Top Senior Software Engineer Jobs in Charleston, SC

Reposted YesterdaySaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Software • Analytics • Financial Services
Lead development of AI-powered full-stack applications, mentor engineers, define technical direction, build performant front-end and scalable backend services, integrate LLMs/RAG, and establish engineering best practices for production AI workflows.
Top Skills: AWSAzureGCPLlmsNode.jsPythonRagReactTypescript
Reposted YesterdaySaved
Remote
Charleston, SC
157K-199K Annually
Senior level
157K-199K Annually
Senior level
Artificial Intelligence • Big Data • Information Technology • Professional Services • Software
As a Senior Software Engineer, you'll build and maintain high-performance, fault-tolerant infrastructure for GraphQL runtime, mentoring teammates and engaging with users to enhance the platform.
Top Skills: GraphQLRust
Reposted YesterdaySaved
Remote
Charleston, SC
130K-190K Annually
Senior level
130K-190K Annually
Senior level
Other
The Senior Software Engineer is responsible for developing, testing, and maintaining SkySlope software. This role requires collaboration, innovation, and continuous learning with a focus on quality and delivery of software projects.
Top Skills: .Net ClrAngularAuroraAWSC#CodepipelineDynamoDBGitGoJavaScriptJenkinsLoopbackMongoDBMs Sql ServerMySQLNode.jsPostgresReactSvnTfsVue
Reposted YesterdaySaved
Remote
Charleston, SC
160K-190K Annually
Senior level
160K-190K Annually
Senior level
Legal Tech • Software
The Senior Software Development Engineer will develop applications using modern programming languages, provide leadership and mentoring, ensure software quality, and lead software improvement initiatives.
Top Skills: .NetAWSC#Ms SqlOpensearchRedisTypescript
Reposted YesterdaySaved
Remote
Charleston, SC
Senior level
Senior level
Big Data • Healthtech
As a Senior Software Engineer, you will lead full stack projects, design scalable systems, mentor engineers, and ensure high-quality code delivery while driving team alignment and managing processes.
Top Skills: AWSContainersFhirHl7ServerlessSpark
Reposted YesterdaySaved
Remote
Charleston, SC
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Software
The staff software engineer will lead technical design, develop AWS microservices and automation solutions, and mentor team members.
Top Skills: Api GatewayAWSAws BedrockAws LambdaCloudwatchEventbridgeIamRest ApisSecrets ManagerSnsSqsWorkato
Reposted 24 Days AgoSaved
Remote
Charleston, SC
180K-230K Annually
Senior level
180K-230K Annually
Senior level
Software • Energy
The Power Systems Software Engineer will develop high-fidelity power flow models, validate them against customer data, and enhance the architecture for solver performance in grid simulations.
Top Skills: AmiGCPGisOpendssPower SystemsPythonScada
2 Days AgoSaved
Remote
Charleston, SC
180K-240K Annually
Senior level
180K-240K Annually
Senior level
Artificial Intelligence • Marketing Tech • Mobile • Software
Lead cloud FinOps initiatives to increase cost transparency and optimize resource utilization across teams. Mentor engineers on cost best practices, implement cost-saving measures, troubleshoot complex infrastructure issues, develop automation workflows, and influence cost-effective architectural decisions with cross-functional partners.
Top Skills: AWSDatadogJavaKubernetesTerraformVantage
2 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Healthtech • Software
Design, develop, and maintain scalable, secure backend services and APIs for a healthcare caregiver platform. Drive cloud-native modernization (microservices, serverless), ensure compliance (HIPAA, OWASP), troubleshoot production issues, optimize performance, mentor junior engineers, and collaborate with product and architecture teams to deliver reliable, high-performing solutions.
