Top Remote Python Jobs in Houston, TX

Reposted YesterdaySaved
Remote
Remote Houston, TX
170K-205K Annually
Senior level
170K-205K Annually
Senior level
Artificial Intelligence • Marketing Tech • Mobile • Software
Own and improve Attentive's first-party data collection across the JS tag, Cloudflare Workers, and Java backend. Expand edge compute capabilities, build agentic AI systems to detect and fix data-quality issues, harden the event ingestion pipeline for reliability and observability, and lead technical direction on a small autonomous team while mentoring engineers.
Top Skills: AirflowAuroraAWSClaude CodeCloudflareCloudflare WorkersCodexCursorDatadogDynamoDBEksEsbuildFastlyGradleGraphQLHelmHuggingfaceIstioJavaJavaScriptKotlinKubernetesLambda@EdgeMetaflowPandasPlaywrightPostgresPythonPyTorchRadix UiReactRedisSpring BootStorybookTensorFlowTerraformTypescriptVite
YesterdaySaved
Remote
Remote Houston, TX
Senior level
Senior level
Healthtech
Build, secure, and operate AWS infrastructure and container platforms while administering Linux, Windows Server, Nutanix, Rancher, and ECS Anywhere environments. Manage infrastructure as code, CI/CD, automation, SMTP relays, SSL/TLS certificates, monitoring, reliability, and compliance. The role requires hands-on troubleshooting, independent work, on-call participation, and flexibility across cloud engineering, systems administration, and operational support.
Top Skills: Active DirectoryAhvAmazon Ecs AnywhereAmazon SesAWSAws Certificate ManagerAws CloudformationAws Systems ManagerBashBoto3CattleCloudwatchDhcpDkimDmarcDnsEc2EcsGroup PolicyIamIisLinuxLoad BalancingNutanixOpensslPemPfxPostfixPowershellPrism CentralPrism ElementPythonRancherRdsRoute 53S3Security GroupsSmtpSpfSsl/TlsTcp/IpVpcVpnWindows Server
YesterdaySaved
Remote
Remote Houston, TX
140K-200K Annually
Senior level
140K-200K Annually
Senior level
Manufacturing
Builds production-grade AI tools, molecule discovery applications, process digital twins, and full-stack internal software. Partners with laboratory scientists and infrastructure engineers to integrate scientific data, automate workflows, and support chemical production scale-up. Responsibilities include backend services, APIs, data access layers, user interfaces, secure deployment, testing, documentation, and auditability in a regulated environment.
Top Skills: Agentic WorkflowsAi ApisAPIsDigital TwinsLimsLlmsPythonRetrieval-Augmented GenerationTypescript
YesterdaySaved
Remote
Remote Houston, TX
160K-280K Annually
Senior level
160K-280K Annually
Senior level
Artificial Intelligence • Other • Sales • Software
Own Cresta’s web platform, CMS architecture, component system, analytics and GTM integrations, localization, SEO/AEO implementation, and engineering practices. Build tooling that enables marketers to work independently and develop, deploy, evaluate, and optimize AI agents for marketing use cases. Partner with brand, design, marketing operations, product, and engineering teams while providing technical leadership and owning projects end to end.
Top Skills: Ai Agent FrameworksCmsFunction CallingGoogle Analytics 4Google Tag ManagerHubspotLlmsMarketoNode.jsPrompt EngineeringPythonRetrieval-Augmented Generation (Rag)SalesforceSegmentTypescriptWebflow
YesterdaySaved
Remote
Remote Houston, TX
Junior
Junior
Software • Manufacturing
Early-career Software Engineer developing and maintaining Windows desktop fluid-flow simulation applications. Responsibilities span user interfaces, application logic, data models, integrations, testing, debugging, build automation, CI/CD, and modernization. The role involves collaboration with engineering, QA, product, and domain experts while contributing clean, maintainable code and participating in reviews, bug triage, and build pipeline rotations.
Top Skills: .NetBitbucketC#C++Ci/CdGitJavaJIRAJSONPowershellPythonVb.NetVisual StudioWindowsWinformsWpfXML
Reposted YesterdaySaved
Remote
Remote Houston, TX
Senior level
Senior level
Information Technology • Security • Cybersecurity
Own production operations and highly available cloud infrastructure for regulated government environments. Lead incident response, root-cause analysis, disaster recovery testing, compliance operationalization, audit readiness, vulnerability management, and continuous monitoring. Build automation, secure CI/CD pipelines, infrastructure-as-code, observability, and compliance tooling across Kubernetes, Linux, containers, and cloud platforms. Partner with security, compliance, and engineering teams to improve reliability, deployment safety, and regulatory sustainment.
