Top Remote IT Jobs in Charleston, SC

Manage corporate system access, conduct access audits, support helpdesk and hardware operations, monitor SOC 2 compliance, and collaborate with DevOps and Security Engineering. Improve IT technology usage through requirements gathering, procurement, vendor planning, rollout, and stakeholder coordination. The role requires expertise in identity management, Apple-focused MDM, endpoint security, IT service management, compliance frameworks, and helpdesk ticketing systems.

Administers and supports PACS systems within an outpatient radiology practice, ensuring reliable technology operations, customer service, equipment use, policy compliance, and a safe work environment. The role may involve prolonged sitting, frequent standing and walking, and lifting up to 40 pounds. Employment requires successful drug and background screening.

Owns the architecture, configuration, integration, governance, and continuous improvement of inRiver, Bynder, and Boomi platforms. Integrates PIM, DAM, CRM, commerce, analytics, and ERP systems; develops and monitors Boomi processes; establishes master-data standards; leads technical projects, vendors, budgets, and delivery risks; and provides technical requirements, documentation, training, and executive communication.

Owns integrated delivery across four concurrent call orders within a large federal courts modernization program. Responsibilities include cross-program schedule, risk, dependency, governance, PI planning, executive reporting, contractual alignment, stakeholder communication, vendor coordination, and execution visibility. The role manages complex multi-vendor, SAFe-based delivery and supports capture and option-year planning. Remote work is available, with occasional travel and the ability to obtain a Public Trust determination required.

Administers Informix, MySQL, and other databases across cloud and hybrid environments. Responsibilities include configuration, maintenance, performance tuning, security remediation, replication, monitoring, Tier 3 support, schema changes, migrations, SQL data extraction, backup recovery testing, automation, compliance, and collaboration with engineering, architecture, security, and application teams.

Provides remote IT support to client administrators and end-users, focusing on phone services, configuration changes, and ticket handling through phone, email, and chat. Collaborates with team members to support customer success before and after sales. The six-month internship requires strong communication, problem-solving, organization, technical curiosity, and the ability to work independently in a home office.

IT Intern supporting employees with hardware, software, network, and device troubleshooting; assisting with installations, system maintenance, documentation, asset inventories, security monitoring, upgrades, cloud integrations, and process automation. The role also involves improving IT workflows, ensuring data security compliance, and collaborating on technology projects during a full-time summer internship.

Provides production database administration and support for mission-critical environments, including performance monitoring, incident response, root-cause analysis, security, and availability. Develops SQL Server database objects, ETL pipelines, dimensional models, data marts, dashboards, and Splunk monitoring solutions. Designs cloud and hybrid database architectures, performs data migrations, validates data integrity, and collaborates with stakeholders on technical requirements and analytics solutions within an Agile environment.

Leads Appen’s IT function, including support, enterprise technology, security governance, automation, vendor management and team development. Owns the IT roadmap, Microsoft 365 and SaaS environment, endpoint and identity controls, SOC 2 and ISO 27001 readiness, technology spend, and AI-enabled process improvement. Partners with executives, Engineering and Product to improve service delivery, eliminate manual work, manage risk and build a scalable, high-performing IT organization.

Provides second-line remote IT support for client end users, resolving escalated Windows, macOS, Microsoft 365, identity, Intune, application, printing, and collaboration issues. Manages onboarding, offboarding, access changes, endpoint deployment, patching, and security compliance. Works within ticket priorities and service-level objectives, documents solutions, creates knowledge articles, identifies recurring problems, and escalates infrastructure issues with detailed troubleshooting information.

Leads large-scale Oracle Cloud Infrastructure migration programs, managing schedules, budgets, risks, dependencies, governance, vendors, stakeholders, and cloud delivery teams. Oversees migration planning and execution for applications, databases, and infrastructure; drives change management, documentation, training, compliance, cost optimization, quality, and operational reporting. The role also supports cloud adoption, partner coordination, and predictable cutovers across multiple initiatives.

Supervises policy and legal affairs contractors while drafting, editing, researching, and reviewing policies, procedures, reports, responses, and executive materials. Coordinates approval processes, FOIA and congressional inquiry responses, interagency reviews, stakeholder communications, document management, and special projects. Oversees staff performance, onboarding, training, deliverables, timecards, reports, and process improvements. Supports research involving child welfare, foster care, mental health, family reunification, and underserved populations.

Leads the design, implementation, administration, integration, testing, and enhancement of Veeva Vault RIM. Translates business requirements into functional specifications, manages application roadmaps, supports GxP compliance, oversees internal and external technical resources, and drives system optimization. The role also provides troubleshooting, root-cause analysis, user support, data migration assistance for M&A activities, and technology guidance involving emerging technologies and AI.

