Top Remote Python Jobs in Houston, TX

Owns and optimizes resilient, ultra-low-latency network and physical data-center infrastructure for institutional trading across cloud and on-premises environments. Designs routing, multicast, segmentation, firewall, VPN, telemetry, and automation systems. Leads production changes, incident response, failover testing, maintenance, and on-call support for 24/7 trading platforms. Mentors engineers and partners with SRE, product, and trading-system teams to improve reliability and developer velocity.

Lead and mentor the software engineering team responsible for PSA Set Registry, a large-scale consumer web and mobile product. Drive architecture, development, delivery, code quality, release management, production troubleshooting, and technical strategy. Partner with product, design, and business teams to translate requirements into scalable solutions while promoting agile practices, collaboration, continuous learning, and an inclusive engineering culture.

Design and operate scalable, secure, highly available AWS infrastructure for a revenue management platform. Build infrastructure automation, CI/CD tooling, monitoring, and developer tools; advise on architecture, improve reliability and security, troubleshoot 24/7 incidents, lead root cause analyses, support AI-enabled DevOps workflows, and mentor engineers. The role participates in a weekly on-call rotation and is remote in the US or Canada.

Own the enterprise architecture vision for scalable, high-performance, cost-efficient multi-tenant SaaS systems. Lead AWS cloud optimization, distributed data and AI infrastructure, architectural governance, and Architecture Review Council activities. Guide engineering teams on microservices, event-driven systems, automation, and cloud-native practices while driving GenAI adoption across the software lifecycle. Build prototypes, establish architectural standards, optimize total cost of ownership, and mentor technical leaders.

Designs, operates, and improves AWS and Azure cloud infrastructure supporting customer-facing higher education products. Owns Kubernetes platforms, infrastructure as code, deployment automation, CI/CD, monitoring, security, reliability, disaster recovery, and cost optimization. Troubleshoots complex infrastructure and application issues, leads incidents, participates in on-call rotations, mentors engineers, contributes to technical standards, and partners across Development and Information Security on modernization and production readiness.

Build and own healthcare product surfaces end to end, from user discovery and interface design through API development, deployment, measurement, and migration from Salesforce or Athena. Work across React/TypeScript and Python/FastAPI on AWS, apply AI agents and LLM features, collaborate directly with clinicians and coordinators, and ensure rigorous handling of PHI, access control, and HIPAA-sensitive workflows.

Own web compatibility triage and incident response across DuckDuckGo browsers on Mac, Windows, iOS, and Android. Debug complex web applications and third-party code, distinguish site, browser, and privacy-related issues, reverse-engineer obfuscated code, build durable cross-platform fixes, and develop automation and LLM agent tooling to reproduce and triage breakage. Lead ambiguous projects independently and communicate with technical and non-technical stakeholders.

Develop and maintain Python-based software applications integrating with hardware, sensors, peripherals, and single-board computers. Responsibilities include software design, testing, debugging, GUI development, hardware interfaces, system integration, documentation, troubleshooting, prototyping, and deployment support for government and mission-focused customers. The role is hybrid/remote-friendly and suited to an early-career or journeyman developer with approximately 2–5 years of experience.

Paid six-week remote internship supporting government data infrastructure. Responsibilities include building and maintaining web scrapers and ingestion pipelines, researching data sources, validating data quality, monitoring source failures, improving scraper resilience, and documenting extraction logic. The role uses TypeScript, Python, browser automation, APIs, structured data formats, Git, and AI-assisted tooling.

Maintain and improve a complex healthcare platform spanning rules engines, applications, orchestration, event streaming, and data pipelines. Diagnose production issues, improve reliability, observability, performance, and scalability, implement focused features, write tests, participate in reviews, support on-call incident response, and lead root-cause analysis. Collaborate with delivery and decision intelligence teams to assume long-term ownership of platform components.

Build and maintain end-to-end features across backend (Node.js/TypeScript, Python) and frontend (React/TypeScript). Model Postgres schemas, integrate queues (QStash/Upstash), deploy on Cloudflare edge, write tests, enforce CI/CD, and harden systems for security and performance in regulated environments.

Build end-to-end user features under senior guidance: implement REST endpoints in Node.js/TypeScript, microservices in Python, maintain PostgreSQL schemas, process background jobs with QStash/Upstash, deploy to Cloudflare Workers/Pages/R2, write tests, and collaborate with product/design on React UI components.

