Top Senior IT Jobs in Des Moines, IA

4 Days AgoSaved
Remote
Des Moines, IA
102K-138K Annually
Senior level
102K-138K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
The Principal Network Engineer implements and supports network infrastructure for a federal healthcare EHR modernization program. Responsibilities include cloud and VLAN network configuration, microsegmentation, OCI connectivity troubleshooting, routing strategy, cybersecurity policy alignment, ATO artifact collection, deployment support, change management collaboration, vendor capability implementation, and technical documentation. The role is remote, supports cross-functional teams, and requires obtaining and maintaining a Public Trust Level 5 clearance.
Top Skills: Cloud NetworkingFedrampMicrosegmentationNist 800-53Nist Cybersecurity Framework (Nist Csf)Oracle Cloud Infrastructure (Oci)Oracle Health Cerner MillenniumPpsmVirtual NetworkingVlanZero Trust Architecture
4 Days AgoSaved
Remote
Des Moines, IA
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Establishes and maintains enterprise data governance frameworks, standards, ownership models, privacy controls, metadata, quality monitoring, and stewardship practices. Partners with legal, security, privacy, records management, engineering, and business stakeholders to ensure compliant data use. The role identifies governance risks, supports audits and remediation, develops documentation and training, monitors program metrics, and contributes to governance roadmaps and maturity improvements for a federal courts modernization program.
Top Skills: AlationChange Data CaptureCloud Data PlatformsCollibraData CatalogsData IntegrationData ModelingMetadata ManagementQlik
4 Days AgoSaved
Remote
Des Moines, IA
133K-178K Annually
Senior level
133K-178K Annually
Senior level
Biotech
Leads the architecture, implementation, and governance of enterprise IAM and IGA solutions using SailPoint and ServiceNow. Designs integrations, provisioning workflows, access certifications, role management, and segregation-of-duties controls across enterprise systems. Provides technical leadership, conducts design reviews, mentors IAM teams, leads workshops, manages risks, and ensures GxP, SOX, security, compliance, and audit requirements are met.
Top Skills: Active DirectoryAWSAzureAzure AdBeanshellFieldglassGCPIdentity Governance And AdministrationJavaJdbcLdapMicrosoft 365Microsoft Entra IdOracle ErpRest ApisRole-Based Access ControlSailpoint Identity Security CloudSalesforceScimServicenowWorkday
4 Days AgoSaved
Remote or Hybrid
Des Moines, IA
Senior level
Senior level
Software
Designs and operates IT services for laboratory environments, including networks, compute, security, private cloud, and SDN platforms. Translates business and IT requirements into secure, standardized architectures and operational processes. Leads deployments, design reviews, documentation, incident gap analysis, automation, and infrastructure optimization. Requires extensive enterprise networking, datacenter, virtualization, Linux, security, and ITIL experience.
Top Skills: AutomationBgpDhcpDnsFortinetInfrastructure As CodeIpsecIpv6ItilLinuxNokia Service RoutersNokia Sr LinuxOpenshiftOpenstackOrchestrationOspfPalo Alto FirewallsPrivate CloudProxmoxQosSoftware-Defined Networking (Sdn)TlsVMwareVrrpVxlan
4 Days AgoSaved
Remote or Hybrid
Des Moines, IA
Senior level
Senior level
Software
Designs and operates laboratory IT services covering compute, networks, security, private and public cloud, and software-defined networking. Translates business requirements into secure, high-performance service offerings; defines architectures, configurations, processes, and operational procedures. Leads implementations, design reviews, documentation, incident analysis, gap remediation, automation, and infrastructure optimization across global laboratory environments.
Top Skills: AutomationBgpFortinetInfrastructure As CodeItilLinuxNokia Service RoutersNokia Sr LinuxOpenshiftOpenstackOrchestrationOspfPalo Alto FirewallsPrivate CloudProxmoxPublic CloudQosSoftware-Defined NetworkingVMwareVrrpVxlan
Reposted 4 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Healthtech
Lead an Automation Center of Excellence to build and maintain IaC, automation pipelines, and configuration management across colo and multi-cloud (Azure, GCP, OCI). Drive standardization, governance, security controls, CI/CD integration, incident management, GitOps and policy-as-code adoption. Mentor team members, manage vendor relationships, measure automation KPIs, and provide executive reporting. Participate in on-call rotation and work outside normal hours as needed.
Top Skills: AnsibleArmAzureAzure DevopsBicepCi/CdGcp Deployment ManagerGitGithub ActionsGitopsGoogle Cloud Platform (Gcp)Infrastructure As Code (Iac)JenkinsObservabilityOci Resource ManagerOracle Cloud Infrastructure (Oci)Policy-As-CodeSecrets ManagementTerraform
Reposted 4 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Healthtech
Lead and manage a virtualization team operating mixed VMware and Nutanix environments. Ensure availability, performance, security, upgrades, migrations, automation, capacity planning, incident management, vendor relations, KPIs, and alignment with cloud and business objectives.
