Top Senior IT Jobs in Des Moines, IA

YesterdaySaved
Remote
Des Moines, IA
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Big Data • Cloud • Hardware • Software • App development
Leads the architecture, design, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system blueprints, selects technologies, integrates distributed systems across on-premises, cloud, and hybrid environments, optimizes performance, resolves system issues, and ensures compliance with DoD requirements. Leads engineering teams, supports installation and migration at multiple locations, and documents architecture and implementation decisions.
Top Skills: Attribute-Based Access Control (Abac)AWSC#Cloud ComputingDistributed SystemsGCPHybrid CloudIcamJavaMicro-SegmentationMicroservicesAzureNetwork Access ControlOn-Premises SystemsPythonZero TrustZero Trust Network Architecture
YesterdaySaved
Remote
Des Moines, IA
158K-195K Annually
Senior level
158K-195K Annually
Senior level
Biotech
Owns and leads Regulatory IT systems supporting Global Regulatory Affairs and R&D. Responsibilities include maintaining technology roadmaps, managing system enhancements and implementations, overseeing vendors and releases, providing production support, delivering integrations, conducting data mapping and validation, and ensuring GxP, HIPAA, GDPR, and CCPA compliance. The role serves as the primary IT partner for regulatory business units, manages budgets, and coordinates cross-functional teams delivering regulated technology initiatives.
Top Skills: CcpaCder DirectComputer Software AssuranceComputer System ValidationEctd Submission SystemsEsg WebtraderEsubmission GatewayEudralinkGdprGxpHipaaIdmpIrisLorenz DocubridgeLorenz EvalidatorSdlcSporVeeva Vault PublishingVeeva Vault RegistrationsVeeva Vault RimVeeva Vault SubmissionsVeeva Vault Submissions ArchiveXevmpd
YesterdaySaved
Remote or Hybrid
Des Moines, IA
Senior level
Senior level
Mobile • Security • Software • Cybersecurity
Leads complex federal platform, cloud infrastructure, IT services, security, compliance, and disaster recovery initiatives. Coordinates AWS GovCloud infrastructure-as-code, deployment automation, observability, Zero Trust identity programs, FedRAMP High and DoD IL5 readiness, and operational resilience. Partners across Engineering, Security, Compliance, and Product to manage roadmaps, dependencies, risks, milestones, and audit readiness. The role also builds and mentors a Federal Platform Operations team and drives reliable, repeatable delivery practices.
Top Skills: Amazon EcsAmazon EksAmazon RdsAmazon S3AWSAws GovcloudAws IamAws LambdaChatgptClaudeDatadogGrafanaKeeperpamPrometheusScimTerraform
YesterdaySaved
Remote
Des Moines, IA
93K-126K Annually
Senior level
93K-126K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Designs and maintains automated testing frameworks, scripts, datasets, and tools for complex data-driven software. Develops test plans, performs exploratory, database, API, performance, and integration testing, and validates data accuracy across systems. Analyzes defects and test metrics, supports CI/CD pipeline integration, and collaborates with application teams to resolve issues. The role also uses Playwright, database scripting, cloud technologies, Agile practices, and generative AI tools to improve software quality and efficiency.
Top Skills: AWSAzureBashCi/CdGenerative AiGitGitlab CiGCPJenkinsJIRAJmeterJunitNode.jsOraclePl/SqlPlaywrightPostmanPowershellRest-AssuredSQLSQL ServerT-SqlTestngTypescriptXray
YesterdaySaved
Remote
Des Moines, IA
109K-147K Annually
Senior level
109K-147K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Deploys, hardens, troubleshoots, and modernizes Windows and .NET applications across on-premises environments and AWS. Responsibilities include Terraform infrastructure, CI/CD pipelines, SQL Server and Amazon RDS administration, load balancing, WAF configuration, observability, certificate management, automation, migrations, incident response, documentation, and collaboration with application owners. The role is remote but requires weekly onsite availability in Rockville, Maryland, and may involve occasional after-hours maintenance or outage troubleshooting.
Top Skills: .NetAmazon BedrockAmazon CloudfrontAmazon CloudwatchAmazon Ec2Amazon EcsAmazon QAmazon RdsAmazon Route 53Amazon S3AWSAws Certificate ManagerAws CloudtrailAws CodebuildAws Elastic Load BalancingAws IamAws LambdaAws Secrets ManagerAws Systems ManagerAws Systems Manager Patch ManagerAws Systems Manager State ManagerAws WafBashDatadogGitGithub ActionsIisKerberosLdapMicrosoft Sql ServerPowershellPowershell DscPythonSAMLTerraformWindows Server
Reposted YesterdaySaved
Remote
Des Moines, IA
98K-115K Annually
Senior level
98K-115K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Senior Cybersecurity Engineer to engineer and manage Tenable, Splunk, McAfee and other security tools; perform risk assessments, incident triage and coordination, system hardening, security posture assessments, develop security toolsets, and maintain awareness of threats and vulnerabilities in support of Department of State missions.
