Top Remote Python Jobs in Houston, TX

Embed with customers to discover needs, design and implement production-grade integrations (APIs, data pipelines, event-driven workflows), deploy and troubleshoot solutions, train IT teams, and drive adoption and measurable business outcomes.

Configure and implement Alkami digital banking products and third-party integrations, troubleshoot technical issues, perform testing and validation, document configurations, coordinate with project managers and vendors, and support clients through implementation and post-go-live stabilization.

Lead technical design and delivery of scalable, cloud-native SaaS solutions. Drive architecture and implementation across frontend and backend stacks, mentor engineers, apply AI/agent workflows and NLP, ensure high availability, and collaborate with product and cross-functional teams to ship reliable, production-grade systems.

Lead backend architecture and implementation for a healthcare scheduling platform rebuild: build FastAPI service controllers and Pydantic schemas, port legacy Python services to FastAPI/SQLAlchemy, own PressW-side cloud infrastructure (EKS, networking, IAM, observability), coordinate migrations and translation layers, drive code quality and testing, and mentor mid-level engineers.

Lead frontend and mobile rebuild of a healthcare scheduling platform using Vite + React 19 and Expo/React Native with a shared TypeScript layer. Own identity and access migration to a modern IAM, implement push notifications, build a component library/design system, instrument analytics and session replay, enforce WCAG 2.1 AA accessibility and performance standards, mentor mid-level engineers, and contribute to hiring.

Design and develop core backend systems and APIs for AI applications, ensuring performance and reliability while collaborating with frontend teams.

Designs and develops silicon photonics integrated circuits, managing the entire development process, including testing and analysis for cutting-edge photonic devices and systems-on-chip.

As a Senior Fullstack Engineer, you'll architect and build a high-concurrency auction engine, leveraging AI for enhanced user experiences and system reliability.

As a Senior Fullstack Engineer, you'll build financial systems, design lending infrastructure, implement payment integrations, and create user interfaces, ensuring correctness and reliability.

Design, build, and operate scalable backend services and APIs for a SaaS platform using Python/FastAPI. Ensure reliability, performance, and observability across distributed systems. Work with PostgreSQL, SQLAlchemy, Temporal, Redis, AWS, and Terraform. Build frontend features with React and TypeScript, integrate third-party APIs, adopt AI-assisted development tools, mentor engineers, and drive architecture and developer experience improvements.

As a Database Reliability Engineer at ClickHouse, you'll improve reliability, manage escalation processes, support incident response, and enhance database performance while collaborating across teams.

Design and build operational data systems, including pipelines, storage layers, and APIs for near real-time enforcement and insights, balancing streaming and batch paradigms.

The role involves building and debugging components across the stack, focusing on patient care coordination tools, while collaborating with AI technology.

Design, implement, and operate hybrid-cloud infrastructure and platform services. Automate infrastructure (IaC), manage Kubernetes (EKS and on-prem), provision distributed systems (Spark, Kafka, databases), build CI/CD pipelines, improve cloud governance/security, and collaborate with trading, development, and operations teams to maintain reliable production systems.

The ML Platform Engineer will build scalable architecture for ML training workloads, optimize system performance, and collaborate with teams for enhanced efficiency on Kubernetes.

The Lead Cloud Solution Architect will design, implement, and manage Hybrid Cloud solutions while providing technical leadership and consulting for clients. Responsibilities include engaging with business leaders, managing projects, and ensuring high-quality service delivery.

The Senior Backend Engineer will develop core functionalities for AI-driven drug discovery, collaborating with R&D and product teams, managing infrastructure, and ensuring engineering excellence.

Lead software engineering efforts for the Proton platform, focusing on system design, mentorship, and innovative drug discovery projects. Collaborate with cross-disciplinary teams to enhance engineering processes and standards within a minimalist organizational structure.

The Senior Forward Deployed Engineer will deploy and validate AQNav systems, drive success during tests, communicate with stakeholders, and bridge operations with research and engineering.

The Senior Backend Engineer will lead client projects, build AI solutions, and develop technical standards while mentoring junior engineers.

Lead design and delivery of customer-facing data product applications, building full-stack experiences (frontend, backend, APIs) using TypeScript, React, Node.js, and Python. Partner with Product and data teams to convert analytics and prototypes into production-grade workflows, establish software engineering best practices, mentor engineers, and prioritize customer value through testing, observability, and operational ownership.

The Senior Full Stack Engineer builds and ships features across frontend and backend systems, working with various frameworks and databases, while collaborating on technical specifications and improving developer experiences.

The Senior Software Engineer will develop orchestration and autoscaling for the Lucenia search platform, working with cloud technologies and Kubernetes to manage services and mentor team members.

Join k-ID's Engineering Internship Program to work on privacy-centric tools for kids online, building features and fixing bugs in a collaborative environment.

Join Arista Networks as a Site Reliability Engineer to manage CloudVision service reliability, scalability, and stability in a FedRAMP environment, focusing on areas like architecture, security, and performance optimization.