Top Skills: AnsibleEsxiNutanix AhvNutanix FilesNutanix FlowNutanix MoveNutanix ObjectsNutanix PrismVdsVmware Aria OperationsVmware VsphereVsan
Reposted 4 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Healthtech • Information Technology
The Senior IT Risk and Compliance Analyst manages vendor risk, ensures compliance with regulations, documents controls, and supports risk mitigation efforts across IT teams.
Top Skills: Audit MethodologiesCobitIso27001Iso27002NistServicenow Irm
Reposted 4 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Healthtech
The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.
Top Skills: JIRAMs ProjectServicenow PpmSmartsheet
Reposted 4 Days AgoSaved
Remote or Hybrid
Des Moines, IA
138K-190K Annually
Senior level
138K-190K Annually
Senior level
Artificial Intelligence • Healthtech • Social Impact • Telehealth
Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.
Top Skills: AWSBashCi/CdGitGitGithub ActionsGoogle WorkspaceIamIpaasJamf ProJSONLambdaLinuxMicrosoft 365Microsoft IntuneOktaOkta WorkflowsPythonRest ApisWebhooksWorkato
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
111K-150K Annually
Senior level
111K-150K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead multi-cloud modernization projects for federal customers: define scope, maintain schedules, coordinate cloud/DevOps/network/security/data teams, manage risks and documentation, and drive continuous improvement using standard PM methodologies and tools. Remote role with limited travel.
Top Skills: AWSAzureCloud ModernizationDevOpsGoogle Cloud PlatformOracle CloudProject Management Tools
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Healthtech • Pharmaceutical
The IT Systems Engineer III will improve Ophelia's IT systems through integration, automation, and security while managing IT projects, overseeing service providers, and ensuring compliance.
Top Skills: AIDlpDns AdministrationEdrGoogle Cloud PlatformIdp/IamItsmMdmSAMLScimZtna
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Reposted 5 Days AgoSaved
Remote
Des Moines, IA
114K-199K Annually
Senior level
114K-199K Annually
Senior level
Other • Retail
Lead multiple AI engineering and innovation squads to design, build, and scale AI-powered products on Google Cloud. Translate AI strategy into roadmaps, provide technical leadership across architecture, DevSecOps, CI/CD, telemetry, and APM, manage budgets/vendors, hire and develop teams, and ensure production reliability, security, and measurable business value.
Top Skills: ApmAppdynamicsCi/CdData LoggingDatadogDevsecopsGCPGoogle Cloud PlatformIntegrationsJavaMicroservices (Msa)PythonService-Oriented Architecture (Soa)Telemetry
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
136K-184K Annually
Senior level
136K-184K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead implementation and ongoing management of ServiceNow Hardware and Software Asset Management and Software Bill of Materials capabilities. Collaborate with GDIT and AmeriCorps teams to capture and fulfill requirements, drive inventory management and control, and use ServiceNow and Azure technologies to support mission objectives.
Top Skills: AzureServicenowServicenow Hardware Asset ManagementServicenow Software Asset ManagementSoftware Bill Of Materials
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
115K-155K Annually
Senior level
115K-155K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Senior Database Analyst/Administrator responsible for database architecture, administration, performance, security, data modeling, warehousing, ETL, migration, and data integrity. Develops SQL Server database objects, dimensional models, enterprise data marts, BI dashboards, and Splunk monitoring reports. Collaborates with stakeholders to translate business needs into technical requirements, supports Agile development, conducts code reviews, and implements cloud and hybrid-cloud database solutions.
Top Skills: AgileAtlassian SuiteAzureBusiness IntelligenceCi/CdData WarehousingETLInformixOracleRelational Data ModelingSafeSnowflakeSplunkSQL ServerSql Server Management Studio
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
97K-131K Annually
Senior level
97K-131K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design, execute, and analyze performance, load, stress, and endurance tests for cloud-based enterprise applications. Build AWS test environments, create test scripts (JMeter/LoadRunner/NeoLoad/K6), integrate tests into CI/CD, analyze results, identify bottlenecks, validate scalability and resilience, and produce performance reports to ensure releases meet federal performance standards.
Top Skills: AWSCloudwatchConfluenceDatadogDockerEc2EcsElk StackGithub ActionsGitlab Ci/CdGrafanaJavaScriptJenkinsJIRAJmeterK6KubernetesLoadrunnerMicroservicesMs TeamsNeoloadNode.jsOpenshiftPower BIPrometheusRdsReactRest ApisSeleniumSharepointSQLTableau
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
68K-133K Annually
Senior level
68K-133K Annually
Senior level
Healthtech • Professional Services • Pharmaceutical • Telehealth
Administers and optimizes enterprise endpoint computing, virtual desktop, identity management, clinical workspace, and Windows Server environments. Provides Tier 2 and Tier 3 support across more than 5,000 users and endpoints, managing Azure Virtual Desktop, Citrix, Okta, Entra ID, Active Directory, Microsoft 365, Imprivata, and IGEL. Responsibilities include troubleshooting, patching, access management, infrastructure maintenance, documentation, ITIL service operations, disaster recovery participation, process improvement, mentoring, and occasional on-call support.
