Top Remote Software Engineer Jobs in San Diego, CA

Own and modernize iHerb's product catalog across backend, React frontend, and relational data. Build end-to-end features, use AI-driven SDLC tools, write automated tests, ensure observability, participate in on-call incident response, and contribute to shared engineering standards.

The Staff/Principal Software Engineer will work in a remote global team, addressing software engineering challenges while fostering collaboration and clear communication.

Lead full‑stack development of the imaging web platform: architect and build ASP.NET Core services and Vue frontends, design secure APIs integrating EMRs and AI, own testing, CI/CD, and Azure deployments, mentor engineers, and collaborate with product, design, and clinical teams to deliver performant, reliable screening experiences.

Lead design and delivery of full-stack imaging features, architect high-performance ASP.NET Core services, build Vue frontends, integrate APIs with EMRs and imaging partners, mentor engineers, enforce automated testing, CI/CD and observability, and drive technical roadmap in an Agile team.

Design, build, and maintain Python-based systems that interface with custom hardware. Own hardware drivers across serial/USB/I2C/SPI/Modbus, implement maintainable state machines, write async event-driven code, build RESTful APIs, persist device telemetry in SQL, contribute computer vision work, and collaborate with hardware, firmware, and operations while mentoring engineers and raising engineering standards.

Develop and maintain backend services for the Leap quantum-classical cloud platform. Deliver features across the SDLC, improve system performance and scalability, troubleshoot and resolve production issues, participate in code reviews and on-call rotation, mentor junior developers, and collaborate with cross-functional teams to ship reliable, high-quality software.

Lead design and development of software that interfaces with quantum processors, supporting calibration, hardware interfaces, testing, monitoring, and operational infrastructure. Drive architecture, optimize performance, mentor engineers, run technical investigations, and participate in on-call rotations to ensure QPU solver availability on the Leap cloud platform.

As a Principal Software Engineer at Fetch, you'll design scalable systems for user engagement, drive experimentation, lead technical strategy, and mentor teams to improve engineering productivity and system reliability.

The Sr./Principal Software Engineer will design and implement core capabilities for SingleStore's cloud platform, focusing on scalability and reliability, while mentoring other engineers and collaborating with cross-functional teams.

Principal IC responsible for reliability, observability, and modernization of a .NET-based Platform Services portfolio on Azure. Own architecture, resilience patterns, shared libraries, and migration of legacy .NET services. Implement observability, event-driven messaging, and AI-first engineering practices while mentoring engineers and partnering with architecture teams.

Design, build, and operate cloud infrastructure and internal developer tooling to scale a production SaaS platform. Improve performance, scalability, and security, integrate observability, build AI-assisted automation, support production debugging and incidents, and participate in on-call rotations while enabling strong developer experience and documentation.

Lead design and hands-on development of AWS-based serverless backend and IoT cloud services. Build Python Lambda microservices, REST APIs, telemetry pipelines, and secure AWS IoT Core device communication. Mentor engineers, define architecture patterns, ensure production readiness (monitoring, CI/CD, security), and guide cross-functional integrations and technical roadmaps.

Own platform feature and API development, integrations, and deployments. Design, build, and maintain backend-focused full-stack features, collaborate with product and design, perform code reviews, troubleshoot, and work with cloud infrastructure and CI/CD pipelines to scale the marketplace.

Develop, deploy, and maintain the UDS Registry and related tools (Pepr, Lula). Lead architecture and implementation, integrate with defense systems, participate in on-call rotation, contribute to open source, produce documentation, mentor engineers, and influence product direction with user-focused design.

Design, build, and optimize scalable real-time and batch data pipeline infrastructure. Develop backend features focused on reliability and performance, write well-tested code, review technical designs, and contribute to infrastructure across mobile, desktop, and server systems.

Lead design and operation of the Synapse Everywhere external API platform: define API surface and guarantees, translate product and clinical requirements into contracts, own reliability and on-call incident response, provide technical mentorship and code reviews, and design scalable, secure cloud-native solutions (k8s, LLMs) with strong developer experience.

Design, build, and maintain scalable backend services in C#/.NET powering payment routing, connector management, and platform configuration. Build secure, observable APIs and high-volume transaction processing systems, collaborate across Product/AI/Engineering, mentor junior engineers, drive architecture and standards, and own full lifecycle from requirements to deployment.

Build, operate, and scale core data services and APIs to process, store, and deliver large-scale patient health records with low latency and high availability. Provide technical leadership, contribute to architecture and design, collaborate with product and engineering teams, and coach engineers.

The Senior Cloud Platform Engineer focuses on designing and supporting automation tools in AWS, ensuring security compliance, and advising development teams on best practices.

Lead delivery of high-complexity digital banking implementations: design and build Java Spring Boot microservices, REST APIs, cloud-native containerized deployments, data and DB migrations, event streaming, monitoring and performance optimization. Act as a customer-facing technical lead conducting code reviews, test strategies, and cross-functional coordination to resolve operational issues.

Join an early engineering hire at a growing SaaS platform for online communities. Scope and deliver new features, write modular TypeScript/React code, enable AI coding agents, monitor production, and troubleshoot issues while influencing product direction and improving platform scalability and developer experience.

Build and operate internal APIs and delivery systems for Data Science solutions. Implement deployment, security, auth, and observability; support integrations; runbooks and documentation; participate in on-call rotations, incident response, and post-incident improvements; provide code reviews and mentorship; design solutions on cloud, Kubernetes, and LLM-enabled infrastructure.

Lead design, development, testing, deployment, and support of cloud-based software products. Provide technical leadership and mentorship, translate feature requirements into implementation tasks, ensure quality (tests, performance, security), resolve technical risks and defects, and collaborate with stakeholders to deliver scalable microservices and AI-integrated features.

The Staff Software Engineer will lead AI integration into software design, develop scalable systems, and mentor other engineers while improving best practices.

Lead remote engineering teams to design, architect, and deliver scalable, high-availability education technology platforms focused on content systems, workflows, and GenAI. Drive product and technical strategy, collaborate with product/design, implement cloud-native architectures, adopt agile practices, measure performance through data and testing, and continuously improve user engagement and platform reliability.