Top Skills: CrowdstrikeEndpoint ProtectionLinuxMcafeeSplunkSymantecTenableWindows
YesterdaySaved
Remote
Des Moines, IA
153K-207K Annually
Senior level
153K-207K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Designs and delivers secure, scalable cloud solutions across AWS and Azure for application, data, scientific, and research workloads. Partners with customers to translate requirements into architectures, develops Terraform infrastructure and automation, integrates DevOps and CI/CD capabilities, and manages solutions through implementation and transition to operations. Responsibilities include cloud networking, identity, security, monitoring, backup and recovery, troubleshooting, documentation, technical reviews, and collaboration within an Agile Cloud DevOps team.
Top Skills: Amazon Web Services (Aws)AnsibleGitAzurePositPowershellPythonRedcapTerraform
YesterdaySaved
Remote
Des Moines, IA
97K-131K Annually
Senior level
97K-131K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Leads functional and automated testing for complex modern, cloud-based applications. Develops test strategies, plans, cases, and automation for unit, API, integration, UI, performance, security, and regression testing. Validates Kafka-based workflows, microservices, serverless systems, data pipelines, and CI/CD releases. Partners with engineering and DevSecOps teams on defect prevention, security, observability, environment readiness, root-cause analysis, and operational quality. Maintains audit-ready documentation and communicates risks and recommendations to stakeholders.
Top Skills: Apache KafkaApplication Lifecycle Management (Alm)Automated TestingCi/CdClaude CodeDataflowDevsecopsDockerGemini Vertex AiGitlabJavaJavaScriptJenkinsKubernetesMicroservicesOpencodePub/SubPythonReactRedisServerless ApplicationsServicenowSQLVersionone
Reposted YesterdaySaved
Remote
Des Moines, IA
81K-98K Annually
Senior level
81K-98K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design and lead development of instructor-led, virtual, and hybrid software training. Collaborate with SMEs and agencies to create ADDIE-based curricula, ensure Section 508 compliance, produce webinars, web-based training, user guides and online help, and evaluate training effectiveness for USPS implementations.
Top Skills: AddieCurriculum DevelopmentEducational TechnologyInstructor-Led TrainingOnline Help SystemsSection 508User GuidesWeb-Based TrainingWebinars
Reposted YesterdaySaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Automation
Act as the technical lead for field sales, manage evaluations, deliver on-site and remote demos, prepare SOWs/RFIs/RFPs, respond to security questionnaires, train sales teams, and support sales across U.S. and Canada while maintaining client relationships and achieving technical sales targets.
Top Skills: AIAsset TrackingCloud ComputingHosted IpHubspotManaged SecurityMS OfficeNetworkingTelecommunicationsVirtualization
Reposted YesterdaySaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Automation
Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.
Top Skills: Ai-Driven SolutionsMiller Heiman Blue SheetsMiller Heiman Strategic SellingPacsReporting WorkflowRisSalesforce
Reposted 24 Days AgoSaved
Remote
Des Moines, IA
206K-216K Annually
Senior level
206K-216K Annually
Senior level
Fintech
Support risk assessment, audit planning, and oversight of audit management and staff. Provide advisory services and ensure compliance with standards.
Top Skills: Cloud TechnologiesComputer ScienceCybersecurityData ScienceEnterprise Data ManagementIdentity And Access ManagementInformation Technology
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Reposted 2 Days AgoSaved
Remote
Des Moines, IA
98K-127K Annually
Senior level
98K-127K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Develop and maintain ServiceNow ITSM solutions, including forms, flows, catalog items, integrations, workflows, business rules, and custom applications. Collaborate with product owners, process owners, platform engineers, Scrum Masters, and developers to define requirements and deliver quality solutions. Support Agile ceremonies, platform upgrades, patching, deployments, troubleshooting, debugging, and adherence to ServiceNow best practices. Apply prompt engineering, Now Assist, and agentic AI expertise.
Top Skills: Agentic AiAgile/ScrumItsmNow AssistPrompt EngineeringServicenow
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
170K-230K Annually
Senior level
170K-230K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design, implement, and maintain enterprise Identity Provider (IdP) and ADFS authentication/federation services for millions of users. Configure federation trusts, SSO, MFA, PKI/certificate-based auth, integrate applications/APIs, troubleshoot tokens/claims, support Zero Trust and high-availability architectures, produce technical documentation, and collaborate across cyber, AD, cloud, and application teams.
