Top Remote Software Engineer Jobs in Charleston, SC

Design and build scalable frontend and backend features for route planning, routing, navigation, and route execution products. Partner with product, design, and engineering leadership to improve planner efficiency, leverage AI appropriately, and promote technical excellence. Mentor junior engineers, contribute to team growth, engage with customers, and help scale products across industries and customer verticals.

Develop, test, deploy, and support solutions for the ScriptMed Cloud Platform using C#, SQL, and scripting. Configure systems for customer onboarding and tenant creation, automate manual workflows, translate business requirements for distributed engineering teams, and collaborate on designs and troubleshooting. The role requires responsible handling of sensitive data, adherence to HIPAA and security policies, project ownership, documentation, and participation in an after-hours on-call rotation.

Leads full-stack software engineering and technical delivery for enterprise applications across the Microsoft .NET and Azure ecosystem. Designs scalable architectures, APIs, integrations, distributed and event-driven systems, and cloud-native solutions. Provides hands-on development, code reviews, troubleshooting, DevOps collaboration, CI/CD, production support, and operational improvement. Mentors engineers, coordinates technical delivery, manages risks and dependencies, and partners with Product, Architecture, Security, QA, and infrastructure teams.

Develop and integrate complex software applications as part of a Honeywell engineering team. Interns will contribute software features to products, apply software development lifecycle and configuration management practices, analyze problems, develop efficient solutions, and collaborate with global teams while receiving mentorship and hands-on experience.

Software engineering intern supporting the design, development, integration, and enhancement of complex software applications. The role involves contributing to team goals, creating innovative solutions, developing high-quality features, applying software development lifecycle and configuration management practices, and collaborating with engineers. Interns receive mentorship, hands-on experience, relocation benefits, and short-term housing when eligible.

Graduate software engineers will develop open-source and commercial software across the Linux stack, from firmware, kernels, and drivers to desktop applications, containers, clouds, and Kubernetes. Responsibilities include writing resilient, performant code, contributing to product roadmaps, engaging with users and open-source communities, addressing customer issues, and developing secure software. The role is globally remote with twice-yearly international team sprints and emphasizes mentorship, collaboration, and continuous technical growth.

Build and scale a telemedicine platform using React, TypeScript, Python, Flask, and PostgreSQL. Own features through development, deployment, and launch; develop integrations; write tests; conduct design and code reviews; resolve production issues; and collaborate with Product, Design, and Quality teams in a Scrum environment. The role also involves mentoring engineers, improving development processes, and communicating technical decisions to nontechnical stakeholders.

Build and ship production software across the frontend and backend, working closely with founders, customers, and product teams. Develop AI-powered features and systems involving web scraping, unstructured data, PDF parsing, and cloud infrastructure. Translate real-world real estate and financing problems into technical solutions, make high-impact decisions, and own shipped code. The internship may convert to a full-time role.

Build and maintain responsive web experiences, PWAs, and native-feeling mobile apps; design secure APIs and third-party integrations; develop conversational AI bots and support automation; implement ad-tech, segmentation, push notifications, analytics, and A/B testing; and optimize performance, reliability, and uptime. The role requires full-stack development, cloud and DevOps fundamentals, and collaboration in a fast-paced startup.

Leads architecture and technical direction for a high-traffic Next.js and React web platform. Responsibilities include improving Core Web Vitals, technical SEO, rendering, caching, APIs, CMS capabilities, experimentation, analytics, testing, deployment, production reliability, and developer mentorship. The role also architects AI-powered web features, establishes responsible AI standards, and partners with product, marketing, SEO, and engineering teams.

Build and scale Airbnb’s AirChatUI AI prototyping harness and native macOS/iOS applications. Lead architecture and implementation across web prototyping, iOS deployment, AI agent integrations, AirChat tooling, and Kyber platform integration. Develop declarative UI features, collaborate with infrastructure, product, security, and design teams, and establish scalable iOS patterns. Enable designers and product managers to create production-oriented prototypes while maintaining quality, accessibility, performance, availability, and release standards.

Leads technical strategy, architecture, and implementation for scalable clinical research software, data pipelines, and AI systems. Owns product-line architecture, resolves complex distributed-systems challenges, drives reliability, security, observability, and operational excellence, and mentors senior engineers. Builds information extraction and agentic AI applications, data modeling and processing pipelines, evaluation frameworks, and cost-efficient inference orchestration. Partners across Product, QA, Data Science, Architecture, Infrastructure, Cloud, and Support to deliver reliable, maintainable systems.