Top Skills: Aws GovcloudBashCi/CdDod Il4Dod Il5FedrampGitopsGoGrafanaKubernetesLinuxNist 800-53PrometheusPythonStigTerraformUnixZero Trust
YesterdaySaved
Remote
Remote Houston, TX
180K-200K Annually
Expert/Leader
180K-200K Annually
Expert/Leader
Cloud • Information Technology
Principal Engineer responsible for owning complex software initiatives from problem framing through architecture, implementation, deployment, production support, and continuous improvement. The role involves building web applications, services, APIs, MCP servers, data pipelines, and platform integrations; leading architecture and code reviews; improving security, reliability, and maintainability; mentoring engineers; and shaping technical strategy. The engineer will also use and improve AI-assisted development practices while maintaining human accountability for quality and operational outcomes.
Top Skills: Ai Coding AgentsAPIsC#ContainerizationContinuous IntegrationDbtDeployment AutomationElixirGoJavaJavaScriptKotlinModel Context Protocol (Mcp)Next.JsObservabilityPostgresPythonRubySnowflakeTypescript
YesterdaySaved
In-Office or Remote
Remote Houston, TX
93K-121K Annually
Senior level
93K-121K Annually
Senior level
Information Technology
Develop and maintain modern full-stack applications using React, TypeScript, Python, and API frameworks. Responsibilities include technical planning, architecture, testing, deployment, documentation, performance, security, CI/CD, and production support. The role integrates generative AI, LLMs, RAG, intelligent search, AI agents, and workflow automation into enterprise applications. It also involves collaborating with product, UX, architecture, data, and engineering teams; conducting code reviews; mentoring junior engineers; and evaluating emerging technologies.
Top Skills: AgileAi AgentsAi OrchestrationAutomated TestingAWSAzureCi/CdCSS3DevOpsDockerFastapiFlaskGenerative AiGitGoogle Cloud Platform (Gcp)GraphQLHTML5JavaScriptKubernetesLarge Language Models (Llms)MicroservicesPrompt EngineeringPythonReactRest ApisRetrieval-Augmented Generation (Rag)Typescript
Reposted YesterdaySaved
Remote
Remote Houston, TX
120K-135K Annually
Senior level
120K-135K Annually
Senior level
Other
Lead design and hands-on development of AWS-based serverless backend and IoT cloud services. Build Python Lambda microservices, REST APIs, telemetry pipelines, and secure AWS IoT Core device communication. Mentor engineers, define architecture patterns, ensure production readiness (monitoring, CI/CD, security), and guide cross-functional integrations and technical roadmaps.
Top Skills: Api GatewayAuroraAws Iot CoreAws LambdaCi/CdCloudwatchDevice ShadowsDynamoDBEventbridgeIamJwtMqttOauth/OidcPythonRdsRest ApisS3Secrets ManagerSqsTerraform
YesterdaySaved
Remote
Remote Houston, TX
190K-300K Annually
Senior level
190K-300K Annually
Senior level
Professional Services • Consulting
Own backend and product delivery from scoping through production. Design customer-facing backend services, AI agent capabilities, APIs, data models, and system architecture for large unstructured datasets. Lead high-impact technical initiatives independently, maintain engineering quality, shape product direction with founders, and translate customer needs into dependable software. The role requires advanced Python, production-scale backend experience, system design expertise, and a product-minded approach.
Top Skills: Agent-Based AiAi Coding AssistantsAPIsLarge Language ModelsPythonRelational Databases
Reposted YesterdaySaved
Remote
Remote Houston, TX
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Define architectural direction for Azure Specialized platform services and lead the design of highly available distributed cloud systems. Drive reliability, scalability, observability, security, diagnostics, and operational improvements across engineering organizations. Establish service health frameworks, SLOs, metrics, and governance for mission-critical services. Mentor engineers, influence technical strategy, resolve complex cross-system challenges, and advance AI-assisted troubleshooting and platform modernization.
