Top Senior Python Jobs in Columbus, OH

2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead hands-on development and mentor engineers to build secure, reliable data pipelines, APIs, and reporting for asset management. Own end-to-end delivery, participate in Agile ceremonies, drive automation, AI-assisted engineering practices, and improve operational stability.
Top Skills: Ai-Assisted Development ToolsAWSCi/CdData ModelingDatabricksJavaPysparkPythonRest ApiSnowflakeSpring BootSQL
2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead development of distributed, cloud-native trading and portfolio systems using Java, Python, Spring Boot, Microservices and React. Drive secure, resilient CI/CD automation, AI-assisted engineering governance, code quality, and operational stability while mentoring and managing developers and evaluating vendor/architecture fit.
Top Skills: Ai-Assisted Development ToolsAutomationCi/CdCloud NativeContinuous DeliveryJavaMicroservicesPythonReactSdlc/Tlm ToolchainSpring Boot
2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead design, build, and maintain automation-enabled software using Python and React. Own production outcomes, drive engineering standards, implement Ansible automation on RHEL, troubleshoot networking issues, adopt AI-assisted engineering practices, support customers/incidents, and collaborate with product, security, and operations teams to improve reliability and reduce toil.
Top Skills: Ansible Automation PlatformDnsPythonReactRed Hat Enterprise Linux (Rhel)TcpTls
2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead design and delivery of scalable, secure AWS-based platform solutions. Develop and maintain production code and automation, champion AI-assisted engineering practices, produce architecture documentation, analyze large datasets for resiliency and performance, implement CI/CD and observability, and mentor junior engineers.
Top Skills: Ai-Assisted Development ToolsAppdynamicsAWSAws S3CloudwatchData LakesDatadogDynatraceEc2EcsEksElasticsearchEmrEvent BusGrafanaJavaJenkinsNoSQLPythonSpinnakerSplunkSQL
2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead development of secure, production-grade storage/platform software. Design and deliver distributed systems using Python and modern cloud-native practices, drive automation and AI-assisted engineering adoption, troubleshoot complex incidents, mentor engineers, and partner across product, operations, and security to improve reliability and delivery.
Top Skills: Ai-Assisted Development ToolsAWSCi/CdCockroachdbContainerizationContainersDistributed Sql/NosqlDjangoEvent-Driven ArchitectureFastapiInfrastructure-As-CodeJavaObservabilityPythonRabbitMQRest ApiService MeshSlos/SlisZero Trust
2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead SRE/DevOps engineer responsible for designing and delivering resilient, scalable Branch systems. Collaborates with product, architecture, security, and operations to embed reliability best practices across the SDLC, write and review production Java/Python code, implement IaC on AWS, use observability tooling, drive CI/CD and automation, and lead engineering communities of practice.
Top Skills: AWSCi/CdDatadogDynatraceEnvironment As Code (Eac)GrafanaInfrastructure As Code (Iac)JavaObservabilityPythonSplunkTerraform
2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead back-end engineer delivering cloud-native microservices, building scalable, secure, high-volume data processing systems. Design domain models, implement tests, optimize performance, operate production services, and support incident management across distributed systems.
Top Skills: Cloud TechnologiesDistributed SystemsJavaMessaging FrameworksMicroservicesNoSQLPythonRestful ApisSQL
2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead a cross-functional agile team to design, build, test, and operate scalable, secure full‑stack applications. Implement microservices (Java/Spring Boot or Python), cloud-native architectures, RESTful APIs, and high-volume data processing with SQL/NoSQL. Drive code quality, automation/CI-CD, vendor evaluations, and engineering communities of practice while improving operational stability and observability.
Top Skills: Application ResiliencyAWSAxiosCi/CdCloudCloud NativeCSSCypressDistributed SystemsDynatraceEs6GrafanaHTMLJavaJavaScriptJestJSONMicroservicesNoSQLPythonReactReact Context ApiReact QueryRestful ApisSecuritySplunkSpringSpring BootSQLTypescriptWebpackWebsockets
2 Days AgoSaved
Hybrid
Columbus, OH
Senior level
Senior level
Financial Services
Lead technical design and development of secure, scalable production software. Write and review code, drive automation and CI/CD, ensure operational resilience, promote enterprise AI-assisted engineering practices, evaluate vendor/architecture choices, lead communities of practice, and coach teams on secure, compliant cloud-native solutions in a financial services environment.
