Top Remote Python Jobs in Raleigh, NC

Reposted 16 Hours AgoSaved
Easy Apply
Remote or Hybrid
Remote Raleigh, NC
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
39 Minutes AgoSaved
Remote
Remote Raleigh, NC
Junior
Junior
Artificial Intelligence • Blockchain • Digital Media • Information Technology
Develop and maintain Python applications focusing on iterators/generators/streams, concurrency (multithreading, non-blocking I/O), and high-precision numeric handling. Work with JSON/XML, REST and SOAP APIs, ACID-compliant databases, message brokers/queues, and produce clean, SOLID code. Unit and integration testing experience is beneficial.
Top Skills: Acid-Compliant DatabasesDecimal ModuleFractions ModuleGeneratorsIntegration TestingIteratorsJSONMessage BrokersMessage QueuesMulti-ThreadingNon-Blocking I/OParallelismPythonRegular ExpressionsRestSoapStreamsUnit TestingXML
YesterdaySaved
Remote or Hybrid
Remote Raleigh, NC
Internship
Internship
Artificial Intelligence • Software • Consulting • Automation
Work as a Python development intern building applications and APIs, processing and analyzing data, working with databases and data pipelines, contributing to system architecture, writing clean documented code, and collaborating with the team. Strong emphasis on backend development, SQL, ORMs, and REST API design with potential conversion to full-time.
Top Skills: DjangoDjango OrmFastapiFlaskGitGitHTTPJSONMySQLNumpyPandasPostgresPythonRest ApiSQLSqlalchemySqlite
Reposted 3 Days AgoSaved
Remote
Remote Raleigh, NC
Mid level
Mid level
Information Technology
Concept Plus seeks a Junior Python Developer to enhance enterprise-scale applications, focusing on backend development, DevSecOps practices, and secure coding under senior guidance.
Top Skills: Ci/CdGitPyodidePythonRest ApisWebassembly
5 Days AgoSaved
Remote
Remote Raleigh, NC
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Reposted 9 Days AgoSaved
Remote
Remote Raleigh, NC
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 11 Days AgoSaved
Remote
Remote Raleigh, NC
Senior level
Senior level
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills: DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Reposted 11 Days AgoSaved
In-Office or Remote
Remote Raleigh, NC
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
9 Days AgoSaved
In-Office or Remote
Remote Raleigh, NC
160K-190K Annually
Senior level
160K-190K Annually
Senior level
eCommerce • Fintech • Payments • Software
Design and build end-to-end AI-driven automation to replace manual operational workflows. Partner with ops, sales, and support to discover problems, architect agentic orchestration, deploy production systems, measure impact, and iterate with robust guardrails and error handling.
Top Skills: Ai AgentsApexAutogenAWSAzureCi/CdClaude CodeCrewaiCursorGCPGitGithub ActionsGithub CopilotJavaScriptJIRALanggraphLightningLlmsPythonSalesforceSalesforce ApisSlackTypescriptWindsurf
23 Minutes AgoSaved
Remote
Remote Raleigh, NC
Senior level
Senior level
Information Technology • Professional Services • Software • App development
Develop and maintain backend services for SmartPal conversational AI: design and implement Python services on Kubernetes/AWS, connect to MongoDB/PostgreSQL, build RESTful APIs, implement test automation, and collaborate across discovery, prototyping, and production monitoring.
Top Skills: AWSDockerGrafanaJavaKibanaKubernetesMachine LearningMongoDBNatural Language ProcessingNode.jsPostgresPrometheusPythonRestful Apis
Reposted 9 Days AgoSaved
In-Office or Remote
Remote Raleigh, NC
150K-300K Annually
Senior level
150K-300K Annually
Senior level
Big Data • Cloud • Healthtech • Software • Big Data Analytics
The Principal Software Engineer will lead AI-driven product development, overseeing the entire feature lifecycle, mentoring engineers, and collaborating on design solutions.
Top Skills: FastapiGitPydanticPython
8 Hours AgoSaved
Remote
Remote Raleigh, NC
Senior level
Senior level
Information Technology • Logistics • Transportation • Consulting
Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.