Top Skills: Artificial IntelligenceAzureCC#C++Cloud InfrastructureDistributed SystemsJavaJavaScriptNetworkingObservabilityPythonTelemetry
YesterdaySaved
Remote
Remote Houston, TX
155K-225K Annually
Entry level
155K-225K Annually
Entry level
Cybersecurity
Build scalable web applications, APIs, data pipelines, and data integrations for a cybersecurity platform. Responsibilities include architecting software for high-volume data environments, designing algorithms and data structures, optimizing storage and performance, maintaining coding standards, supporting analytics data systems, and collaborating across technical and non-technical teams throughout the product lifecycle.
Top Skills: Apache IcebergAWSCi/CdETLGCPAzureMySQLPhlexPostgresPythonRubyRuby On RailsRubyllmS3 TablesTurbo Streams
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YesterdaySaved
Remote
Remote Houston, TX
176K-282K Annually
Expert/Leader
176K-282K Annually
Expert/Leader
Aerospace • Information Technology • Security • Cybersecurity • Defense
Leads systems architecture and solution development for complex federal programs, translating requirements into executable cloud-native solutions. Advises executives and government customers while guiding integrated product teams developing AI/ML capabilities on AWS. Responsibilities include software architecture, distributed systems, REST APIs, microservices, automation, testing, security compliance, and technical documentation. The role requires extensive software engineering experience, active Secret clearance, Agile expertise, and familiarity with Navy weapon systems and NAVAIR.
Top Skills: Agentic AiAi/MlAutomated TestingAWSBashCi/CdFastapiFedrampGoHttp/Https ApisInfrastructure As CodeJavaJSONKubernetesLarge Language Models (Llm)MicroservicesAzureMosaOpenapiPythonReactRestRetrieval-Augmented Generation (Rag)RmfSafeScrumSwaggerTailwindTypescriptUnix/LinuxZero Trust
Reposted YesterdaySaved
Remote
Remote Houston, TX
Internship
Internship
Artificial Intelligence • Cloud • Information Technology • Consulting
Perform load, stress, and endurance testing across e-commerce storefronts, internal SaaS tools, and AI agent services. Design test strategies, execute tests with tools like JMeter/Gatling, analyze observability metrics, identify bottlenecks in Node.js/NestJS, PostgreSQL, and Redis, and integrate performance tests into CI/CD while collaborating with SRE and backend teams.
Top Skills: Cloud Load Testing ServicesDockerGatlingGrafanaJavaScriptJmeterJSONLlmMeilisearchNestjsNode.jsOpentelemetryPostgresPrometheusPythonRagRedisRest
Reposted YesterdaySaved
Remote
Remote Houston, TX
Internship
Internship
Artificial Intelligence • Cloud • Information Technology • Consulting
Internship SRE role responsible for availability, performance, and scalability of an e-commerce supply-chain platform. Tasks include SLO/SLA definition, observability (Prometheus/Grafana/Loki/Tempo/OpenTelemetry), incident response, capacity planning, disaster recovery for PostgreSQL, infrastructure-as-code (Terraform), CI/CD automation, and operational reliability for AI agent services. Mentored by Head of Technology/CTO with potential conversion to full-time based on performance.
Top Skills: BashCi/CdDockerGrafanaLangchainLlmLokiMakefileNestjsOpentelemetryOracle CloudPgbackrestPostgresql 15PrometheusPythonRedisTempoTerraformTraefik
Reposted YesterdaySaved
Remote or Hybrid
Remote Houston, TX
150K-180K Annually
Senior level
150K-180K Annually
Senior level
Artificial Intelligence • Legal Tech • Software
Design, build, and scale Shepherd’s core platform, backend systems, APIs, user-facing applications, and AI-powered legal workflows. Architect secure, reliable infrastructure for sensitive legal data, collaborate with legal and product teams, build internal tools, optimize performance, and own technical decisions. The role also involves rapid prototyping, mentoring and recruiting engineers, and contributing to SOC 2 readiness and data privacy practices.
Top Skills: AnthropicAWSDevOpsEmbeddingsGCPLlmsNode.jsOpenaiPythonRagReactSoc 2TypescriptVector Databases
Reposted YesterdaySaved
Remote
Remote Houston, TX
Senior level
Senior level
Information Technology • Consulting
Designs, develops, and deploys enterprise applications using Java, Spring Boot, microservices, REST APIs, cloud services, databases, DevOps tools, and Angular or React. The role also involves AI exposure with Python, LangChain, and LangGraph, along with application security, monitoring, performance, deployment, and collaboration with project teams. The position is onsite in McLean, Virginia.
