Top Senior Software Engineer Jobs in Louisville, KY

Reposted 14 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Information Technology • Software • Analytics
The Senior .NET Developer will work on developing and maintaining applications, mentor junior developers, and ensure compliance with regulations. The role requires expertise in full-stack development, particularly with SQL Server databases and Azure.
Top Skills: .Net.Net MvcAzureAzure DevopsC#CSSEntity FrameworkHTMLJavaScriptLinqSQL ServerVisual Studio
Reposted 14 Days AgoSaved
Remote
Louisville, KY
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Cybersecurity
The Senior Fullstack Software Engineer will design, implement, and maintain features for Conveyor's SaaS platform, involving both backend and frontend work, while collaborating closely with team members and mentoring juniors.
Top Skills: AWSPostgresPythonReactRestful ApisRuby On Rails
Reposted 14 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Blockchain • Fintech • Payments • Financial Services
The Senior Backend Software Developer will develop scalable systems using Node.js and MongoDB, collaborate with teams, ensure code quality, mentor developers, and stay updated on technologies.
Top Skills: MongoDBNode.js
Reposted 14 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Blockchain • Software
Design, build, and maintain scalable end-to-end systems and APIs/SDKs for an enterprise custody platform. Work full-stack across databases, cloud deployments, CI/CD, and security; troubleshoot issues, integrate emerging technologies, and mentor junior engineers.
Top Skills: AWSAzureC++Ci/CdDevOpsDockerEncryptionGCPJwtKubernetesMongoDBMySQLNode.jsOauthPostgresPythonRedisRestRust
Reposted 14 Days AgoSaved
Remote
Louisville, KY
175K-210K Annually
Senior level
175K-210K Annually
Senior level
Greentech
Develop and enhance software solutions for mineral exploration, collaborating with geologists and data scientists, and driving insights from data systems.
Top Skills: AWSDjangoPrefectPythonReactRetool
Reposted 14 Days AgoSaved
Remote
Louisville, KY
150K-185K Annually
Senior level
150K-185K Annually
Senior level
Aerospace • Manufacturing
The Senior Backend Software Engineer will develop and optimize critical systems for the aerospace industry, managing project priorities and overseeing various software projects.
Top Skills: C/C++Cloud InfrastructureContainer OrchestrationDistributed Data SystemsGoJavaRust
Reposted 14 Days AgoSaved
Remote
Louisville, KY
150K-185K Annually
Senior level
150K-185K Annually
Senior level
Aerospace • Manufacturing
Seeking an experienced Software Engineer for the Spacetime team to develop systems for satellite communication, requiring expertise in algorithms and large-scale distributed systems.
Top Skills: C++Cloud InfrastructureContainer OrchestrationDistributed SystemsGoJavaRust
Reposted 14 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
Lead the development of analytics infrastructure for clinical AI/ML products, focusing on product performance monitoring, data management, and cross-functional collaboration.
Top Skills: AWSDbtPythonQuicksightSQLTableau
Reposted 14 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
Lead and optimize enterprise client implementations, develop frameworks for efficiency, conduct end-to-end testing, and collaborate across teams to drive impactful technology in healthcare.
Top Skills: AWSAzureMySQLPostgresReactTypescript
Reposted 14 Days AgoSaved
Remote
Louisville, KY
120K-200K Annually
Senior level
120K-200K Annually
Senior level
Software
The Senior Bilingual Software Engineer will align U.S. teams with the Platform Core team in Japan, focusing on high-impact problems and maximizing platform leverage through clear communication and collaboration.
Top Skills: APIsBackend SystemsComposable ArchitecturesData ModelsDistributed TeamsErpGoModern Software ArchitectureRustSaas IntegrationsSoftware EngineeringSupply Chain SystemsSystem DesignTypescript
Reposted 14 Days AgoSaved
In-Office or Remote
Louisville, KY
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Reposted 15 Days AgoSaved
Remote
Louisville, KY
106K-132K Annually
Senior level
106K-132K Annually
Senior level
Biotech
The Software Engineer III - Voice AI develops and maintains the Voice AI platform for patient calls, optimizing real-time conversational AI features and mentoring team members.
Top Skills: AWSDynamoDBKafkaMySQLNode.jsRedisTwilioTypescript
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15 Days AgoSaved
Remote
Louisville, KY
80K-90K Annually
Senior level
80K-90K Annually
Senior level
Agency • Artificial Intelligence • Enterprise Web • HR Tech • Consulting
Design, build, and maintain scalable full-stack web applications. Implement backend APIs and responsive frontends, deploy to cloud, ensure security/performance, write tests, debug issues, participate in reviews, and mentor junior developers.
Top Skills: .NetAgile/ScrumAWSAzureC#Ci/CdCSS3DjangoDockerFastapiFlaskGitHTML5JavaJavaScriptKubernetesLlm ApisMongoDBNext.JsNode.jsPostgresPythonReactRestful ApisSpring BootSQLTypescriptWebsockets
20 Days AgoSaved
Easy Apply
Remote
Louisville, KY
Easy Apply
218K-257K Annually
Senior level
218K-257K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Design, build, and operate backend systems for prediction markets, including order management, trade matching, settlement, and market resolution. Architect distributed, low-latency systems with strict financial correctness, lead multi-quarter technical projects, mentor engineers, and collaborate with Product, Compliance, and Risk to meet regulatory requirements.
