Top Remote Software Engineer Jobs in Charleston, SC

The Principal Software Engineer will lead architectural direction, integrate AI capabilities, mentor engineers, and tackle complex technical challenges for scalable systems.

The role involves leading a team to design, develop, and implement AI-driven applications on the ServiceNow platform while managing all aspects of application development and integration with other systems.

Lead the architecture of Commerce Hub by defining core domain models, building intricate systems, and mentoring engineers while influencing product strategy.

Lead design and implementation of scalable .NET Core + Angular applications. Communicate with stakeholders, estimate work, drive agile delivery, ensure code quality, mentor engineers, and collaborate across product, QA, and design to deliver client-facing solutions.

Design, build, and maintain high-scale data ingestion pipelines. Collaborate with product management to define requirements and deploy resources in cloud data providers.

As a Senior Software Engineer, you'll build scalable APIs, manage unstructured data, and develop both open source SDK and enterprise solutions.

As a Senior Software Engineer on the Graph Analytics team, you'll design and implement algorithms for analyzing cryptocurrency transaction networks and collaborate with data scientists and engineers to enhance risk models.

The role involves leading initiatives for managing federal cloud environments, focusing on DevOps best practices, infrastructure reliability, and mentoring junior engineers.

The Senior Software Engineer/DevOps will design and maintain scalable services, develop web applications, manage CI/CD pipelines, provide production support, and mentor junior developers in a high-throughput laboratory environment.

Design and maintain scalable backend services, develop GraphQL APIs, manage data infrastructure, and support operational excellence in a collaborative environment.

The role involves developing and maintaining core infrastructure and services, collaborating with teams, and ensuring high availability and performance.

The Principal Software Engineer will lead software architecture, design, and development for genetic testing systems, collaborating across teams to deliver robust solutions that enhance patient care.

The Senior Software Engineer will lead the design and development of complex systems, mentor team members, and ensure technical excellence while collaborating with various teams to optimize workflows.

As a Senior Software Engineer, you'll optimize distributed databases, focus on query efficiency, and collaborate on SpiceDB features, enhancing performance and reliability.

Lead design and evolution of event-driven, distributed systems; drive cross-team architecture and delivery; mentor engineers; improve reliability, observability, and scalability; influence technical direction and engineering culture.

As a Senior Software Engineer, you will build software for carbon dioxide removal efforts, focusing on full-stack development and optimizing complex workflows.

The Staff Software Engineer will design and implement user-facing features, architect systems, ensure code quality, and integrate modern tools in a fast-paced environment.

Design and build core LLM platform primitives, safety and observability infrastructure, provider abstraction and evaluation systems, prompt lifecycle and Agent-as-a-Service; collaborate with product teams, document reference implementations, and lead technical standards to enable other engineers to build production AI features.

The Staff Software Engineer will develop user experiences and APIs for banking applications, focusing on code quality, system design, and team mentorship.

As a Staff Software Engineer, you will build and iterate AI-enabled products, working on both the front- and backend, collaborating closely with engineers and dental billers.

Develop and maintain scalable, cloud-based platform services. Enhance reliability and observability, automate infrastructure, provide technical leadership, and improve operational excellence across teams.

The Sr Software Development Engineer will design and maintain scalable cloud-based solutions, lead project technical direction, and ensure high-quality deliverables in a fast-paced Agile environment.

As a Senior Software Engineer at Flex, you'll design and maintain financial services architecture, mentor junior engineers, and ensure scalability and security for innovative financial products.

Build and improve application and developer infrastructure for a FedRAMP-high US environment: support US-specific hosting/on-call, enhance auth/RBAC, feature-flag tooling, CI/CD, monitoring, and developer experience while collaborating across engineering teams.

Build AI/ML-powered features across ClickHouse Cloud, designing scalable APIs, integrating inference systems and vector DBs, implementing frontend interfaces, and ensuring production-grade monitoring, versioning, and observability for model deployments.