Top Senior IT Jobs in Des Moines, IA

The IT IMO Program Manager will lead IT and Cyber integration activities for a business acquisition, ensuring governance, coordination, and successful delivery across multiple workstreams.

The Manager of Internal Audit (IT) leads audit engagements, supervises staff, and develops risk-based audit schedules while ensuring compliance with regulatory standards.

The IT Systems Engineer III will improve Ophelia's IT systems through integration, automation, and security while managing IT projects, overseeing service providers, and ensuring compliance.

The Director of IT Business Enablement will lead partnerships with manufacturing leaders to drive technology strategies, optimize processes, and promote operational excellence across the organization.

Lead global IT business enablement for Manufacturing and Quality, forging partnerships, driving innovation, and ensuring operational excellence through technology.

The role leads IT Business Enablement, partnering with senior leaders to drive operational excellence in Manufacturing and Quality through technology and agile practices.

The role involves designing and developing enterprise-grade software solutions, integrating AI tools, collaborating with teams, and maintaining documentation while enhancing productivity for Yahoo personnel.

The Director of IT Applications leads the delivery of enterprise applications, ensuring that business systems effectively support operations across Finance, Sales, Marketing, HR, and more while driving automation and system improvements.

The Senior Network Engineer will design, implement, and secure global networking infrastructure, ensuring resilience and security across various environments. They will collaborate with IT, Security, and Engineering to support mission-critical operations and compliance with relevant frameworks.

Lead IT support operations, ensuring high-quality technical support, vendor management, and IT processes for a remote workforce while improving contributor experience.

The Senior Manager of Corporate Operations will lead technical strategy for internal systems, focusing on IAM, MDM, and corporate infrastructure, ensuring security and operational excellence across environments.

The IT Project Manager will oversee high-visibility projects, ensuring they stay on track regarding timeline, scope, and budget while gathering requirements and working within a PMO team.

Lead IT category procurement strategy for hardware, software, cloud, and telecom. Negotiate contracts, manage vendor performance, drive cost savings, perform market and spend analytics, mitigate supply chain and cybersecurity risk, and partner cross-functionally to implement preferred supplier programs and continuous improvement.

The Lead IT Telecom Architect designs and optimizes Telecom and Contact Center architecture to meet business goals, ensuring security and performance. Responsibilities include strategy development, technology evaluation, system implementation oversight, and stakeholder collaboration.

Lead design, implementation, and administration of enterprise IT infrastructure with a strong focus on identity and access management across GCP, AWS, and GitHub. Build Okta-driven provisioning workflows, automate processes, manage IAM governance and compliance, support IT support escalations, and evolve security policies including PAM and EDR controls.

Lead and operate Vynca's IT function for a fully remote, HIPAA-regulated healthcare organization. Manage a distributed IT team, own day-to-day operations (hardware lifecycle, provisioning, identity and access), enforce security and compliance (HIPAA, SOC 2), administer MDM/SSO/endpoint tools, support audits, and drive operational improvements while mentoring staff.

The Senior Technology Specialist oversees the design and support of technology solutions, ensuring they meet business needs and compliance standards, while mentoring junior staff and optimizing operations.

Lead technical program manager responsible for planning and delivering corporate IT projects including IAM, M&A integrations, infrastructure and networking upgrades. Own project lifecycle, stakeholder communication, risk and vendor management, IT project intake/process definition, documentation, and budget oversight.

The Business Development Manager will focus on acquiring new clients and expanding accounts within the IT staffing sector, managing the full sales cycle and meeting revenue targets.

Lead design, implementation, and optimization of ServiceNow ITOM (Discovery, Service Mapping, Event Management) and CMDB governance. Configure MID Servers, patterns, probes, and integrations; manage cloud discovery across AWS/Azure/GCP; build automations with Flow Designer and APIs; perform performance and root-cause analysis; liaise with vendors; produce technical strategy, capacity planning, and translate technical solutions for business stakeholders.

Remote IT Manager responsible for analyzing, upgrading, and administering IT systems (networks, servers, email, backups), evaluating vendors and technologies, managing projects, tracking inventory, training staff, and providing technical support to improve operational efficiency.

Lead strategy and execution of IT Computer System Validation and QA for GxP-regulated IT systems. Develop CSV strategy, SOPs, risk management, change control, and training. Oversee validation, vendor qualification, audits/inspections, and compliance of ERP and lab systems throughout the system lifecycle.

The Enterprise Architect leads architectural strategy and integration for technology and processes while aligning IT investments with business goals. Responsibilities include overseeing cloud modernization, governance, and communication with stakeholders.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

The Senior IT Systems Administrator oversees the administration, security, and optimization of financial systems, ensuring reliability and compliance while leading system enhancements and integrations.