Lead technical strategy, build and maintain software systems using AI, mentor early-career engineers, collaborate across disciplines, and protect user privacy and security. The role involves developing scalable systems on AWS and Kubernetes while working with healthcare data and adhering to HIPAA and data-security best practices.

Lead architecture and roadmap for a company-wide data lakehouse platform. Build platform-as-product components (SDKs, CLIs, control planes), optimize distributed compute/storage, prototype performance R&D, ensure compliance-by-design (lineage, PII masking, access control), enable real-time AI data ingestion, drive engineering standards, and mentor cross-functional teams.

Forward Deployed Engineer embedded with strategic customers to design and operate large-scale data infrastructure, troubleshoot distributed systems and networking issues, develop automation and APIs, and translate deployment challenges into product improvements. The role requires deep expertise in storage, Linux internals, high-performance networking, Python and C/C++, plus customer-facing communication and up to 25% travel.

Design, build, and scale backend services, APIs, and workflow systems supporting healthcare claims identification and recovery. Integrate AI/ML models, legal datasets, and transactional data while developing fault-tolerant Temporal workflows. Maintain AWS infrastructure and secure deployment pipelines using Python, TypeScript, PostgreSQL, Redis, and related technologies. Collaborate with product, business, and data science teams to deliver reliable, secure, high-performance systems in a regulated startup environment.

The Principal QA Architect owns the strategy, architecture, delivery, and adoption of enterprise QA technology solutions. Responsibilities include designing automation frameworks, AI-enabled testing capabilities, reporting, observability, test data solutions, CI/CD quality gates, and integrated platforms. The role remains hands-on with software development, prototyping, integrations, and troubleshooting while providing technical leadership, mentoring, roadmap ownership, stakeholder influence, and outcome measurement across QA and software delivery teams.

Administer identity, Google Workspace, email security, endpoint management, networking, SaaS applications, and cloud IAM for a distributed organization. Serve as the US escalation point for IT Support, manage onboarding and offboarding, conduct access audits, support acquisitions and platform consolidations, automate recurring tasks with scripts and APIs, coordinate security-provider activities, and maintain infrastructure documentation and runbooks. The role owns the New York office network and infrastructure projects end to end.

Build and maintain core digital banking experiences for bank administrators and customers. Responsibilities include developing user flows, robust REST APIs, backend services, and third-party integrations such as Plaid and SendGrid. The role emphasizes clean, tested, documented code, system design, error handling, logging, domain-driven design, microservice architecture, agile Scrum practices, architectural decision-making, technical guidance, and code reviews.

Own and evolve high-scale backend and data-layer services. Design, build, test, and operate distributed backend services and APIs, improve reliability/latency/scale, take end-to-end ownership from design through production support, participate in on-call and incident response, and mentor peers while partnering with Product and SRE teams.

Lead technical direction for Elastic’s core billing platform across cloud providers. Design and operate scalable billing systems, data pipelines, APIs, and PostgreSQL architecture. Improve reliability, observability, incident response, deployment, and CI/CD practices. Partner with SRE, Cloud Infrastructure, Product, Design, and Finance teams, guide architecture and roadmap decisions, review technical work, mentor engineers, and participate in on-call rotations.

Design, build, and optimize scalable cloud and web software with focus on infrastructure, performance, and hardware integration for IoT devices. Collaborate with hardware teams to ensure connectivity and high availability, implement new features, and improve system efficiency.

Develop and deploy a cloud-ready PostgreSQL/PostGIS database, Python REST APIs, ETL workflows, React interfaces, dashboards, and GIS visualization tools for the USGS Volcano Hazards Program. Ensure accessibility, security compliance, documentation, testing, and interoperability across volcano observatories. Collaborate with government stakeholders, support federal certification activities, and participate in up to three onsite visits during the 12-month engagement.

Own and modernize Domino's Tempest scale-testing platform; build repeatable automated validation, sizing guidance, and cloud-scale test automation; partner with platform teams to enable multi-cloud scale testing and improve test reliability and reporting.

Provides senior technical leadership for enterprise systems and telecom architecture. Establishes standards, approves designs, evaluates vendor solutions, develops technology roadmaps and capital plans, oversees testing and operational readiness, and guides complex projects across their lifecycle. Serves as a subject matter expert and liaison among engineering, product, program, capacity, leadership, and vendor teams while ensuring highly available, scalable, secure, and reliable network infrastructure.