Top Skills: Active DirectoryActive Directory Domain Services (Ad Ds)Active Directory Federation Services (Ad Fs)Certificate-Based AuthenticationCots Authentication ProductsIdentity Provider (Idp)JwtLdapLinuxAzureMulti-Factor Authentication (Mfa)Oauth 2.0Openid Connect (Oidc)PkiSaml 2.0Smart Card AuthenticationWindows ServerWs-Federation
2 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Other
Leads business analysis for enterprise applications and reporting initiatives. Translates stakeholder needs into requirements and functional or technical specifications, partners with IT on scalable solutions, manages project scope and risks, maintains process documentation, supports UAT and change readiness, and drives process standardization. Establishes business analysis standards and best practices across a growing, multi-location organization.
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design, build, and maintain scalable ETL/ELT pipelines and analytics-ready data models using Python and SQL. Implement GitLab CI/CD, develop dashboards in Tableau/Power BI, perform data cleaning and analysis, support modeling and AI initiatives, document metadata, and mentor junior staff while collaborating with cross-functional teams to deliver actionable insights.
Top Skills: AirflowAWSCi/CdDatabricksEtl/EltGitGitlab Ci/CdJIRAMlflowNumpyOraclePandasPostgresPower BIPythonSQLTableau
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
119K-161K Annually
Senior level
119K-161K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead a remote analytics team to deliver dashboards, data products, and decision-support tools. Oversee project plans, stakeholder engagement, data platform modernization, ETL/automation, Tableau/Power BI deployments, statistical modeling, QA, metadata, and staff mentoring to support federal social service programs.
Top Skills: AWSConfluenceDatabricksEtl/EltGeospatial AnalysisJIRANon-Relational DatabasesPower BIPythonRRelational DatabasesSQLTableauTableau Prep
2 Days AgoSaved
Remote
Des Moines, IA
143K-190K Annually
Senior level
143K-190K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Leads strategy, solutioning, and writing for complex federal proposals valued at $25M to $1B+. Shapes win themes, ensures compliance, identifies risks, partners with capture and solution teams, improves proposal operations, and mentors proposal staff. Supports multiple pursuits, large IDIQs, task orders, and AI-enabled proposal workflows while tailoring technical and management volumes to customer priorities and evaluation criteria.
2 Days AgoSaved
Remote
Des Moines, IA
97K-131K Annually
Senior level
97K-131K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Supports back-office operations for an ICAM program, coordinating PMO documentation, deliverables, procurements, assets, onboarding, reporting, compliance tracking, and communications. Maintains agendas, action items, trackers, logs, status reports, and program artifacts while improving workflows and documentation standards. Serves as a coordination hub across program management, finance, engineering, contracts, and compliance. The role is fully remote and requires an active Secret clearance.
Top Skills: JIRAMicrosoft TeamsSharepoint
Reposted 2 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Retail • Sales
The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.
Top Skills: CertiniaCpqFinancialforcePower BISalesforceServicemaxSQLZuora
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
162K-219K Annually
Senior level
162K-219K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead cloud financial governance for a federal enterprise: manage chargeback/showback, cost optimization, forecasting, anomaly detection, procurement alignment, and executive dashboards to ensure VA fiscal policy compliance and large-scale cloud spend oversight.
Top Skills: Aws Cloud Financial ManagementAzure Cloud Financial Management
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
91K-159K Annually
Senior level
91K-159K Annually
Senior level
Other • Retail
Lead a team to design, build, and operate scalable, secure platform and MLOps capabilities on GCP and hybrid cloud. Drive DevSecOps, CI/CD, telemetry, and platform modernization to accelerate AI/ML and software delivery while managing delivery, budgets, vendors, and stakeholder alignment.
Top Skills: AppdynamicsAzureBigQueryCi/CdDatadogDevsecopsGoogle Cloud Platform (Gcp)JavaMlopsPythonVertex Ai
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
70K-115K Annually
Senior level
70K-115K Annually
Senior level
Consulting
The IT Project Manager will oversee project planning, implementation, and client interactions while ensuring compliance with federal and state regulations in the public sector.
Top Skills: AccessMS OfficeSpssSQL
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
88K-135K Annually
Senior level
88K-135K Annually
Senior level
Consulting
The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.
Top Skills: AgileBusiness IntelligenceCloud-Based ErpData AnalysisData MigrationIv&VPeoplesoftSap S/4Hana RiseSoftware DevelopmentWaterfall
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
274K-335K Annually
Senior level
274K-335K Annually
Senior level
Biotech
Lead global IT sourcing strategy and a multi-year technology modernization agenda. Manage $450M spend, strategic supplier relationships, governance, risk, and value delivery. Oversee category management (cloud, software, infrastructure, cyber), negotiations with hyperscalers and SaaS vendors, stakeholder engagement, and build a high-performing sourcing organization.
Top Skills: CloudCyberDigital ServicesErpHyperscalersInfrastructureSaaS
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