Top Senior IT Jobs in Louisville, KY

Design, train and validate supervised ML models on multi-billion claim records to score fraud risk; engineer features in-warehouse; deploy and monitor models in production; provide human-readable rationale and claim-level evidence; collaborate with subject-matter experts and stakeholders to ensure actionable, explainable outputs.

Lead commercial strategy and execution for IT spend categories (SaaS, cloud, endpoint, telecom). Manage renewals, run competitive sourcing events, negotiate pricing and contract terms, build TCO and spend analysis, coordinate legal and security reviews, maintain vendor frameworks, and align cross-functional stakeholders to deliver savings and reduce vendor risk.

Perform end-to-end FedRAMP assessments for cloud service providers: interview SMEs, review IaaS architectures (AWS/Azure/OCI), validate NIST SP 800-53 controls, analyze vulnerabilities, verify encryption and configurations, draft deliverables, and mentor project team members.

Perform end-to-end FedRAMP assessments: interview CSP SMEs, walkthrough cloud architectures (AWS/Azure/OCI), evaluate NIST SP 800-53 controls, validate configurations and vulnerabilities, draft deliverables, train and mentor team members, and support practice development.

Lead and facilitate OPTN committee operations including meeting planning, governance documentation, policy development support, stakeholder coordination, training, and data analysis to ensure compliance with HRSA and federal regulations.

Operate and improve IJM's Microsoft Azure environment: ensure availability, performance, security, monitoring, incident response, cost optimization, IaC deployments (Bicep/ARM/Terraform), automation with PowerShell/Azure CLI, governance (Azure Policy/RBAC), and collaborate across teams to maintain standardized, secure, and observable cloud platforms.

Facilitate IT demand intake, evaluate and prioritize requests, ensure decision-ready business cases, maintain demand/portfolio visibility, coordinate risk and compliance assessments, manage resource capacity and sequencing, and partner with PMO and stakeholders to optimize IT delivery and governance.

Senior Business Systems Analyst combining strategic enterprise planning with hands-on functional analysis to drive cloud modernization and process transformation. Translate executive priorities into roadmaps, define complex functional requirements, perform capability modeling, support delivery and testing, and present recommendations to senior stakeholders.

Design, deploy, and manage scalable, secure cloud infrastructure. Implement networking, VMs, IaC, and configuration management. Integrate Azure infrastructure into CI/CD pipelines, automate provisioning with DevOps/GitHub Actions, and enforce security/compliance with security teams. Provide Windows Server administration and support enterprise cloud initiatives.

Perform financial analyses for IT, develop Total Cost of Ownership and forecasting models, and recommend financial strategies. Support IT operations/governance, integrate financial checkpoints into governance, and apply Agile delivery principles to align services and outcomes.

Lead and continuously improve the global IT Compliance function for a CRO, ensuring IT governance, ISMS and ISO 27001 certification support, GxP computerised system compliance, audit readiness and vendor/third-party compliance oversight. Provide regulatory guidance, manage audit responses, run risk assessments, maintain compliance documentation, and drive remediation and continual improvement across IT and business stakeholders.

Serve as Product Owner for Oracle/Cerner clinical solutions, partnering with stakeholders to define workflows, write user stories, manage backlogs, configure systems, support enterprise deployment and adoption, and provide SME through the product lifecycle. Requires risk mitigation, cross-team collaboration, and occasional travel.

Serve as strategic advisor to assess and optimize end-to-end hospital revenue cycle operations using Epic workflows. Lead performance improvement, analytics, change management, compliance, and operational initiatives to improve financial and patient financial experience.

Provide senior-level remote IT support and operations for a distributed workforce: troubleshoot macOS/Windows/Linux/mobile, manage onboarding/offboarding, administer identity (Rippling/Okta) and MDM, maintain asset inventory, build AI-driven automations (Console.com, Risotto, Unthread), support SOC 2/HIPAA/ISO compliance, write runbooks in Notion, and contribute to the IT roadmap while mentoring the team.

The Senior IT Program Manager leads program development and implementation, ensuring projects align with business needs and are delivered on time and budget. They manage stakeholder relationships and facilitate communication with senior leadership, oversee financial management, and develop risk management strategies.

Lead and execute IT audit and assurance engagements (SOX, SOC 1, SOC 2), perform ITGC/ITAC and automated controls testing, prepare workpapers and RCMs, provide technical guidance to clients, and mentor junior team members while contributing to practice development.

Serve as first-line IT support for hardware, software, networking, and enterprise applications. Triage and resolve support tickets, manage onboarding/offboarding, administer Okta and endpoint management (Intune, Jamf), maintain device health and access controls, collaborate with Security and Engineering, document processes, and improve support workflows to ensure a secure, compliant, and user-friendly hybrid work environment.

The role involves designing and developing enterprise-grade software solutions, integrating AI tools, collaborating with teams, and maintaining documentation while enhancing productivity for Yahoo personnel.

Lead strategy, delivery, and operations of the organization's Workday ERP platform across Finance, HR, Supply Chain and related applications. Oversee integrations, security, reporting, release management, vendor relationships, governance, service management, data integrity, and end-user adoption to drive continuous improvement and enterprise value.

Design and guide secure, scalable enterprise and cloud architectures (DNS, Azure, AWS, on-prem). Lead cloud migrations, implement monitoring, integrate hybrid environments, present technical briefings, and mentor staff while ensuring security and performance for a mission-focused government client.

Lead Data QA for the Enterprise Data Warehouse: define QA strategy, design and execute source-to-target validations, CDC and ETL checks, data masking verification, build quality dashboards and automations, mentor QA analysts, manage defects and release readiness, and collaborate with Data Engineering, BI, Product, and stakeholders to ensure data is accurate, complete, and audit-ready.

Senior IT leader partnering with Commercial leadership to define and deliver pharma commercial technology strategy, oversee Veeva and digital platforms, lead product launch technology readiness, manage vendors/agencies, ensure compliance and governance, and lead IT teams to deliver scalable, secure commercial applications and digital experiences.

The role involves leading the data governance team, managing IT projects, collaborating with stakeholders, and ensuring continuous improvement of processes. Responsibilities include strategic planning, client management, and optimizing resource utilization, while overseeing governance activities and departmental management.

Lead enterprise IT sourcing and software procurement for complex renewals and strategic sourcing initiatives. Drive savings, establish governance, create vendor strategies and KPIs, partner with IT and stakeholders, mentor procurement staff, and manage contract negotiations and renewals.

Lead and mentor the Infrastructure team and deliver the enterprise infrastructure roadmap. Design and maintain resilient on-prem and cloud (Azure) network and server environments, oversee capacity planning, monitoring, backup/recovery, disaster recovery, vendor management, and infrastructure automation. Support ERP/Sage X3 infrastructure, collaborate with InfoSec on vulnerability remediation and OT teams for manufacturing environments, and manage infrastructure projects and on-call escalations.