Top Remote Python Jobs in San Diego, CA

Build and maintain data integration interfaces and ingestion pipelines between EHR systems and the Bayesian platform. Collaborate with client technical teams, implement automated integration tests, deploy and support go-lives, troubleshoot data correctness end-to-end, and develop tooling and automation (including LLM-driven) to scale integrations.

Lead full‑stack engineering projects across frontend and backend, design system architecture, collaborate with ML researchers and clinicians, implement user‑facing features, define APIs, write tests (unit/integration/e2e), produce technical specs, and use cloud infrastructure and CI to ship iteratively.

Own FPGA prototyping and silicon bring-up for next-generation communications ASICs. Build FPGA-based platforms, support first-silicon debug, validate high-speed interfaces, develop automated test infrastructure, and collaborate across ASIC, firmware, software, and systems teams.

Hands-on technical leader who manages and develops a networking engineering team; owns the enterprise networking roadmap; architects and delivers routing, switching, wireless, VPN, firewall, SD-WAN and cloud connectivity solutions; drives automation/IaC (Python, Ansible, Terraform, PowerShell), observability, resiliency, vendor management, and cross-functional collaboration; leads hiring, performance, and large-scale network modernization.

Lead full-stack product engineering for AI-powered healthcare features. Build frontend experiences, backend services, APIs, relational data models, and AI workflows. Prototype, ship, and iterate production systems; improve AI via evaluation and product signals. Ensure reliability, privacy, observability, and operational readiness while collaborating with product, design, customers, and engineers.

Design, build, and scale backend services and APIs (checkout, payments, scheduling, accounts) using Python, FastAPI, and PostgreSQL. Integrate third-party platforms, ensure resiliency and observability with Datadog, optimize performance, write automated tests, and mentor engineers while partnering with Product and Design to deliver customer-facing features.

Lead the vision, strategy, and architecture for observability and reliability platforms. Define SLOs/SLIs/SLAs, implement monitoring/alerting automation, lead incident response and post-incident analysis, evaluate tools, and mentor engineering teams to improve resilience, scalability, and reliability across multi-cloud environments.

Design, build, and ship full-stack features across mobile (Vue/TypeScript/Capacitor) and backend systems (Python/Flask/Postgres/Redis/AWS). Drive architecture, partner with Product and Design, decompose ambiguous problems into iterative work, participate in on-call rotation, and mentor through design and code reviews to support millions of users accessing government benefits.

Build full-stack integrations and observability tooling for Attentive's event-driven marketing platform. Design React/TypeScript frontends and backend services, optimize performance and scalability, improve code quality with testing and reviews, collaborate cross-functionally, and reduce technical debt while contributing to technical decisions.

The Principal Software Engineer will architect and oversee the development of distributed systems, mentor engineers, and drive architectural initiatives for large platforms.

Develop and maintain Alteryx Intelligent Services cloud and on‑prem products. Own design, implementation, testing, and contribute to DevOps pipelines and quality frameworks. Participate in code reviews, mentor teammates, collaborate with Product Management, and focus on delivering customer-centric, well-tested, performant software.

Own end-to-end full‑stack feature delivery for a CCM/GRC SaaS platform: design, implement, test, deploy, and maintain frontend (Angular), backend (.NET/C#/Python) services, and data layers (Postgres/SQL Server). Mentor juniors, participate in code reviews, collaborate across engineering functions, and ensure platform reliability and performance.

Design, build, and maintain scalable, secure GCP infrastructure using IaC (Terraform/Deployment Manager). Implement CI/CD, monitoring, backup/DR, and security/compliance controls. Integrate cloud data services, automate with Python/Bash and Ansible, troubleshoot issues, document architecture, and collaborate with cross-functional teams.

Design, build, test, and deploy production software for an agentic chatbot platform across intake, orchestration, retrieval, answer generation, caching, and integrations. Collaborate with product and technical teams, provide code and merge-request review, mentor junior engineers, and contribute to design, performance, security, and delivery.

Provide Linux system administration and Tier II support, manage AWS cloud infrastructure, automate provisioning and CI/CD, implement monitoring/alerting, configure DNS and web servers, use scripting (Python/Bash) and IaC tools (GitLab, Terraform, CDK), and support container orchestration (ECS/Kubernetes).

Reverse engineer, debug, develop, and test virtual iOS devices on a proprietary hypervisor. Port new iOS versions, build virtual peripherals/drivers, optimize performance and reliability, create automated test infrastructure, collaborate with hardware modeling, QA, and product teams, and produce internal technical documentation.

Lead design, implementation, and automation of Akamai's global network. Build and maintain IP/BGP routing, data center CLOS fabrics, and overlay technologies (VxLAN/EVPN). Create/manage configuration templates with Python, Ansible, and Jinja2. Troubleshoot complex multi-vendor environments and collaborate cross-functionally on data models and requirements.

Design, build, and deploy end-to-end analytic solutions for retail pricing and promotions. Architect scalable data pipelines in Palantir Foundry, collaborate with data scientists and stakeholders, implement AI/ML and LLM models, ensure governance and security, and drive product roadmap and process improvements.

Join Hone as a Quality Engineer II to own testing and automation for small features and bugs. Write and maintain test cases and reliable Playwright and API tests, chase flaky tests, run exploratory checks, produce clear bug reports, use AI-assisted tooling responsibly, and follow patient-data guardrails.

Design, build, and maintain MCP servers, internal APIs, lightweight Streamlit apps, and automated Python workflows. Ensure deterministic LLM integrations, enforce SOPs and coding standards, collaborate cross-functionally, and own projects end-to-end from architecture through deployment and maintenance.

Build and maintain MCP servers, internal APIs, lightweight Streamlit apps, stateful applications, and automated Python workflows to expose and orchestrate data platform and enterprise systems for internal tools and AI workflows.

Build, ship, and maintain full-stack features for North: large-scale file uploads, shared knowledge bases, agent extensibility, and data-sync pipelines. Own end-to-end design, implementation, testing, launch, and iteration while working closely with Product, UX, and modeling teams. Prioritize security, performance, and mentoring.

Lead technical direction with the CTO, architect and build high-scale distributed systems, mentor engineers, ship product roadmap, manage cloud infrastructure and orchestration, enforce CI/CD, testing and fault-tolerance, and collaborate with product and business teams while leveraging AI/ML frameworks.

Senior software engineer responsible for architecting and implementing high-scale distributed systems, leading small engineering teams, mentoring junior engineers, and delivering reliable cloud-deployed services using Python, container orchestration, and CI/CD best practices.

The Staff Software Engineer will architect and implement core services and systems, provide technical leadership, and mentor engineers while focusing on scalable, high-performance software development.