Top Skills: Amazon Ec2Amazon S3AngularApigeeArtifactoryAWSAws IamAws LambdaBitbucketDockerElasticsearchGitGradleHibernateIstioJ2EeJava 8+JenkinsJpaKibanaKubernetesLangchainLanggraphLogstashMavenMicroservicesMongoDBOauthPing IdentityPostgresPythonRdbmsReactRest ApisSpringSpring BootUnix
Reposted YesterdaySaved
In-Office or Remote
Remote Houston, TX
148K-265K Annually
Senior level
148K-265K Annually
Senior level
Big Data • Cloud • Digital Media • Machine Learning • Mobile • Software • Industrial
Lead and mentor a high-performing Platform/DevOps team, manage application delivery, and improve internal CICD platforms while ensuring reliability and observability of systems.
Top Skills: Argo CdAWSCi/CdCloudwatchDynatraceEksGrafanaJavaJenkinsKubernetesNode.jsPrometheusPythonSplunkTerraformTypescript
Reposted YesterdaySaved
Remote
Remote Houston, TX
Junior
Junior
Artificial Intelligence • Insurance • Software • Automation
Build and maintain backend services and APIs, write unit tests, debug and optimize systems, support migration from Supabase to cloud, improve reliability, and integrate AI/RPA workflows while learning under senior mentorship.
Top Skills: AIAWSAzureGCPJavaScriptNode.jsPostgresPythonReactRobotic Process Automation (Rpa)Supabase
Reposted 2 Days AgoSaved
In-Office or Remote
Remote Houston, TX
Mid level
Mid level
Healthtech
Own end-to-end product features for a SaaS platform serving HR, therapists, and employees. Build, scale, and evolve frontend and backend components, lead architecture and standards, collaborate with design and product, and incorporate customer feedback and QA. Work in an early-stage startup environment with product-focused ownership.
Top Skills: Next.JsPythonReact
Reposted 2 Days AgoSaved
Remote
Remote Houston, TX
Mid level
Mid level
Information Technology • Software • Consulting • App development
Design, build, and maintain cross-platform mobile applications and end-to-end web features. Implement front-end interfaces, back-end services and RESTful APIs, optimize databases, write tests and documentation, perform code reviews, and collaborate with UX, QA, and DevOps to deliver high-quality, secure, and performant solutions.
Top Skills: .NetAngularCSSGitHTMLJavaJavaScriptMySQLNode.jsNoSQLPHPPostgresPythonReactRestful ApisSQL ServerTypescriptVue
Reposted 2 Days AgoSaved
Remote
Remote Houston, TX
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Artificial Intelligence • Fintech • Software • Automation
Design, build, and optimize scalable backend services, APIs, and data pipelines. Integrate with third-party billing/commerce systems, maintain serverless/event-driven architectures on AWS, ensure security and performance, implement automated tests and CI/CD, mentor engineers, and drive architectural decisions.
Top Skills: Aws Api GatewayAws DynamodbAws LambdaAws S3Ci/CdEvent-Driven ArchitectureFlaskInfrastructure-As-CodeMySQLNode.jsPostgresPythonRestful ApisServerlessTest-Driven Development
Reposted 2 Days AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Angel or VC Firm • Fintech • Financial Services
Design, develop, and improve scalable software for an investment platform. Lead software development across the lifecycle, mentor junior engineers, solve complex technical problems, maintain code quality through testing and reviews, and recommend technology enhancements. The role is remote in the USA with four in-person retreats annually.
Top Skills: C#JavaPython
Reposted 2 Days AgoSaved
Remote
Remote Houston, TX
Junior
Junior
Artificial Intelligence • Information Technology • Software • Automation
Join a remote engineering team to write, test, and maintain code under senior guidance; participate in code reviews, standups, and sprint planning; debug and resolve application issues; and continuously learn new technologies and best practices.
Top Skills: GitGoJavaJavaScriptPython
Reposted 2 Days AgoSaved
Remote
Remote Houston, TX
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Fintech • Software • Automation
Lead and grow the Product Engineering team to deliver customer-facing web dashboards, APIs, integrations, and AI workflows. Own roadmap execution, collaborate with Product and Design, drive engineering best practices (testing, deployment, observability), provide technical mentorship, and remain hands-on in architecture and code reviews to ensure high-quality, scalable SaaS product delivery.
Top Skills: FastapiPostgresPythonReactTypescript
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