Top Remote Python Jobs in Houston, TX

The Senior Software Developer will design and develop web and mobile applications, collaborate with scientists, implement APIs, and mentor developers.

Develop and maintain the Keycard Agent SDK, ensuring compatibility with various languages and frameworks, while engaging with the developer community to enhance agent applications.

As a Senior Software Engineer, you will lead your team in delivering features according to specifications, ensuring scalable technical decisions, and mentoring team members.

Develop, test, deploy, and maintain UiPath RPA solutions focused on identity and access processes. Integrate bots with APIs, databases, and third-party systems; document workflows and designs; monitor and support production bots (including after-hours/24/7 support); collaborate with business units and follow agile/Scrum practices while ensuring security and compliance.

Serve as engineering lead for Fool.com and Motley Fool Money: set technical direction, write and review code, mentor engineers, own production reliability (incident response, observability), integrate AI/LLM features, and collaborate with cross-functional partners to align technical strategy with business goals.

Lead and develop a remote team of Python engineers, ensuring their growth and satisfaction while driving high-quality software delivery.

The Blockchain Site Reliability Engineer is responsible for maintaining blockchain nodes' reliability, monitoring, incident response, and building automation tools to enhance operations.

Design and implement AI-powered educational software, focusing on generative AI systems, mentor peers, and ensure scalable, secure architecture.

The role involves designing data ingestion and processing systems, writing scalable backend applications, and optimizing performance of business-critical endpoints.

As a Senior DevOps Engineer at Scribe, you will design and optimize AWS cloud infrastructure, manage CI/CD pipelines, and support product development while ensuring reliability and performance of services.

Lead full-stack development across backend and frontend systems, implement and maintain features, fix bugs, collaborate with product and design, support client projects, and contribute to a distributed remote engineering team focused on high-impact startup missions.

Lead architecture and delivery of AI-native contact center solutions using Amazon Connect and generative AI. Design AI agents, contact flows, serverless backends, analytics lakes, IaC, CI/CD, observability, and migration plans. Mentor engineers, drive technical decisions, manage risk, and support pre-sales and customer enablement.

Build and deliver AI-assisted QA curriculum as part-time instructors, authors, or subject-matter experts. Create and review course content, lead workshops, design exercises, advise on AI QA workflows, and support curriculum improvement with hands-on tool experience.

Design, build, and operate production-grade OpenStack platforms including compute (Nova), networking (Neutron), and Ceph storage. Implement HA, capacity planning, virtualization tuning, SDN integrations, automation (Ansible/Terraform), Kubernetes-based control planes, bare-metal provisioning (Ironic), observability, upgrades, and on-call/night-shift support.

Support and improve production SaaS infrastructure across AWS, colocation, and hosted platforms. Administer Windows and Linux systems, virtualization, storage, networking, and database support. Lead incident troubleshooting, root cause analysis, monitoring improvements, vulnerability remediation, automation initiatives, and medium-sized infrastructure projects. Collaborate on compliance (SOX/PCI/HIPAA), disaster recovery, and documentation to increase operational reliability.

The Software Engineer in Platform Operations designs and manages core infrastructure, ensuring secure, scalable, and reliable platform operations while collaborating with software engineers to improve deployment experiences.

Customer-facing senior Solutions Architect leading and mentoring engineers to design and deliver cloud-native, secure CI/CD solutions. Own POCs and packaging (Zarf/UDS), build CI/CD pipelines, deploy and troubleshoot containers and Helm/Kustomize artifacts across AWS/GCP/Azure, and drive process improvements and enablement for Defense customers.

Lead full-stack engineering for a B2B partner portal: design and deploy React/TypeScript front ends, .NET services, and Python data pipelines (Databricks). Integrate LLMs and agentic development into product and workflows, mentor engineers, ensure quality engineering practices, and resolve production issues end-to-end.

Provide mid/senior-level application DBA support for MySQL and PostgreSQL: participate in Agile teams, design data models, maintain DB environments, implement HA/DR and replication, optimize performance, lead production incident response, manage backups/patching/changes, and mentor junior DBAs.

Lead reliability, observability, and resilience for cloud-based financial SaaS. Define SLOs/SLIs, design monitoring/tracing, own incident response and runbooks, build IaC and automation, implement AIOps, perform chaos and load testing, and write production-grade Python tooling while ensuring security and compliance.

Design, build, and lead AWS-based contact center solutions (Amazon Connect, Salesforce Service Cloud Voice). Develop integrations, implement CloudFormation/Lambda, apply IaC and CI/CD, perform code reviews, provide technical advisory, documentation and training, and ensure secure, scalable architectures.

Embed with U.S. government and military customers to deploy, integrate, debug, and maintain C2 software in austere operational environments. Build integrations, troubleshoot distributed systems, contribute to core services, support on-call and nonstandard hours, and travel extensively to ensure mission reliability and deliver field-driven product improvements.

Build end-to-end production features across backend, frontend, and database. Integrate LLM APIs and agentic workflows into products and internal developer tools. Improve CI/CD, deployment, and developer infrastructure. Debug production issues on GCP and containerized services; participate in code reviews and architecture discussions on a small collaborative team.

Configure and implement Alkami digital banking products and third-party integrations, troubleshoot technical issues, perform testing and validation, document configurations, coordinate with project managers and vendors, and support clients through implementation and post-go-live stabilization.

The RF Modeling Manager will architect AI-driven models for indoor localization, improve RF propagation models, and deploy real-time scoring pipelines. Responsibilities include mentoring, collaborating across teams, and ensuring model reliability and accuracy.