Top Skills: Generative AiGoJava
21 Days AgoSaved
Easy Apply
Remote
Louisville, KY
Easy Apply
186K-219K Annually
Senior level
186K-219K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Build and maintain multi-cloud infrastructure standards, self-service tooling, and paved-road defaults across AWS and GCP. Partner with compute, security, and networking teams to embed guardrails, drive standardization, lead cross-team initiatives, and resolve systemic operational issues to ensure secure, scalable, and reliable platform infrastructure.
Top Skills: AWSDnsGCPGenerative AiGoLoad BalancersPulumiPythonTerraformTransit GatewaysVpc
21 Days AgoSaved
Easy Apply
Remote
Louisville, KY
Easy Apply
186K-219K Annually
Senior level
186K-219K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Design, build, and own backend services for prediction markets across market lifecycle: creation, trading, oracle resolution, settlement, and payouts. Build low-latency, high-throughput microservices and event-driven systems, drive reliability via SLOs and observability, lead incident response, set technical standards, and mentor engineers while partnering cross-functionally to deliver product and compliance-aligned roadmaps.
Top Skills: Distributed SystemsEvent-Driven ArchitecturesGenerative AiGoIncident ResponseJavaLow-Latency SystemsMicroservicesObservabilityPythonRubySlos
21 Days AgoSaved
Remote
Louisville, KY
241K-283K Annually
Senior level
241K-283K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
Serve as the technical IC leader for the Provider organization: set technical roadmap and engineering standards, design and review architectures, drive cross-team initiatives, mentor engineers, and deliver high-throughput, low-latency, cloud-based microservice systems for provider-focused products.
Top Skills: Cloud InfrastructureDistributed SystemsMicroservicesNoSQLSQL
Reposted 21 Days AgoSaved
Remote
Louisville, KY
125K-175K Annually
Senior level
125K-175K Annually
Senior level
Edtech • Professional Services • Conversational AI
Hands-on senior full-stack engineer building and supporting user-facing features, infrastructure, and AI-powered workflows (LLM integration, RAG, agents). Drive architecture, dev experience, CI/CD, and partner with product and program teams to deliver a scalable education platform.
Top Skills: AWSJavaScriptLlm ApisTypescript
Reposted 15 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Software
As a Senior Implementation Engineer, you'll own technical projects, enhance the Java codebase, automate processes, integrate systems, and collaborate with customers on infrastructure design.
Top Skills: AWSBashGithub ActionsJavaPostgresPythonSQL
Reposted 15 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Edtech
Seeking a Senior DevOps Engineer for OpenSesame, focusing on CI/CD pipelines, cloud infrastructure, and automation. Responsibilities include improving developer experience and mentoring teams.
Top Skills: AWSC#ChefDockerGithub ActionsGoPHPPythonTerraform
Reposted 15 Days AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Information Technology • Consulting
The Senior HPC Cluster Engineer will optimize GPU clusters, troubleshoot InfiniBand networks, integrate new hardware, enhance automation systems, and manage GPU devices in HPC environments.
Top Skills: C/C++GoGpuInfinibandKubernetesKvmLinuxMpiNcclPythonPyTorchQemuRdmaRoceTensorFlow
21 Days AgoSaved
Easy Apply
Remote
Louisville, KY
Easy Apply
218K-257K Annually
Senior level
218K-257K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Design, build, and launch reliability engineering projects to scale production services. Improve scalability, observability, secrets/configuration management, canary-based deployments, and deployment safety. Partner with teams, support critical services, participate in on-call rotations, and promote reliability best practices.
Top Skills: AWSAzureDatadogGCPGenerative AiGoKibanaRubyTerraform
21 Days AgoSaved
Easy Apply
Remote
Louisville, KY
Easy Apply
186K-219K Annually
Senior level
186K-219K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Own end-to-end frontend development for core crypto payment flows across web and mobile. Improve latency, availability, and SLOs; build user-facing features (contacts, real-time transaction status); identify and fix performance bottlenecks; partner with product/design/backend; mentor junior engineers to reduce customer friction at scale.
Top Skills: Generative AiReactReact Native
21 Days AgoSaved
Remote
Louisville, KY
170K-300K Annually
Senior level
170K-300K Annually
Senior level
Healthtech • Pet
Lead design and delivery of major product areas across web and mobile. Build and improve React/React Native apps, design scalable systems and data models, optimize performance, mentor engineers, set engineering standards, and collaborate with cross-functional stakeholders in a fully remote environment.
Top Skills: ClickhouseDjangoDjango Rest FrameworkElasticsearchGitJavaScriptLess.JsPostgresPythonReactReact NativeReact-QueryRedisTypescript
21 Days AgoSaved
Remote
Louisville, KY
173K-203K Annually
Senior level
173K-203K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
Build and scale full-stack systems to improve provider onboarding and supply; design distributed, maintainable services; lead high-priority projects; mentor engineers; integrate AI-assisted and LLM-based features; drive provider-facing product quality and reliability.
Top Skills: AWSCi/CdClaude CodeCursorDockerGCPGithub CopilotKubernetesLlm/Agentic WorkflowsNode.jsPostgresReactTypescript
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