Top IT Support & Helpdesk Jobs in St. Louis, MO

Support IT department projects and applications: assist with MS Project scheduling, track metrics, create documentation, ensure standards compliance, participate in QA and application testing, and update production plan targets.

Provide L1/L2 endpoint and enterprise app support while building AI-driven self-service, automations, and knowledge articles to reduce ticket volume. Troubleshoot hardware, software, and network issues, assist onboarding/offboarding, analyze ticket trends, and collaborate on problem resolution and AI tool evaluation.

Provide hands-on help desk support: image and install OS/software, deploy and connect equipment, tag and inventory hardware, unpack and validate components, troubleshoot hardware/software issues, and assist the Technology Services team with administrative tasks.

Maintain and support mission-critical enterprise application infrastructure: install, configure, patch, and upgrade Windows and Linux servers; monitor performance; troubleshoot hardware/software/OS issues; deploy across environments; automate with PowerShell/Bash/Python; perform backups and disaster recovery; ensure RMF/STIG compliance; manage AD and permissions; support incident response and accreditation; participate in on-call rotation and liaise with customer.

Serves as the EDI specialist within the ERP Administration team, configuring, testing, monitoring, troubleshooting, and maintaining EDI maps, trading partnerships, transformations, workflows, and integrations. Supports Cleo Integration Cloud and IFS Cloud ERP, onboards trading partners, translates implementation guides, manages ANSI X12 and EDIFACT documentation, and resolves transmission and data validation issues. Collaborates with business and IT teams and provides occasional after-hours support.

Deliver and deploy IT infrastructure for new offices and moves, designing networks and unified communications, ordering and installing telecom circuits and equipment, performing server administration and patching, supporting end user computing (Windows/Mac), administering data center installs, providing training, documentation, on-call support, and occasional domestic/international travel.

Supports policy administration systems and related business applications by assisting with technical support, executing User Acceptance Testing, documenting processes, maintaining knowledge resources, and tracking system issues. Acts as a liaison between business users and Information Technology, contributes to continuous improvement, and manages multiple priorities while delivering professional customer service. The hybrid role requires at least three days weekly in the St. Louis corporate office.

Provide Netezza database administration and support: create users/groups and permissions, configure users, troubleshoot query and system performance, analyze log and plan files, manage backup/restore concepts, run gen-stats/reclaim/groom/nz_migrate, handle DB errors, implement hardware events, deploy changes from dev to prod, liaise with IBM Netezza support and application teams, and provide 24/7 global support.

Provide technical support, onboarding, lifecycle management, upgrades, integrations, migrations, and incident resolution for clinical applications and supporting infrastructure. Collaborate with clinical stakeholders, vendors, and IT teams to ensure reliable, secure, and compliant systems, assist with requirements, testing, documentation, and continuous improvement across clinical technology platforms.

Manage and optimize on-premise Windows/Linux server infrastructure and virtualization. Administer AD, DNS, DHCP, Group Policy, perform patching, backups, endpoint management, Tier 2/3 support, documentation, and vulnerability remediation. Participate in on-call rotations and after-hours maintenance while coordinating with security teams.