliance, and operational initiatives to improve financial and patient financial experience.
Top Skills: Epic CadenceEpic CertificationEpic HbEpic HimEpic PbLeanSix Sigma
Reposted 22 Days AgoSaved
Remote
Charleston, SC
140K-170K Annually
Senior level
140K-170K Annually
Senior level
Artificial Intelligence • Insurance • Software • Automation
Provide senior-level remote IT support and operations for a distributed workforce: troubleshoot macOS/Windows/Linux/mobile, manage onboarding/offboarding, administer identity (Rippling/Okta) and MDM, maintain asset inventory, build AI-driven automations (Console.com, Risotto, Unthread), support SOC 2/HIPAA/ISO compliance, write runbooks in Notion, and contribute to the IT roadmap while mentoring the team.
Top Skills: 1PasswordClaudeConsole.Com (Aria)Google WorkspaceLinuxmacOSMfaMobileNotionOauthOktaRipplingRisottoSAMLScimShell ScriptingSlackSnipe-ItSsoUnthreadWindowsZoom
Reposted 22 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Healthtech
The Senior IT Program Manager leads program development and implementation, ensuring projects align with business needs and are delivered on time and budget. They manage stakeholder relationships and facilitate communication with senior leadership, oversee financial management, and develop risk management strategies.
Top Skills: ConfluenceJIRAMicrosoft ProjectMS OfficeSnow Spm
Reposted 22 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Professional Services • Business Intelligence
Lead and execute IT audit and assurance engagements (SOX, SOC 1, SOC 2), perform ITGC/ITAC and automated controls testing, prepare workpapers and RCMs, provide technical guidance to clients, and mentor junior team members while contributing to practice development.
Top Skills: Automated ControlsAWSAzureErp SystemsGCPItacItgcRisk And Control Matrices (Rcm)Soc 1Soc 2Sox
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