Top Remote Data Science Jobs in St. Louis, MO

As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.

As a Data Scientist, you will build predictive models, develop software tools, and analyze geoscientific data to support mineral exploration and discovery.

The Data Scientist will develop predictive models, analyze geophysical data, and collaborate with geoscientists to enhance exploration programs, focusing on mineral deposits.

As a Data Scientist, you will develop predictive models, analyze geoscientific data, and collaborate with geoscientists to improve mineral exploration efforts.

Design, build, and deploy production-grade machine learning models and analytical solutions. Work end-to-end from problem definition to production, write performant Python and SQL, resolve data quality issues, collaborate with product and engineering, support on-call, automate reporting, mentor junior teammates, and improve model reliability and workflows.

Develop autonomous AI agents capable of goal setting, decomposition, planning, tool use, memory, and long-horizon execution. Build evaluation frameworks for alignment, reliability, and safety; identify goal misalignment and undesirable behaviors; and integrate agent systems with APIs, databases, search engines, and other tools. Responsibilities include designing production-ready machine learning systems, collaborating across teams, and advancing agent autonomy through planning, causal reasoning, model-based reinforcement learning, and language modeling.

Owns the end-to-end development of cybersecurity vulnerability and exploit prediction models, including problem framing, feature engineering, training, evaluation, deployment, calibration, monitoring, and drift detection. The role addresses extreme class imbalance, hierarchical modeling, cold-start customers, and uncertainty quantification. It also requires explaining model outputs to security executives, publishing methodologies and benchmarks, and partnering with engineering to deploy reliable production systems.

Provides biostatistical data science and analytics support for clinical development and evidence generation. Collaborates with biostatistics, data management, clinical development, and medical affairs teams; applies statistics, mathematics, AI, and innovative technologies to clinical trial and real-world data. Contributes to clinical trial design, statistical analysis plans, clinical study reports, publications, and protocol development while following ICH and FDA guidelines.

Own end-to-end data science for a priority vertical (starting with Insurance): frame business problems, build and validate models, partner with ML engineering for deployment, monitor live ROAS performance, and drive measurable revenue and lead quality improvements.

Lead end-to-end data science projects including predictive modeling, algorithm design, and data pipelines. Build campaign-focused models (turnout, partisanship), perform exploration and visualization, translate insights into memos/presentations, collaborate with engineering to productionize models, mentor junior data scientists, and prototype emerging AI solutions for product impact.

The Senior Data Scientist will lead innovative data science efforts, leveraging advanced analytics, visualization, and insights from complex datasets to boost productivity.

Lead predictive modeling and causal inference initiatives for clients, developing models from exploratory analysis through production deployment, monitoring, and retraining. Apply GLMs, econometric methods, uplift modeling, propensity methods, and deep-learning forecasting. Process large-scale data with SQL and Spark, build models in Python, improve production reliability, and communicate findings to technical and business stakeholders in a consulting environment.

Build marketing data science models and decision systems for spend allocation, channel measurement, forecasting, experimentation, and growth optimization. Unify marketing, retail, revenue, and product data; develop dashboards and analytical products; apply AI/ML and causal inference; and translate complex analysis into actionable recommendations for executives and cross-functional teams. The role also includes improving data quality, mentoring, documentation, and technical leadership.

Lead data science work embedded in the newsroom: identify high-impact problems, build and productionize predictive and explanatory models, own core metrics/measurement, apply causal inference and experimentation, translate findings for senior stakeholders, and mentor junior data team members to improve analytic standards and adoption.

Lead end-to-end data science initiatives for commercial property or homeowners insurance: acquire and prepare data, build and validate predictive models, deploy and monitor production models, ensure governance and documentation, advise teams, and evaluate emerging ML/AI techniques to improve pricing, risk selection, and underwriting outcomes.

Design and implement advanced ML models for real-time forecasting and decision support, ensure data provenance and lineage, integrate federated geospatial and multi-format data, produce ROM and quarterly cost/resource reports, and apply Agile sprint practices to deliver mission-aligned analytics for DoD/IC customers.

As a Senior Data Scientist at Yahoo Mail, you will enhance user growth strategies via product innovation, overseeing research projects and analytics.

Develop and validate SDTM and ADaM datasets using R per CDISC standards, support TLF generation in R or SAS, perform QC and reconcile data issues, collaborate with biostatistics and clinical teams, and contribute to automation and reproducible workflows for regulatory submissions.

Build, ship, and own end-to-end ML models for vendor matching, order routing, and supply-chain optimization. Partner with data engineering to productionize models, quantify impact, document work, and implement decision logic components toward agentic AI in a fast-moving healthcare startup environment.

Lead development of time-series and econometric models (ARIMA, VAR, state-space, WLS, panel data) and Bayesian probabilistic frameworks. Use causal inference and stochastic processes to produce actionable insights, work with large datasets on Databricks, communicate results to stakeholders, and mentor junior team members.

Lead advanced analytics and ML projects: perform EDA, feature engineering, statistical modeling, and build/optimize production ML and Generative AI solutions (LLMs, embeddings, RAG). Collaborate with engineering and MLOps to deploy and monitor models, create visualizations and dashboards, translate insights for stakeholders, and mentor junior team members.

Design, build, and deploy production generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector databases, integrate/benchmark LLMs, fine-tune models, and deploy scalable FastAPI-based services with monitoring, CI/CD, and Dockerized production pipelines.

Design, build, and deploy production-grade generative AI systems: multi-agent orchestration, advanced RAG with vector databases, integrate/swap LLMs, fine-tune models, optimize prompts and latency, and containerize services with monitoring and CI/CD.

Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.

Design, build, and scale production Generative AI systems: multi-agent orchestration, advanced RAG with vector databases, LLM integration and fine-tuning, scalable FastAPI backends, Dockerized deployment, monitoring, and GenAI optimization for latency, cost, and reliability.