Top Remote Software Engineer Jobs in St. Louis, MO

Lead technical direction and architecture for mobile and enterprise solutions, remain hands‑on in critical systems, mentor senior engineers, drive CI/CD/DevSecOps, evaluate and integrate vendor and AI technologies, and establish engineering standards to improve quality, reliability, and delivery across programs.

Develop, test, deploy, and maintain .NET-centric web applications using C#, Angular 17+, and Azure. Build and consume REST APIs, work with SQL Server, source control, CI/CD pipelines, and collaborate on code reviews, debugging, performance optimization, and third-party integrations.

Seeking a Staff Software Engineer to design and build cloud-deployed systems. Must have extensive programming and leadership experience in software engineering.

The Senior Software Engineer, Protocol will architect and develop core protocol components for a blockchain while optimizing distributed systems. Responsibilities include enhancing performance, solving distributed systems problems, and contributing to engineering standards in collaboration with research and product teams.

Develop and maintain scalable software solutions, mentor developers, and integrate AI tools. Collaborate on technical solutions aligned with business goals.

Lead development of automated API, UI, and end-to-end tests for a real-time trading platform. Extend AI-assisted test generation, build scalable CI/CD test frameworks for order lifecycles and market-data streams, reduce flakiness, triage failures, mentor engineers, and drive quality and testability across the product.

The Senior Software Engineer will own the React Native mobile codebase, collaborate with cross-functional teams, and ensure high-quality delivery of customer-facing applications.

As a Senior Software Engineer, you will develop key product features for millions of users, collaborate with teams, and mentor others.

Develop and maintain PX4 autopilot firmware for UAVs, integrating sensors and payloads, and managing testing environments. Collaborate on flight operations and system integration.

As an Embedded Software Engineer, you will design and implement software for unmanned aircraft systems, debug issues, collaborate with engineering teams, and maintain high software quality standards.

Lead development of AI-powered full-stack applications, mentor engineers, define technical direction, build performant front-end and scalable backend services, integrate LLMs/RAG, and establish engineering best practices for production AI workflows.

Staff-level platform engineer to improve and scale inherited Scala systems, redesign data layers for ML/AI, build a Rust service framework, enhance observability and resilience, shape developer tooling and standards, and work across JVM, Rust, Python, SQL, and Spark.

Design, build, and operate large-scale distributed web-crawling and data ingestion systems. Improve throughput, reliability, observability, and data quality. Develop backend services for job orchestration and asynchronous workloads, partner with product teams to create data products, and mentor teammates on domain-specific acquisition techniques.

Lead backend-focused engineering to design and ship member- and care team-facing experiences. Own architecture end-to-end, set technical direction and quality standards, mentor engineers, and deliver scalable, secure APIs with CI/CD, cloud deployments, and GenAI/LLM-informed workflows.

Design and implement backend systems and APIs in Go, contribute full-stack features with React/TypeScript, define observability data models (OpenTelemetry), lead complex cross-team projects, own production services including on-call, mentor engineers, and collaborate with product and design to deliver AI observability features.

Build and iterate growth experiments, onboarding flows, promotions, and re-engagement campaigns. Design and integrate services/APIs and cloud infrastructure, instrument and analyze product data, apply AI where useful, improve system reliability, and mentor peers to drive activation, engagement, retention, and monetization.

Design, build, test, and deploy secure mission-planning software. Maintain secure CI/CD, containerized deployments, automated testing, and security-scanning workflows. Integrate AI capabilities, investigate vulnerabilities, support remediation, produce technical design documentation, and collaborate with stakeholders and customer leads.

Build and optimize high-volume web applications using .NET, Node, React and AWS; maintain and improve existing systems; troubleshoot bugs; perform code reviews; mentor junior engineers; participate in on-call rotation; and improve scalability and performance.

The Senior Software Development Engineer will develop applications using modern programming languages, provide leadership and mentoring, ensure software quality, and lead software improvement initiatives.

The Senior Software Engineer will build and ship full-stack features, design scalable systems, integrate AI tools, and maintain high coding standards in a fast-paced startup environment.

The role involves overseeing full-stack development, creating APIs, improving microservices, and collaborating with cross-functional teams to enhance mental health care interfaces.

The Principal Software Engineer will lead the design and build-out of an AI Context Layer, ensuring high-quality data for AI systems, while managing access control and developer interfaces, and leading cross-team projects.

The staff software engineer will lead technical design, develop AWS microservices and automation solutions, and mentor team members.

Lead design and implementation of health data products, mentor engineers, own multiple projects, and develop scalable data solutions using modern technologies.

The Senior Software Engineer will lead development, mentor engineers, and create data solutions using TypeScript, React, and Python. Responsibilities include designing applications, driving innovation, and ensuring high-quality user experiences.