Jobs at Keros Therapeutics

Keros invites individuals to join their Talent Community for future opportunities. They focus on diversity and building an inclusive culture.

The Senior Research Associate will develop and perform bioanalytical methods for preclinical and clinical programs, document results, and work collaboratively in a fast-paced environment.

Design and execute hypothesis-driven in vitro, ex vivo, and in vivo biomarker studies to support preclinical-to-clinical translation. Develop, qualify, and troubleshoot biomarker assays (ELISA/MSD, qPCR, Western blot, flow cytometry), analyze preclinical samples, evaluate reagents/platforms, support assay transfer to CROs, and present data and recommendations to cross-functional teams.

Lead analytical strategy and method development for protein therapeutics across preclinical to commercial stages. Oversee protein characterization, stability, CDMO/CRO oversight, analytical method validation, cross-functional collaboration, regulatory CMC support, and mentor a team of scientists.

Lead and manage the Process Development group for biologics, directing upstream and downstream process design, bench-to-pilot bioreactor scale-up, process characterization, tech transfer, cGMP production for tox material, cross-functional coordination, staff development, budgeting, and documentation to support IND/CMC activities.

Senior Process Engineer responsible for biologics upstream and downstream process development, scale-up, and technology transfer. Lead process design, pilot studies, CDMO transfers, data analysis, deviations/investigations, and author technical/CMC documentation. Provide hands-on cell culture support, ensure cGMP manufacturing readiness, and drive continuous process improvements and lifecycle management.

Lead PV science and operations for early-stage and clinical programs: oversee PV vendors and databases, drive signal detection and risk management, author aggregate safety reports and SOPs, ensure inspection and launch readiness, perform QC and document control, and collaborate cross-functionally to support regulatory submissions and pediatric risk strategies.

The Director of Regulatory Operations will manage all regulatory operations deliverables, oversee Health Authority submissions, and implement training for regulatory information management at Keros.