Develop and maintain semiconductor equipment automation and MES integrations using SECS/GEM, SEMI standards, Ignition, Python, REST APIs, and databases. Design equipment-to-host interfaces, station controllers, finite-state workflows, data collection, tags, and web or desktop applications. Validate MES processes, support SPC software, debug and host applications, and work with hardware and semiconductor manufacturing systems. The role also requires strong analytical, communication, leadership, project management, and application ownership skills.

Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.

Lead a small software engineering team supporting intelligence workflows. Build and maintain full-stack web applications, automate workflows, develop agentic AI tools, integrate data across agency elements, and support highside services. Engage directly with customers, leadership, analysts, and developers to understand mission needs, gather feedback, implement solutions, and deliver analytic and workflow support. Responsibilities also include relational database work, pipeline data processing, and cross-domain solution development.

Evaluates AI-generated software code for correctness, quality, architecture, and debugging performance. Creates challenging coding problems, reference solutions, and test cases, then reviews model reasoning and provides detailed technical feedback to improve AI performance on real-world software engineering tasks.

Lead architecture, development, scaling, and reliability for SingleStore Helios, a multi-cloud SaaS platform. Design Kubernetes operators, controllers, networking, routing, and distributed control planes across AWS, Azure, and GCP. Build resilient Go and Python systems, support AI and vector workloads, resolve complex Tier-3 production incidents, and maintain compliance controls. Mentor engineers, author architecture documents, and influence cross-functional technical strategy.

Build and operate reliable, maintainable software for appointment-based businesses. Own product and technical initiatives from design through production, collaborate with Product and Design, contribute to architecture, and develop frontend, backend, or full-stack systems. Ensure quality through testing, code review, observability, and production support while mentoring engineers and improving development practices with AI-assisted tools.

Build and operate high-volume AWS data pipelines and bidirectional CRM integrations for educational fundraising systems. Design idempotent consumers, incremental synchronization, rate limiting, replay, migrations, monitoring, and partner-facing APIs. Collaborate with product, partner, data science, and CRM teams while improving AI-assisted engineering practices. Own major system components or end-to-end architecture, depending on level, and mentor teammates at the higher level.

Build and maintain full-stack donor-facing giving forms, payment flows, recurring giving, memberships, and administrative tools. Own projects from architecture through production support, ensuring reliability, accessibility, performance, and data integrity. Collaborate with product managers, designers, and engineers; mentor junior engineers; contribute to technical standards, security monitoring, hiring, and rotational on-call support. Potentially serve as a Tech Lead for roadmap implementation and technical decision-making.

Build AI platform infrastructure and developer tooling, including API gateways, model routing, integrations, observability, retrieval, caching, and model-serving systems. Develop APIs, microservices, SDKs, and internal tools that connect proprietary real estate data and AI models to production applications. Collaborate with ML engineers, contribute to architecture decisions, and own features through deployment and monitoring.

Lead a portfolio company’s engineering function by writing production code, modernizing the software development lifecycle, coaching engineers, setting the product roadmap, and implementing AI-powered development and product capabilities. The role requires rapidly learning unfamiliar technology stacks, improving legacy codebases without rewrites, operating independently, and partnering closely with general managers, operators, and customers.

Lead development of full-stack, mission-critical products using Angular, React, Node.js, and AWS serverless technologies. Own projects from product definition through deployment, integrate GraphQL APIs and machine learning systems, improve developer experience and CI/CD, collaborate with clinicians and researchers, participate in customer discovery, and mentor engineers while shaping technical architecture and engineering culture.

Lead architecture and hands-on development of Azure Kubernetes Service capabilities for AI workloads. Design secure, reliable, scalable distributed systems; coordinate engineering teams; define testing and deployment strategies; improve observability and operational readiness; investigate production issues; and mentor engineers while advancing engineering practices.

Lead development of scalable Java backend applications and high-availability cloud services. Design architectures, REST APIs, databases, caching systems, and distributed session infrastructure. Mentor engineers, drive technical initiatives, address performance and scalability challenges, and uphold quality and automation practices for endpoint management products.