Top Remote Software Engineer Jobs in San Diego, CA

Lead full‑stack development of the imaging web platform: architect and build ASP.NET Core services and Vue frontends, design secure APIs integrating EMRs and AI, own testing, CI/CD, and Azure deployments, mentor engineers, and collaborate with product, design, and clinical teams to deliver performant, reliable screening experiences.

Lead design and delivery of full-stack imaging features, architect high-performance ASP.NET Core services, build Vue frontends, integrate APIs with EMRs and imaging partners, mentor engineers, enforce automated testing, CI/CD and observability, and drive technical roadmap in an Agile team.

Join ASR as a Senior Software Engineer to maintain and develop swarming algorithms, enhance software architecture, and ensure operational reliability across our robotics systems. Responsibilities include extending the C++ code base and developing Python web services, requiring strong problem-solving skills in complex environments.

Founding platform engineering role to architect, build, and operate core platform systems (billing, integrations, Kubernetes/cloud infra, CI/CD, AI/LLM platform, observability). Own platform roadmap, mentor engineers, lead cross-team architecture, and diagnose/resolve production issues while establishing the Platform Engineering function.

Lead and contribute to Elasticsearch core search and indexing capabilities. Define technical vision for indexing, retrieval, and relevance; research data structures and retrieval algorithms; drive roadmap for large-scale search systems; collaborate with product and cross-functional teams; mentor engineers and implement robust, high-performance search infrastructure.

Design, build, and maintain scalable medical imaging software; evaluate and integrate AI-assisted development tools; collaborate with product and engineering teams; troubleshoot clinical environments; support CI/CD, testing, and deployment; participate in pair programming and knowledge sharing.

Lead design and development of software that interfaces with quantum processors, supporting calibration, hardware interfaces, testing, monitoring, and operational infrastructure. Drive architecture, optimize performance, mentor engineers, run technical investigations, and participate in on-call rotations to ensure QPU solver availability on the Leap cloud platform.

Own and deliver full-stack features across Ruby on Rails backend, React web, and Flutter mobile. Translate user needs into pragmatic solutions, drive architecture and production deployments, mentor teammates, address technical debt, and ensure reliability, performance, and security for mission-critical healthcare systems.

As a Senior Software Engineer, you'll lead efforts to improve configuration management and tackle challenges in identity and access management while promoting a culture of clean code and effective architectural solutions.

Lead end-to-end design, implementation, and operation of cloud partner integrations: auth/identity flows, multi-tenancy, data movement, CI/deployment, and observability. Own production systems and on-call duties, collaborate with partner platforms and internal teams, write design docs, and set technical defaults for a growing team.

Design, build, and maintain Python-based systems that interface with custom hardware. Own hardware drivers across serial/USB/I2C/SPI/Modbus, implement maintainable state machines, write async event-driven code, build RESTful APIs, persist device telemetry in SQL, contribute computer vision work, and collaborate with hardware, firmware, and operations while mentoring engineers and raising engineering standards.

The Senior Software Engineer, Payments will design and implement backend infrastructure for a blockchain-integrated banking platform, focusing on payment processing and operations.

Join Dakota's core engineering team to design and implement back-end infrastructure for a blockchain-integrated banking platform, addressing high-visibility projects.

As a Principal Software Engineer at Fetch, you'll design scalable systems for user engagement, drive experimentation, lead technical strategy, and mentor teams to improve engineering productivity and system reliability.

The Staff Software Engineer role involves leading projects, coordinating engineers, improving processes, and representing PayPal to external partners, focusing on cloud and DevOps responsibilities.

Design, build, and maintain automation and testing infrastructure for the North platform: CI/CD pipelines, GitHub workflows, containerized test environments (Docker/Kubernetes), Helm and ArgoCD deployments, infrastructure-as-code, benchmarking, parallel test execution, and cross-team standards to improve test coverage, reliability, and deployment confidence.

As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.

As a Senior Backend Engineer, you will enhance Postscript's Fondue product by architecting scalable systems, driving decoupling, and implementing AI-first development practices while collaborating across teams.

As a Staff Software Engineer, you'll design and develop systems to integrate AI in healthcare payment processes, mentor engineers, and optimize workflows.

The Senior Software Engineer will design and build scalable data solutions, manage backend systems, and enhance performance leveraging Golang and Python. Responsibilities include optimizing ETL processes and collaborating with teams to meet evolving customer needs.

The Staff Software Engineer will design and build scalable backend systems, lead projects, and contribute to enterprise software solutions, focusing on application architecture, API development, and ML techniques.

The Sr./Principal Software Engineer will design and implement core capabilities for SingleStore's cloud platform, focusing on scalability and reliability, while mentoring other engineers and collaborating with cross-functional teams.

Design, build, and operate shared backend services and APIs. Own full SDLC, define service boundaries and data models, ensure scalability and reuse, apply DDD and systems thinking, and use AI-assisted tools to accelerate development while maintaining maintainability.

Build and ship lightweight internal full-stack tools end-to-end within small pods. Rapidly prototype, deploy, operate, and iterate tools using cloud platforms and AI-assisted development to improve team productivity and automate workflows.

Design, build, and ship full‑stack applications end-to-end within small pods. Own the full SDLC, deploy and operate cloud applications, contribute to architecture, and use AI-assisted tools to accelerate development, testing, and code quality while maintaining reliability.