Top Remote Python Jobs in Houston, TX

Lead design and build of production-ready cloud and AI systems, prioritize security and reliability, ship solutions quickly using modern engineering practices, collaborate with cross-functional teams, mentor engineers, drive customer adoption, and deliver reusable assets and end-to-end complex deliveries.

Support deployments and post-sale operations of Copia's DeviceLink and Source Control in industrial OT environments. Provide technical support, lead pilots, enable customers, advise on OT network security, collaborate with sales and engineering, and travel up to 25% for on-site assistance.

Twelve-week virtual fellowship teaching Palantir Foundry and AIP through live sessions and projects. Expect 5–10 hours/week, hands-on training, mentorship, certification opportunity, and potential interviews for employment. Program is unpaid.

Design and implement cloud-based solutions with customers; write and reuse code, produce design documents, decompose and estimate work, act as on-call DRI to monitor and restore services, collaborate with cross-functional teams, contribute to open-source, and stay current with engineering best practices.

Own architecture and delivery of core ledger and transaction processing systems. Design and build highly available, high-performance backend services, drive cross-team technical initiatives, establish platform standards, mentor engineers, and embed AI to improve operations and workflows.

Lead SRE efforts for DFIN SaaS: ensure availability, performance, scalability, and automation. Implement monitoring, CI/CD, IaC, container orchestration, AI-enhanced observability, incident response, RCA, and runbook automation while collaborating across engineering teams.

Responsible for leading a team of engineers, supporting product development, identifying technical issues, and ensuring high-quality code delivery in backend systems at scale.

Develop a platform for liquidity and loan collateralization. Responsibilities include building and integrating data pipelines, creating user experiences, and collaborating with teams for system design.

Develop ML/RL models and infrastructure for AV simulations, optimize training loops, and support project timelines in autonomous vehicle tech.

Lead technical strategy and delivery for backend marketplace/search systems. Collaborate with PM, design, and analytics; own operational reliability, monitoring, on-call, testing, and runbooks; set code/design standards; drive major feature delivery and deprecations; mentor and develop engineering talent.

Design, build, and maintain People systems automations and integrations (Workato, Workday, Greenhouse, Slack) using production-quality code. Improve CI/CD, reliability, observability, and AI-driven automation (Claude, MCP). Serve as technical lead for People Technology, partner with stakeholders, and drive scalable, maintainable automation solutions.

As a Senior Software Engineer, you'll support projects from conception to completion, build and extend React applications, and contribute to Vetcove's platform development.

Design, build, and maintain high-throughput data ingestion and processing pipelines; integrate AI-powered infrastructure; implement and support complex computing algorithms and distributed services; own systems end-to-end including architecture, observability, reliability, and operational support; lead architectural initiatives and reduce system complexity while maintaining performance on large-scale real-time data.

Designs, builds, and maintains cloud-based integrations and data workflows using Python and Azure. Develops Azure Functions, internal SDKs for Brightree, Snowflake pipelines, and CI/CD. Uses AI tools to accelerate development, supports automation with Power Automate, troubleshoots production, and documents APIs and workflows.

Lead development of guidance, navigation, and control (GNC) systems from concept to flight-ready software. Design and simulate algorithms, translate requirements into embedded implementations, support HIL and flight test, analyze test data, coordinate across vehicle design, avionics, structures and testing, and document results while mitigating technical risk.

Design, build, and own backend services for prediction markets across market lifecycle: creation, trading, oracle resolution, settlement, and payouts. Build low-latency, high-throughput microservices and event-driven systems, drive reliability via SLOs and observability, lead incident response, set technical standards, and mentor engineers while partnering cross-functionally to deliver product and compliance-aligned roadmaps.

Lead architecture and delivery of large-scale React and React Native frontends. Define frontend strategy and best practices, build shared component libraries and design systems, optimize performance and accessibility, collaborate with product/design/backend teams, mentor junior engineers, and resolve complex frontend and cross-stack issues.

Design, build, and maintain scalable AWS and Azure infrastructure using Infrastructure-as-Code. Develop automation, deployment pipelines, and production release processes. Contribute code to cloud services, manage networking and IAM, ensure availability and security, and respond to incidents while collaborating on observability and security practices.

Design, implement, and optimize high-performance backend systems in Rust for an xOT security platform. Participate across the development lifecycle—debugging, testing, and performance tuning—while integrating relational and NoSQL data stores, microservices, third-party devices, and AI tools. Provide technical leadership, code review feedback, and promote secure, reliable, observable distributed systems.

The software engineer will build full-stack features for Kora's voice AI agent, integrating data, refining prompts, and expanding multi-modal capabilities while mentoring peers and ensuring technical quality.

Lead a Reliability Platform Engineering team to build operational intelligence, observability, and AI-driven tooling that improves production availability, resiliency, and operational governance. Partner with Platform, SRE, Infrastructure, and Product teams to define reliability standards, prioritize investments, and deliver scalable reliability and automation solutions.

Design and implement CIAM backend services for authentication and authorization. Integrate identity systems, manage secure flows, and automate infrastructure.

Lead technical strategy and execution for a backend ledger team building highly available, audit-grade financial systems. Drive architecture, reliability, monitoring, on-call practices, code quality, cross-functional collaboration, and mentoring to ensure accurate, scalable ledger operations.

Build and maintain end-to-end product features across frontend, backend, and databases. Design APIs, authentication, data models, integrations, and AI-assisted workflows. Ship production-ready SaaS components, debug across the stack, improve reliability and performance, and collaborate on product and architecture decisions in an early-stage startup.

Support flight software certification for the Nyx orbital vehicle through V&V and IV&V, requirements management and tracing, test planning, documentation for certification and NASA safety reviews, standards interpretation, interfacing with system engineering and product assurance, and contributing to software design and integrated mission testing using C++ and Python.