Top Skills: AngularAWSC#/.NetCi/CdCursor AiDockerGithub CopilotHipaaIdentity And Access ManagementKubernetesMicroservicesNoSQLObservabilityOwaspPostgresPythonServerlessSQL Server
2 Days AgoSaved
Remote
Charleston, SC
180K-192K Annually
Senior level
180K-192K Annually
Senior level
AdTech • Marketing Tech • Software
Own and build full‑stack, growth-focused product experiences across the funnel (acquisition, activation, retention, monetization). Ship experiments, measure outcomes with analytics, iterate, and establish reusable infrastructure while collaborating with product, design, and data teams. Drive technical execution and lead end-to-end growth initiatives in a remote, product-led SaaS environment.
Top Skills: FigmaLinearLookerMixpanelNotionOmniReactRubyRuby On RailsSlackSQL
Reposted 2 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Healthtech • Professional Services • Software
Lead design and implementation of scalable backend solutions, collaborate on requirements and specs, troubleshoot complex technical issues, conduct and lead code reviews, ensure rigorous automated testing, leverage AI tools to improve workflows, and support high-volume transactional processing.
Top Skills: Ai ToolsAWSAzureClaude CodeDjangoFlaskGCPGraphQLOrmPython
2 Days AgoSaved
Remote
Charleston, SC
160K-185K Annually
Senior level
160K-185K Annually
Senior level
Financial Services
Lead design, develop, and maintain scalable full-stack web applications. Mentor engineers, perform code reviews, troubleshoot production incidents, optimize performance, ensure API-first design, support cloud-native deployments (Kubernetes), and participate in on-call rotations.
Top Skills: AngularAWSC#CachingCloud NativeCSSFlutterHTMLIntegration TestsJavaJavaScriptKubernetesNoSQLOpentelemetryReactRest ApiSQLUi Automation TestsUnit Tests
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2 Days AgoSaved
Remote
Charleston, SC
40-85 Hourly
Senior level
40-85 Hourly
Senior level
Artificial Intelligence • HR Tech • Software • Generative AI
Provide expert software engineering to improve and optimize codebases used for AI training: bug fixes, feature development, refactoring, performance tuning, architecture recommendations, documentation, and cross-functional collaboration to support scalable AI training workflows.
Top Skills: C++GoJavaPython3RustTypescript
2 Days AgoSaved
Remote
Charleston, SC
215K-230K Annually
Senior level
215K-230K Annually
Senior level
Gaming • Mobile • Social Media • Sports
Lead a pod as technical owner of core, scalable production systems: define architecture, improve reliability and processes, lead planning/releases, mentor engineers, and coordinate cross-functional delivery.
Top Skills: GCPMongoDBNode.jsPostgresReactReact Native
2 Days AgoSaved
Remote
Charleston, SC
175K-190K Annually
Senior level
175K-190K Annually
Senior level
Gaming • Mobile • Social Media • Sports
Design, build, and scale backend services and product features with focus on scalability, reliability, and performance. Contribute to system architecture, write maintainable code, improve observability and performance, and partner with Product and Design to deliver features. Drive projects end-to-end, participate in sprint planning, and mentor engineering best practices.
Top Skills: GCPMongoDBNode.jsPostgresReactReact Native
2 Days AgoSaved
Remote
Charleston, SC
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Software • Database
Build and evolve APIs and frontend surfaces for data products. Translate business requirements into scalable systems, ensure data integrity, design frontend and backend architecture, improve developer self-serve tooling, collaborate with stakeholders, and mentor engineers while maintaining strong code quality and delivery practices.
Top Skills: CSSDjangoFastapiFigmaFlaskFrontend Testing FrameworksMySQLNext.JsNode.jsPostgresPythonReactRest ApiRuby On RailsSQLTailwind CssTypescriptUi Component LibraryVercel
2 Days AgoSaved
Remote
Charleston, SC
190K-220K Annually
Senior level
190K-220K Annually
Senior level
Edtech • Software
Lead architecture and implementation of new school-safety products from concept to production. Design scalable, secure, and resilient distributed systems; build third-party and device integrations; collaborate with product and design; mentor engineers; and prioritize operational reliability, privacy, and compliance.