Manages the IT and Security team, including helpdesk workflows, project roadmaps, compliance automation, access management, authentication standards, disaster recovery, vendor relationships, and enterprise system rollouts. Partners with product, engineering, and business leaders on security initiatives and complex technical changes. Maintains audit-ready security processes while overseeing remote IT operations, cloud security, identity tools, and technology spend.

Supports governance, monitoring, and IT General Controls for third-party relationships and external users. Responsibilities include due diligence, risk classification, identity and access oversight, least-privilege reviews, access certifications, MFA and DLP monitoring, incident escalation, remediation tracking, audit support, reporting, business continuity and disaster recovery activities, offboarding controls, process documentation, and stakeholder coordination across IT, security, compliance, legal, HR, and vendor management.

Develops and enhances Oracle EBS asset, financial, and logistics modules for Defense Logistics Agency programs. Builds integrations, RICE-FW interfaces, conversions, reports, and automation for capitalization, depreciation, valuation, and accounting processes. Supports testing, troubleshooting, reconciliation, audit traceability, technical documentation, and data mapping. Collaborates with functional SMEs on A2R requirements and process flows while integrating Oracle EBS with external asset and logistics systems.

Leads enterprise IT infrastructure and service operations, overseeing service-level performance, ITSM processes, project intake, business requirements, reporting, budgets, process improvement, escalations, and stakeholder relationships. Develops service delivery plans, manages providers and SLAs, supports healthcare and Medicaid contract compliance, and guides cross-functional initiatives. Hires, mentors, and develops a high-performing IT team while ensuring reliable services, operational efficiency, and alignment with organizational goals.

Supervises monitoring and compliance staff conducting grant-program reviews. Provides technical guidance, coordinates monitoring schedules and site assessments, reviews reports and corrective actions, analyzes compliance trends and risks, and recommends improvements. Oversees staff performance, training, deliverables, timecards, and reporting. Leads on-site and remote reviews, interviews stakeholders, evaluates program data and documentation, identifies technical assistance needs, and communicates findings to federal and recipient staff. Requires frequent domestic travel despite being fully remote.

Provides Tier II technical support for application, hardware, network, operating system, cloud, and mobile device issues. Responsibilities include troubleshooting escalated incidents, managing user accounts and permissions, administering IT systems, documenting solutions, monitoring system performance and security, mentoring junior staff, and supporting deployments, upgrades, and network projects. The role also analyzes incident trends and communicates technical solutions to users.

Own corporate IT operations while automating identity and access lifecycles, SaaS administration, endpoint security, compliance evidence generation, and IT support. The role includes Okta and SCIM provisioning, MDM management, OS patching, encryption baselines, license reclamation, audit readiness, runbook standardization, and Tier 1/2 support. The engineer will use Python, Bash, APIs, and AI coding tools to replace manual processes with policy-driven workflows and advise Finance and HR on tool administration.

Provides Tier II technical support for hardware, software, networks, servers, workstations, cloud environments, and mobile devices. Resolves complex issues, manages user accounts and permissions, monitors systems, documents processes, mentors junior staff, and supports software deployments, upgrades, and network projects. Requires strong troubleshooting, networking, communication, and customer service skills across Windows, macOS, Linux, and enterprise environments.

Provides production support and administration for mission-critical databases, including monitoring, incident response, root-cause analysis, performance optimization, and on-call coverage. Develops SQL database objects, Databricks lakehouse models, ETL pipelines, data migrations, dashboards, and data governance standards. Collaborates with stakeholders and development teams in an Agile environment while ensuring data integrity, scalability, security, and availability across AWS and hybrid-cloud platforms.

Supports a federal agency Regional Representative by monitoring grantee programs, reviewing financial and performance data, conducting site visits, analyzing compliance and program gaps, and preparing findings and recommendations. Provides technical assistance, supports grants management and regional initiatives, collaborates with government and community stakeholders, and performs research and functional analysis for federal decision-making.

Leads enterprise technology strategy and IT organization growth for a clinical-stage biotech transitioning to commercial operations. Oversees enterprise applications, CRM and ERP integration, cybersecurity, infrastructure, cloud systems, data governance, GxP validation, IT operations, vendors, budgets, and regulatory readiness. Partners across commercial, medical, manufacturing, quality, regulatory, clinical, finance, HR, and legal functions to support product launch, field-force deployment, scalability, compliance, and operational excellence.

Provides information security support for federal healthcare systems, including security architecture reviews, firewall and infrastructure initiatives, security impact assessments, mitigating controls, system security plans, SOPs, and POA&M remediation. Advises development teams and customer security organizations on federal security requirements, emerging practices such as Zero Trust and SBOM, network monitoring, authentication, and data security. The role is remote and requires passing an IHS background check for Public Trust eligibility.