Top Remote Software Engineer Jobs in St. Louis, MO

As a Distributed Systems Engineer, you'll design and evolve LiveKit's core systems, implement resilient architectures, and enhance reliability and developer velocity, working on critical features in production environments.

Design and evolve core control, data, and observability systems; implement resilient region-spanning architectures; build libraries, protocols, and tooling; diagnose and harden critical paths using metrics, tracing, and testing; and shape platform capabilities across identity, scheduling, observability, and distributed state management.

The role involves designing and evolving core systems at LiveKit, implementing resilient architectures, and building tools to enhance system reliability and developer speed. Strong distributed systems experience and programming skills are essential.

Design, implement, and operate low-latency, highly available distributed control, data, and observability systems. Build region-spanning architectures, libraries, protocols, and tooling; diagnose and harden critical paths using metrics, tracing, testing, and real traffic; and shape platform capabilities around identity, scheduling, observability, and distributed state management.

Lead architecture and development for scalable document content extraction and transformation systems. Build full-stack, event-driven applications using C#/.NET, AWS, Kafka, OCR technologies, APIs, and AI services. Own initiatives from design through production, improve reliability and performance, implement observability, address technical debt, document architecture, collaborate cross-functionally, and mentor engineers.

Design, develop, and optimize high-performance confidential computing solutions using CUDA. Identify and resolve performance bottlenecks through advanced CUDA programming and profiling tools. Write clean, tested, documented code and collaborate with developer services and infrastructure teams to integrate GPU-accelerated algorithms into existing systems. The role also involves building cryptographic and distributed systems supporting privacy-preserving zero-knowledge products.

Own backend and AI infrastructure for autonomous trading agents. Build the Go-based agent runtime, execution and data layers, real-time trading systems, deployment platform, model hosting migration, telemetry, CI/CD, monitoring, and incident response. Develop production services primarily in Go, Python, and TypeScript while operating AWS EKS infrastructure. The role requires end-to-end ownership of reliable, low-latency systems managing real-time trading and financially sensitive positions.

Build and own Pepper’s regulated audit platform across internal auditor tools, client and partner portals, data models, integrations, security, and reliability. Develop end-to-end features using TypeScript, React, Node.js, PostgreSQL, and Supabase. Design secure multi-tenant data isolation, authentication, audit logging, evidence integrity, integrations, observability, CI/CD, and deployment workflows. Partner with founders, auditors, CPAs, engineers, and external partners in a high-autonomy environment.

As a Senior Software Engineer (Backend), you will design and implement scalable applications, collaborate with agile teams, and mentor junior members while ensuring high code quality and performance.

The Staff Software Engineer will lead technical vision and execution, drive architectural decisions, mentor engineers, and ensure code quality and scalability.

Build and operate full-stack, production-ready systems: design and ship AI-native mortgage automation, integrate third-party lending APIs, and architect scalable AWS infrastructure and job processing. Mentor engineers and ensure security, observability, and high reliability.

The Staff Software Engineer will lead technical projects, develop full-stack software, mentor teams, and drive product direction at Propel, focusing on impactful solutions.

Design, build, and maintain CRM+ features using C#, .NET, Vue, and SQL Server on Azure. Architect scalable services, use AI tools (Claude Code) in development, write well-tested code, mentor engineers, influence product and technical strategy, operate CI/CD, troubleshoot production issues, and collaborate cross-functionally.

Develop user interface components for ArcGIS Pro using C# and WPF, work in an agile team, and design software solutions for raster and imagery processing.

Lead full lifecycle development of high-volume enterprise web applications using C#/.NET and AngularJS. Contribute to architecture and design, develop and test scalable solutions, troubleshoot production issues, mentor developers, and collaborate with analysts and business stakeholders in an Agile/Scrum environment.

The Senior Software Engineer will enhance patient experiences by developing modern software for doctor's offices, contributing to product features, and participating in client feedback.

The Staff Software Engineer will upgrade patient experience by developing features for a healthcare software platform, leading the product development throughout the process.

As a Senior Software Engineer, you will develop efficient systems to enhance healthcare delivery and collaborate with various teams to innovate features for patient care tools.

Design and build core systems for a new application using Solana's infrastructure. Focus on low-latency, reliable services, and implement security measures.

The role involves developing and maintaining integrations for workforce software, collaborating with HR and IT, and providing technical support.

Join Vanta as a Senior Software Engineer to lead and mentor teams, driving projects on identity systems and improving security infrastructure.

Lead architecture and build scalable, secure production services while championing AI-native development. Mentor engineers, influence technical direction, review PRs, and help evolve a legacy monolith to a modern stack in partnership with product and exec leadership.

Design, build, and maintain backend systems for metrics and monitoring, collaborate across teams, and debug production incidents.

As a Senior Software Engineer, you'll design and implement full-stack features, develop AI-driven workflows, and ensure code quality for a dental billing platform while collaborating with users to address their needs.

Design and develop web applications, mentor teammates, shape architectural decisions, write clean code, conduct testing, and troubleshoot issues.