Top Senior Machine Learning Jobs in Portland, ME

Build and deploy LLM-powered agents, workflows, and production integrations using platform templates, pipelines, and guardrails. Develop and run evaluation suites, integrate business systems and data sources, instrument cost and quality telemetry, and collaborate with business users to iterate within bounded scopes. The role requires strong Python and TypeScript, API development, prompt and context engineering, and production experience with agents, RAG, and tool use.

Build and deploy LLM-powered agents and workflows using templates, pipelines, and guardrails. Develop comprehensive evaluations, integrate AI solutions with business systems and data sources, and instrument applications for cost and quality telemetry. Collaborate with business users to iterate within defined scopes. The role requires strong Python and TypeScript skills, production experience with LLM applications, API development, prompt and context engineering, retrieval, and healthcare data handling.

Lead development of new credit line management programs by designing, testing, and scaling policies. Own end-to-end analytical work using SQL/Python, partner with Data Science and Product, and present data-driven recommendations to senior stakeholders to improve spend recovery, utilization, and line-management performance.

Lead the integration of AI and digital solutions in manufacturing processes, driving adoption and measurable impact on efficiency, quality, and performance.

As a Senior Machine Learning Engineer, you will enhance diffusion models, conduct research, collaborate on system implementations, and communicate findings effectively.

The Principal Product Manager - Growth will lead growth initiatives, focusing on user engagement, retention, and the use of AI to enhance product strategies and experiences.

Design, build, and deploy machine learning systems for controlling quantum processors. Develop reinforcement learning and Bayesian methods for QEC calibration, and work cross-functionally with product and R&D teams.

The Senior Technical Architect will lead AI SDLC transformations, create architectural solutions, mentor teams, and drive innovation in regulated industries.

As a Regional Sales Director, you'll lead a sales team, develop business plans, and drive sales growth by managing complex cycles and nurturing talent.

Own the full lifecycle of clinical text extraction models, from problem framing and annotation strategy through production deployment, evaluation, monitoring, and retraining. Build clinical NLP pipelines, establish defensible quality and error-analysis systems, and apply LLMs using rigorous evaluation, observability, and cost controls. Partner with clinical data and backend engineering teams while addressing PHI protection, de-identification, auditability, and access controls. As the first ML hire, set technical direction and potentially build and lead the future ML team.

Lead end-to-end product strategy and delivery for a core marketplace area, collaborating with engineering, UX, and design. Conduct qualitative and quantitative research, run agile sprints, measure results with analytics, and pioneer AI/ML product features and workflows to improve user experience and platform impact.

Lead document-vision research and production systems for multimodal legal evidence understanding. Define evaluation standards, frame hard problems, design and ship models, run efficacy studies and monitoring, mentor senior scientists, and advise leadership on scientific direction.

Lead development and application of analytics, statistical models, and dashboards to support R&D Quality oversight. Integrate clinical, safety, lab, and operational data to identify risks, support audit/inspection readiness, enable RBQM, and provide actionable quality insights and recommendations to cross-functional partners.

Lead strategic vision and execution of next-generation bioinformatics technologies. Identify and evaluate emerging computational methods, translate research into production-grade pipelines and prototypes, support product roadmaps and technology transfer, and partner cross-functionally to commercialize genomic and AI-driven healthcare solutions.

Provide senior legal and regulatory counsel for digital health and medical device products (SaMD), guiding product lifecycle, FDA and global filings, AI-enabled features, labeling, compliance, post-market obligations, and cross-functional governance. Lead strategy, manage external counsel, and translate regulatory developments into business guidance.

Develop and scale machine learning training systems for robotics data, optimize training pipelines, and collaborate with ML researchers to enhance autonomy models.

Lead design, development, and production deployment of ML and algorithmic solutions. Own end-to-end ML systems, support distributed production reliability, communicate tradeoffs, and apply generative AI, LLM fine-tuning, RAG, and agentic techniques to product problems.

Senior individual contributor responsible for leading pet/P&C insurance pricing model development (GLMs and ML), owning end-to-end projects, performing EDA and root-cause analysis, communicating results to stakeholders, and mentoring junior team members.

Responsible for fine-tuning state-of-the-art LLMs, optimizing models for deployment, and driving AI architectural decisions. Collaborate with cross-functional teams to develop impactful AI products.

Build and maintain scalable ML and generative AI platforms and backend infrastructure; deploy and manage production applications; create services exposing ML/AI products; implement RAG solutions and vector databases; integrate LLM orchestration and foundation model APIs; collaborate cross-functionally and mentor teammates.

Lead development of an AI-enabled Ethereum Layer 2 platform: build front-end and back-end systems, deploy and optimize AI models, create data pipelines, collaborate on model training, and contribute to product innovation and other company projects.

The Manager of RevOps/Yield analyzes patterns and data to optimize ad operations, manage vendor relationships, and oversee a remote team for revenue generation.

Embed with clients to gather requirements and design AI-driven solutions for fraud and fincrime. Architect, train, evaluate, and deploy custom AI agents and workflows, optimize model performance, establish risk metrics and evaluation pipelines, and collaborate with engineering/product teams to scale into production.

Own Oscilar's AML product suite (transaction monitoring, KYC/KYB, screening, case management, SAR filing, AI agents). Define detection rules, model calibration, data strategy, and defensible audit trails. Collaborate with engineers and compliance, use AI across discovery/design/analysis, deliver PRDs, validate models, and ship production features.

Lead end-to-end research applying advanced ML/DL (transformers, GNNs, RL, ensembles) to generate alpha across digital asset markets, build production-grade pipelines, prevent leakage/overfitting, analyze microstructure and on-chain data, and mentor junior researchers.