Top Skills: Active DirectoryAzure Virtual DesktopCitrix Virtual Apps And DesktopsDhcpDnsFslogixGroup PolicyIgelImprivataItilMicrosoft 365Microsoft Entra IdOktaWindows 10Windows 11Windows Server 2016Windows Server 2019Windows Server 2022
5 Days AgoSaved
In-Office or Remote
Des Moines, IA
36K-128K Annually
Senior level
36K-128K Annually
Senior level
Agency • Information Technology
Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and other enterprise initiatives while coordinating cross-functional teams and multiple concurrent priorities.
Top Skills: AgileApplication ModernizationCloud TransformationScrumSdlcWaterfall
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
150K-187K Annually
Senior level
150K-187K Annually
Senior level
Fintech
Design and automate compliance systems to enhance efficiency in audit readiness. Collaborate with teams to integrate tools and optimize processes.
Top Skills: APIsBigQueryChatgptClaudeGCPGeminiGitPythonTerraform
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Telehealth
Lead global IT operations for a HIPAA-regulated healthtech company, managing a small support team and hands-on ticketing. Build and maintain systems for compliance and visibility, optimize vendor costs, implement security/onboarding processes, drive process improvements with KPIs and automation, and serve as primary IT liaison to leadership and partners.
Top Skills: Google WorkspaceJAMFJIRAOktaSaaS
Reposted 6 Days AgoSaved
Remote
Des Moines, IA
94K-115K Annually
Senior level
94K-115K Annually
Senior level
Cloud • Information Technology • Productivity • Security • Software
Serve as IT Infrastructure Project Manager for public sector clients, delivering networking, wireless, UC, and data center/security projects on time and within budget. Manage schedules, budgets, vendors, stakeholders, risks, QA, and multiple concurrent projects. Provide client-facing communication, financial reporting, and leadership of internal and external teams while ensuring project profitability and adherence to methodology.
Top Skills: Data CenterNetworkingProject Management SoftwareSecurityUnified CommunicationWireless
6 Days AgoSaved
Remote
Des Moines, IA
130K-161K Annually
Senior level
130K-161K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Designs, implements, and supports secure, scalable AWS and Azure infrastructure. Develops reusable Terraform and Ansible automation, CI/CD capabilities, and cloud infrastructure services. Configures cloud compute, storage, networking, databases, identity, security, monitoring, and backup solutions. Troubleshoots infrastructure and hosting issues, maintains technical and compliance documentation, and collaborates with customers and engineering teams using Agile and DevOps practices.
Top Skills: AnsibleAWSBashCi/CdGitIamLinuxAzurePowershellPythonRbacTerraformVpnWindows
Reposted 6 Days AgoSaved
Remote
Des Moines, IA
179K-242K Annually
Senior level
179K-242K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Provide senior technical leadership and architectural oversight for large-scale EHR ecosystems. Define enterprise engineering strategy and roadmaps, ensure interoperability, scalability, availability, and cybersecurity, lead architectural governance and incident RCA, mentor engineering teams, coordinate with product owners and integrators, evaluate emerging technologies, and support proposals and customer engagements.
Top Skills: AWSAzureCerner/Oracle HealthDicomEpicFhirHl7
Reposted 6 Days AgoSaved
Remote
Des Moines, IA
169K-233K Annually
Senior level
169K-233K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Lead a global IT support team, drive AI-first ITSM transformation (ServiceNow->Atomicwork), own ITSM processes and SLA governance, partner on JML/identity automation with Platform Engineering, manage vendors, run cross-functional programs, develop regional specialists, and participate in on-call escalations. Position requires East Coast timezone alignment and ~25% international travel.
Top Skills: Ai-Native ItsmAtomicworkConfluenceConsoleJIRAJsmOktaServicenowSlack
6 Days AgoSaved
Remote
Des Moines, IA
130K-170K Annually
Senior level
130K-170K Annually
Senior level
Healthtech
Designs scalable, secure technology solutions connecting business objectives with application, integration, data, cloud, and enterprise systems. Responsibilities include developing architectures and roadmaps, modernizing processes through automation, governing APIs and data flows, incorporating security and compliance, guiding engineering teams, evaluating vendors, and facilitating stakeholder discovery workshops.
Top Skills: AIAnalyticsAPIsAWSAzureCloud ServicesCRMData WarehousingEdiEnterprise Integration PlatformsETLGCPWorkflow Platforms
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