Top Skills: Ai-Assisted Development ToolsAutomation/Continuous DeliveryCi/CdCloudCloud-NativeDjangoJavaScriptPythonSQL
Reposted 11 Days AgoSaved
Easy Apply
Remote or Hybrid
Columbus, OH
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
Reposted 16 Days AgoSaved
Remote
Columbus, OH
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Reposted 4 Days AgoSaved
In-Office
Columbus, OH
Senior level
Senior level
Artificial Intelligence • Computer Vision • Machine Learning • Robotics • Business Intelligence • Automation • Manufacturing
Lead the development of core systems for intelligent robotic platforms, design and optimize performance-critical components, and integrate machine learning into real-time systems.
Top Skills: C++DockerGrpcLinuxProtobufPythonRos
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Reposted 21 Days AgoSaved
Remote
Columbus, OH
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 23 Days AgoSaved
Remote
Columbus, OH
Senior level
Senior level
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills: DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Reposted 23 Days AgoSaved
In-Office or Remote
Columbus, OH
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
YesterdaySaved
Remote
Columbus, OH
120K-140K Annually
Senior level
120K-140K Annually
Senior level
Artificial Intelligence • Big Data • Cloud • Information Technology • Machine Learning
Design and build full-stack applications that expose AI/ML insights. Develop backend services in Python, RESTful APIs, and containerized microservices. Build high-performance front-end interfaces with React/Vue/Angular. Implement cloud-native solutions on Google Cloud or Azure, manage relational and NoSQL databases, apply testing and CI/CD, and participate in Agile development and architecture sessions.
Top Skills: AngularAzureCi/CdDockerGCPJavaScriptKubernetesMongoDBMySQLPostgresPythonReactRestful ApisSQL ServerTypescriptVue
Reposted 3 Days AgoSaved
Remote or Hybrid
Columbus, OH
Senior level
Senior level
Digital Media • Social Media • Software • Design
Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.
Top Skills: Python
Reposted 3 Days AgoSaved
In-Office or Remote
Columbus, OH
Senior level
Senior level
Agency • Information Technology
Design, build, test, and maintain backend applications using FastAPI and SQLAlchemy. Implement database schemas, integrate front-end components, optimize for performance and scalability, debug issues, participate in code reviews, and collaborate on feature design. Maintain clean, testable code and stay current with best practices.
Top Skills: FastapiGitMySQLOraclePytestPythonSQLSqlalchemy
Reposted 6 Days AgoSaved
Remote
Columbus, OH
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
Reposted 6 Days AgoSaved
Remote
Columbus, OH
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
Reposted 9 Days AgoSaved
Remote
Columbus, OH
100K-200K Annually
Senior level
100K-200K Annually
Senior level
Artificial Intelligence • HR Tech • Information Technology • Software
As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.
Top Skills: AWSCeleryFastapiOpensearchPostgresPythonRedisTemporal
Reposted 11 Days AgoSaved
Remote
Columbus, OH
125K-200K Annually
Senior level
125K-200K Annually
Senior level
Software • Cybersecurity
The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.
Top Skills: Automation ScriptsCi/CdDevOpsPythonSastWebhook Implementations
Reposted 11 Days AgoSaved
Remote
Columbus, OH
Senior level
Senior level
Artificial Intelligence • Logistics • Software • Transportation
Design, develop, deploy, monitor, and support APIs and system integrations (Salesforce, REST, third-party). Work directly with clients to gather requirements, troubleshoot and optimize integrations, operate solutions in AWS, collaborate with teams, and mentor junior developers.
Top Skills: Aws Api GatewayAws EcsAws LambdaAws RdsPythonRest ApiSalesforceSnsSqsTerraform
Reposted 11 Days AgoSaved
Remote
Columbus, OH
Senior level
Senior level
Information Technology • Logistics • Transportation • Consulting
Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.
Top Skills: .NetC#Ci/CdDevOpsDockerElectronFastapiGraphQLJavaJavaScriptLlmsLookmlMlMongoDBMySQLNode.jsPythonReact NativeReactRestSpringTypescriptVue
Reposted 14 Days AgoSaved
Remote
Columbus, OH
Senior level
Senior level
Automotive
The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.
Top Skills: AirflowAWSElasticsearchKubernetesOcrOpensearchPythonScrapySpark
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