Top Skills: .NetC#Ci/CdDevOpsDockerElectronFastapiGraphQLJavaJavaScriptLlmsLookmlMlMongoDBMySQLNode.jsPythonReact NativeReactRestSpringTypescriptVue
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YesterdaySaved
Remote
Remote Raleigh, NC
120K-145K Annually
Senior level
120K-145K Annually
Senior level
Software
Design, build, and maintain enterprise-quality Python serverless applications on AWS; integrate services and external APIs, implement state machines and CI/CD, write automated integration tests, troubleshoot and support production systems, and advise stakeholders on solutions.
Top Skills: AutomationAWSCi/CdCloudFormationEcs FargateEsbIntegration TestingPostgresPythonRest ApisServerlessSQLState MachinesWorkflow Engine
YesterdaySaved
Remote or Hybrid
Remote Raleigh, NC
Senior level
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Build and maintain full-stack product features alongside cross-functional teams, contribute across architecture tiers, write tested maintainable code, collaborate with product managers, participate in re-architecture and technical design, and use logging and performance techniques to ensure low-latency, reliable user experiences.
Top Skills: AWSBigQueryDynamoDBGraphQLHTTPKafkaMySQLNeo4JNext.JsNode.jsOauthPostgresPythonRdsReactRestSnowflakeTypescriptVercel
YesterdaySaved
Remote
Remote Raleigh, NC
Mid level
Mid level
Artificial Intelligence • Computer Vision • Machine Learning • Software
Build and maintain Django-based web applications, design RESTful APIs, implement frontend features (HTML/CSS/JS), optimize performance and security, collaborate with cross-functional teams throughout the development lifecycle.
Top Skills: CSSDjangoGitHTMLJavaScriptMySQLPostgresPythonRestful Apis
Reposted 2 Days AgoSaved
Remote
Remote Raleigh, NC
Senior level
Senior level
Automotive
The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.
Top Skills: AirflowAWSElasticsearchKubernetesOcrOpensearchPythonScrapySpark
Reposted 3 Days AgoSaved
Remote
Remote Raleigh, NC
Senior level
Senior level
Information Technology
The Senior Python Developer will design and implement secure backend systems using Python and Pyodide, ensuring compliance with DoD cybersecurity requirements and cloud deployment practices. Responsibilities include leading Python code optimization, supporting CI/CD pipelines, and participating in Agile sprint cycles, all while collaborating with cross-functional teams and ensuring secure coding standards.
Top Skills: 800-171APIsCi/CdCloud OneCmmcDevsecopsDisa StigsNist Sp 800-53PyodidePythonWebassemblyZero Trust
Reposted 4 Days AgoSaved
Remote
Remote Raleigh, NC
Senior level
Senior level
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills: AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
Reposted 5 Days AgoSaved
Remote
Remote Raleigh, NC
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
6 Days AgoSaved
Remote
Remote Raleigh, NC
Mid level
Mid level
Agency • Artificial Intelligence • Blockchain • Web3
Build and maintain API services for a decentralized exchange, design and implement trade routing logic for optimized cross-chain swaps, integrate features with cross-functional teams, monitor system performance and reliability, and troubleshoot trade execution and API issues.
Top Skills: Node.jsPythonRedisSQL
Reposted 6 Days AgoSaved
Remote
Remote Raleigh, NC
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
8 Days AgoSaved
Remote
Remote Raleigh, NC
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
9 Days AgoSaved
Remote
Remote Raleigh, NC
130K-165K Annually
Senior level
130K-165K Annually
Senior level
HR Tech • Legal Tech • Software • Consulting
Design, implement, and maintain SaaS features using Python and React on AWS. Lead system design, code reviews, CI/CD pipelines, AI-integrated development (LLMs and AI coding agents), prompt engineering, testing (Cypress), and on-call production support. Mentor teammates and ensure secure, scalable, well-documented software.
Top Skills: AWSCicdClaude CodeCodexContainerized EnvironmentsCypressDevin.AiLlmMcpMySQLPython 3.11ReactRestful Apis
Reposted 9 Days AgoSaved
In-Office or Remote
Remote Raleigh, NC
Mid level
Mid level
Cloud • Software
We are seeking a software engineer to build and validate resilient distributed systems, enhance CI pipelines, and improve testing strategies for cloud applications.
Top Skills: AWSCircleCIGithub CiGoJenkinsKubernetesOpenstackPythonTerraform
Reposted 9 Days AgoSaved
In-Office or Remote
Remote Raleigh, NC
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
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