Top Skills: APIsCloud-Native ApplicationsDevice IntegrationsEdge-To-CloudEvent-Driven ArchitecturesIotOauthObservabilitySAMLSsoWebhooks
Reposted 2 Days AgoSaved
Remote
Charleston, SC
144K-200K Annually
Senior level
144K-200K Annually
Senior level
Software
Lead company-wide transformation of test automation and quality engineering: define vision and roadmap, architect scalable testing frameworks across server/web/mobile/desktop, integrate AI/LLM for test generation and flakiness management, establish observability and quality gates, mentor engineers, and partner with leadership to embed quality across the SDLC.
Top Skills: Ai/Llm TechnologiesApi TestingCi/CdCloud-Based Test EnvironmentsCypressDetoxDistributed SystemsDockerGoKubernetesObservabilityPerformance TestingPlaywrightPostgresReactReact NativeSecurity TestingTypescript
Reposted 2 Days AgoSaved
Remote
Charleston, SC
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Fintech • Financial Services
Design, develop, and deliver scalable backend systems and components using .NET 10 and C#. Build and maintain databases and messaging infrastructure (PostgreSQL/SQL Server, RabbitMQ), deploy with Docker and AWS, apply DDD and ORMs, triage/prioritize work, and contribute to distributed, event-driven architecture with emphasis on reliability and idempotency.
Top Skills: .Net 10AWSC#DockerDomain Driven DesignEntity FrameworkMasstransitNhibernateNservicebusPostgresRabbitMQSQL Server
Reposted 2 Days AgoSaved
Remote
Charleston, SC
148K-185K Annually
Senior level
148K-185K Annually
Senior level
Healthtech • Software
As a Senior Full Stack Engineer, you'll enhance pharmacy services, optimize prescription workflows, mentor engineers, and solve technical challenges in healthcare.
Top Skills: PostgresPythonRuby on Rails
Reposted 2 Days AgoSaved
Remote
Charleston, SC
266K-426K Annually
Senior level
266K-426K Annually
Senior level
Software
Lead the architecture of Commerce Hub by defining core domain models, building intricate systems, and mentoring engineers while influencing product strategy.
Top Skills: AICRMDistributed SystemsFinancial Models
Reposted 2 Days AgoSaved
Remote
Charleston, SC
155K-210K Annually
Senior level
155K-210K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Database
As a Senior Software Engineer, you'll optimize distributed databases, focus on query efficiency, and collaborate on SpiceDB features, enhancing performance and reliability.
Top Skills: C/C++Ci/CdDockerGitGoRustZig
Reposted 2 Days AgoSaved
Remote
Charleston, SC
195K-220K Annually
Senior level
195K-220K Annually
Senior level
Healthtech • Software
As a Senior Software Engineer, you will collaborate with teams to build tools enhancing healthcare, drive business outcomes, and adopt AI in development.
Top Skills: AIFull-Stack EngineeringVarious DatabasesWeb Frontend Technology
Reposted 2 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Security • Software
Lead the development of a search and data integration platform, ensuring architecture, integration, and delivery of complex software systems in a safety-focused environment.
Top Skills: Amazon SnsAmazon SqsApi GatewayAuroraAWSCloudwatchDynamoDBEcsEksIamJavaKinesisLambdaRdsReactS3Step FunctionsTypescript
Reposted 2 Days AgoSaved
Remote
Charleston, SC
180K-210K Annually
Senior level
180K-210K Annually
Senior level
Artificial Intelligence • Marketing Tech • Mobile • Software
As a Senior Software Engineer on the Identity team, you will enhance systems that process billions of events, ensuring performance and stability. Collaborate with teams to design algorithms for user identity, manage data quality, and improve capture accuracy.
Top Skills: Data Processing SystemsSoftware Development
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